Researchers successfully transplanted endometrial stem cells into the brains of mice with a Parkinson-like condition, restoring partially dopamine levels. This finding raises the possibility of women serving as their own stem cell donors and banks being established for men and women with Parkinson's disease.
Researchers found comparable obesity rates in white and black women living in similar social conditions. The study suggests that socioeconomic status and environmental factors play a significant role in explaining obesity disparities. Policies focusing on modifying social aspects of the environment may help reduce disparities among low...
Researchers have identified a new outermost layer of protection on bacterial spores, known as the 'spore crust', which may be a common feature of all spore-forming bacteria. This discovery was made using advanced microscopy techniques and offers new insights into the survival methods of these resilient organisms.
A new sensor developed by ORNL can detect chlorinated hydrocarbons in water with high accuracy and low cost, reducing the need for lengthy laboratory testing. The system combines membrane extraction and ion mobility analysis to provide a single, compact device for on-site monitoring of groundwater contaminants.
Genetic research suggests that elevated triglyceride levels are associated with a higher risk of heart disease. A major international consortium led by Dr Nadeem Sarwar and Professor John Danesh found this link in analysis of 350,000 people from 101 studies.
Researchers have extracted ancient DNA from 40,000-year-old Neanderthal bones to obtain a draft sequence of the Neanderthal genome. The findings suggest that modern humans interbred with Neanderthals shortly after migrating out of Africa, leaving genetic remnants in non-African genomes.
The LifeGene project uses Sweden's comprehensive health registries and genetic data to study the origin of disease, exploring interactions between environment, lifestyle, and heredity. The initiative gathers health and lifestyle information from 500,000 Swedes, aiming to improve diagnostics, treatments, and preventative recommendations.
Research finds that estrogen receptor status in HER2+ breast cancer is correlated with response to anti-HER therapies. Patients with ER+/HER2+ cancers may benefit more from PI3K/AKT inhibitors, while ER-/HER2+ patients may see worse outcomes with hormonal therapy alone.
Researchers at Emory University have discovered that simple peptides can organize into bi-layer membranes, a 'missing link' between pre-biotic Earth's chemical inventory and the scaffolding essential to life. This finding may also shed light on protein assemblies related to Alzheimer's disease, Type 2 diabetes, and other serious ailments.
Researchers at the University of Leeds have identified PYM as a key protein involved in the replication and spread of Kaposi's Sarcoma-causing viruses. Blocking interactions between PYM and viral proteins could lead to new treatment options for this disease.
Four ESCEO-AMGEN Osteoporosis Fellowships valued at $50,000 each were awarded to outstanding researchers in osteoporosis, with projects focusing on vitamin D status, osteoporosis treatment preferences, and ephrin B2 system. The Fellowship Programme aims to advance clinical care and prevention through training physicians and PhDs.
The article reviews HealthMap's H1N1 surveillance efforts, demonstrating the value of informal data in producing a comprehensive real-time global health picture. The analysis identified disparities in international public health systems, with countries having high GDP reporting confirmed cases faster than those with low GDP.
Researchers at University of Michigan find that hand-washing reduces influence of past behaviors and decisions with no moral implications. Washing hands results in reduced buyer's remorse and less rosy evaluations of choices.
Researchers at Yale University have discovered that endometrial stem cells can repair brain cells damaged by Parkinson's disease, potentially treating women with the condition. The study, published in Journal of Cellular and Molecular Medicine, found that these stem cells can differentiate into dopamine-producing nerve cells.
A new study published in the International Journal of Behavioral Medicine found that losing weight quickly, rather than gradually, is associated with larger long-term weight losses and reduced risk of weight regain. Women who lost weight at a faster rate were more likely to achieve clinically significant weight loss and maintain their ...
Researchers at Boston University develop a new metamaterial device that can detect and control terahertz radiation, paving the way for safer medical and security scanners. The device uses an array of split-ring-resonators to manipulate electromagnetic properties of THz energy.
The University of Missouri received an $8.5 million grant to explore the role of microcirculation in cardiovascular diseases, a leading cause of death. The research will focus on the smallest blood vessels in the body and their contribution to health and disease.
Dr. Mandalakas will analyze social and economic barriers to implementing Isoniazid preventative therapy in children with latent tuberculosis infection in South Africa. She aims to promote the practical implementation of preventive therapy to improve child health outcomes.
A new study found that long-term use of DMPA injections increases the risk of bone fractures in women under 50, with a 50% higher risk for users of progestin-only contraceptives. The results suggest that combined estrogen-containing oral contraceptives do not increase fracture risk
A genome-wide association study has identified three new genetic loci significantly associated with quantitative eye colour variation, explaining over 50% of the trait's variance. The study used high-resolution full-eye photographs to quantify human eye colour along multiple dimensions.
A $2.7 million NIH grant will help identify how cognitive impairments affect heart failure patients' self-management behaviors, aiming to improve patient health and reduce medical costs. The four-year study will evaluate the relationship between cognitive abilities and self-management behaviors.
Researchers have discovered prehistoric fish trails, made by the ancient species Notogoneus osculus, in Wyoming's former Fossil Lake. The study provides evidence that fish were able to survive on the lake bottom despite low oxygen levels.
Scientists have developed technology to screen newborns for spinal muscular atrophy (SMA), a lethal disease caused by gene mutations. Effective screening may allow parents to access proactive treatments before symptoms become irreversible.
Researchers at the University of Michigan have built a more efficient Rydberg atom trap, which could enable faster quantum computers. By trapping giant Rydberg atoms, they can create stronger quantum circuits and solve complex problems that conventional computers cannot.
New research suggests that radio frequency identification (RFID) could be used to provide critical information on casualties and losses in the immediate aftermath of an earthquake. RFID readers installed at entry and exit points and around critical areas in a building could help rescue personnel locate trapped individuals more precisely.
John A. Burns has been awarded the W. T. and Idelia Reid Prize in Mathematics for his fundamental contributions to computational methods and applications in control, design, and optimization of infinite dimensional dynamical systems. He is currently working on reducing energy consumption and greenhouse gas emissions through modeling, s...
Researchers developed a simple genetic test using three genes to classify breast cancer into sub-types, highlighting the importance of molecular classification in treatment outcomes. The study's findings suggest that these models are robust and can aid clinicians in making therapeutic decisions.
A new study compares induced pluripotent stem (iPS) cells and embryonic stem cells in modeling fragile X syndrome, a genetic disorder. The research reveals that the two cell types behave differently in the disease model, with iPS cells not fully replicating the gene silencing process.
Ultrasound imaging is a highly effective and non-invasive test for characterizing peroneal nerve damage in patients with foot drop. High-resolution ultrasound was found to be more effective than EMG and MRI for evaluating common causes of foot drop, making it the recommended first-line imaging choice.
A team of scientists discovered that seismic slip on the Central Peru Megathrust is caused by a combination of earthquakes and non-seismic creep. This finding indicates that movement along this subduction zone is more complex than previously thought.
Researchers evaluate promising new potato varieties for improved quality and longer storage life, targeting up to 10 months. They've identified genetic causes for early sprouting and are working towards non-chemical solutions.
A recent study published in the journal Surgery found that mechanical bowel preparations (MBPs) do not reduce perioperative infectious complications in patients undergoing pancreaticoduodenectomy. The researchers analyzed data from over 200 patients and concluded that MBPs have no clinical benefit for this procedure.
Researchers have developed a microscope-based cell scanner to measure physical parameters in Petri dishes, allowing scientists to investigate fat cells at the cellular level. This tool enables rapid assessment of individual cell changes under experimental conditions, providing clues about treatment toxicity or effectiveness.
Mary Shaw, a renowned computer scientist at Carnegie Mellon University, has been selected as the first recipient of the IEEE Distinguished Educator Award. She is recognized for her innovative curricula in computer science, which challenge educators to teach new forms of software development.
A Saint Louis University study shows that a residential summer weight-loss camp improves the health of obese children by reducing their weight, BMI, and blood pressure. The program also boosts their physical fitness and self-esteem, as they connect with peers who share similar struggles.
A new study reveals that the human immune system's defences against dengue fever can actually help the virus infect more cells. This finding could lead to the development of an effective vaccine by avoiding certain antibodies produced in response to the virus.
Researchers have developed a powerful new technique for analyzing genome data from single tumor cells. The breakthrough allows scientists to study the biology of tumor development and identify dangerous cells in small samples. By profiling individual cells, researchers can understand genetic changes that occur as cancer progresses.
A study found that teen girls disclose more information about their dating habits than boys, with mothers being the preferred confidant. However, when it comes to issues involving sex and unsupervised activities, teens from both sexes are equally close-mouthed.
Researchers discovered that neuronal stem cells exist in the human brain, even in adulthood, and can form new neurons. Physical activity and pathological stimuli like epileptic seizures reactivate dormant stem cells, promoting the formation of new neurons.
A study led by Loyola University Health System researcher found that 54% of cirrhosis patients scored below the 10th percentile for their age and education on a test measuring neurocognitive abilities.
The study found that only 88 Neandertal proteins differ from human proteins, indicating a high degree of similarity between the two species at the proteome level. This discovery suggests that many Neandertal functions may be neutral or have been lost over time.
A study found that ultrasound can effectively diagnose muscle tears in soccer players during games, allowing for immediate play cessation. This non-invasive imaging modality helps prevent further injuries by detecting partial or complete muscle tears on-site.
Researchers at UAB have made a breakthrough in understanding age-related memory loss, with histone deacetylase inhibitors showing great promise in both normal age-related decline and Alzheimer's disease. The findings provide important proof-of-principal for potential therapeutic interventions to improve quality of life in the aged.
Carla Finkielstein, a Virginia Tech Assistant Professor, has received the Minority Scholar Award in Cancer Research from the American Association for Cancer Research. The award recognizes her contributions to advancing cancer research and increasing diversity in the field.
Researchers at Case Western Reserve University have discovered a direct link between neural activity in an insect's brain and changes in behavior. The findings suggest that cockroaches can control their speed with their brains, which could inspire the development of more adaptive robots for search and rescue and space exploration.
A new CT technique eliminates the need for X-rays in trauma patients with possible spinal fractures, lowering cost and radiation exposure. The study found that 19% of patients with reformatted CT data also had unnecessary X-rays, resulting in a significant additional radiation dose and cost.
A study found that preoperative MRI can help surgeons identify the neurovascular bundle and spare it during RALP, leading to better erectile function outcomes. The technique has improved surgical decision-making without compromising oncological results.
A new technique called z-axis modulation can significantly reduce the radiation dose associated with unenhanced computed tomography (CT) scans of the head. By applying this simple method, radiologists can achieve a 35% reduction in patient dose while maintaining optimal image quality and noise levels.
Researchers analyzed office referrals across over 1,500 US schools to identify patterns of student discipline for different behaviors. Elementary, middle, and high school students are disciplined differently, with fighting, defiance, and tardiness being common reasons.
A €2.75 million programme aims to tackle cultural barriers hindering adolescent reproductive health services in Africa. The initiative will analyse current provision and develop targeted interventions to enhance reach and effectiveness.
A recent study presented at the ARRS Annual Meeting found that whole body MRI is highly accurate in detecting breast cancer metastases. The test identified bone metastases in 47 out of 99 patients with known breast cancer, while a chest X-ray only detected them in 24 patients.
Researchers have assembled the first comprehensive DNA sequence of an amphibian genome, which will aid in studying embryonic development and its implications for preventing birth defects and treating various human diseases. The Xenopus tropicalis frog genome sequencing provides a blueprint for understanding gene function and expression.
Research reveals hepcidin-25's presence in various biological fluids, including saliva, bile, ascitic, and pleural fluid. This finding has implications for understanding anaemia of chronic disease, iron overload, and infectious disorders.
Researchers at Rice University and the University of Cambridge have created a computer model that accurately describes the behavior of three regulatory proteins in hematopoietic stem cells. The Scl-Gata2-Fli1 triad is thought to be the master-level regulator for these self-renewing cells, which produce new blood cells.
A nationwide study found that nearly a quarter of women between 25 and 45 consider themselves 'OK either way' when it comes to getting pregnant, contradicting the long-held notion that women are always trying to get or not get pregnant. This ambivalence was linked to higher numbers of ideal children and slightly more religious attitudes.
Fluoroscopic (X-ray) guided steroid injections offer a safe and effective alternative to conventional treatment of hamstring tendonitis. The study found that 11 out of 16 patients showed major improvement after treatment, with no immediate or long-term complications reported.
The published Neandertal genome sequence shows significant genetic differences between Neandertals and modern humans, suggesting some interbreeding in the Middle East. Approximately 1-4% of the modern human genome is estimated to be from Neandertals, potentially limiting the extent of interbreeding.
A patient with past history of hepatocellular carcinoma (HCC) presented with renal tumor 12 years later, revealing solitary recurrence of the initial HCC. This case emphasizes the need for early diagnosis of metastatic HCC to alter treatment planning and improve patient outcomes.
A study found that shoppers frequently estimate how much they'll spend on unplanned items and are remarkably accurate. In-store slack refers to the mental budgeting strategy used by consumers to accommodate unforeseen purchases.
Young people with inflammatory bowel diseases are at increased risk of fracture due to low bone mass and poor bone architecture. This is attributed to factors such as poor nutrient absorption, glucocorticoid medication use, and altered trabecular bone tissue microarchitecture.