Researchers found that inactivating the NLRP3 protein can increase the effectiveness of therapeutic cancer vaccines. This discovery may lead to more effective cancer treatments and is the first to link immature myeloid cells, NLRP3, and vaccine response.
A new Université de Montréal study examines early indicators of a criminal lifestyle in preteens. The findings reveal that children with conduct disorders are six times more likely to sell illicit drugs, nine times more likely to join a gang, and eight times more likely to be arrested.
Eberhard Möbius, a professor at the University of New Hampshire, has been recognized as a Fellow of the American Geophysical Union for his exceptional scientific contributions to space plasma physics. His work on pickup ions in the solar wind and the development of state-of-the-art instrumentation have far-reaching applications in gala...
Research by University of Guelph scientists reveals that female squirrel behavior is driven by opportunities for mating, rather than genetic influences. The study found that females tend to mate with multiple males in a single heat cycle, despite potential risks such as increased energy expenditure and predator exposure.
Researchers at Duke University Medical Center have identified a major pathway that infected cells use to root out Epstein-Barr virus infections, which can cause cancer in people with compromised immune systems. The study found that two enzymes play a critical role in mediating this response and preventing unchecked cell growth.
A new research paper published in the Journal of the National Cancer Institute reveals a genetic mutation that leads to abnormal metabolic processes in gliomas, potentially leading to targeted therapies. The study shows that almost all tumors with IDH mutations have the same methylation pattern.
Adhering to UK dietary guidelines on fruit and vegetable consumption, fibre, fats, and salt could prevent or delay up to 33,000 deaths annually. Reducing these components' intake significantly impacts mortality rates.
Scientists challenge conventional wisdom on fluoride's effectiveness in preventing tooth decay, finding the protective shield on teeth is just 6 nanometers thick, sparking questions about its ability to protect teeth.
Researchers at NC State University create core/shell nanoparticles with gold and silver, as well as alloy nanoparticles, using the 'digestive ripening' technique. This method allows for control over optical properties of the resulting nanoparticles.
A new report by Brown University sociologists John Logan and Brian Stults found that despite increased diversity, American neighborhoods remain segregated. The US2010 project analyzed data from the American Community Survey to track changes in society over time.
A team of researchers from the University of California - San Diego discovered a molecule dubbed 'longdaysin' with the most potent effects on the biological clock, slowing it down by more than 10 hours in larval zebra fish. The compound could be used to treat severe sleep disorders or quickly reset jet-lagged travelers' clocks.
Researchers found that individuals with multiple group memberships recover faster from physical challenges and are more resilient in the face of stress. This suggests that belonging to several groups can provide psychological strength and promote overall well-being.
Scientists have discovered that cilantro's (E,E)-2,4-Undecadienal compound effectively eliminates the strong smell of chitlins. The ingredient can suppress odor at very low concentrations, equivalent to about 10 drops in an Olympic-size pool.
A new software tool visualizes biomechanical data to help professionals understand and address mobility challenges. This improves diagnostic, therapeutic, communication, and education procedures, leading to better-designed products and healthcare strategies. The tool has the potential to enhance quality of life for older people.
The Malaspina 2010 expedition aims to assess the impact of global change on the ocean and explore its biodiversity. Over 250 researchers will study temperature, salinity, and nutrient concentration in various ocean regions.
Researchers found that papers with authors in the same building were cited 45% more than those in different buildings. The closer first and last authors are located, the more impactful the paper is, according to a new Harvard study.
A University of Illinois research team has developed a strain of yeast that can efficiently ferment galactose, a key component of seaweed, making it a viable option for biofuel production. The discovery improves the economic viability of marine biofuels by increasing fermentation rates and reducing production costs.
A study published in PLoS Biology found that p53 determines organ size by regulating tissue growth. The protein's activation in response to stress leads to a coordinated reduction in the growth of healthy tissues, allowing damaged areas to repair themselves.
New NASA research reveals a significant increase in plant consumption globally, driven by growing populations and economic development. The global demand for land-based materials has risen from 20% to 25% over the past decade, with per capita consumption increasing in some regions.
A recent study published in HortScience found that Bounce fabric softener sheets can repel adult gnats, with a mean proportion of fungus gnat adults collected being significantly lower in sample compartments containing dryer sheets. The study attributed the effect to volatile compounds such as linalool and beta-citronellol.
A new colonoscopy skills assessment tool, MCSAT, was developed to evaluate cognitive and motor skills in trainees. The tool provides a standardized method to assess individual progress and establish normal learning curves.
Aaron Hertzmann, a professor at the University of Toronto's Department of Computer Science, has received the 2010 Steacie Prize for his exceptional contributions to computer graphics and machine learning research. His work focuses on applying machine-learning techniques to resolve complex problems in computer graphics.
A study by the Spanish Railways Foundation found that high-speed trains, such as the AVE, consume 29% less energy and produce 31kg less CO2 per passenger compared to traditional trains. The main advantage of high-speed lines is not in reducing fossil fuel consumption, but in attracting passengers who would otherwise travel by air or car.
A new study found that attending Alcoholics Anonymous at least once a week increased the chance of a positive outcome for incarcerated women returning to the community. The research also showed a significant decrease in alcohol-related consequences and overall drinking days among those who attended AA regularly.
Researchers from Arizona State University are studying Anolis lizards to understand their ability to regenerate tissues, with potential applications in treating human osteoarthritis and spinal cord injuries. The team is using molecular methods and the lizard's genome sequence to identify key genes involved in regeneration.
A study by University of Wisconsin-Madison sociologist Shane Sharp found that prayer can help victims of violent relationships cope with their emotions and find comfort through venting and positive self-perceptions. Prayer also serves as a useful distraction, allowing individuals to momentarily escape from anxiety and feelings of anger.
A Swedish case study reveals how Alzheimer's disease progresses, with high amyloid plaque levels at early stages and declining brain energy. The discovery sheds light on the role of nicotinic receptors and neuroinflammation in the disease, offering new insights for diagnosis and treatment.
A new study improves brain-machine interface control by adding a robotic arm providing kinesthetic information, enhancing the design of 'wearable robots' for paralyzed patients. This approach may help spinal cord injury patients operate computers and robots using only their thoughts.
Scientists successfully removed amoxicillin, a top five US-prescribed drug, and other substances like nitrates and dyes from water samples using Octolig. The process has implications for reducing environmental contamination and point-source pollution.
Consumers who purchase luxury items with unique design elements are more likely to experience aesthetic incongruity resolution, where they make additional purchases to match the item. This can lead to a larger financial expenditure than initially anticipated.
A new nonverbal response card has been developed to improve the accuracy of data collection on teenage sexual behavior. The device reduces reporting bias and provides confidential responses, resulting in higher accuracy rates for HIV risk assessment.
Research led by McGill University Health Centre found that nearly 70% of parents reported feeling closer to their babies after reading to them in the NICU. The practice also encouraged parents to continue reading at home, with those who read to their child in the NICU three times more likely to do so.
The NASA Interstellar Boundary Explorer (IBEX) spacecraft has made the first-ever images of the plasma sheet and magnetotail in the Earth's magnetosphere. The data suggests a piece of the plasma sheet was bitten off and ejected down the tail, revealing dynamic interactions that have never been seen before.
A new study reveals that fighter pilots exhibit superior cognitive control, accuracy, and response to distracting information. Their brains also show distinct structural alterations in white matter connections, which may be linked to expertise in certain aspects of cognition.
A combination therapy of entinostat and erlotinib showed improved survival rates in patients with advanced non-small cell lung cancer (NSCLC) and elevated E-cadherin levels. The treatment was more effective than using erlotinib alone, leading to a large improvement in survival for patients with high E-cadherin expression.
Marine biotechnology has the potential to address critical future challenges such as sustainable food and energy, new drugs and health treatments, and industrial materials. The European Science Foundation predicts that with the right actions taken now, Europe could become a global leader in marine biotech by 2020.
Researchers developed a new intense 13.5-nm light source using tin and lithium plasmas, which can reduce feature size by an order of magnitude, resolving the fundamental limit in semiconductor manufacturing. The technology has shown promising results, with tin plasmas producing twice as much emission as lithium plasmas.
Researchers used zebrafish to track the behavior of cancer cells and immune cells, discovering that cancer cells produce hydrogen peroxide to attract immune cells. This co-option of the immune system allows tumors to grow and spread, but blocking this interaction can prevent tumor formation.
Researchers at UT Southwestern Medical Center discovered gene expressions in lung tumors and normal tissue that predict patient survival time and guide effective treatments. The study found specific nuclear receptors associated with good prognosis and identified potential drug targets for personalized therapy.
Scientists from Technical University of Munich are investigating how robots can help workers pack large TV sets, reducing costs and improving competitiveness. The CustomPacker project aims to create a safer and more efficient packaging station through human-robot cooperation.
A team of researchers led by David Furbish from Vanderbilt University is studying the erosion of Locke Island, which has been alarmingly eroding away since the 1970s. The island's difficulties began when the east bank of the river adjacent to it collapsed, causing a landslide that pinched down the channel flowing around the island.
Researchers have identified a key inhibitory role for the IL-1 signaling pathway in the human innate immune system, revealing its impact on inflammatory bowel disease (IBD) and anti-inflammatory cytokine production. The study suggests that certain drugs used to treat conditions like rheumatoid arthritis may be harmful to IBD patients.
A randomized controlled trial found that a lung protective strategy increased the number of lungs eligible for donation by nearly doubling it compared to conventional ventilation. This method included lower tidal volumes and higher positive end-expiratory pressure levels.
The Affordable Care Act offers comprehensive health benefits to 8.6 million uninsured adults ages 50-64 and 9.7 million underinsured adults. Baby boomers will gain improved coverage through essential benefit standards, limits on out-of-pocket spending, and elimination of lifetime benefit limits.
This special section of Perspectives on Psychological Science explores how psychologists can avoid stigmatizing groups by framing individual and group differences as strengths. Experts discuss the importance of challenging biases and stereotypes in research, teaching, and advocacy to promote a more inclusive field of psychology.
Researchers found that mechanical shaking was more effective than manual shaking in removing yellowjacket queens from Christmas trees. The study also showed that pre-harvest insecticide sprays can be 100% effective in killing yellowjacket queens, even after heavy rainfall.
Researchers at Scripps Institution of Oceanography have discovered a unique defense mechanism in the clusterwink snail, which uses its shell to scatter and spread bright green bioluminescent light. The study found that this diffused light may be used to create an illusion of a larger animal, deterring predators.
A new study found that deep brain stimulation (DBS) targets the same class of neuronal cells known to respond to exercise and Prozac, leading to an increase in new neurons in the hippocampus. The targeted area, anterior thalamic nucleus, may provide a guide for designing better treatments.
Researchers launched a rocket into aurora above Norway to measure the complex physics behind 'satellite drag'. The data will provide essential information for advancing understanding of neutral upwelling and its association with visible aurora phenomena.
A study of 1,106 Mexican heritage youth found that perceived ethnic discrimination and acculturation stress increase with age and lead to higher risks of alcohol, cigarette, and marijuana use. The study suggests that prevention programs should address discrimination and encourage effective coping strategies for young people.
Scientists have discovered that many people with asthma actually had the mould growing in their own lungs. A study by University of Leicester researchers found that 6 out of 10 people with asthma who were allergic to a common mould grew the mould from their sputum, leading to fixed narrowing of the airways.
A Swedish study reveals that children are exposed to an average of 50 TV adverts for food per week, dominated by fast food and sweets. The research suggests a link between food advertising and unhealthy food choices among children.
A USGS study assessed the McKenzie River in Oregon, measuring optical properties to understand dissolved organic carbon and its impact on drinking water quality. The results indicated that sources of dissolved organic carbon originated upstream and were linked to human activity.
Researchers Francisco Úbeda and Edgar Duéñez found that moral corruption and power asymmetries are necessary for overall societal cooperation. Without law enforcers, individuals have less incentive to cooperate, while without power and corruption, law enforcers lose their motivation to do their job.
The cyanobacteria Cyanothece 51142 produces hydrogen gas at a rate roughly 10 times higher than its nearest competitors due to its unique genetic makeup and metabolic processes. This ability allows the microbes to survive on air, water, and sunlight alone.
Researchers have fabricated 2-nm nanochannels that significantly enhance ion transport, improving power density and practical energy density of fuel cells and batteries. The smaller geometry and stronger hydration force are expected to further enhance ion transport in even smaller hydrophilic nanotubes.
A new study shows that attending Alcoholics Anonymous meetings increases spirituality, leading to better alcohol outcomes and improved recovery rates. The research suggests that spirituality is an important factor in the multi-faceted recovery from alcohol-use disorder, but it's not the only method used.
Scientists have discovered how the human papilloma virus (HPV) triggers cancer in the cervix and mouth, potentially leading to new treatments. The study found that HPV activates a protein called Cdc42, which is already implicated in various cancers, including tumour spread.
Medical students and doctors face challenges accessing and incorporating evidence into their practice as the available evidence base grows. A new HEA-funded mini-project will explore decision-making processes about where to obtain information, aiming to improve clinical time management and patient care.
A unique orangutan rescue project in Bukit Tigapuluh is at risk due to selective logging concessions by Asia Pulp & Paper/Sinar Mas Group. The project has been deemed critical for tiger conservation, with over 30 tigers and 150 elephants calling the forest home.