Researchers at the University of Exeter have developed a new screen to isolate virulent parts of pathogenic bacteria, enabling quicker identification of key areas for vaccine development. The technique has been used to study Burkholderia pseudomallei, a deadly human disease-causing bacteria.
Researchers discovered that in a South American fish species, males with less desirable traits like brawn and stealth can still gain a mating advantage. In contrast, females prefer more striking colors, but also prioritize winning male combat, making color diversity surprisingly resilient.
SourceSyracuse University·JournalBMC Evolutionary Biology·DateDec 23, 2010
Researchers have isolated and characterized adult fat cell-derived stem cells, which maintain their stem cell characteristics and could aid in tissue regeneration. The study's findings suggest that these cells may be useful for cell-based therapies and represent a promising area of research for plastic surgery applications.
SourceCell Transplantation Center of Excellence for Aging and Brain Repair·JournalCell Transplantation·DateDec 23, 2010
Scientists at UMass Chan Medical School discovered that paternal diet can reprogram lipid metabolizing genes in offspring, increasing the risk of diabetes and heart disease. The study suggests that epigenetic inheritance plays a significant role in complex diseases.
SourceUMass Chan Medical School·JournalCell·DateDec 23, 2010
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Researchers found that altering a specific gene in mice mimicked the effects of endurance training on their heart muscle cells. The genetically altered mice showed improved resistance to cardiac stress and had more robust cardiomyocytes, which played a crucial role in their increased exercise capacity.
SourceDana-Farber Cancer Institute·JournalCell·DateDec 23, 2010
Researchers at Sanford-Burnham Medical Research Institute have unraveled the relationship between MITF and ATF2, a transcription factor involved in melanoma development. The study reveals that the ratio of ATF2 to MITF in melanoma cells can predict survival in melanoma patients.
SourceSanford Burnham Prebys·JournalPLOS Genetics·DateDec 23, 2010
Scientists at UC Davis have identified a gene called Cullin1 that acts as a biochemical gatekeeper, controlling whether or not pollen from related wild species can fertilize tomatoes. This finding has significant implications for plant breeding and understanding reproductive biology in the Solanaceae family.
SourceUniversity of California - Davis·JournalScience·DateDec 23, 2010
Researchers discovered that heat shock protein 90 affects a large portion of the yeast genome, revealing multiple traits simultaneously and instantly. This allows for rapid evolution of interdependent traits, leading to a better adaptation to stressful environments.
SourceWhitehead Institute for Biomedical Research·JournalScience·DateDec 23, 2010
Researchers at UCLA's Jonsson Comprehensive Cancer Center have found a new mechanism that regulates protein stability in cells, triggered by the GSK3 enzyme. This discovery could lead to potential new treatments for cancer, particularly colorectal cancers and other forms of cancer.
SourceUniversity of California - Los Angeles Health Sciences·JournalCell·DateDec 23, 2010
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A new study documents the process through which journalists fought for recognition of their work in major newspapers. The research found that it took over 70 years for bylines to become an established practice, and highlights the impact on the news industry and public perception of journalists.
SourceAmerican Associates, Ben-Gurion University of the Negev·JournalJournalism·DateDec 23, 2010
A new study in mice suggests that exercise turns on a genetic program that leads the heart to grow as heart muscle cells divide. Researchers identified a key transcription factor involved in this process, which may have clinical implications for those with heart failure or other conditions.
Scientists found that AMPK, a metabolic master switch, triggers autophagy by activating the enzyme ATG1. This process helps cells recycle debris and survive starvation better, which is significant for aging-related diseases like type II diabetes and Parkinson's disease.
Dutch researchers have successfully controlled qubits using electrical fields instead of magnetic ones, paving the way for a future super-fast quantum computer. They also embedded these qubits into semiconductor nanowires, which are ideal for quantum information processing.
SourceDelft University of Technology·JournalNature·DateDec 23, 2010
A new model, fullPIERS, predicts adverse maternal outcomes in pre-eclampsia with high accuracy and identifies risk categories for clinicians. The model is built on six variables and performs well in predicting outcomes within 48 hours of hospital admission.
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A new study from the University of Haifa found that high levels of emotional intelligence empower positive attitudes and reduce negative behavior in private sector workplaces. However, this effect was not observed in the public sector, where organizational politics and stress may offset the benefits of emotional intelligence.
SourceUniversity of Haifa·JournalPublic Administration Review·DateDec 23, 2010
A new study found that mice sired by fathers on a low-protein diet exhibit changes in metabolic genes, passed down via the sperm, and associated with improved cholesterol metabolism. This suggests transgenerational reprogramming of metabolism, challenging traditional views on the impact of parental nutrition.
Scientists at IRB Barcelona discovered that some brain tumors in fruit flies use the genetic program of germline cells to grow. Silencing specific genes leads to healthy brains, highlighting their crucial role in tumor development. This finding offers new insights into cancer research and potential treatment approaches.
SourceInstitute for Research in Biomedicine (IRB Barcelona)·JournalScience·DateDec 23, 2010
A new RAND Corporation study found that electronic medical records have only a limited impact on improving the quality of hospital care. Hospitals with basic electronic health records showed a significant increase in quality of care for patients with heart failure, but no similar gains were noted among those with advanced electronic he...
SourceRAND Corporation·JournalThe American Journal of Managed Care·DateDec 23, 2010
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Researchers at Texas A&M University have found that bacteria incorporate foreign DNA from invading viruses into their own regulatory processes, developing resistance to antibiotics. This discovery sheds light on how bacteria have developed immunity over millions of years.
SourceTexas A&M University·JournalNature Communications·DateDec 23, 2010
Researchers developed a new device that manipulates and detects spins in semiconductors at high temperatures, promising advances in low-power electronics. The device has potential applications in fields like energy transfer, secure communications, and sensor development.
A vegetarian diet has been shown to lower blood and urine phosphorous levels in patients with chronic kidney disease. The study found that grain-based protein sources, such as those found in vegetables, may help reduce the risk of accumulating toxic levels of phosphorus in the body.
SourceAmerican Society of Nephrology·JournalClinical Journal of the American Society of Nephrology·DateDec 23, 2010