A new meta-analysis of clinical trials finds that rosiglitazone is associated with a significantly increased risk of myocardial infarction, while the risk of cardiovascular death was not elevated. The study suggests an unfavorable benefit-to-risk ratio for the diabetes drug, raising concerns about its safety.
Researchers tracked bumblebee movements in Arctic conditions, finding that bees work a day shift and retire before midnight. The study suggests that bees may have an internal sense of time based on light intensity or temperature changes.
According to a study published in Archives of Internal Medicine, increased bicycle riding and brisk walking among premenopausal women were linked to reduced weight gain, particularly for those who are overweight or obese. The study found that even low levels of cycling, such as five minutes per day, can have significant health benefits.
Darby and Celia are weakening tropical storms in the Eastern Pacific, with expected minimum central pressures of 1004 millibars and 1005 millibars. Both storms are forecast to continue weakening over the next day or two before becoming remnant low pressure areas.
Researchers discovered that asbestos exposure leads to the release of high-mobility group box 1 protein (HMGB1), which promotes tumor growth and inflammation. Elevated levels of HMGB1 in patients exposed to asbestos may enable simple serological testing to identify at-risk individuals.
Trade in coral and tropical fish is substantial and growing, removing millions of animals a year. The US can leverage its market power to reduce the environmental impact by protecting more species and promoting humane sales.
A multi-institutional team sequenced the body louse genome, revealing a simplified genetic toolkit that sheds light on its unique biology. The study found that the body louse has a reduced list of detoxification enzymes, making it an attractive model for studying resistance to insecticides.
The study found substantial differences between women with endometriosis and controls, with lost work productivity averaging ten hours per week. Quality of life was also significantly impaired, except for physical functioning and mental health.
Patients admitted to teaching hospitals for end-of-life illnesses receive high-quality medical care, but more family communication is necessary. The study found that timely efforts to keep patients comfortable and better discussions about goals of treatment can improve the quality of care.
A study by UT Southwestern Medical Center researchers found that family-centered rounds improve patient-family involvement in care and provide senior physicians with opportunities to train medical trainees. Benefits include increased parental understanding of discharge goals and improved team communication.
A study by researchers funded by JDRF found that the serotonin hormone increases insulin-producing beta cells during pregnancy. This discovery could lead to the development of new drugs to promote beta cell regeneration in people with type 1 diabetes, offering a potential cure for the disease.
Researchers will study challenges faced by pre-K and elementary readers, as well as high school students struggling with reading comprehension. The project aims to develop new assessments and instructional activities to help teachers put the study's findings into practice.
A recent study by University of Calgary professor Charlene Elliott found that 53% of baby and toddler foods have excessive sugar content, with over half meeting the criteria for poor nutritional quality. The study also revealed a 'halo effect' in adult perceptions of these products, highlighting the need to carefully examine ingredient...
A new study published in the Journal of Health and Social Behavior found that adolescent girls who perceive themselves as overweight but have a healthy weight are more likely to experience depressive symptoms than those with actual obesity. Additionally, underweight boys are also at high risk for distress. The researchers suggest that ...
A study estimates that 1.58 million US cancer survivors live with their 2.85 million children, and 562,000 minor children live with a parent in early cancer treatment and recovery. Most of these survivors are female, married, and under 50 years old.
A study published in Biomed Central (BMC) Genomics found that high-phenolic-content olive oil modifies genes involved in the inflammatory response, potentially reducing heart disease risk. The researchers tracked gene expression in blood cells after consuming two virgin olive oil-based breakfasts with varying phenolic compound content.
Researchers found that statin use reduced prostate cancer recurrence by 30 percent, with higher doses associated with a greater risk reduction. Men taking higher doses of statins had a 43-50% lower risk of recurrence compared to those taking lower doses.
A Purdue University researcher has identified a yeast gene that increases the production of a compound slowing aging and delaying microbial decay in tomatoes. This discovery may lead to extended shelf life for most fruits by an additional week, benefiting areas with limited access to fresh produce.
The Phase I trial found low-dose, multi-dosing regimens of BCG vaccination safe in individuals with type 1 diabetes, with no severe reactions reported. A Phase II clinical trial is planned to investigate the safety and efficacy of BCG vaccination as a therapeutic agent for type 1 diabetes prevention or reversal.
A mathematical model suggests that aggressively treating low blood pressure and cholesterol levels may harm some patients with diabetes. The study found that only a small proportion of patients at average risk received significant benefits from intensive treatment.
Researchers at the University of Strathclyde found that a substance called beeglue, originating from beehives in the Pacific region, was active against MRSA. The study isolated two compounds, Propolin C and Propolin D, which showed good activity against all MRSA strains tested.
The NASA Center for Climate Simulation (NCCS) has been introduced at NASA's Goddard Space Flight Center, offering enhanced computing capacity and data interaction technologies. This will support NASA's growing climate data needs and enable climate simulations and predictions.
Dr. Seong Park's research found that manure provides higher economic returns than chemical fertilizers due to its multiple essential crop nutrients and lower costs. The study showed that swine effluent was the most cost-effective option, with breakeven prices lower than anhydrous ammonia.
The University of Michigan predicts a larger-than-average Gulf dead zone this year, with a range of 6,500 to 7,800 square miles. The impact of the Deepwater Horizon oil spill on the size of the dead zone is unclear, but it could either increase or decrease due to various factors.
The University of Texas at Austin will design and oversee a monitoring plan for a carbon capture and storage demonstration project in southeast Texas. The project aims to reduce emissions of CO2 from a coal-fired power plant and demonstrate advanced technology for enhanced oil recovery.
Researchers at Harvard University have developed programmable matter by folding, allowing a single sheet to transform into a boat- or plane-shape. The technology uses origami techniques and features smart cups that can adjust to liquid levels and other tools with multiple functions.
Scientists have discovered that movable sequences of DNA, known as L1 retrotransposons, are much more common than previously believed. This finding has significant implications for understanding the causes of genetic diseases.
A study of clinical measures associated with end-of-life care in hospitalized patients identified opportunities for improvement. Communication between clinicians and patients, dyspnea assessment, and pain management were found to be areas needing attention.
A new study on Chile's nationwide school voucher program found that it increased high school graduation rates by 3.6 percent, and college-going rates by 3.1 percent. The reforms also led to a modest reduction in earnings inequity and an increase in the demand for private subsidized schools.
An international consortium of scientists has identified 12 new gene variants linked to type 2 diabetes, with 11 influencing insulin production and one associated with the X chromosome. This discovery sheds light on the complex pathogenesis of the disease, which affects millions worldwide.
A new study suggests that seeding clouds over the ocean to make them more reflective could actually increase monsoonal rains and cause continents to become wetter on average. This contradicts previous assumptions about the impact of geoengineering schemes on global rainfall patterns.
Researchers reanalyze mitochondrial genome data to reveal new insights into the initial peopling of North America, confirming 15 founding maternal lineages from Beringia. The study's findings suggest that genetic diversity was significantly underestimated in previous estimates.
A new study by endocrinologists at the University at Buffalo has shown that Vietnam veterans exposed to Agent Orange have significantly more Graves' disease, a thyroid disorder. The autoimmune disease was three times more prevalent among veterans who encountered the dioxin-containing chemical.
A survey by Mount Sinai School of Medicine found that 91% of physicians believe 'defensive medicine' is necessary due to malpractice concerns. The study suggests that tort reform can decrease unnecessary testing and rising healthcare costs.
A Kaiser Permanente study found the MMRV vaccine doubles the risk of febrile seizures in 1- to 2-year-old children compared to separate MMR and varicella vaccines. The study analyzed 459,000 children and recommended that families without a preference for MMRV receive separate vaccinations.
A new study by Dr. Fahimeh Ramezani Tehrani predicts the age when women will hit menopause using a simple blood test. The researchers found that the accuracy of the test is high, with an average difference between predicted and actual ages of just a third of a year.
A national study called HEALTHY found that innovative PE programs, healthier food choices, and in-class lessons on healthy lifestyles can benefit children most at-risk for type 2 diabetes. After three years, students in intervention schools had a 21% lower rate of obesity and improved fasting insulin levels compared to comparison schools.
A team of researchers at Boston College has developed a biosensor using carbon nanotubes that can detect minute amounts of proteins with high sensitivity. The sensor can distinguish between different varieties of the same protein and could potentially be used to diagnose diseases such as human papillomavirus.
A report by Queen's University Belfast finds that Northern Ireland's social housing provision is inadequately funded, violating international human rights standards. The report recommends increasing funding for new social housing and tackling land banking practices to address the housing crisis.
Large-scale carbon sequestration could help avoid extreme global warming, but its effectiveness is uncertain due to leakage risks. Geological storage appears more effective in delaying climate consequences with minimal CO2 leakage rates.
Engineered allosteric regulation provides precise control of kinase activity in living cells, enabling scientists to understand cellular processes and dissect the functions of kinases. This new method has exciting applications in basic research and promises to open doors to new scientific insights into cancer and other human diseases.
Research by Duke University scientists reveals that seawater's higher concentrations of mercury make saltwater fish like tuna and shark more toxic to humans. Methylmercury latches onto dissolved organic matter in freshwater, but tightly binds to chloride in seawater, where sunlight can't break it down as easily.
The Elsevier Foundation TWOWS Awards honored twelve talented young women scientists from various regions for their groundbreaking research. The award aims to promote wider participation and excellence in science among developing countries' promising scientists.
Researchers at UCSF have found a link between serotonin, a neurotransmitter, and gestational diabetes, suggesting that high protein diets may trigger the condition. The study's findings offer new insights into possible ways to reverse non-gestational diabetes and provide potential therapeutic solutions.
Researchers identify LGI1 as the main target of autoantibodies in patients with limbic encephalitis, leading to a new diagnostic test and potential therapeutic strategies for other neurological disorders. The findings also suggest that limbic encephalitis should be classified as an autoimmune synaptic encephalopathy.
AcademyHealth recognized leading researchers in health services research and policy, including Dr. Lisa I. Iezzoni and Dr. Aaron S. Kesselheim, for their significant contributions to advancing policy and practice in healthcare.
Researchers discovered that different cells respond differently to stimuli, contradicting previous uniformity assumptions. The study used microfluidics to monitor individual cells' reactions and found nuanced variations in responses.
Researchers at the University of Florida have discovered that grain boundaries in high-temperature ceramic superconductors impede electrical current. The study, published in Nature Physics, provides a theoretical model explaining why these barriers limit the potential of superconductors.
A study found that high HDL levels in women with type 1 diabetes increased the risk of heart disease, while low levels actually decreased risk. The researchers suggest that too much good cholesterol may not always be protective and could even be harmful.
Researchers at TGen discovered a genetic biomarker with significant association to kidney failure in American Indians in Arizona. The study found evidence of some lesser associations between kidney failure and four other markers, all linked to the SUCNR1 gene.
Researchers found that early asymptomatic kidney damage in type 1 diabetes leads to a significant increase in mortality, while normal kidneys offer no increased risk of death. The study involved 658 participants and followed them for 20 years.
The DURATION-2 study found that once-weekly exenatide improved HbA1c levels by 1.5% compared to 0.9% for sitagliptin and 1.2% for pioglitazone, with significant weight loss in the exenatide group. The findings suggest that exenatide should be considered as an adjunct to metformin for improving glucose control and weight loss.
Alana Oldham and colleagues found that water stress, due to gravity's effect on the water column, drives leaf anatomy and morphology in redwoods. This reduces photosynthesis in the upper canopy, but increases water-stress tolerance traits below.
A new study found that vitamin C and E supplements do not prevent pre-eclampsia in pregnant women with type 1 diabetes, but may benefit those with low antioxidant status. The supplement did not cause harm to mothers or babies.
A study by the University of Pittsburgh Graduate School of Public Health found that consuming higher amounts of omega-3 fatty acids does not lower heart disease risk in women with type 1 diabetes. Men with the same condition had a lower rate of heart disease at higher omega-3 intake levels.
Scientists are developing a database of human emotion and behavior by collecting digital representations from actors. The USC CreativeIT Database will help predict patterns in human behavior, leading to potential applications in addiction treatment, customer care, and global security.
Researchers found that shorter pulse lengths produce fewer higher charge states in nitrogen molecules, reducing damage. This phenomenon, known as frustrated absorption, prevents outer valence electrons from being stripped, safeguarding molecule integrity.
Researchers found that eliminating soot pollution from diesel engines and coal sources would provide the world with an additional eight years to reduce carbon dioxide emissions. This study aimed to standardize estimates of soot's contribution to global warming, emphasizing the need for further research.
Researchers found that resveratrol inhibits formation of damaging blood vessels in the eye, a potential preventive therapy for blinding diseases. The compound's novel pathway could become a new target for therapies for eye disease and other problems related to abnormal angiogenesis.
Celia's well-defined eye is visible in NASA's infrared image, measuring 15-20 nautical miles wide. High cloud tops indicate strong thunderstorms, while warm sea surface temperatures support the storm's development.