Researchers at the University of Cincinnati found that ghrelin, a hunger-signaling hormone, regulates cholesterol levels in the brain. Increased ghrelin levels caused mice to develop higher blood-circulating cholesterol, suggesting a potential 'remote control' mechanism.
A new experimental drug targeting the Hedgehog pathway has shown early signs of efficacy in pediatric brain tumor patients, with some still on treatment a year after diagnosis. The study's findings have given the green light for larger Phase II studies to advance targeted therapies against medulloblastomas.
A new treatment regimen combining bevacizumab with standard chemotherapy significantly extends progression-free survival for women with advanced ovarian cancer, reducing disease worsening to 14.1 months compared to 10.3 months. The trial results also point to the possibility of more personalized and effective treatment in the future.
Brown University researchers have gained new insights into graphene defects through molecular dynamic simulations. They found that oxygen atoms forming double bonds with carbon create irregular holes in the lattice. The team proposes adding hydrogen to remove impurities and heal the holes.
Chester A. Mathis receives SNM's 2010 Aebersold Award for his groundbreaking work on early detection in Alzheimer's disease using positron emission tomography (PET) imaging techniques. This recognition acknowledges the significant contributions of Dr. Mathis to advancing molecular imaging and nuclear medicine.
Bengt Roland Långström, a professor at Uppsala University in Sweden, has been recognized for his work in nuclear medicine. He is being honored with the Georg Charles de Hevesy Nuclear Pioneer Award for his over 20 years of experience in synthesizing and applying radiolabeled tracers for PET.
Researchers found that viruses invading the human genome millions of years ago have changed gene regulation in human embryonic stem cells. The discovery provides definitive proof of a theory proposed by Barbara McClintock and has significant implications for regenerative medicine.
Researchers have discovered variations in 10 genes associated with immune response in people with vitiligo, pointing to multiple cellular pathways contributing to the disease. The findings offer potential starting points for developing therapies tailored to individual genetic susceptibilities.