Dr. James Bogenberger has been awarded a 3-year fellowship to research acute myeloid leukemia at TGen, with the goal of identifying therapeutic targets that sensitize AML to epigenetic therapies. The fellowship project aims to translate state-of-the-art biomedical research into novel targeted therapy approaches for leukemia patients.
Researchers found that biological differences between men and women can impact vaccine efficacy, with women typically generating a more robust protective immune response. This knowledge could inform strategies for optimizing vaccination programs, including the timing and dose of vaccines.
Four researchers from the Center for Vaccine Awareness and Research at Texas Children's Hospital presented studies on vaccine attitudes, rotavirus prevention, pertussis cocooning, and school-based immunization programs. The research aimed to educate parents about immunizations and promote healthier children and families.
Bruno Sinopoli, an assistant professor at Carnegie Mellon University, has received a $400,000 grant to investigate tools and methodologies for designing and analyzing cyber-physical systems. His goal is to set new standards for the robustness and security of critical infrastructures such as power grids and transportation systems.
Scientists have discovered that a molecular switch in spider silk controls fiber assembly, enabling the creation of highly stable and elastic fibers. The breakthrough opens the way towards biomimetic production of ultra-strong fibers with applications in various industries.
Researchers have created autonomous molecular 'robots' made of DNA that can be programmed to follow a track, start, move, turn and stop. The development could lead to molecular systems used in medical therapeutic devices and reconfigurable robots.
Archaeologists Alice V. M. Samson and Bridget M. Waller argue that the bared-teeth motif, commonly linked to death and aggression, actually represents social affiliation and benign intent in pre-Columbian Caribbean cultures.
A Brandeis biochemist confirms Darwin's theory of universal common ancestry using a large-scale, quantitative test. The study finds that all life forms share a genetic heritage from single-celled microorganisms to humans, supporting UCA millions of times over alternative theories.
Researchers found significant patterns in discarded brain wave data, revealing connections between low-frequency and high-frequency brain waves. These connections suggest important aspects of brain architecture and function, potentially shedding light on the brain's organizational structure.
Researchers at NYU and Nanjing University have created a DNA-based assembly line that can efficiently produce novel materials on the nanoscale. The system uses three components: DNA origami, programmable cargo-donating devices, and a DNA walker, allowing for precise control over material creation.
Researchers at the University of North Carolina have developed a male contraceptive method using therapeutic ultrasound, which has shown promising results in animal studies. The method involves 15 minutes of ultrasound treatment for six months of contraception, with permanent sterilization achieved with no vasectomy needed.
A study at National Jewish Health found that art therapy significantly improves problem-solving, communication, quality-of-life, anxiety, and self-concept scores in children with chronic asthma. The benefits persisted for six months after treatment stopped, suggesting art therapy as a valuable adjunct to traditional treatments.
A University of Illinois study reveals that breast milk induces unique genetic pathways in infants, differing from those in formula-fed babies. The discovery sheds light on the immune-protective components of breast milk and its role in intestinal development.
A study by LSU researchers found that socioeconomic and physical disadvantages, as well as social isolation, are associated with higher rates of older adult malnutrition death rates across the US. The research highlights the importance of addressing poverty, disability, and limited access to resources in reducing malnutrition-related d...
Researchers have found that biofuel combustion is more complex than previously thought, with diverse chemical reaction networks and the formation of toxic emissions. The study used a combination of laser spectroscopy, mass spectrometry, and flame chemistry modeling to explore decomposition and oxidation mechanisms.
Research at University of California, Riverside found that juvenile male crickets exposed to loud songs from adult males grow larger and invest more in testes. Meanwhile, those without exposure are more likely to act as 'satellites' hanging around singing males to intercept females.
Antipsychotic drugs increase Akt signaling in C. elegans, a common effect across major categories of schizophrenia medication. This finding highlights the importance of Akt signaling in schizophrenia and suggests that medications or dietary approaches targeting this pathway may help alleviate symptoms.
Researchers have developed a tiny silicon chip that can detect specific chemicals and map their location, potentially alerting emergency responders to hazardous situations. The sensor works by manipulating the shape of pores on the silicon flake to respond to specific chemical traits.
David Hanneke's research created a building block of quantum computing, performing what some call the most accurate experiment in science. He will receive the Michelson Postdoctoral Prize at Case Western Reserve University.
Onur Mutlu received a five-year grant to research techniques and algorithms for creating scalable high-performance memory systems. His goal is to develop predictable and controllable systems with guaranteed service quality on multi-core processors.
Researchers discovered a strong link between childhood sexual or emotional abuse and the severity of binge eating disorder. The study found that learned self-criticism and body dissatisfaction are key factors in this association.
Vitamin A supplementation before, during, and after pregnancy significantly improved lung function in preadolescent children. Children whose mothers received vitamin A had a greater forced expiratory volume and vital capacity compared to those who received beta-carotene or placebo.
Researchers evaluated MARS treatment's cost-utility and health-related quality of life in 90 ALF patients. The study found improved HRQoL and reduced healthcare costs after MARS treatment, indicating a potential cost-effective option for ALF patients.
A new study by Michigan State University researchers highlights the need for culturally competent health-care providers and information dissemination about treatment options. The study found that minorities are less likely to consider combining medication and counseling for their children due to barriers such as financial hurdles and l...
Research published in Archives of Disease in Childhood found that giving infants a small amount of sucrose or glucose before immunization significantly reduced crying and pain. Healthcare professionals are recommended to consider using these solutions as an analgesic during painful procedures.
A new method for effective discussions involves a student facilitator who directs the discussion, rather than a leader controlling content. This approach encourages all participants to contribute, promoting equal participation and improving communication skills.
A study published in the Journal of Political Economy suggests that government regulation of nurses' pay leads to higher death rates in U.K. hospitals. The research found a significant association between regulated wages and increased heart attack death rates.
Dr. Patrick Sullivan is leading a research project to identify genetic links to psychosis in schizophrenia and bipolar disorder. He will analyze DNA from four families with a high number of affected members to uncover rare genetic variants and compare them to unrelated samples.
Three CU-Boulder-built biomedical payload devices will study microbial biofilms in space, aiming to improve astronaut health and understand gene and protein changes in pathogens. The experiments, led by Rensselaer Polytechnic Institute, will examine microbe growth and interactions in space vs. normal gravity.
Researchers found that anti-inflammatory drugs can preserve kidney function in hypertensive rats by regulating blood pressure on tiny filters called glomeruli. The study aims to understand how kidneys autoregulate pressure and explore the role of inflammatory factors in arteriole dysregulation.
A new study from the Regenstrief Institute provides a framework for evaluating the costs, effort, and value of health information exchange services. The framework will help track the development and utilization of these services, crucial for understanding their impact on quality of care and patient safety.
A GSU professor's research reveals a strong connection between children participating in federal school nutrition programs and an increased likelihood of becoming overweight. The study suggests that preventing childhood obesity is crucial to reducing the risk of obesity in adulthood.
Matthew Lux, a Virginia Tech Ph.D. student, has been awarded a US Department of Defense SMART scholarship to explore opportunities in synthetic biology for defense applications. His research involves developing intelligent sensors and countermeasures using calibrated genetic parts.
Physicists at McGill University have developed a cantilever force sensor to measure the energy involved in adding electrons to semi-conductor nanocrystals. This innovation could lead to the development of components replacing silicon chips in computers, increasing speed and reducing size.
University of Missouri researcher Jason Grissom is leading a study to determine the qualities and skills necessary for effective school principals. The study, funded by a $1 million grant, aims to gather data from K-12 administrators, teachers, and district officials to examine what makes a principal successful.
A University of Alberta study found that people living in neighborhoods with high perceived traffic density were more likely to have a higher Body Mass Index (BMI) than those who didn't. The study also revealed age and socioeconomic status as significant factors, with younger individuals experiencing greater BMI increases.
A new study by Stanford researchers highlights the need for standardized criteria in diagnosing food allergies due to differing definitions and inconsistent treatment approaches. This could lead to misdiagnosis and unnecessary anxiety for patients with food intolerance, while also potentially overdiagnosing food allergies.
Researchers at UT Southwestern Medical Center have identified a genetic sensing mechanism that allows E. coli to form colonies in cattle, and found that interfering with this system can prevent the bacteria from colonizing and reaching humans. This discovery could lead to new strategies for preventing food-borne illnesses.
Mediterranean red coral populations thrive in three decades-old Marine Protected Areas, but future conservation efforts may be needed to ensure species resilience. The areas have proven effective in conserving this slow-growing species.
A consistent pattern in five genes has been found to predict the likelihood of relapse in pediatric T-cell acute lymphoblastic leukemia (T-ALL), allowing for more aggressive treatment to be administered from diagnosis. This discovery has significant potential to improve outcomes for patients at high risk of relapse.
Scientists studied Mycobacterium tuberculosis proteasome structure and assembly to understand its role in pathogen survival. This knowledge could aid in developing anti-TB drugs by preventing proteasome maturation.
Researchers link PMSE syndrome to mTOR pathway, a complex network implicated in common neurological disorders with autism-like symptoms. The study reveals clues about TSC, a relatively common disorder, and its connection to PMSE and other neurological conditions.
Long-necked dinosaurs were able to grow extremely long necks due to their unique digestive system, which allowed them to chew and digest food more efficiently. This enabled them to browse their surroundings without having to move their large body weight.
Researchers at the University of Sheffield created a unique map showing General Election results based on population data. The map provides an alternative perspective by reflecting where people live in the country, enabling a better understanding of voting preferences and population density.
Researchers discovered a specific mutation that promotes fibril development, leading to organ damage and death. The study suggests this finding could be a target for future drug development in treating the fatal condition.
Researchers at Mahidol University have created a rapid prenatal test for diagnosing alpha-thalassemia. The new assay boasts high sensitivity and specificity, as well as a decreased risk of contamination, making it suitable for large-scale screening in Southeast Asia.
A new Cochrane Systematic Review suggests phakic intraocular lenses (IOLs) may be a safer alternative to excimer laser surgery for moderate to high levels of short-sightedness. Patients who underwent IOL treatment reported better spectacle-corrected vision and contrast sensitivity, as well as higher patient satisfaction.
Researchers from the University of Central Florida used LiDAR technology to map the ancient Maya city of Caracol, detecting over 11,000 new structures and confirming its size. The technology revealed extensive agricultural terracing, showing the Maya were adept at 'building green' long before modern terminology.
A recent study by London School of Hygiene & Tropical Medicine found that British Indian children have substantially lower rates of mental health disorders, with only 3.7% affected compared to 10.0% for White children. This advantage was attributed to factors such as two-parent households and higher academic abilities, suggesting a rea...
Researchers have developed a new type of drug that targets the BCL6 protein, which is essential for lymphoma cell survival and multiplication. The breakthrough could lead to improved treatment options with fewer side effects, increasing cure rates for diffuse large B cell lymphomas.
A rare opportunity to study how a critically endangered species copes with an earthquake- induced tsunami has been provided by researchers. The Devils Hole pupfish inhabit a small, shallow pool in the Mojave Desert, and the quake's impact on their habitat and behavior was documented on camera.
Preventable infectious diseases are the leading causes of child mortality worldwide. According to a new study published by The Lancet, these diseases are responsible for two-thirds of nearly 9 million child deaths globally in 2008. The analysis reveals that global efforts must be targeted to have maximum impact.
Researchers at Linköping University discovered a new function that regulates stem cell production of different types of cells in various parts of the nervous system. The study found that Hox genes, similar to a GPS system, guide stem cells to produce specific nerve cells in certain regions.
The surveys will track trends in behavioral health services, consumer access, and cost sharing in the nation's privately insured individuals. The data collected will provide insights for policy-makers, advocacy groups, and health plan executives on how to improve delivery of behavioral health services.
Exercise programs improved anxiety and depression symptoms in individuals with schizophrenia, while changes in physical health outcomes were not significant. Regular exercise is recommended for those with schizophrenia, just like the general population.
Adults with sickle cell anemia exhibit lower average nonverbal function scores, as well as difficulties in processing speed, working memory, and executive function. Anemia is associated with neurocognitive impairment in older patients, highlighting the need for early identification and intervention.
Researchers found that African American women are more aware of the importance of screening and are more willing to undergo the procedure, while men report barriers such as lack of trust in the healthcare system and fear of the procedure. Despite these differences, both groups recognize the benefits of early detection and prevention.
A Carnegie Mellon study analyzed over a billion Twitter messages to gauge public opinion on consumer confidence and presidential job approval. The results showed correlations between Twitter-derived sentiment measurements and traditional polling data, with notable similarities in trends and fluctuations.
Researchers have discovered high-activity mutants of human butyrylcholinesterase that could be used to develop anti-cocaine medication. Additionally, a microbiocide-based HIV prevention measure holds promise for developing countries, particularly in sub-Saharan Africa.
Researchers create powerful new tool for calculating Casimir forces, allowing repulsion in microelectromechanical systems. This breakthrough could significantly reduce the failure rate of existing MEMS devices and enable affordable, new technologies.