A NYU nursing-dental research team discovered that oral blood samples drawn from deep pockets of periodontal inflammation can measure hemoglobin A1c, a key indicator of diabetes status. The study found minimal false positive and negative results, making it a promising alternative to finger-stick samples.
A study by Universidad Carlos III de Madrid's Computer Science Department investigates emotions' importance in software engineering, focusing on requirements engineering. The researchers applied a social psychology tool, the affect grid, to discover that emotions impact requirements development and user experience.
Researchers identified 22,688 RNA editing events, with most converting adenosine to inosine. The study suggests a potential connection between RNA editing and miRNA-mediated regulation.
Two proteins, Rif1 and Rif2, discovered to deactivate DNA repair surveillance system, preventing cell 'anti-enzyme shield' from malfunctioning. Telomeres provide molecular 'caps' protecting chromosome ends from accidental breaks.
Researchers found that big fish in coral reefs prefer sheltering under large, flat table corals due to their importance as a source of cover. The team's study suggests that maintaining these structures could be crucial for the reef's resilience to climate change.
A Viewpoint published in The Lancet disputes reports of NHS decline in productivity. Quality improvement was found to be significantly higher than initially thought, with notable gains in areas like critical care and patient experiences. This challenges the narrative of declining healthcare productivity in England.
A team of researchers has discovered how the protein SAMHD1 protects immune cells from HIV by starving the virus of necessary building blocks. This finding could lead to more effective anti-HIV drugs and new insights into other viral infections.
The article provides IPM program recommendations for managing the southern pine beetle, a chronic insect pest in southeastern US pine forests. The beetle has three population phases, and an IPM program should be tailored to each phase, with prevention and restoration being primary concerns during the latent phase.
Researchers have discovered that dynein, a motor protein, plays a crucial role in spindle alignment during mitosis. A signal from the chromosomes involving the ras-related nuclear protein (Ran) blocks LGN and dynein from attaching to the cell cortex closest to the chromosomes.
Researchers have discovered a mechanism by which the immune system tries to halt HIV's spread, focusing on a protein called SAMHD1 that protects cells from viral hijacking. By understanding this mechanism, scientists may find new ways to stop or slow the virus' ability to infect.
A study published by the American Academy of Neurology suggests that consuming excessive calories may double the risk of mild cognitive impairment (MCI) in individuals aged 70 and above. The findings indicate a dose-response pattern where higher caloric intake corresponds to increased MCI risk.
A new MRI technique allows for non-invasive examination of battery internal workings, enabling testing of various designs and materials under normal operating conditions. This method has the potential to improve battery performance and safety by visualizing build-up of lithium metal deposits on electrodes.
Harvard researchers uncover how halofuginone, a compound derived from an ancient Chinese herb, regulates autoimmunity and inflammation by triggering a stress-response pathway. The discovery provides new insights into the physiological regulation of the immune system and novel therapeutic approaches for autoimmune disorders.
Researchers found that despite high success rates of ACL surgery, many amateur football players struggle to return to play due to fear of re-injury and decreased performance concerns. The study suggests that additional research is needed to analyze the rate of return based on position played.
Epidural steroid injections showed promise as a treatment option for athletes suffering from lumbar disc herniations. The 89% success rate allows patients to participate in physical therapy sooner and reduces time missed from play. However, certain injuries still require surgery and long-term recovery.
The study found that primary Anterior Cruciate Ligament reconstruction improves quality of life and sports functionality for athletes. Researchers also identified risk factors, including younger female soccer players, smokers, and patients with meniscal or chondral injury at the time of surgery.
Researchers found that children treated more than 150 days after an ACL injury have a higher rate of other knee injuries, including medial meniscal tears. Weight over 143 lbs was also associated with an increased risk of meniscal tears at the time of surgery.
Researchers found that short therapy with Pioglitazone can prevent the long-term effects of maternal obesity on offspring. The study shows a potential role for drugs activating peroxisome proliferator-activated receptors in preventing metabolic syndrome in adult offspring of obese mothers.
A study by the American Orthopaedic Society for Sports Medicine found that athletes wearing properly fitted helmets were 82% less likely to experience loss of consciousness due to concussions. Helmet fit was not associated with a significant impact on concussion severity, but proper air bladder inflation was.
A new study by researchers at the American Orthopaedic Society for Sports Medicine found that elbow position alone does not affect injury rates or performance in baseball pitchers. Instead, visual elbow drag was positively associated with ball velocity, suggesting that proper pitching technique is crucial for optimal performance.
Researchers found PRP treatment to be effective in treating partial UCL tears, improving KJOC Score and DASH Score. Athletes returned to play on average 10 weeks after treatment.
A recent study found that approximately 73% of healthy individuals have abnormal MRI scan results, highlighting the limitations of imaging in hip pain diagnosis. The study emphasizes the importance of correlating clinical signs and symptoms with imaging findings for accurate treatment decision-making.
Researchers investigated whether high levels of cell-free fetal DNA in the first trimester predict preeclampsia. No significant difference was found between women with and without the condition.
Researchers at Lawrence Livermore National Laboratory found a phase change in molten magnesium silicate that transforms to a more dense liquid with increasing pressure. This discovery provides insight into planet formation and suggests that extra-solar 'Super-Earth' planets may have different structures than Earth.
NASA's Terra satellite captures visible image of Cyclone Giovanna on February 10, revealing high thunderstorms around its center. Forecasters predict landfall in east-central Madagascar with heavy flooding, rough surf conditions, and strong winds.
Researchers at Ruhr-University Bochum found that enzymes are only imported into peroxisomes when their transport proteins are recycled. This discovery supports the export-driven-import model and sheds light on the complex process of protein import.
More than 4.5 million Americans are living with a total knee replacement, with osteoarthritis being the leading cause. The prevalence of TKR is higher in women, with 5.3% compared to 4.1% in men.
Research finds that elective delivery at 39 weeks is associated with lower rates of composite adverse neonatal outcomes compared to deliveries at earlier or later gestational ages. Continued pregnancy beyond 39 weeks also tends to have better maternal outcomes, although differences are only significant at 37 weeks.
A Simon Fraser University graduate student project, Sonic Cradle, uses breathing sounds to shape musical patterns in a dark chamber, promoting relaxation and inner peace. The technology has the potential to provide psychological benefits without over-stimulation.
A study by the Society for Maternal-Fetal Medicine found that women who deliver or intend to deliver outside of hospitals have a lower risk of obstetric intervention. However, newborns intended for home births are at a higher risk of neonatal seizures compared to hospital births.
Infants with birth defects delivered at night or over the weekend fared just as well as those delivered on a weekday, according to a new study. The finding is good news for all parties and suggests that delivery timing shouldn't be based on day of the week.
Cyclone Jasmine has maintained Category One hurricane status with maximum sustained winds near 75 knots (86 mph), and its eye is now about 60 nautical miles in diameter. The storm is moving southeast at 8 knots (9 mph) through an area of stable air, weakening the warm tropical cyclone.
Scientists at the University of Missouri will use the donation to create the Sidney Kimmel Institute for Nuclear Renaissance, studying fundamental physics of unknown energy producing reactions. The goal is to discover a new, clean alternative form of energy with potential uses depending on the extracted energy and process consistency.
A new study suggests that preterm labor diagnostic markers are not universal, and should be tailored to each individual's risk factors. The research found distinct inflammatory mediators in response to different bacterial pathogens, highlighting the need for personalized approaches to diagnosis and intervention.
Researchers found that red blood cell transfusion decreased physical fatigue in women with acute postpartum anemia, but the effect was small. The study, which included over 50 Dutch hospitals, showed that expectant management without transfusion is a preferred approach.
The department's second annual analysis of orthopaedic procedures reveals focus areas such as VTE prevention, MRSA control, and reducing readmission rates. NYU Langone Medical Center aims to embed quality and patient safety in every aspect of its work.
Researchers create comprehensive 3-D map of earthquake zone using LiDAR technology, revealing details of fault ruptures and deformation. The study provides insights into how earthquakes change the landscape, shedding light on minor faults that contribute to major earthquakes.
A study published by the NIH shows that Kineret therapy is effective in stopping the progression of organ damage in people with neonatal-onset multisystem inflammatory disease (NOMID). By preventing organ inflammation, scientists were able to preserve organ function in most patients.
A mathematical model predicts and explains the emergence of burst suppression, a low-activity state in response to reduced cellular energy. The study suggests that burst suppression may be used to guide induced coma and track recovery from brain injuries, offering new insights into brain neurochemistry and neurophysiology.
A new study examines how numerate individuals process information differently, leading to more informed decisions. People who are numerate are less influenced by other information and see numbers as abstract symbols, allowing them to make better choices.
Scientists at the University of Alberta have shed light on the structure and function of PNKP, a key DNA repair enzyme. By understanding how this enzyme repairs damaged DNA, researchers hope to develop new therapies that target cancer cells while leaving healthy cells intact.
Researchers at Thomas Jefferson University found that intraarticular delivery of local analgesic bupivacaine reduces postoperative pain and narcotic consumption, while minimizing complications. The study suggests a potential new option for better pain management following knee replacement surgery.
Researchers discovered that osteoarthritic knee joints have a constant state of repair, while hip joints do not. This suggests different treatment strategies may be needed for knee and hip osteoarthritis. A biomarker was identified to measure joint degeneration and repair response.
A new study found that weight gain and dietary changes are not effective in preventing repeat preterm birth. Women who have had a prior preterm birth should follow standard weight gain guidelines during their second pregnancy to minimize risk.
Researchers report successful early transplantation of human placenta-derived mesenchymal stem cells into neonatal rats with birth-related brain damage, detecting neurologic improvement.
A study published in Cell reveals that only a handful of genes and proteins guide the growth of motor neurons, which eventually connect with muscles. This discovery may lead to new therapies for ALS and provide insight into certain cancers.
Researchers analyzed metal-on-metal hip replacement studies for negative outcomes, finding no bias in results from authors with disclosed conflicts. Despite a trend towards increasingly negative study results over time, the findings support the AAOS's disclosure requirements and peer review process.
Researchers at Northwestern University have developed a new method for creating scaffolds that are more flexible and less time-intensive than current technology. The process uses ceramic nanoparticles and elastic polymers to create highly interconnected pores that do not require the use of salt.
Manan Mehta developed a method to create circularly permuted proteins, which are useful for studying molecular evolution and designing biosensors. The new technique uses transposase engineering to create diverse protein variants with great control.
A Yale University study found that C-section deliveries before 34 weeks of pregnancy for small-for-gestational-age babies are associated with higher odds of developing respiratory distress syndrome. The researchers analyzed data from 2,885 preterm babies and found a significant link between C-sections and breathing problems.
Researchers at the University of Cambridge have discovered that iron pyrite, commonly known as 'Fool's Gold', has catalytic properties. The study focused on the reactions between iron pyrite and nitrogen oxides, an extremely poisonous class of compounds produced by car engines and industrial power plants.
Researchers analyzed tumor specimens from 19 advanced stage carcinoma patients, discovering changes in biomarker expression that may impact therapy selection for women with recurrent ovarian cancer. The study highlights the importance of analyzing current tumor tissue to make informed treatment decisions.
Children with obstructive sleep apnea showed significant improvements in attention deficits, daytime sleepiness, and behavioral problems after treatment with positive airway pressure (PAP) therapy. The study found benefits even when children only used PAP for a few hours a night.
A study presented at the Society for Maternal-Fetal Medicine's annual meeting demonstrated that massively parallel sequencing of maternal plasma DNA can detect all three most prevalent fetal aneuploidies. The test showed 100% sensitivity and specificity for trisomy 21 (Down syndrome) and high accuracy for other autosomal aneuploidies.
Researchers have found that cochlear implants can restore hearing in organ transplant patients without significant health risks. The study suggests that patients who wait at least six months after the transplant and take the right antibiotic before and after the procedure can achieve successful outcomes.
A recent study published in the Journal of Autism and Developmental Disorders found a joint association between maternal and paternal age and autism risk. Mothers with autistic children were on average 6.5 years older than non-autistic women, while fathers had an average age difference of 5.9 years.
Researchers at Thomas Jefferson University found that curcumin suppresses nuclear receptor activators, which can bypass androgen deprivation therapy. Curcumin also reduced cell number and inhibited survival in prostate cancer cells, with similar results seen in mice studies.
The American Academy of Orthopaedic Surgeons has established a new credentialing process for doctors who plan to travel internationally to disaster sites. The Disaster Responders Certification Program provides training and certification for orthopaedic surgeons, with three levels of certification available. A study reports long-term po...
New York University researchers have discovered that top-heavy structures can hover stably in the air due to aerodynamic forces. The findings suggest a new approach to designing stable flapping-wing aircraft and robots.
A new study published by the American Thoracic Society found that PAP therapy significantly improves neurobehavioral function in children with obstructive sleep apnea syndrome. Despite suboptimal adherence, patients showed improvements in attention deficits, behavior, and quality of life.