Researchers at Cornell University have engineered E. coli bacteria to produce glycoproteins for pharmaceuticals, reducing production time and cost. The method, called 'glycans by design,' uses enzymes to tailor sugar structures, leading to the development of cheaper and faster pharmaceuticals.
Researchers have identified a new protein, S100PBP, that suppresses cathepsin Z and reduces pancreatic cancer cells' ability to attach to other tissues. This discovery may lead to the development of novel preventive and therapeutic targets for pancreatic cancer.
Scientists have developed a new technology to purify natural gas by removing carbon dioxide, which increases the energy density and efficiency of storage and transportation. The 'super natural gas' burns hotter and occupies less space than traditional fuel.
A study found that antipsychotic medication is associated with a modest and time-limited increased risk of heart attack among older patients treated for dementia. The risk was highest at the beginning of treatment, decreasing after the first month.
A new study reveals that short-track speed skaters' brains undergo significant structural adaptations in response to training, particularly in the right hemisphere of the cerebellum. This results in enhanced balance and coordination abilities, essential for high-speed cornering and passing on ice.
A Purdue University scientist has developed a way to encase nutritional supplements in food-based products, protecting them from degradation due to heat, light, oxygen, and other external factors. The method involves creating crystalline-like fibers that embed the nutraceuticals, allowing for improved stability and bioavailability.
A study found that seven out of eight people who contacted a telenurse helpline followed their self-care advice, with satisfaction and confidence playing key roles. The researchers believe this confirms nurse triage helplines as a cost-effective method for addressing self-care needs.
Three new studies explore the use of proven interventional radiology treatments to help individuals with morbid obesity. One treatment targets ghrelin, a hunger hormone, while another uses X-ray visible embolic beads to block stomach arteries. A third study uses stem cells to repair degenerated discs and reduce pain. These minimally in...
Researchers at Tel Aviv University create gold nanoparticles that trigger an immune response when coated with specific chemical residues, revealing a key link between hydrophobicity and immune system activation. This breakthrough has the potential to improve drug delivery systems and lead to more effective medications and vaccinations.
A University of Oregon sociologist warns that cultural inertia is hindering efforts to address climate change. She argues that serious discussions about solutions are mired in societal resistance to change, which must be recognized and addressed at all levels.
Researchers have developed a nanoscale sensor that can electronically read the sequence of a single DNA molecule, leading to potential breakthroughs in personalized medicine. The technique is fast and inexpensive, making it possible to reveal predispositions for afflictions like cancer, diabetes, or addiction.
Researchers found that aggressive treatment for chronic DVT can restore blood flow and improve quality of life for those with post-thrombotic syndrome. Minimally invasive procedures like angioplasty, stenting, and thrombolytic therapy showed promising technical and clinical outcomes.
A study by ecologists in New Zealand found that a 1170 km2 marine sanctuary significantly improved survival of Hector's dolphins, one of the rarest dolphin species. The research revealed a 5.4% increase in survival rates since the Marine Protected Area was designated in 1988.
Stanford researchers found a disconnect between reported cardiac toxicities in journal articles and FDA labeling for sunitinib, a kidney cancer treatment. The authors argue that the current method of measuring adverse events is inadequate, leading to under-reporting of side effects.
Research suggests that early growth in the womb and first few years of life is positively related to total hip bone size and mineral content. Stronger hips can protect against future hip fractures, leading to optimized early growth strategies to reduce osteoporotic fracture risk.
A new study found that the novel oral anti-coagulant rivaroxaban is as effective as traditional treatment for blocked lung blood vessels, with lower rates of major bleeding. The EINSTEIN-PE trial compared rivaroxaban to standard therapy and demonstrated its non-inferiority in treating pulmonary embolism.
Researchers have developed a 'thermal' approach to invisibility cloaking that isolates or cloaks objects from sources of heat. The method uses transformation optics to control thermal diffusion, allowing for the shielding of areas from heat and the concentration of heat in small volumes.
A structured coaching program called Coaching Boys into Men has been found to improve male high school athletes' ability to recognize and intervene in dating violence. The program, delivered by coaches, increases positive bystander behaviors and encourages athletes to be leaders in their communities.
The American Institute of Ultrasound in Medicine (AIUM) recognized outstanding achievements in medical ultrasound at the 2012 Annual Convention. Awards were presented to individuals who have significantly contributed to the growth and scientific progress of medical ultrasound.
A study of over 200,000 people found that adults who sat for 11 hours or more per day had a 40% increased risk of dying in the next three years. Regular physical activity can still reduce this risk, but avoiding prolonged sitting is also crucial.
Bioorthogonal chemistry allows doctors to administer separate ingredients that combine to produce medicine inside patients' bodies. This emerging field has the potential to revolutionize drug development and diagnosis by enabling targeted treatment of diseases.
Researchers at the University of California, San Diego, found that chronic stress triggers the production and accumulation of insoluble tau protein aggregates inside brain cells, similar to neurofibrillary tangles. This may explain why people prone to stress are more likely to develop sporadic Alzheimer's disease.
Researchers at MIT and Harvard University have developed the 'buckliball,' a hollow spherical object that collapses reversibly when air is sucked out, exhibiting cooperative buckling behavior. This design has the potential for widespread applications in structures, materials, and toys.
A study analyzed Spanish companies' scientific production between 1995 and 2005, revealing that only a few genuinely Spanish companies are most productive, while multinational firms dominate the market. The study highlights the need for increased investment in R+D to close the gap with other developed countries.
Helen Hobbs, UT Southwestern researcher, receives prestigious award for identifying genetic factors that contribute to variations in cholesterol levels. Her work has led to a 28% reduction in LDL cholesterol levels and an 88% reduction in risk of coronary heart disease.
Researchers found that chronic right ventricular pacing significantly reduces survival in ICD patients with left ventricular dysfunction, but biventricular defibrillator devices mitigate this effect. The study suggests that CRT-D therapy may be beneficial for these patients despite high right ventricular pacing requirements.
Dr. Stephanie R. Wilson, MD, will receive the Joseph H. Holmes Clinical Pioneer Award for her significant contributions to the growth and development of diagnostic ultrasound. She is a renowned educator with numerous prestigious teaching awards and has completed over 47 visiting professorships worldwide.
Scientists have developed a new type of plastic that can repair scratches and cuts, changing color to warn of damage and healing itself when exposed to light. This self-healing plastic has potential applications in products such as cell phones, laptops, and cars, offering advantages over traditional plastics
Regenstrief Institute investigator Noll Campbell has been chosen by the American Geriatrics Society to receive a Merck/American Geriatrics Society New Investigator Award. His clinical research on medication effects on older adults aims to improve care for frail populations.
Researchers found that suppressing bacterial communities with antibiotics may actually help treatment-resistant bacteria flourish, leading to more infections. The study suggests new avenues for developing more effective treatments and improving patient outcomes.
University of Cincinnati researchers have developed predictive software to analyze two years' worth of operating data from a commercial wind turbine, identifying key components with high failure rates and average downtime. The study aims to establish real-world performance metrics for turbines, enabling optimal scheduling of maintenanc...
Researchers at Thomas Jefferson University Hospital found carotid artery stenting to be safe and effective in patients over 70, with a low risk of adverse events. The study showed that while the risk increases with age, it remains extremely low even for those aged 85 and above.
A recent study has created motor neurons using skin cells from a patient with inherited MND, discovering abnormalities in protein TDP-43 that lead to motor neuron cell death. This breakthrough model could speed up the discovery of new treatments for the devastating disease.
New research from Brigham and Women's Hospital shows that ticagrelor significantly reduces the time to a second cardiovascular event or death, in addition to reducing total events. The study found that continued use of ticagrelor after a cardiac event is both safe and effective in preventing further cardiac events.
A study published by Cleveland Clinic found that bariatric surgery significantly improved blood sugar control, with 42.6% of gastric bypass patients achieving normal levels without medication. Sleeve gastrectomy also showed promising results, with 36.7% of patients reaching normal blood sugar levels.
Dr. Joshua A. Copel, a renowned expert in maternal and fetal medicine, will receive the William J. Fry Memorial Lecture Award. He has significantly contributed to the scientific progress of medical ultrasound through his innovative research efforts.
Charles C. Church will receive the prestigious award for his 30-year commitment to AIUM and extensive research on high-intensity focused ultrasound therapy, among other notable achievements.
Key indicators of the planet's state include higher carbon dioxide levels, rising air and ocean temperatures, melting sea ice and permafrost, and biodiversity loss. Scientists warn that if trends are not reversed, critical thresholds will be pushed beyond, leading to catastrophic consequences.
Researchers at Queen's University Belfast have developed a biotechnological route to remove and recycle phosphate from wastewater. The team has discovered a physiological 'shock' treatment that significantly increases microbial uptake of phosphorus and its accumulation inside cells.
Researchers found that over 68% of participants failed to take medication daily, with young men who smoke and drink alcohol being the least likely to follow treatment. High rates of hypertension remain steady in the region, contrary to Western Europe's decline.
A dual-chamber pacemaker reduces the relative risk of fainting episodes by 57% in patients with severe asystolic NMS, according to a new study. The treatment is effective in reducing syncopal recurrences in this highly selected population.
A multi-year study by WSU researchers found no significant differences in grape and wine quality due to grafting, with climate and vintage being the dominant factors. The experiment tested six commercial rootstocks against own-rooted vines for three popular varieties.
A recent study found that human noise has indirect effects on plants, benefiting some species like scarlet gilia while harming others like piñon pine. The study's findings suggest that noise can alter pollination patterns and affect seed production, with consequences that may last for decades.
A new study from the University of Leicester found that patient information leaflets for cancer trials are often poorly written, leading to confusion among patients. The research suggests that a standardized approach to writing these leaflets could improve patient understanding and trust in the decision-making process.
Researchers develop a new antimicrobial coating for urinary catheters, reducing bacterial attachment and infection risk. The coating could prolong catheter life, save NHS millions, and minimize patient complications.
Researchers discovered a previously unknown phenomenon in quantum plasmas, enabling positively charged particles to form atom-like structures. This discovery accelerates current conduction, potentially revolutionizing nanotechnology and applications such as micro-chips and semiconductors.
The grant will support research on the relationships between body composition, muscle and bone strength. Dr Edwards' project aims to clarify uncertainties with regard to these relationships and assess their impact on fracture risk.
A meta-analysis of 32,053 patients found warfarin to be effective in preventing strokes and non-central nervous system embolism in patients with nonvalvular atrial fibrillation. However, elderly patients, women, and those with previous stroke or TIA were at higher risk.
A study of 1018 adults found that those who consumed chocolate more frequently had a lower body mass index (BMI) compared to those who ate it less often. The researchers also found a positive association between chocolate consumption and improved metabolic health, including lower blood pressure and insulin sensitivity.
A study found that newly insured and uninsured adults had greater emergency department use than continuously insured adults. Adults with recent changes in health insurance status, particularly those with new Medicaid coverage, were disproportionately likely to use EDs, suggesting reduced access to primary care services.
A new method for mass-producing high-quality graphene nanosheets has been developed by researchers, enabling the production of sheets at a lower cost than current methods. The technique uses dry ice and an industrial process to create flakes of graphite with opened-up edges, making them soluble in solvents and allowing for easy separat...
Scientists have developed a new approach to capturing carbon dioxide from smokestacks using nitrogen-based ionic liquids. The technology avoids pitfalls of current methods by being odorless, non-evaporative and easily recyclable.
A new study published in the New England Journal of Medicine reveals that highly detailed CT scans can safely and quickly rule out heart attacks among many patients with chest pain. The study found that patients with negative CT scans can be discharged from the hospital within hours, reducing costs and emergency room crowding.
A University of California, Riverside professor and researchers developed a model that uses Twitter data to predict traded volume and value of a stock the following day. The model outperformed other investment strategies by between 1.4 percent and nearly 11 percent.
Severe ill health has been found in bottlenose dolphins in Barataria Bay, Louisiana, which received heavy exposure to oil during the Deepwater Horizon spill. Preliminary results show underweight, anemic and diseased dolphins, as well as low levels of stress response hormones.
Autism Speaks has awarded $1.1 million in funding to support research projects focusing on differences between DSM-IV and proposed DSM-5 diagnostic criteria, the impact of flame retardants on immune systems, and strategies to improve quality of life for individuals with autism.
A new study from the University of Cincinnati found that children exposed to high levels of secondhand smoke who also had allergic sensitizations during early childhood are at greater risk for decreased lung function. Lung function among girls was six times worse than in boys who were exposed to similar levels of both secondhand smoke ...
Researchers found that butterfly wings' 'art of blackness' can boost the production of green fuels by doubling the hydrogen gas produced from water and sunlight. The team created computer models to confirm this filtering effect, which allows shorter wavelengths of light to reach a membrane below the scales.
New research shows that lowering LDL cholesterol beginning early in life can lead to a significant reduction in the risk of coronary heart disease. The study found that a consistent 50-60% reduction in CHD risk was associated with each 1 mmol/L lower lifetime exposure to LDL cholesterol.
International experts agree on the need to better understand biodiversity loss and its impact on ecosystem services, which are crucial for human well-being. The new framework sets out a strategy to address biodiversity-related research efforts and inform policy decisions.