The Brazilian Ministry of Health, Oswaldo Cruz Foundation (FIOCRUZ), and Drugs for Neglected Diseases initiative (DNDi) Latin America have partnered to develop new therapies and diagnostics for neglected diseases. This partnership aims to boost innovation in the field and provide new health tools to Brazil's public health programs.
A recent study reveals that basal-like breast tumors and ovarian tumors have similar genetic origins, suggesting potential for shared treatments. The research found unique genetic signatures within each subtype, highlighting the need for personalized cancer therapies.
Researchers found that constraining world trade is unlikely to help combat climate change, as emissions mainly originate from the production process of imported goods. The US current account deficit and China's energy mix are significant contributors to CO2 transfers.
Mayo Clinic researchers have developed an efficient editing toolkit for customizing zebrafish genomes, eliminating a bottleneck in biomedical research. This breakthrough enables targeted genetic modifications for studying human diseases, including modeling point mutations and regulating gene expression.
A University of Utah study found that periodic changes in winds 15 to 30 miles high in the stratosphere influence deep-sea circulation patterns, affecting Earth's climate. The research revealed the North Atlantic as a sensitive area where warming or cooling from the troposphere can trigger downwelling events.
A study of 200 major international water-related projects identified existing and emerging challenges, including insufficient management, urbanization, and climate change. Investing in science and strengthening the science-policy interface can help reduce risks and inform decision-making.
Scientists at Scripps Research Institute developed a new technique to synthesize complex terpenes, a crucial step towards cheaper and fully synthetic cancer drugs like Taxol. The breakthrough mimics a natural biochemical phenomenon that allows cells to make these compounds, overcoming significant challenges in organic chemistry.
The European Society for Medical Oncology (ESMO) has awarded 16 new centers with integrated oncology and palliative care accreditation. A new study from Italy highlights the underuse of adjuvant analgesics in cancer pain management, emphasizing close patient follow-up.
Scientists found evidence that early microbes colonized land 2.75 billion years ago, producing oxygen and weathering minerals. This discovery challenges the long-held assumption that life was limited to oceans during this period, suggesting a more significant role for microorganisms on land.
Researchers at Duke University Medical Center discovered a molecule necessary for producing nylon using genetic changes found in cancer tumors. This breakthrough enables environmentally friendly adipic acid production from cheap sugars.
A UC San Diego study has identified a human gene called Human Schlafen 11 that produces a protein blocking the replication of HIV in infected cells. The research may lead to diagnostic tests and therapeutic drugs to prevent AIDS progression.
A study by NIH/National Cancer Institute reveals shared genomic features between high-grade serous ovarian cancer and one subtype of breast cancer. This similarity suggests that the two cancers share a common molecular origin, facilitating comparison of therapeutic data.
Researchers at Harvard University have successfully controlled the behavior of worms by manipulating their neurons with precise laser beams. By hijacking key neurons, they can instruct the worm to perform specific actions, such as turning in a desired direction or responding to fake sensory inputs.
A new study finds that climate change could lead to significant changes in Pacific ecosystem distribution, affecting thousands of marine animals and coastal communities. Some species, like loggerhead turtles and sharks, may face harsh impacts, while others, such as seabirds and tunas, may benefit from shifting habitats.
Researchers at MDC Berlin-Buch identified subpopulations of B cells with activated Myc genes, essential for germinal center formation and maintenance. These findings shed light on the origin of B-cell lymphomas derived from germinal centers.
A team of researchers identified genetic causes of the most common form of breast cancer, Estrogen-Receptor positive Luminal A subtype, providing clues for new therapeutic targets. They also found a molecular similarity between basal-like breast cancers and high-grade serous ovarian tumors.