A University of Florida study has identified a protein called TRIP-Br2 that helps regulate fat storage and release in cells. When absent, this protein enables mice to burn fat and resist obesity, even on high-fat diets.
A team of researchers at the University of Pennsylvania School of Medicine discovered that metformin suppresses glucagon's ability to generate a signaling molecule, pointing to new drug targets. This finding could lead to improved diabetes treatments with reduced side effects.
Researchers solved the structure of α-catenin, a protein crucial for cell binding and tissue formation. The discovery reveals how α-catenin interacts with the cytoskeleton and cadherins to stabilize adhesion complexes.
Ultrastable glasses have been produced in days or hours with properties matching those of thousands-year-old materials. These advancements could lead to stronger metals and faster-acting pharmaceuticals., Computer simulations confirmed the findings, revealing a correlation between molecular structure and physical properties.
A new JQI photodetector uses an adaptive network of detectors with feedback to read quantum information with minimal uncertainty. By combining multiple stages and using phase reference waves, the system can beat the standard quantum limit for quaternary encoding.
Astrophysicists found that wide binary stars have a significant impact on planetary systems, causing violent disruptions and scattering planets. The researchers conducted computer simulations and found that planets in these systems are often ejected to interstellar space.
Researchers at Joslin Diabetes Center have identified TRIP-Br2 as a major regulator of energy metabolism and fat storage. In mice fed high-fat diets, TRIP-Br2 levels were elevated in visceral fat, leading to increased fat accumulation and decreased energy expenditure.
Researchers used structured expert elicitation to assess future sea level rise from ice sheets, predicting a 29cm median estimate by 2100. The study's findings suggest a conceivable risk of a rise of greater than 1m by 2100, with uncertainties surrounding the cause of recent ice sheet mass loss.
Researchers at Newcastle University used X-ray Photoelectron Spectroscopy (XPS) to analyze the build-up of hydrocarbons on replica kilograms, finding that a suntan could help remove contamination and bring prototype weights back to their ideal mass. The study highlights the significance of maintaining precise measurements in internatio...
A specific protein, Protein S, is crucial for maintaining a healthy retina through photoreceptor pruning. This process prevents retinal degeneration and blindness. The study also highlights the protein's role in other systems, such as the immune and reproductive systems, where its activation has been observed.
A new study estimates that up to 1.5 million EU children are born each year with mercury exposures above the safe limit, resulting in a potential lifetime earning loss of €8-9 million per person. Exposure reduction could equate to €10 billion per year in benefits.
Scientists from University College London have found that animal cells exhibit poroelastic behavior when mechanically stimulated, similar to organs within the body. The rate of cell deformation is limited by how quickly water can redistribute within the cell interior.
A research team from Université Laval has discovered a molecular pathway by which morphine can increase pain, leading to potential new strategies to improve treatment of post-operative and chronic pain. The researchers identified specialized cells called microglia as the culprit behind morphine-induced pain hypersensitivity.
Scientists at Potsdam Institute for Climate Impact Research propose a new method for measuring system stability, which could help predict tipping points in the Amazon rainforest and assess cancer risk. By analyzing data from diverse systems, researchers found that basin stability is a key factor in determining stability.
Researchers have identified four new regions on the human genome linked to Behcet's disease, which is characterized by inflammation of blood vessels and potential blindness. The study provides insights into genetic factors contributing to the disease and suggests new therapies for treatment.