The Society of Nuclear Medicine and Molecular Imaging has published the first guidelines for brain amyloid imaging in Alzheimer's disease, providing a framework for healthcare practitioners to determine when to order this test. The guidelines emphasize that amyloid PET imaging should be used judiciously, particularly among elderly indi...
A randomized trial shows that the dual-hormone artificial pancreas system improved glucose levels and reduced hypoglycemia compared to conventional pump treatment in patients with Type 1 diabetes. The system delivered insulin and glucagon using continuous glucose sensor readings and an intelligent dosing algorithm.
Research suggests that being in a position of power can enhance subjective well-being through increased feelings of authenticity. The study found that powerful individuals are more content and experience greater happiness due to their ability to act in congruence with their internal desires and inclinations.
A University of Central Florida professor has discovered a protein present in several types of cancer that could help prevent tumors from coming back. The protein, KLF8, appears to protect tumor cells from drugs and aid their regeneration.
IST Austria professor Peter Jonas is one of three Austrian collaborators in the €1 billion Human Brain Project. He contributes his research on cellular and subcellular parameters, crucial for accurate modeling of the brain.
The Human Brain Project will integrate data across all scales to improve understanding of brain development and combat brain disorders. Led by McGill University's Dr. Alan Evans, the project aims to reconstruct the brain in supercomputer-based models and simulations.
A new study by Johns Hopkins Medicine found that hospitalists nationwide report daily patient loads frequently exceed safe levels, posing risks to patients' safety and quality of care. The study revealed that one in five physicians feels their workload puts patients at risk for serious complications.
The radial approach for percutaneous coronary interventions (PCI) is associated with reduced bleeding complications and improved survival rates, particularly in STEMI patients. The European Society of Cardiology recommends radial access as the default strategy for PCI in high-risk acute coronary syndromes.
Researchers found that the lateral and orbital regions of the frontal cortex interact during drug-related cues, suggesting that addiction may result from abnormal brain circuitry. The study's findings suggest that a therapeutic approach for addiction could be developed by targeting this neural circuit.
Researchers at Harvard University have developed color-changing photonic fibers inspired by nature, which can pass through a full rainbow of colors as they're stretched. The fibers' superior mechanical properties make them versatile for various applications, including smart sports textiles and sensors.
A new technique called Bru-Seq allows researchers to label newly created RNA, enabling them to analyze the synthesis and stability of RNA in cancer cells. This breakthrough has the potential to provide deeper insights into gene expression and identify early warning signs of disease.
A new paper argues that current approaches to pandemic preparedness are flawed and propose alternative strategies. By prioritizing the needs of the world's poorest and most vulnerable people, we can develop more effective responses to pandemics. This approach would involve re-examining the role of pharmaceuticals, improving disease sur...
The European Commission has chosen the Human Brain Project, a decade-long research initiative backed by 1.19 billion euros, to study the human brain. Eight Israeli scientists will lead a team from top research institutions across Europe and the world.
Researchers discovered a paradoxical relationship between diminished mitochondrial function and increased insulin sensitivity in mice. The study found that mice with mitochondrial mutations lived longer and had reduced body fat due to increased fat utilization.
A special issue of Industrial Biotechnology explores innovative uses of nanotechnology in food and agriculture, including nanoparticle bioactivity, soil denitrification, and nutrient microencapsulation. Researchers discuss promising applications and methods for industrial biotech innovation.
A systematic review of 24 randomized clinical trials found significant observer bias in nonblinded outcome assessment, favoring a more beneficial treatment effect. The study recommends using blinded assessors to remove this bias and suggests that conscientious nonblinded assessors may overcompensate for expected biases.
A new peer-reviewed journal will identify crucial LGBT healthcare needs and provide a much-needed authoritative source for LGBT health research. The journal will promote optimal healthcare for millions of sexual and gender minority persons worldwide by focusing on their specific health concerns.
A national audit of percutaneous coronary interventional procedures found improved treatment times and increased use of primary PCI. The UK's PCI centers expanded services to treat more patients with acute coronary syndromes, reducing delays and improving patient outcomes.
Computer simulations show that nanoparticles of silicon BC8 can generate multiple electron-hole pairs per photon, increasing maximum efficiency to 42% beyond conventional solar cells. Using parabolic mirrors to focus sunlight could further boost efficiency up to 70%
A new compound, diisopropylammonium bromide (DIPAB), has been created as a ferroelectric material with low environmental impact and economical benefits. It can be processed easily from aqueous solution and may replace traditional materials in the production of electronic devices.
A recent study published in Clinical Gastroenterology and Hepatology found that injecting botulinum toxin A (Botox) into the stomach does not cause weight loss. The Mayo Clinic researchers used a double-blind, randomized, placebo-controlled trial to compare the effects of BTA to placebo.
A new study by University of Illinois researchers reveals that lipids in the cell membrane form larger domains than previously thought, with cholesterol playing a key role in their organization. The findings challenge current understanding of cell membrane structure and function.
A study of over 6,000 American adults found that incorporating short bursts of physical activity into daily life can be beneficial for improving health outcomes such as metabolic syndrome and high blood pressure. Researchers suggest making movement a way of life by adding activity to everyday tasks like walking or raking leaves.
According to a new theory by Mats Alvesson and André Spicer, functional stupidity can raise productivity in organizations by promoting unity and consensus. However, this 'stupidity' can also lead to risks and problems if critical questions are not posed about decisions and structures.
Researchers at MIT have developed a new type of vaccine-delivery film that gradually releases DNA coding for viral proteins, potentially overcoming safety risks and improving effectiveness. The film is implanted under the skin using microneedles and degrades over time, releasing the vaccine over days or weeks.
Researchers found a significant decrease in carotid intima-media thickness one year after islet transplant, indicating slower atherosclerosis progression. Patients achieved insulin independence and showed improved glycemic control.
A team of researchers has discovered a significant mutation in a LINC family protein that could lead to new treatments for hearing disorders. The mutation causes chaos in the cell's anatomy, leading to devastating effects on cells responsible for hearing.
A new study finds that women treated with lumpectomy plus radiation have improved survival rates compared to those who underwent mastectomy, regardless of age or tumor type. The research suggests that less invasive surgery may be an effective alternative for treating early stage breast cancer.
Researchers predict significant changes in summer ranges of endangered Indiana bats due to climate change. Suitable habitats are expected to shift to the northeastern US and Appalachian Mountains.
Researchers at Mayo Clinic find that cardiac disease is associated with increased risk of mild cognitive impairment, particularly among women. The study suggests that preventing and managing cardiac disease may help reduce the risk of non-Alzheimer's dementias.
A new analysis found that lumpectomy plus radiation provides better survival rates than mastectomy for early breast cancer, especially among women over 50 with hormone-sensitive tumors. This suggests that breast-conserving treatments are a viable option for many patients.
Researchers at Yale University have defined the genetic landscape of uterine serous carcinoma (USC), a chemo-resistant form of endometrial cancer. The study identifies three previously unknown genes that play a role in tumor growth and development, offering new avenues for personalized therapy.
A recent study suggests that climate change could result in earlier onset and increased severity of flu seasons. The research team analyzed waves of influenza and climate patterns in the US from 1997-1998 to present, indicating a pattern where warm winters are followed by heavy flu seasons.
A study published in Physiological and Biochemical Zoology found that birds with pheomelanin-based plumage coloration had higher survival rates than those without it. The researchers suggest that the production of this pigment may help sequester excess amino acids, providing a beneficial effect under certain conditions.
The ACIP has updated its recommended 2013 adult immunization schedule to include new guidelines for the use of pneumococcal conjugate and influenza vaccines. The updated schedule also recommends routine Tdap vaccination for adults aged 65 or older, pregnant women, and all patients over 6 months old against influenza.
A recent study by the USDA Forest Service's Pacific Southwest Research Station has found that fisher populations in the southern Sierra Nevada are stable. The research, which monitored fisher distribution across a 7,606-square-mile area over eight years, found no increase or decrease in population numbers.
A recent analysis published in Archives of Sexual Behavior suggests that the widespread use of penicillin in the 1950s led to a rapid decline in syphilis and subsequently marked the beginning of the modern sexual era. As syphilis became more treatable, people began having more risky non-traditional sex.
Researchers discover that urban heat generated by metropolitan areas can cause continental-scale surface warming in high latitudes, leading to remote temperature changes. The study suggests that the influence of energy consumption should be considered in computer models to predict future climate change.
Researchers expose berry extracts to human saliva to see what health-promoting substances survive. Anthocyanins, responsible for berries' colors, are more susceptible to degradation in the mouth.
Scientists develop the first maturation-based disease model for arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) using patient skin cells. The model mimics adult-onset disease by inducing adult-like metabolism, revealing metabolic malfunction and abnormal protein activation as key drivers of the disease.
A new study reveals that human activities in cities alter atmospheric circulation patterns, leading to significant warming in northern Asia and North America. The study found that the 'waste heat' generated by urban areas can widen the jet stream and increase temperatures across large distances.
Researchers have uncovered the elastic properties of spider silk, with variations among fibers, junctions, and glue spots. The findings provide a blueprint for structural engineering of strong, stretchy, and elastic materials.
Research at Ultra Short Pulse High Intensity Lab in TIFR has found a novel scheme to accelerate neutral particles over millimeters using lasers. The concept uses powerful lasers to strip electrons from argon atoms, accelerating charged ions to high energies.
A study published in BioMed Central's Stem Cell Research & Therapy journal found that stem cells from bone marrow or fat improved brain and nerve repair after stroke in rats. The treated animals showed significant functional recovery, even without the stem cells migrating to the damaged area.
A recent study by Cold Spring Harbor Laboratory researchers has identified a specific class of neurons in the central amygdala as crucial for encoding and recalling fear memories. The team used optogenetics to activate these neurons, which release neurotransmitters that enhance or inhibit synaptic connections, leading to fear responses.
Researchers used dispensary records to measure the effect of forest fires on people with chronic lung diseases. The study found that even small increases in smoke were associated with higher salbutamol dispensations, highlighting the impact of pollution on public health.
Scientists at the University of California, Berkeley, have found a link between poor sleep, memory loss and brain deterioration in older adults. Boosting 'slow wave' sleep may help restore memory, suggesting a potentially new treatment avenue for age-related memory loss.
Researchers at A*STAR's Genome Institute of Singapore discovered four processes that cause mutations in gastric cancer, including one triggered by bacterial infection. These findings pave the way for diagnostics and targeted therapy, with potential implications for improving treatment outcomes.
GATA3 acts downstream to activate microRNA29b, which stops tumor cells from spreading by inhibiting genes involved in metastasis. The absence of GATA3 allows cancerous cells to break free and induce inflammation and new blood vessel formation.
Rice University scientists develop a technique to combine single-atom-thick graphene and hexagonal boron nitride into sheets with controlled patterns. The new method enables the creation of fully functional devices with circuits on the same scale as current semiconductor fabrication.
Researchers find that hot electrons generated by laser pulses cause ultrafast demagnetization in nickel, not the light itself. The study suggests a new possibility for spintronics research.
A new study by Oregon State University researchers found that middle-aged adults are struggling to balance the demands of caring for both young adult children and aging parents. While most feel positive about helping their kids, many struggle with supporting their aging parents due to increasing needs and uncertainty.
A new single-photon detector has been developed, achieving a previously unattained detection efficiency of 91% and low error rate. The detector's high performance enables reliable detection of single photons, crucial for optical data transmission and quantum computation.
Researchers found that stress accelerates prostate cancer development in mice, while a genetic mutation in the NESP4 gene disrupts a cellular complex essential for hearing. Combining green tea extract with vardenafil enhances anti-cancer effects in a mouse model of multiple myeloma.
A new study by UAlberta researcher Trish Reay suggests that Primary Care Networks can thrive with strong leadership, redefined workspaces, and creative discord. The PCN model allows physicians to practice medicine in a team-based approach, improving patient care and doctor satisfaction.
A recent study found that stress can accelerate prostate cancer development in mice, with adrenaline blocking cancer cell death. Conversely, drugs that inhibited adrenaline signaling ablated the effect of stress on prostate cancer. This suggests that beta-blockers could enhance the effectiveness of anti-cancer therapies.
A new study by Oregon State University found that cows fed flaxseed produced milk with lower saturated fat and higher omega-3 levels. The study also found improvements in butter and cheese, but suggested that the increased polyunsaturated fats did not compromise their nutritional value.
A Dartmouth study suggests that increasing competitor and predator beetle populations can prevent population explosions of pine beetles, a major forest pest. The research confirms that some species, like the southern pine beetle, exhibit extreme fluctuations in abundance with no middle ground.
Cyclone Garry's powerful thunderstorms fueled heavy rainfall over the open waters of the Southern Pacific Ocean. The storm was predicted to weaken while moving toward the southeast, eventually becoming an extra-tropical cyclone.
IRHOM2 is a protein that regulates TACE on immune cells, and blocking it could provide an effective treatment for rheumatoid arthritis. Researchers found that mice deficient in IRHOM2 were protected from inflammatory arthritis.