Scientists have designed nanoparticles that can flip from a sphere to a net-like structure in response to tumor signals, accumulating at the site of cancer. This new approach aims to target treatments specifically to diseased cells, overcoming current limitations.
Experiments show high sinking speed for dead gelatinous plankton species, contributing to the biological pump. Fast sinking provides high-quality food resources for benthic organisms and releases CO2 that can be stored without direct contact with the atmosphere.
A study by GOJO shows that adopting electronic hand hygiene systems can lead to sustained improvement in compliance rates. The research found a significant increase in hand hygiene compliance over baseline during the intervention period, with a sustained improvement for approximately two months post-intervention.
A study by University at Buffalo researchers has identified a novel function of the protein presenilin in controlling the speed of molecular motors along neuronal highways. This regulation may prevent deadly blockages in neurodegenerative diseases like Alzheimer's, offering hope for new treatments.
Lawrence Livermore scientists have discovered a new technique to remove and store atmospheric carbon dioxide while generating carbon-negative hydrogen. The process uses electrolysis to produce alkaline solution that can neutralize ocean acidification, potentially saving marine ecosystems.
A new study reveals that childhood bullying can significantly increase the likelihood of self-harm in late adolescence. The research found that those subjected to chronic bullying over several years at primary school were nearly five times more likely to engage in self-harm six to seven years later.
A systematic review found that women who have experienced domestic violence are more likely to develop perinatal mental health disorders such as depression, anxiety, and post-traumatic stress disorder. High levels of symptoms were linked to increased odds of experiencing domestic violence during pregnancy or over a lifetime.
A 10-minute test for frailty can predict increased risk of death and frequent hospitalization among kidney dialysis patients. The test measures physiological reserve and suggests that dialysis patients are undergoing premature aging, leading to higher mortality rates.
Researchers have identified two ruthenium-based complexes that target cancer cells more effectively and are less toxic than current chemotherapies. The complexes, which seem to target cells in hypoxic states, could complement widely used platinum-based therapies like cisplatin.
Adult wild chimpanzees exhibit a strong association between age and malaria parasite detection rates, with significantly lower positivity in adults. This suggests that individuals reaching adulthood mount an effective protective immunity against malaria parasites, consistent with human observations.
Researchers have developed a device that captures and isolates potentially high-risk cancer cells, enabling doctors to access and identify cancerous cells in the bloodstream. This technology may revolutionize conventional biopsy practices and significantly advance personalized medicine.
A recent study published in Cancer found that African American men with prostate cancer face longer treatment delays than their Caucasian counterparts. The analysis of SEER-Medicare registry data revealed an average delay of 7 days for African American patients, compared to 4 days for Caucasians. Additionally, African Americans were mo...
A study by Brown University found that three out of five hikers brought seven or fewer items, while only 18 percent packed all 10 essential items. Young and inexperienced hikers were most likely to lack multiple items recommended by the State of New Hampshire's HikeSafe program.
Researchers developed a novel class of peptidomimetic drugs that interrupt androgen receptor signaling in prostate cancer cells, preventing growth. The agents show promise as a potential therapeutic approach for men with advanced disease.
A recent study published in the Journal of Thoracic Oncology found that digital chest tomosynthesis (DT) holds promise as a first-line lung cancer screening tool. DT improved sensitivity in detecting lung nodules compared to conventional chest radiography, while providing lower costs and radiation dosages.
A study by US and German experts analyzed secret tobacco industry documents to conclude that the companies have a history of intentional deception. The authors argue that regulatory bodies should not consider tobacco companies stakeholders due to their vested interests, which could manipulate scientific discourse and harm public health.
The camel genome has been fully sequenced for the first time, providing insights into breeding strategies and adaptations to harsh desert environments. The research reveals a close genetic relationship between the Bactrian and dromedary camels, highlighting their unique characteristics.
A novel small molecule has been developed to block the function of androgen receptors, which promote prostate cancer growth. The compound prevents cancer cells from recruiting protein partners and blocks their growth, showing promise for treating prostate cancer.
Researchers have identified a potential therapeutic target for pancreatic cancer by inhibiting the activity of GSK-3 alpha, a protein that promotes oncogenic KRAS function. The study found that blocking GSK-3 alpha resulted in an anti-tumor response in mouse models, suggesting a viable treatment option.
Researchers found that treatment with Tamiflu did not reduce viral load in three patients who became severely ill, leading to concerns about resistance. Genetic testing confirmed the presence of a mutation characteristic of neuraminidase inhibitor resistance.
Scientists at Rice University and Honda Research Institute have created a hybrid material that combines diamonds, nanotubes, and graphene for superior thermal management. The researchers successfully grew vertically aligned carbon nanotubes on diamond using graphene as a middleman, demonstrating its potential as a heat sink.
Researchers at OHSU's Vollum Institute have discovered a new NMDA receptor subtype that is the most common at synapses, contradicting previous drug development efforts. The study suggests that this subtype may be a new target for developing effective therapies for neurological disorders.
Dr Gao's project aims to reduce material waste and defects in products like photovoltaic films and micro-engineered products. The UK-based researcher will develop a high-speed inspection technique using white light spectral interferometry and signal processing.
Researchers have found a way to eliminate a gene that causes cells in the bone marrow microenvironment to die, allowing donor cells to replace them. This breakthrough could lead to improved bone marrow transplant therapy for patients with blood diseases such as leukemia and multiple myeloma.
A recent study by University of Cincinnati researchers highlights the increasing problem of prescription drug abuse among youth, with males and high school students at a higher risk. The study found that pro-social behaviors, such as strong connections with parents and teachers, can reduce the odds of abusing prescription drugs.
A new study found that people tend to distort their sexual behavior to conform to cultural expectations of masculinity and femininity. In contrast, non-sexual behaviors are not subject to the same level of scrutiny, with individuals more willing to admit to stereotypes for their gender in these areas.
Researchers at Georgia Institute of Technology create a new type of paper that repels a wide variety of liquids, including water and oil, using the 'lotus effect'. The modified paper could be used as a foundation for inexpensive biomedical diagnostics and provide an improved packaging material that is recyclable and sustainable.
Dr. Jennifer Gillette is studying the role of hematopoietic stem cells in directing the creation of new blood vessels at the site of a crisis, such as a heart attack. Her research aims to improve treatment responses for heart disease and potentially benefit cancer patients who receive hematopoietic stem cell transplants.
Theorists have found new methods to determine the likelihood of quantum encryption scheme failure, enabling device-independent cryptography. This allows for the estimation of failure probabilities without relying on assumptions about the reliability of devices.
A new study found that disabled Medicare patients under 65 who face cost barriers to medication adherence are more likely to have emergency department visits. The study revealed that 38.3% of patients with severe cost-related non-adherence had at least one ER visit, compared to 27.5% without CRN.
The first-ever enterovirus 71 vaccine has been shown to be highly effective in protecting young children against the potentially deadly hand, foot, and mouth disease. The vaccine demonstrated 90% protection against clinical EV71-associated HFMD and 80.4% against EV71-associated disease for at least 12 months.
Researchers developed a new model that integrates both historical and psychological perspectives on art appreciation. This approach acknowledges the importance of artistic understanding in assessing value and meaning, and can be applied to various forms of art.
Sarcomatoid lung carcinomas are rare and aggressive diseases resistant to chemotherapy. Researchers found higher levels of programmed death ligand-1 (PD-L1) in these tumors, which may lead to the use of anti-PD-1/PD-L1 targeted therapies. This discovery supports potential novel immunotherapy approaches for this difficult-to-treat disease.
The NHS receives millions of pounds annually in revenue from promotions to pregnant women, raising concerns over commercial interests influencing healthcare decisions. Trusted organizations, including the Royal College of Obstetricians and Gynaecologists, profit from selling advertisers access to pregnant women through promotions.
Research explores Arctic sea ice impact on atmospheric circulation and surface temperatures, revealing significant effects beyond the Arctic region.
Researchers at Johns Hopkins Medicine found that individually harmless genetic variations affecting related biochemical processes may team up to increase the risk of schizophrenia. The study suggests a buildup of mutations in a pathway related to the disease can be the culprit for the mental disorder.
A tropical low-pressure system, System 92E, is developing near southwestern Mexico and may become Tropical Storm Barbara by May 28. The National Hurricane Center expects the storm to consolidate and bring heavy rains to southern Mexico and western Central America.
A new strain of algae discovered in Colorado's Rocky Mountains has been found to grow at temperatures approaching freezing and accumulate large intracellular stores of lipids. The algae produces the highest quantity of lipids when grown under high light and low temperatures, making it an ideal source for biofuel production.
Researchers found a 'weekday effect' in mortality rates for patients undergoing elective surgery, with higher risks at the weekend and end of working week. The study suggests poorer quality of care may contribute to this, particularly for patients with more diseases or previous admissions.
A study by Dr. Susana T.L. Chung reveals that the visual system of older adults with central vision loss is still plastic and can be modified through experiences. Perceptual learning techniques targeting the preferred retinal location led to an average 50 percent increase in reading speed, improving daily functioning.
International researchers found that all seven psychotherapeutic interventions have comparable effects on depressive symptoms, regardless of patient group or therapy type. The therapies worked equally well for individual and group therapy, as well as internet-based interactions.
A new LSUHSC paper has been selected as the Best Paper of the Year by the National Cancer Registrars Association for its innovative evaluation of cancer stages. The study found that lung and prostate cancers had the highest percentages of unknown stages, with non-hospital reporting sources being a key predictor.
In large quantum systems, entanglement becomes ubiquitous above a threshold of about 200 particles, enabling super high-speed communications and quantum computing. The study provides parameters to harness this property.
Researchers at the University of Alberta have identified a genetic marker on chromosome 4 associated with sporadic breast cancer in Alberta women. The study, published in PLoS One, used DNA scans from over 7,200 women and found that those with sporadic breast cancer frequently carried this marker.
A new study reveals that bumblebees use a 'buzz' warning signal to scare away birds from their freshly built nests. The researchers observed that the birds were distressed and often flew out of the nest when exposed to the buzzing sound.
Researchers at Washington State University found that being confident can increase a pundit's followers by nearly 17%, while accuracy only boosts it by 3.4%. The study used over 1 billion tweets to analyze the relationship between confidence and popularity.
A Cornell robot has been programmed to anticipate human actions, enabling it to step in and offer a helping hand. The robot uses a Microsoft Kinect camera and a database of 3D videos to identify activities and predict future actions.
A new study led by the University of Pennsylvania reveals that the New Jersey coast has experienced a 10,000-year record of continuous sea-level rise, with varying rates of increase over time. The research suggests that climate change may trigger catastrophic melting of ice sheets, leading to higher rates of sea-level rise and increasi...
A new field experiment by University of Chicago economists found that women are more likely to opt-out of charity donations, especially when given the option. In contrast, men's giving was slightly affected, with women giving only half as much as before in situations where they could avoid donating.
Research suggests producers feeding high levels of DDGS reduce fat softening by limiting feed in last weeks before harvest. Pigs fed diets with saturated fats did not show firmer belly flop distances, contradicting long-held assumption that they improve fat quality.
A former University of California, Riverside graduate student built a system that replicates a human colon, septic tank, and groundwater to understand the impact of bacteria on groundwater. His research found that pathogens could potentially linger longer in aquatic environments, posing a risk to water quality.
Researchers at Karolinska Institutet discovered that aspirin-triggered resolvin D1 can prevent and treat postoperative cognitive dysfunctions by resolving inflammation. The study found that treatment with a single dose of AT-RvD1 protected the brain from memory dysfunction after surgery.
A new study suggests that the ability to pick up on statistical regularities is a key factor in learning a second language. American students who performed well on a task measuring their capacity for statistical pattern recognition were found to be more successful in picking up Hebrew over two semesters.
Scientists discovered that foraminifera may be responsible for the decline of stromatolites and the emergence of thrombolites. The researchers found evidence of foraminifera in both types of structures, suggesting a possible link between their disappearance and appearance.
The Institute for Genomic Biology will develop foundational synthetic biology technologies and computational platforms for genetic modification of plants and animals. The grant aims to address grand challenges in human health and environmental sustainability, with potential applications in crop yields and disease treatment.
Researchers at the University of Exeter have developed a vaccine that protects against necrotic enteritis, a severe poultry disease caused by Clostridium perfringens. The vaccine targets the bacterium's NetB toxin, allowing for effective prevention and control of the devastating disease.
A new study in the Journal of Quaternary Science explores the historic impact of forest diseases on vegetation change. The research suggests that human activity, such as international seed trade, is a major factor in frequent pathogen outbreaks over the last 100 years.
Researchers have developed new superresolution and segmentation methods for magnetic resonance images to analyze structural brain differences in psychotic patients and their healthy relatives. These methods improve the quality of images and enable automatic calculations of desired sizes, leading to a better understanding of psychosis.
Researchers developed a set of equations to estimate the initial dose of intrathecal spinal pain relievers, avoiding the need for epidural anesthesia trials. This approach could shorten time to satisfactory pain control in patients with uncontrolled cancer pain, allowing them to spend more of their remaining days at home.
UCLA will study the use of videoconferencing technology to deliver integrated behavioral and mental health services to children in community primary care settings. The project aims to provide effective, efficient, and family-centered care to children in low-income communities.