A longitudinal review found moderate exercise can prevent episodes of depression, even at low levels (20-30 minutes/day). Researchers analyzed over 26 years of research to demonstrate the impact of physical activity on mental health.
Researchers found a fat recycling system within pancreatic beta cells that regulates insulin production, providing a promising target for future diabetes treatments. By preventing this system from breaking down unwanted fats, scientists were able to increase insulin secretion.
A study by Loyola University Medical Center researchers found that nurses in a burn intensive care unit experience moral distress, which can lead to depression, anxiety, and job burnout. An educational intervention reduced moral distress scores, but not significantly enough to last six weeks after the program.
A new approach to describing new species uses big data techniques like next-gen sequencing and barcoding. This allows scientists to create detailed datasets and make it easier to manage biodiversity information.
A study published in Psychological Science found that cognitive reappraisal can actually have negative effects on psychological health when dealing with controllable stressors. This challenges the long-held notion that reappraisal is always beneficial for emotional well-being.
Researchers quantify the extent of ancient oxygen-free and hydrogen sulfide-rich waters in the ocean during a major extinction event 93.9 million years ago. This discovery highlights the significant impact on ocean chemistry and biological activity, suggesting that even limited euxinia can have profound effects on marine life.
Using genetic algorithms, researchers at Columbia University have developed an inverse design framework to create novel nanostructured materials. The study shows the potential of machine learning and
Researchers at Simon Fraser University are using advanced Nano X-ray Computed Tomography tools to visualize hydrogen fuel cells, enabling the development of more durable and efficient fuel cells. The new technology is expected to play a key role in reducing harmful emissions in the transportation sector.
Researchers found that posterior intercostal lymph nodes have predictive power for mesothelioma patients, with patients without cancer in these nodes having significantly longer overall survival rates. The study suggests including these lymph nodes in the mesothelioma staging system.
A new study published in the British Medical Journal found that lowering blood pressure can significantly reduce the risk of cardiovascular events among people with kidney disease. The study suggests that any type of blood pressure-lowering drug is effective in preventing these events, making it a simple and affordable treatment option.
Remimazolam, a benzodiazepine-type sedative drug, has shown promising results as an alternative to conventional sedatives in colonoscopy procedures. The medication provides adequate sedation with a fast onset and quick recovery time, making it a valuable option for patients undergoing brief medical procedures.
Researchers at the University of Illinois Chicago have discovered a molecular switch that causes small, beneficial clots to enlarge further during wound healing. By blocking this switch, potent anti-clotting drugs can be developed to prevent large clots from forming while preserving the body's ability to form primary clots.
Early, aggressive drug treatment shows promising results in patients with psoriatic arthritis, reducing joint damage and disability. A £550,000 clinical trial involving over 200 patients found significant improvements in joint and skin outcomes with tight control of disease activity.
Researchers found that tumors may switch dependence from VEGF-A to related growth factors like VEGF-C, VEGF-D, and placental growth factor when targeted by bevacizumab. This change allows colorectal cancer to continue growing despite the blockage of VEGF-A.
New findings show STELARA significantly inhibits structural damage progression at week 24 and maintains effect through two years. Treatment with STELARA results in reduced total psoriatic arthritis modified vdH-S scores compared to placebo.
Case Western Reserve University researchers aim to develop processes that can be used by industry to manufacture Janus particles, which could carry paired medicines or provide unique optics for displays. The engineers focus on creating high-yield nanomanufacturing with simple processes.
A new DNA vaccine, p(Aβ3–10)10-C3d-p28, was developed to induce a Th2 immune response against amyloid-beta in Alzheimer's disease mice. The vaccine successfully elicited high titers of anti-amyloid-β antibodies and shifted the cellular immune response towards a Th2 phenotype.
A new study published in CMAJ found that the odds of patients with brain injury deteriorating to neurologic death decreased over a 10-year period, likely due to improved care and prevention measures such as road safety initiatives and enhanced clinical care.
A new study at Washington University School of Medicine found that nurturing home life can offset negative brain changes in poor children. The research suggests teaching nurturing skills to parents can provide a lifetime benefit for their children.
A study found that wearing high heels while running leads to increased knee motion, joint forces, and risk of ankle sprains. Regular use may contribute to osteoarthritis in the knees.
The Geological Society of America is presenting a late-breaking session on the 2013 Colorado flood event, which was triggered by unprecedented heavy rainfall. Speakers will discuss causes, processes, and effects of the flood, including its impact on dams, infrastructure, and lives.
A Korean research team from Ulsan National Institute of Science and Technology (UNIST) developed a high-performance metal-free electrocatalyst for oxygen reduction reaction using covalently functionalized graphene nanosheets. The new catalyst shows superior stability compared to commercial Pt/C catalysts.
Researchers have verified the classical Landau-Squire theory in a nanoscale fluid jet, measuring flow rates of tens of pico liters per second. The findings suggest that the Navier-Stokes equations hold true at molecular scales, with potential applications in ultra-low-volume injectors and microfluidic logic circuits.
Researchers found that rhesus macaque monkeys have specialized nerve cells in their brains that respond to images of snakes. This suggests that primates may have evolved to detect and avoid snakes due to the presence of venomous snakes during their ancestors' time.
A study has found that potassium chloride (KCl) fertilization is seldom effective in increasing grain yield and can even lead to significant yield reduction. The research also highlights the potential negative impacts of KCl on soil health, including increased cadmium accumulation and changes in soil physical properties.
A recent study published by the American Academy of Pediatrics found that young athletes who spend twice as much time in organized sports than free play are more likely to be injured. The study also found that those who specialize in a single sport for extended periods are at a higher risk of overuse injuries.
LIMP-2 possesses a novel protein fold and nanoscale transport tunnel, enabling it to transport enzymes and lipids. This discovery could lead to the development of therapies for diseases like Gaucher's, where enzyme deficiency causes lipid accumulation.
The sun continues to produce mid-level and significant solar flares, including an X1.0 flare on Oct. 27 and an M5.1 flare on Oct. 28, potentially impacting Earth's atmosphere and electronic systems. The recent activity is part of the sun's normal 11-year activity cycle.
Scientists at PNNL found that new rooftop units reduce energy costs by 41% compared to current units. If widely adopted, these devices could idle eight average-size coal-fired power plants in a year.
NASA's Aqua satellite captured the last image of Typhoon Lekima before it weakened into an extra-tropical cyclone. The typhoon maintained its eye and surrounded clouds, but its winds were rapidly decreasing.
A UT Dallas study shows that preschoolers tend to trust nice people with no expertise over mean experts who clearly know the answer. Children as young as 4 years old recognize expertise in specific areas and prioritize niceness when deciding whom to believe.
A study by the American Academy of Pediatrics found that different helmet brands and custom mouth guards did not reduce concussion risk in high school football players. The study tested various mouth guard brands, including custom-fit mouth guards, and new and older football helmets.
A new study mapping gold mining in the Peruvian Amazon reveals a 400% increase in mining extent from 1999 to 2012 and tripled average annual rate of forest loss. The research used satellite monitoring and field surveys to detect small-scale mining operations, confirming up to 94% accuracy.
Researchers have discovered that tumors with specific microRNA segments are more likely to recur after surgery. Elevated blood levels of these genetic markers may also indicate a higher risk of recurrence. The findings suggest a potential for using microRNA profiles to classify thyroid tumors and monitor cancer progression.
A new super-thin silicon membrane developed at the University of Rochester enables the creation of miniaturized pumps that can be powered by small batteries, paving the way for portable diagnostic devices. This breakthrough could lead to applications in medical and electronic device cooling, as well as cost-effective fabrication methods.
A study at Washington University in St. Louis found that a small molecule called VIP can temporarily desynchronize brain cells, but also enables them to re-synchronize more quickly to abrupt shifts in daily light-dark schedules. This effect may be useful for travelers and shift workers who struggle with jet lag.
Researchers from Uppsala University use PET scanning to visualize elevated levels of NK1 receptors in painful tissue, shedding light on the underlying mechanisms of chronic tennis elbow. The study provides a promising diagnostic method for localizing and diagnosing soft tissue pain.
A new study reveals that presenilin works with enzyme GSK-3ß to control material transport through neurons. Low levels of presenilin or high levels of GSK-3ß can cause uncoordinated movement, resulting in dangerous blockages. Researchers propose a potential pathway for early intervention through drugs.
A comprehensive review from the American Heart Association emphasizes the importance of personalized care for older adults with cardiovascular disease. The statement highlights key factors such as lifestyle changes, medication regimens, and revascularization strategies that can provide benefits and risks.
Research finds that early skin-to-skin contact in the delivery room significantly increases exclusive breastfeeding rates, particularly when mothers intend to breastfeed exclusively. Skin-to-skin contact and maternal intention are strongly associated with successful breastfeeding outcomes.
A University of Oklahoma research team found that a commonly used aquatic crustacean, Hyalella azteca, can adapt to polluted conditions and become an unreliable source of information about ecosystem health. The species' genetic mutations allow it to survive at high doses of pyrethroid insecticides.
A new drug, Linaclotide, has been found to effectively relieve abdominal pain in IBS-C patients through a novel physiological pathway. The study's findings provide significant relief for approximately one-third of IBS-C sufferers who have struggled with this debilitating condition.
The Nanotechnology Consumer Product Inventory has been restructured to improve its functionality and scientific credibility. The database now includes qualitative and quantitative descriptors for nanomaterials and their potential exposure routes, enabling better understanding of the risks associated with consumer products.
Researchers found increased iron deposits in deep gray matter of patients with clinically isolated syndrome (CIS), a precursor to Multiple Sclerosis (MS). The study also revealed subtle brain damage and lack of correlation between iron deposits and jugular vein diameter, casting doubt on the Zamboni hypothesis.
A new study published in Arthritis & Rheumatism found that headaches in lupus patients are not linked to disease activity or specific autoantibodies. The study of over 1,700 lupus patients showed that nearly all headache episodes resolved on their own without treatment.
Researchers have developed a novel nanostructure that can carry multiple components for simultaneous detection, diagnosis, and targeted drug delivery to cancer cells. This Janus nanostructure has the potential to provide earlier diagnosis and more accurate targeting of cancer cells, reducing drug side effects.
The study found that children under 14 are four times more likely to be shot at home and are much more likely to arrive by ambulance than older teens. Older teens often walk in or are dropped off at emergency department entrances.
A study of 48 patients found higher coronary risks associated with left-sided radiation and supine body position. Targeting baseline cardiac risk factors may reduce radiotherapy-induced heart disease risks.
A new study found that higher-ranking group members manipulate perceived threats to preserve their rank, while average individuals may underestimate real threats. This study highlights the dark side of cooperation and self-sacrifice in groups.
A study published in Nature Immunology has identified two key proteins, KLF2 and S1P1, that influence immune response strategies. The findings suggest that cytokines play a major role in determining whether lymphocytes become resident memory cells or recirculate.
A new study published in Medicine & Science in Sports & Exercise found that children with poor motor performance at the start of school tend to have poorer reading and arithmetic skills than their peers. The study suggests that motor performance and movement skills are more important for academic success during the first years of school.
LLCD successfully transmitted data from lunar orbit to Earth at a rate of 622 Mbps, more than six times faster than previous radio systems flown to the moon. The demonstration validated laser communication technology for future space missions.
A global study published in the Journal of the American Medical Association, Internal Medicine found that Mondays are when smokers are most likely to think about quitting. The research monitored Google search query logs from six languages and revealed a consistent pattern of quit smoking searches throughout the week.
A new smartphone-enabled otoscope attachment and app has been shown to accurately diagnose acute otitis media (ear infections) in children. The device provides high-quality video images of the ear drum, allowing for better understanding of the child's diagnosis and treatment.
Researchers at Duke University Medical Center found that HPV subtypes affecting African-American women differ significantly from those covered by available vaccines. This disparity raises concerns about the vaccines' effectiveness in preventing cervical cancer among African-American women.
Researchers discovered that doxycycline-induced neural stem cells exhibit increased proliferative activity and inhibitory differentiation similar to tumor stem cells. This suggests a possible link between neural stem cells and the origin of brain tumor stem cells.
Researchers from University of Pennsylvania found no evidence of the endowment effect in Hadza people, a hunter-gatherer society in Tanzania. The study suggests that this bias may not be universal and could have been shaped by cultural factors rather than evolutionary history.
Researchers at University of Wisconsin-Madison have created a highly detailed structural model of the rhinovirus C, which is responsible for up to half of all childhood colds. The new model shows that the virus has distinct surface features that make it difficult for drugs to effectively target it.
The first tropical cyclone of the Southern Indian Ocean season formed on October 27 and dissipated by October 28. The storm was characterized by an elongated low-level circulation center battling wind shear.
A new algorithm proposed by MIT professor Berthold Horn aims to alleviate traffic flow instabilities, which can cause unexplained traffic jams. The algorithm uses sensor information from cars behind and in front of each other to stabilize traffic flow and reduce the risk of jams.