Researchers have devised a model of DNA's close environment under threat from low-energy electrons, revealing their effects on DNA in natural conditions. The study aims to improve current uses of radiation, such as in cancer treatments and diagnostic procedures.
Researchers create novel concept using metamaterial to study quantum entanglement and complex relationships between photons. The system enables precise measurements without losing photons, providing a deeper understanding of the transition zone between classical and quantum physics.
A recent study found that 30% of children admit to being cyberbullied, while only slightly higher than 10% of their parents reported being aware. Parents who use permissive parenting styles are more likely to be unaware of their child's online behavior.
Researchers from Fraunhofer-Gesellschaft have developed nanoparticles that selectively deliver doxorubicin to cancer cells, reducing side effects. In laboratory tests, encapsulated doxorubicin was found to be 5 times more effective than unencapsulated form in eliminating malignant cells.
A new study found that women experiencing breast cancer often experience positive outcomes, including enhanced interpersonal relationships, increased appreciation for life, and greater spirituality. Increased social support was also linked to more post-traumatic growth in these women.
NASA's GOES-East satellite image captured the oval-shaped remnants of Tropical Storm Lorenzo east of a frontal system. The remnant low-pressure area is moving northeast at 10 mph and has a 20% chance to redevelop before being consumed by the approaching cold front.
A new study from Brigham and Women's Hospital reveals four novel genetic variants associated with how people living with chronic obstructive pulmonary disease (COPD) respond to inhaled bronchodilators. The findings may reveal genetic pathways associated with the pathogenesis of COPD and identify novel treatment methods.
A recent study found that the invasive creeping daisy attracts and augments local populations of pollinating insects, including the native bee Braunsapis puangensis. This association has positive implications for crop growers and commercial honey producers in Fiji.
Hurricane Raymond has weakened to a tropical storm, with rainfall totals of over 350mm along the Mexican coast and extreme amounts in open waters. The storm is expected to move into a more favorable environment, potentially reaching hurricane status again before weakening over cooler waters by October 31
A recent study found that ursolic acid induces neural regeneration and repair after sciatic nerve injury in mouse models. The compound promoted the regeneration of injured nerve myelin sheaths and reconstructed muscular functions.
A study by Cristine Legare and André Souza found that rituals help people feel a sense of control over their environment, while Michael Norton's research on grief also highlights the benefits of rituals. This new research on Halloween rituals provides insight into human behavior and the power of ritual in shaping our lives.
The American Thoracic Society expert panel recommends that patients work with their providers to develop individualized action plans to prevent 'dyspnea crisis' episodes. These plans can include alternative relaxation and breathing techniques, medications, and oxygen therapy to ease symptoms.
Researchers found ionizing radiation exposure promotes formation of fusion oncogenes in papillary thyroid cancers. In another study, the origin of lethal prostate cancer was traced back to a small, low-grade focus in the primary tumor. Additionally, reduced reactive oxygen species production in diabetic kidneys may contribute to diseas...
A new study reverses the prevailing theory on diabetic kidney disease, finding that elevated glucose levels do not cause the condition but rather suppressing mitochondrial activity. The researchers discovered that boosting beneficial AMPK activity through lifestyle changes or drug activation can reduce kidney disease severity.
Researchers at Johns Hopkins Medicine have identified DNA sequence changes associated with schizophrenia symptoms, including delusions. Additionally, they discovered 'jumping genes' in colon cancer cells that could be used as biomarkers to monitor disease progression.
Researchers at UAB designed an antibody fragment that cleared Aβ peptide oligomers from the cerebral cortex, reversing anxiety and learning memory deficits in mice. The treatment also improved apolipoprotein levels, suggesting a potential therapeutic approach for Alzheimer's disease.
Researchers tested four portable vision screening devices on 108 pediatric patients and found that all four performed well, with comparable sensitivity and specificity ratings. The new devices, combined with updated guidelines and a reimbursement code, promise to improve early screening for amblyopia.
Researchers identified chromosomal rearrangements that result in fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers. These events promote upregulation of MAPK signaling, a common cancer-associated pathway. The study offers new understanding into how ionizing radiation exposure contributes to cancer development.
Researchers found that taking eight essential amino acids twice daily before and after knee-replacement surgeries can reduce muscle atrophy by 6.2% and speed recovery. This approach shows promise for a growing population of aging adults who face total knee replacements due to loss of mobility and pain problems.
Researchers have developed a novel, non-invasive method to measure blood sugar levels using photoacoustic spectroscopy and infrared laser light. The technology has the potential to make diabetes management easier and more reliable without pricking or using test strips.
A group of Grand Valley State University students and faculty are working with Van Andel Institute to develop new methods for early cancer detection using advanced imaging technology. The partnership has led to significant advancements in the medical imaging field, with potential applications for predicting tumor growth and spread.
The decoded kiwifruit genome shows significant genetic similarities with other plant species like potatoes and tomatoes, highlighting two major evolutionary events that occurred millions of years ago. The study provides valuable resources for kiwifruit research and breeding programs to improve fruit quality and disease resistance.
A new standard provides confidence that results from handheld Raman spectrometers can be compared accurately. The standard corrects differences in peak intensities reported by different instruments, enabling consistent measurements in emergency response situations.
A new relative of the most widespread ant genus Paratrechina has been discovered in Africa, challenging previous understanding of its native range. The newly found species, P. zanjensis, is potentially specialized to miombo woodlands and may provide insights into the biology of Paratrechina longicornis.
Researchers found that diabetic mice showed reduced reactive oxygen species production in their kidneys, linked to lower AMPK activity. This decrease was associated with lowered kidney damage and improved symptoms.
Researchers at Boston University School of Medicine have discovered a regulatory molecule, miR-4423, that is less abundant in people with lung cancer and inhibits lung cancer cell growth. This molecule may aid in diagnosing lung cancer in earlier stages and treating the disease when at healthy levels.
A recent study published by the American Academy of Pediatrics reveals that children with brain injuries are at a higher risk of developing depression. The research, which analyzed data from over 2,000 children with brain injuries, found a 4.9-fold increase in the odds of diagnosed depression compared to other children.
Researchers found that task orientation affects source memory effects in the right prefrontal cortex and hippocampus, while modulating item memory effects in the prefrontal cortex. The study highlights the possibility of the hippocampus contributing to intentional encoding of item-source associations.
The cantilever technology measures drug-bacteria interactions in real-time, detecting rupturing of individual hydrogen bonds and resolving forces of ~10 pN. It offers a sensitive alternative for drug experimentation and early detection of infectious diseases.
Research suggests that many high-risk organs are safe and should not be labeled as such. After a median of 2.4 years, 86.5% of transplants from these donors were functioning without evidence of infections. The study challenges the CDC's current classification system.
Researchers from the University of York and St Andrews have created a new structure called a quasi-random structure, which combines the advantages of quasi-crystals with periodic structures to achieve highly efficient broad-band light trapping in thin films.
A study found that different strains of gut bacteria use mucins in the human gut at varying rates. The ability to break down mucins is linked to specific gene clusters, and these differences can affect which bacteria thrive in the gut. This research may provide new insights into maintaining a healthy gut microbiome.
Tropical Storm Francisco is transitioning to a cold-core low-pressure area due to cold air and mid-latitude westerly winds. The Joint Typhoon Warning Center predicts Francisco will continue this transition as it moves northeast over the next couple of days.
A new study published in JAMA Psychiatry reveals that topiramate, an anti-epileptic drug, shows promise in treating cocaine dependence by reducing cravings and improving global functioning. The study enrolled 142 participants and found that topiramate was more efficacious than placebo.
A Northwestern University study analyzed data from over 400,000 runners in 10 large 10km road racing events. The top groups of men and women appear to be getting faster, with more sub-hour finishers among women. An increasing percentage of finishers are completing races in more than one hour.
Researchers aim to create a system that acquires data from various sensors during surgery and integrates it with pre-operative information to produce dynamic, real-time maps. This will enable surgeons to work more easily and safely, while also enabling the robot to assist in semi-automating surgical sub-tasks.
A recent study published in the Lancet found that young obese women with metabolic disorders are at a higher risk of developing high blood pressure, diabetes, and high cholesterol, which can increase their likelihood of having a stroke. In contrast, young women who are overweight or obese without metabolic disorders do not have an incr...
Researchers have developed two new microscopes that capture fast-moving cells in 3-D and reduce light exposure to preserve cell health. The iSIM microscope enables real-time super resolution imaging of small structures at high speed.
Researchers used next-generation sequencing to identify clinically relevant genetic variants associated with CAS. In eight cases, clinically significant variants were found, confirming previous reports and identifying novel associations.
A team of researchers has successfully mapped 1875 castor bean proteins using proteomics, revealing the presence of toxic allergens and ricin. The findings suggest that eliminating these substances may be difficult due to their concentration in mature beans, making it hard to harvest beans before they reach full maturity.
International experts call for a broader definition of poverty to account for risks to the unborn child, which can have devastating consequences. The World Health Organisation estimates that 200 million conceptions occur annually, mostly in disadvantaged areas, posing significant risks during pregnancy.
A genome-wide meta-analysis of COPD patients has identified novel gene variants associated with bronchodilator responsiveness. The study used data from over 6,000 patients and found that genetic determinants likely influence response to inhaled medication.
Researchers found that Itch maintains the stability of regulatory T cells (Tregs), which promotes Th2 inflammatory responses and severe airway inflammation in mice. This study highlights the importance of Itch in regulating immune responses and preventing allergic diseases.
A recent study by Boston University School of Medicine researchers found that women with multiple social barriers to healthcare faced longer delays in cancer screening follow-up. The study, which looked at 1,493 subjects enrolled in the Boston Patient Navigation Research Program, showed that social barriers were a significant obstacle ...
Researchers tracked lethal prostate cancer to determine the clonal origin of a patient's deadly disease. Using tissue samples, they identified the primary tumor site of the lethal clone, revealing that it originated from a small, low-grade foci rather than the larger high-grade region.
Salvianolic acid B, a compound found in salvianolate, has been shown to attenuate brain tissue damage and inhibit neuronal apoptosis in cerebral ischemia-reperfusion injury models. The study suggests that salvianolate increases heat shock protein expression, which may help protect against such injuries.
Researchers have discovered a novel protease complex in bacteria that operates as a molecular motor, with a constant revolutions per minute (RPM) and varying gears to shred proteins. This 'cellular shredder' plays a crucial role in DNA damage repair, gene expression, and protein quality control.
Typhoon Lekima's eye shrunk to just 4 nautical miles on Oct. 25, according to NASA data. Heavy rainfall was observed around the storm's eyewall, with rain rates reaching over 130mm/hour in the outer eyewall.
Research papers from nine vulnerable countries reveal four loss and damage pathways caused by climate stressors, including insufficient coping measures and negative economic impacts. The study highlights the need for ambitious mitigation and adaptation to prevent loss and damage that undermines sustainable development.
Researchers analyzed genealogical and medical records of Utah males, identifying distinct Y chromosomes associated with a significant excess risk of prostate cancer. The study found that nearly 73 out of 1,000 Y chromosome groups had a higher incidence of prostate cancers than expected.
Researchers have found a new, low-cost technology to reduce mercury contamination in soils and sediments, using activated carbon. The technology reduces methylmercury uptake by up to 90% without physical disturbance.
A new study reveals an independent association between sleep apnea severity and increased high sensitivity troponin T levels, a marker of early myocardial injury. Higher levels were associated with an increased risk of coronary heart disease and heart failure.
Researchers at the University of Tsukuba have identified a synthetic ligand that reduces renal fibrosis in mice by inhibiting the TGF-β/SMAD signaling pathway. This finding has implications for the treatment of patients with fibrotic diseases.
A new study from RIKEN and Keio University reveals that Pimozide can restore steroid effects on natural helper cells in severe asthmatic patients. Researchers found that thymic stromal lymphopoietin (TSLP) induces corticosteroid resistance in these cells.
Researchers at Lund University have made a breakthrough in stem cell-based treatment for stroke by developing induced pluripotent stem cells that mature into functional nerve cells. These cells, transplanted into the cerebral cortex of rats with stroke, improve mobility and demonstrate promising results.
A team of doctors and scientists at Cedars-Sinai Medical Center used stem cell technology to create neurons from patients' skin cells and block the damaging effects of a defective gene. The study provides proof of concept for a new therapeutic strategy, suggesting a potential future therapy for Lou Gehrig's disease.
Max Planck researchers demonstrate how the green alga Chlamydomonas synchronizes its two flagella using a resourceful rocking movement. The resulting mechanism is based solely on the coupling of the two movements, with no special sensors or chemical signals required.
Researchers have discovered that plankton shells contain growth bands that record daily variations in magnesium chemistry, providing a proxy for past ocean temperature. This breakthrough allows scientists to study short timescale changes in ocean temperatures hundreds of millions of years ago.
Researchers at Los Alamos National Laboratory have developed a new generation of engineered quantum dots to reduce wasteful charge-carrier interactions in QD-LEDs. This breakthrough aims to improve the efficiency and operating lifetime of these devices, making them more suitable for lighting applications.
The ASU group, in collaboration with Georgia Tech, has developed a new approach to growing InGaN crystals, promising to move photovoltaic solar cell technology toward record-breaking efficiencies. The technique, called metal-modulated epitaxy, allows for the growth of ideal crystals with uniform composition and lattice alignment.