Researchers developed a fluorescence imaging technique to accurately identify protein receptors in tumors without tissue biopsy. The new approach strongly correlates with clinical immunohistochemistry and may impact oncology patient outcomes.
Research from University of Eastern Finland finds SIP1 protein expression indicates advanced tumour stage, high recurrence risk, and poor prognosis. The study identifies SIP1 as a potential new prognostic factor for clinical use.
Two new studies suggest that smartphones can be a key tool in improving medication adherence among teens and young adults with chronic conditions. Researchers found that patients who used cell phones for reminders were more likely to have 100% self-reported medication adherence, while those involved in a dedicated Young Adult Service h...
The 2014 global ocean warming is a result of North Pacific's record-breaking warming and the release of heat from stored water in the Western tropical Pacific. Temperatures now extend along the North American coast, indicating an end to the 14-year-long pause in ocean warming.
Researchers at the University of Toronto found that personalized dietary advice based on a person's genetic makeup leads to better eating habits and significant reductions in sodium intake. The study, published in PLoS One, suggests that genetic testing can improve lifestyle changes by providing tailored food recommendations.
Researchers at the University of Georgia discovered that chlorogenic acid significantly reduced insulin resistance and fat accumulation in mice fed a high-fat diet. The compound also maintained normal blood sugar levels and healthy liver composition.
Conventional treatments such as surgery and radiotherapy are less effective in prostate cancer patients carrying BRCA mutations, resulting in lower survival rates. The study suggests that targeted therapy, like PARP inhibitors, may be a more suitable option for these patients.
The study using Google Analytics found that online plant databases are visited by users in over 100 countries, with mobile traffic growing steadily. This highlights the democratization of botanical information, equal access for researchers worldwide, and reduced wear on biodiversity objects.
A new smartphone app developed by Rutgers engineers helps Warren Township document and mitigate hundreds of hazards to power lines, reducing the risk of future power outages. The app uses crowdsourcing to gather data from volunteers, which is then presented to utility companies in an organized manner.
A study found that weight loss after bariatric surgery is associated with increased kidney function and decreased albuminuria, a marker of kidney dysfunction. This suggests a beneficial impact on kidney health for patients with and without baseline kidney disease.
The Healthy Heart Score uses data from large-scale studies to estimate an individual's 20-year CVD risk based on nine critical diet and lifestyle factors. The free web-based survey provides practical tips for improving scores by incorporating heart-healthy habits into daily life.
Researchers at the University of Manchester have identified factor H-like protein 1 (FHL-1) as a new target for treating age-related macular degeneration (AMD). The study suggests that insufficient FHL-1 in the eye's back may lead to inflammation and vision loss.
Researchers at the University of Helsinki have uncovered a new regulatory system that senses nutrient deprivation and inhibits growth in fruit flies. This system, which involves protein kinase ERK7, prevents secretion of insulin-like peptides during starvation.
For the first time, clinicians have successfully provided hemodialysis to a patient with Ebola virus disease, resulting in recovery of kidney function. The protocol involved careful measures to maximize safety and minimize risk of secondary transmission, demonstrating that renal replacement therapies can be provided safely.
Glaucoma, affecting over 60 million worldwide, has been linked to mitochondrial gene mutations through DNA sequencing. The research aims to support personalized medicines targeting mutated mitochondria and prevent disease progression.
A study by Mass Eye and Ear found that blast-related ear injuries caused significant morbidity in Boston Marathon bombing survivors. The researchers reported high rates of hearing loss, tinnitus, and dizziness-related quality of life impairment among the patients.
A recent study by University of Leicester researchers found a higher number of fast-food outlets within 500m of inner-city neighbourhoods with high-density non-white ethnic minority groups and socially deprived areas. The study suggests a postcode lottery that increases the risk of developing diabetes or obesity.
A new study from the University of East Anglia finds that a single high level of lithium can cause significant decrease in kidney function, which remains affected for up to nine months. The research emphasizes the importance of regular monitoring, supporting current UK guidelines.
Researchers at UT Southwestern Medical Center found a novel looping mechanism involving DNA end caps that determines gene regulation, contributing to aging and disease. The study reveals how telomere length affects gene expression patterns, potentially influencing the onset of disease and optimizing fitness with age.
A new study reveals a stark assessment of the health dangers faced by male sex workers in Mexico City, with 38% having HIV and 21% having syphilis. The study highlights the need for incentives to promote condom use and improve individual and population health.
Dr. Alford has made significant contributions to health education through his work at Boston University School of Medicine. He received the AMA Award in recognition of his dedication and impact on healthcare education.
A mathematical model predicts that around 10 of 29 people with Ebola are likely to be detected at airport screening when trying to travel from West Africa to the UK and US by the end of the year.
A study of 699 African American adults found that those with severe periodontal disease developed chronic kidney disease at a rate 4 times higher than those without. Targeting periodontal disease may be an important path towards reducing disparities in chronic and end-stage kidney disease.
Researchers created a three-dimensional model of a single neuron to study its electrical properties. The study found that changes in cell morphology affect hyper-excitability, highlighting a new relationship between cellular dysfunction and structural integrity.
Youngsters with diabetes are more inclined to perform tasks related to their condition when prompted by a friendly interactive robot. The ALIZ-E project has shown that social robots can assist children with other medical conditions and act as classroom assistants, improving learning outcomes.
A position paper by ESPGHAN Hepatology Committee outlines recommendations and a checklist for liver biopsy in infants and children. Liver biopsy is still necessary in follow-up after liver transplantation and for monitoring disease activity.
A new study found that teen drivers who start class earlier in the morning are involved in significantly more motor vehicle accidents. The results suggest that early high school start times contribute to teens' reduced sleep and increased risk of drowsy driving accidents, including run-off-road crashes.
Researchers developed a method to securely display 3D images on smartphones by scanning QR codes without accessing the Internet. The system uses integral imaging and encryption to protect data, ensuring only authorized devices can access the content.
Scientists found 12 caves with trechine beetles, 7 new species, and 103 samples collected, highlighting the Du'an Karst as a biological hotspot for cavernicolous Trechinae in China.
Researchers at University of Guelph found a potential breakthrough in treating late-stage ovarian cancer by shrinking tumours and improving drug delivery. This approach may lead to novel treatment options with reduced morbidity and mortality.
A new international study led by the Research Institute of McGill University Health Centre has identified a molecule that puts a brake on brain processing and when removed, brain function and memory recall are improved. The study found that suppressing the production of molecules required for building new memories leads to stronger con...
Researchers at Lund University have identified a mechanism that creates cold-induced pain, linking it to the same receptor that reacts to pungent substances in mustard and garlic. This discovery could help those with cold allodynia, a common problem among patients with chronic pain or nervous system diseases.
Researchers have developed a new method to predict illegal fishing patterns in offshore marine reserves, enabling authorities to better protect these areas. The study, which analyzed data from the Cocos Island National Park, identified hotspots and lunar phases associated with illegal fishing, allowing for more targeted patrols.
Astronomers find compact, young galaxies shut down their prodigious star production due to a lack of cool dense gas, rather than supermassive black holes. The energy from the star formation itself creates a shortage of gas within the galaxy.
Researchers found high genetic diversity in thousand cankers disease fungus, making it harder to control. The fungus is native to the US and has mutated readily, leading to an explosion in its impact on host trees.
A research project has been awarded for its innovative approach to stopping bone destruction and tooth loss in severe gum disease. The study aims to re-programme the immune system to fight bacteria without damaging healthy tissue, thereby halting bone destruction before it advances.
Scientists have found that self-doping in the copper-based material YBCO enables it to conduct electricity without loss at room temperature. This groundbreaking discovery challenges traditional understanding of high-temperature superconductivity and could pave the way for more efficient electrical applications.
A recent study found that feelings of disgust can increase behaviors like lying and cheating, while cleanliness can help people return to ethical behavior. The researchers used three randomized experiments to test the impact of emotions on decision-making.
Researchers at Sentient Science and University at Buffalo develop wearable technology to measure stress, fatigue, and resilience. The system sends personalized alerts to prevent heart attacks and physical injuries.
Researchers discovered a plant protein, KEA3, crucial for adjusting photosynthetic efficiency in fluctuating light conditions. This mechanism enables plants to quickly respond to changes in light intensity and maintain high energy capture.
Smoking increases susceptibility to TB infection, with white blood cells in smokers' lungs showing a weakened response to the disease. The discovery provides new insights into treating and preventing TB, which kills 1.5 million people annually.
The Ebola pandemic serves as a stark reminder of the interconnectedness of human, animal, and environmental health. The study emphasizes the urgent need to adopt a One Health approach to detect and prevent infectious diseases, particularly in developing countries.
Researchers created a global model of CO2 uptake using fine-scale observations, finding strong interannual variations and the Pacific Ocean dominating flux variability. The study's lead author notes that shipboard measurements provide key data for estimating ocean CO2 sink variability.
Bio-inspired bleeding control is achieved through the synthesis of platelet-like nanoparticles that mimic the human body's own coagulation processes. These tiny particles can be added to blood flow to supply or augment the patient's natural platelet supply, stemming bleeding and initiating healing.
Researchers are developing AI-powered software to automatically outline bones in X-ray images, a system that can already identify hips and will now be adapted to map out knees and hands. The goal is to reduce the workload of human researchers and enable faster diagnosis for patients with conditions like arthritis.
A new study published in JAMA Ophthalmology found that telemedicine screening detected diabetic retinopathy in approximately 21.7% of the participants, highlighting its potential as a critical tool for patients with diabetes who face barriers to accessing regular eye care.
A new study from Harvard Medical School reveals that genetic variants control DNA replication timing, varying among people. This variation affects mutation rates and individual disease risk, including blood cancers.
Research finds that the Darrington-Devils Mountain fault zone is prone to strong earthquakes, with evidence of a M 6.7 to 7.0 quake 2,000 years ago and another at 8,000 years old. This suggests a right-lateral slip sense during past earthquakes, which may be related to ongoing clockwise rotation in the region.
A new study suggests that individuals with more severe asthma may be more motivated to lose weight, making them a key target for intervention. Gender tailoring of weight loss programs could also enhance success rates among adults with asthma.
Researchers at the University of Houston have developed a molecule that can capture potent greenhouse gases, including Freons and fluorocarbons. The molecule's lightweight structure with microscopic pores makes it an attractive solution for capturing large quantities of greenhouse gases.
Researchers discovered that simvastatin inhibits the growth of uterine fibroid tumors, which are responsible for half of all hysterectomies. The study found that simvastatin impedes cell growth and induces calcium-dependent cell death mechanisms in fibroid tumor cells.
A new study using coral samples from a remote Pacific island in Kiribati reveals the ocean has warmed over the last sixty years, priming it for stronger El Niáo events. This warming trend could have a major impact on Australia's weather, particularly during El Niáo events when warm waters move eastward and bring droughts.
Researchers at Morgridge Institute for Research discovered a method to impose an immortal-like state on mouse progenitor cells responsible for producing blood and vascular tissue. The breakthrough enables the creation of functional endothelial, blood, and smooth muscle cells, paving the way for cell-based therapies and drug screening.
The Thirty Meter Telescope has launched the THINK Fund, a $1 million annual initiative to support Hawaii Island students in STEM disciplines. The fund will provide scholarships and grants for STEM education initiatives, with a focus on improving opportunities for Native Hawaiian students.
A recent investigation explored whether Facebook murders were unique and worthy of a new label. The study found that these crimes followed typical patterns, with victims knowing their killers, and social media played no more significant role than other tools in the commission of violence.
A study using mathematical models shows that genetic testing can substantially improve breast cancer prevention by analyzing multiple gene variants. The research suggests that combining genetic data with other risk factors can identify the most at-risk women, who account for 32.2% of all breast cancer cases.
Research reveals that Enterotoxigenic E. coli (ETEC) strains infecting adults and children globally have similar toxins and virulence factors, indicating potential for a single, effective vaccine.
Researchers at Rutgers University have developed a platform called NanoScript, which can interact with endogenous DNA and regulate gene expression. This technology has great potential for advancing stem cell therapeutics and treating debilitating injuries and diseases such as Parkinson's disease and spinal cord trauma.
A new multi-center study has confirmed that specific gene variants in African American kidney donors are associated with a higher risk of organ failure after transplantation. The findings suggest that rapidly genotyping deceased donors for these variants could help inform organ allocation and consent processes.
The study reveals that cooperation emerges when individuals assemble into groups that interact through repeated Public Goods Games. The authors propose an evolutionary game theory model, which suggests a large set of possible responses depending on previous levels of group cooperation. Ultimately, the most successful strategy is 'All-o...