A computer model predicts significant changes in the Ross Sea ecosystem, including disruptions in food webs and predator-prey relationships. Rising temperatures and changing wind patterns are expected to affect biological productivity and species distributions.
Scientists at Scripps Research Institute developed a method to modify organic molecules, expanding possibilities for new pharmaceuticals and improving old ones. The innovation makes it easier to attach biologically active functional groups to drug molecules.
Researchers from the University of Pittsburgh and Brandeis University have provided experimental evidence validating Alan Turing's theory of morphogenesis in cell-like structures. The study confirms the prediction of six different patterns and discovers a seventh, demonstrating how identical biological cells differentiate into distinct...
A University of Calgary-led study has found that the majority of sand in Alberta's oilsands came from the Appalachian region on eastern North America. Researchers used a technique called detrital zircon uranium-lead geochronology to determine the age of individual sediment grains, revealing a range of ages from 300 to 2,800 million yea...
Researchers analyzed the genomes of 767 individuals for single nucleotide polymorphisms (SNP) to identify genetic loci related to musical aptitude. The study found associations with genes involved in inner-ear development, auditory pathways, and emotional processing.
Researchers used a nerve growth factor-containing fibrin glue membrane to bridge a sciatic nerve defect, significantly increasing mRNA and protein expression of p75NTR in Schwann cells. This promotes peripheral nerve regeneration.
Researchers found that emotional stressors like anger can cause changes in the nervous system controlling heart rate, triggering microvascular coronary dysfunction more often in women than men. This condition can lead to heart attacks and other cardiac issues despite clear arteries.
A new study found that 21% of transgender people avoid EDs due to fear of negative experiences. Trans-specific negative experiences reported include refusal of care or examination in alignment with their felt/core gender. This highlights the need for better training and safe environments within EDs.
The BRCA1 gene is expressed in skeletal muscle cells and plays a critical role in fat storage, insulin response, and mitochondrial function. Mutations in the BRCA1 gene may increase the risk of metabolic diseases like obesity and type 2 diabetes.
Researchers at North Carolina State University have developed a new trial design to counter the caregiver placebo effect in veterinary medicine. The study found that a low-dose pain medication was effective in cats with degenerative joint disease, despite owners' initial perceptions of improvement due to the placebo effect.
Researchers found that purified fish oils improved blood sugar levels in babies with congenital hyperinsulinism. The treatment, combined with standard medical care, has the potential to stabilize blood sugar levels and prevent long-term disabilities.
Scientists at Purdue University have successfully created a new type of ultracold molecule using lasers, which could enable quantum computing, precise sensors, and advanced simulations. The lithium-rubidium molecule has a significant dipole moment, enabling stronger interactions necessary for entanglement-based quantum computing.
A University of Alberta team has discovered a water-rich mineral called ringwoodite, containing 1.5% water by weight, deep beneath the Earth's crust. This finding confirms scientific theories about massive volumes of water trapped between 410-660 km below the surface.
Tropical Cyclone Lusi intensified to hurricane force near Vanuatu, bringing heavy rain, thunderstorms, and potential flooding. The storm is expected to weaken on March 13 before transitioning into an extra-tropical storm.
Researchers at EPFL have developed a promising antibiotic, PBTZ169, effective against multi-resistant strains of tuberculosis. The IM4TB Foundation will bring the new treatment to market, addressing limitations in industrial model development costs and accessibility.
A rare metabolic disease causing liver failure and autistic behavior showed significant improvements after a liver transplant, suggesting an unexpected link between metabolic conditions and some forms of autism. The patient's normalization of cholesterol levels after transplantation halted the progression of neurological damage.
Researchers from UCLA have updated guidelines for managing skin abscesses associated with community-acquired MRSA. The new guidelines focus on improving diagnostic accuracy and treatment options, including the use of ultrasound and preferred antibiotics like trimethoprim-sulfamethoxazole and doxycycline.
A large waist circumference is associated with increased mortality risk, even among individuals with a healthy body mass index (BMI). Men and women with larger waists are more likely to die younger and die from illnesses such as heart disease and cancer. Researchers recommend considering both BMI and waist circumference in risk assessm...
Researchers identified DNA methylation changes in the HIF3A gene that correlate with BMI and increase the risk of diseases like diabetes. The study suggests a new potential target for treating obesity-related health issues.
A study found that children with autism spectrum disorders and attention deficit hyperactivity disorder are 7.59 times and 6.64 times more likely to express gender variance than their peers without these conditions. Participants with gender variance also experienced elevated anxiety and depression symptoms, but to a lesser extent among...
A Concordia University study found that maintaining or improving self-esteem can help prevent health problems in seniors. The research team measured cortisol levels, self-esteem, stress, and symptoms of depression in 147 adults aged 60 and over, revealing a strong association between declining self-esteem and increased cortisol levels.
Researchers at North Carolina State University discovered that altering the surface characteristics of a semiconductor material can significantly impact how neural cells grow. The study used gallium nitride and PC12 cells to mimic neural behavior, finding varying degrees of cell adhesion and growth on different textured surfaces.
Chronic pain researchers found that individuals with chronic tension-type headache exhibited impaired neuroplasticity, affecting their brain's ability to change and adapt. This discovery could lead to more targeted treatments for patients.
Researchers found that up to 1,750 euros in income has a positive correlation with happiness, but after this amount, the co-relation becomes negative. Maintaining work stability and reducing working hours can have a positive impact on wellbeing.
A recent study from the University of California, Davis, found that the hippocampus stores memories based on their temporal context, which includes what happened before and after an event. This means that the brain uses context to represent specific objects, rather than just their content.
The Ground Validation program gathers similar precipitation data on the ground to compare with satellite data, improving models and understanding precipitation physics. Remote campaigns and a Precipitation Science Research Facility supplement GPM data, allowing scientists to monitor precipitation under various conditions.
Researchers have discovered detrital pyrite and uraninite grains in sedimentary rocks, which constrain the rise of oxygen to younger than 2.415 billion years ago. A new model also reveals an ancient atmosphere with less than ~10^-5 atm of O2 at 2.4 billion years ago.
A recent study by IIASA researchers found that education significantly improves cognitive function in seniors and slows down cognitive decline. The study examined variation in years of schooling in six European countries during the 1950s and 1960s and showed that compulsory educational reforms had a positive impact on mental functioning.
A massive earthquake triggered a global 'stress shadow' where nearly all potential faults remained inactive for 95 days. This rare phenomenon suggests that large quakes can temporarily relieve stress on nearby faults.
A new gene therapy approach has been shown to be safe and well-tolerated in a clinical trial of four children with mucopolysaccharidosis type IIIA, an inherited lysosomal storage disease. The treatment involved delivering therapeutic genes via an adeno-associated viral vector, resulting in improved brain shrinkage and behavioral changes.
A study found that postoperative 'doctor shopping' is associated with longer narcotic use and more prescriptions among orthopaedic trauma patients. The researchers discovered a strong link between preoperative narcotic use and increased doctor shopping behavior.
A new cell type has been identified as a contributing factor to post-traumatic epilepsy caused by traumatic brain injury. The study found that damage to interneurons disrupts neurotransmitter levels, leading to increased epileptic activity.
A recent study published in Nature Communications has identified two new gene regions linked to bipolar disorder, bringing hope for new treatments. The research, involving over 24,000 patients and healthy individuals, sheds light on the genetic factors contributing to the complex condition.
A Yale University analysis found nearly all clinical trials had discrepancies between reported results and published articles. The study suggests errors in reporting or intentional changes may have occurred. Accurate reporting is crucial for maintaining trial integrity.
Tropical Cyclone Gillian's center remained over land on March 11 with maximum sustained winds near 35 knots/40mph. NASA's TRMM satellite detected powerful storms up to 16km high, indicating significant power before the cyclone made landfall.
Researchers at Monash University developed a new class of drug targeting alternative recognition sites on GPCRs to fine-tune protein behavior, reducing damage and potential side effects. The breakthrough could lead to the creation of a new treatment for heart attacks and heart failure.
A new study published in the Journal of Consumer Research found that brands can act as a replacement source of emotional attachment when a person-to-person support system is not available. Researchers discovered that exposure to fear can increase positive emotional brand attachment, leading to stronger consumer connections with brands.
A study by University of Pittsburgh researcher Susan Kalisz found that high deer densities are the primary reason for garlic mustard's takeover in native plant species, such as trillium. By excluding deer, native plants can repel invaders and increase their populations.
Researchers at Henry Ford Hospital found that the peptide AcSDKP provides neurological protection when administered after a stroke, reducing neurovascular damage and improving outcomes. The study also showed that combining AcSDKP with tPA extended the therapeutic window for up to four hours after stroke.
A study found nearly all clinical trials had at least one discrepancy in the study group, intervention, or results reported on ClinicalTrials.gov versus high-impact journals. Discrepancies included primary end points, dosages, and frequencies of interventions.
Researchers have found a potential new treatment for patients with advanced melanoma and kidney cancer. The study used an antibody that targets the tumor-enhancing protein TGFβ, which is involved in cell growth and spread of tumors.
Tropical Cyclone Hadi weakened to depression status, while Tropical Cyclone Lusi strengthened with maximum sustained winds near 50 knots/57.5 mph/92.6 kph. NASA's Aqua and TRMM satellites provided crucial rainfall data, cloud heights, and temperature information.
Researchers documented dramatic differences in swimming ability between domesticated and wild trout, calling into question the effectiveness of hatcheries in conserving native populations. The study found that domesticated trout tend to grow faster but are slower sprinters than their wild relatives.
Surgeons in France have successfully replaced aortic valves without opening the chest in two patients. This innovative technique, known as TEAVR, shows promise for improving quality of life by reducing chest trauma and enabling faster recovery times.
A clinical trial identified women most likely to benefit from vaginal mesh surgery for vaginal prolapse, specifically those with levator avulsion. The study found that patients with this condition had a higher risk of recurrence after sacrospinous vaginal colpopexy, making vaginal mesh implantation a viable alternative.
Researchers compared two common surgery procedures for vaginal prolapse and stress urinary incontinence. The study found no significant difference in functional or adverse event outcomes between sacrospinous ligament fixation and uterosacral ligament vaginal vault suspension surgeries.
Researchers developed an MRI that can visualize bone and soft tissue despite the presence of metal screws, allowing for earlier detection of osteonecrosis. The study found that 80% of patients had decreased blood flow to the injured area and osteonecrosis in the femoral head.
A framework for improved geriatric patient care is proposed based on lessons learned from managing complex care transitions. The framework emphasizes the importance of looking at community, system and regional factors in care transitions.
SURA honors Dr. Jeffrey Skolnick, a renowned biologist at Georgia Tech, for his groundbreaking research on protein structure and function. His cutting-edge discoveries have the potential to dramatically accelerate and enhance the drug discovery process.
A neuroimaging study found that adolescents with antisocial personality disorder have reduced activation in brain regions responsible for social information processing and impulse control. This impairment leads to difficulties in taking into account other people's intentions, resulting in more antisocial behavior.
Research at the University of Copenhagen reveals that cosmetic fillers can act as incubators for bacterial infection, causing lesions and tough film-like material resistant to antibiotics. Prophylactic antibiotic treatment during procedures can prevent these complications.
A study found that total joint replacement (TJR) reduces the risk of heart attack, stroke, or other 'cardiovascular events' in patients with moderate-to-severe arthritis. This may be due to increased mobility and physical activity levels, which have a positive impact on cardiovascular health.
Researchers at St. Michael's Hospital found that ultrasound-guided paravertebral blocks improved pain relief, reduced recovery room time, and enabled earlier discharge for breast cancer patients compared to general anesthesia. The study's lead author notes the benefits of this technique will also apply to cosmetic breast surgeries.
The Rowan Venture Fund will provide seed money for research ideas, accelerating growth and innovation at the university. With a focus on engineering, medical education, health sciences, and business, the fund aims to commercialize technologies and invest in startups.
Researchers at Helmholtz Munich have found that GAD antibody affinity is a key indicator of LADA disease progression. The study used GAD vaccination to examine the impact on antibody affinity in 46 LADA patients, finding no influence from vaccination. Patients with high affinity had low insulin production and required insulin therapy s...
A new study suggests that feeling sad can decrease cravings for unhealthy foods like chocolate and deep-fried treats. By making individuals feel sad, their negative emotional response to these foods highlights the potential health risks associated with overindulgence, leading them to make healthier choices.
A recent study found that light pollution impedes fruit-eating bats from dispersing seeds, which is crucial for tropical forest regeneration. As a result, seed rain is reduced, threatening the natural succession of forests in illuminated habitats.
Research reviewed injuries in top Italian football league during 2011-2012 season, finding 23 injuries on artificial turf and 20 on grass. Muscle strains were the most common injury on both surfaces, with only minor differences between their causes.
A University of Iowa-led study found that adding healthy foods to concession stands can increase sales and profits while maintaining customer satisfaction. The study, which involved a school booster club in Muscatine, Iowa, showed that introducing healthier options led to stable sales and revenue increases.
Approximately 25 percent of randomized clinical trials were discontinued between 2000 and 2003, mainly due to poor recruitment, with only 38 percent reported to research ethics committees. Discontinued trials were less likely to be published, especially those sponsored by industry.