Researchers at Barrow Neurological Institute and TGen will analyze blood and CSF samples from 60 participants to identify peptide, protein, and RNA biomarkers indicative of ALS progression. The goal is to develop effective treatments for patients in clinical trials.
The OU School of Aerospace and Mechanical Engineering has been selected for a national diversity program to close the gender and minority gap in mechanical engineering. The school will receive education and training on diversity and inclusion to attract and retain underrepresented students and faculty.
The 1000 Genomes Project has completed an unprecedented analysis of human genetic variation, providing a comprehensive resource for researchers. The project identified 136 candidates related to diseases, including cancer, and found a cluster of variants involved in successful pregnancy completion.
Dr. Sharon K. Inouye has received the 2015 M. Powell Lawton Award from the Gerontological Society of America (GSA) for her significant contributions to gerontology. Her work focuses on delirium prevention and treatment, and she has developed evidence-based interventions such as the Hospital Elder Life Program (HELP), which has been sho...
A study by Helmholtz Munich found that lung cancer patients incur an average of €20,000 in costs over three years. Surgery proved to be the most cost-effective treatment option, while chemotherapy and radiation therapy were more expensive.
A study published in Archives of Physical Medicine & Rehabilitation found that living in areas with greater mixed land use was associated with poorer perceived health among New Jersey residents with spinal cord injury. This contrasts with general population studies, which suggest benefits from more populated areas with mixed land use.
Opioid misuse is a major burden on the European drug treatment system, with a decline in new heroin treatment clients since 2007. Drug injection remains a key driver of HIV transmission and overdose deaths, particularly among older users. New psychoactive substances are increasingly reported, posing a growing concern for public health.
Researchers measured radioactivity in infant formulas worldwide and found higher doses than reported limits but lower than recommended levels. Factors such as soil and raw material radioactivity affected levels, highlighting the need for improved monitoring.
Researchers used single-cell RNA sequencing technology to study gene expression in mouse embryonic stem cells, identifying new genes involved in pluripotency and discovering new subpopulations of cells. The findings provide insights into the links between environment and inter-cell heterogeneity.
KW-0761 efficiently eliminates Tregs from the blood of patients with lung or esophageal cancer, potentially augmenting the natural anticancer immune response. The study found a modest induction of antitumor immune responses and no marked clinical responses in patients treated with KW-0761 monotherapy.
A Mayo Clinic study found that genetic differences among races affect colon cancer recurrence. Tumors from whites were twice as likely to have BRAF mutations, while black tumors had the highest frequency of KRAS mutations, leading to a higher risk of recurrence among young blacks.
A new tropical storm, named Kabayan, has formed off the Philippines and is moving towards the country. The Joint Typhoon Warning Center predicts the storm will make a final landfall in southeastern China on October 4.
A new material with extremely long polymer chains has been developed to reduce fuel misting and consequential explosiveness. The polymers can break apart when sheared during flow but reassemble into super-long chains needed to prevent misting, resulting in significant reductions in misting and explosiveness.
A new US Forest Service-led study reveals that habitat diversity is key to protecting coastal cutthroat trout from the effects of forest harvest and climate change. The study found that trout in different streams respond differently to these disturbances based on their habitat features.
Researchers discovered a molecular switch that balances the activity of two key proteins in the circadian clock, PER2 and CK1. This finding provides insights into familial advanced sleep phase disorder (FASP) and may lead to new treatment strategies using drugs that inhibit these proteins.
A new study finds that going to bed late during adolescence is associated with an increase in body mass index over time. Researchers analyzed data from over 3,000 participants and found a significant link between later bedtimes and higher BMI. The study highlights the importance of adolescent bedtime habits in weight management.
A new study by the American Sociological Association found that men dominate media coverage due to their representation in leadership positions and the lack of female representation in these roles. The study analyzed data from over 2,000 US newspapers and magazines from 1983-2009.
A study by UCSB and NASA reveals that humans are inherently bad at watching computers work, with distractions and daydreaming leading to failures in practical monitoring tasks. Pilots missed 25% of altitude crossings despite high levels of cockpit automation, highlighting the challenges of task monitoring.
In Trinidad and Tobago, ballistic imaging technology was hindered by inefficient processes, backlogs, and delayed information transmission. The country's Integrated Ballistics Information System (IBIS) generated few hits due to database delays and insufficient evidence input.
A new report by IOP Publishing and Research Information Network (RIN) analyzes the changing information practices of physical scientists, with 70% collaborating with researchers outside their department in the last five years. Researchers prefer building personal collections of research articles, with 87% storing electronically.
A new study from the University of California, Berkeley found that teenagers who go to bed late on weeknights are more likely to gain weight than their peers who hit the hay earlier. For every hour of sleep lost, participants gained 2.1 points on the BMI index over a five-year period.
The USC Viterbi School of Engineering Center has been awarded an $8 million grant under the White House Materials Genome Initiative to develop new nanomaterials. The center will use open-source software, experimental data, and immersive visualizations to accelerate innovation in materials science.
A EU-funded project led by the University of Huddersfield is empowering community-managed forest areas in Ethiopia, improving local livelihoods while protecting biodiversity. The project's Participatory Forest Management approach has enabled over 55 village communities to manage large forest areas.
A study from the University of Waterloo found that climate change proponents use more cautious language to report on the science, while skeptics use more emotional and assertive language when interpreting studies. This suggests that political context plays a role in shaping scientists' communication style.
New evidence suggests that a massive asteroid collision with Earth triggered increased volcanic activity in the Deccan region of India. High-resolution argon dating revealed a dramatic increase in eruption rate within 50,000 years of the impact.
The number of statistics graduates has increased by 300% since the 1990s, with bachelor's degrees growing 17% from 2013 to 2014. Demand for statisticians is expected to outpace growth, with a potential shortage of 140,000 workers with deep analytical skills by 2018.
Researchers at Caltech have developed a polymeric fuel additive that reduces the intensity of postimpact explosions in jet engines, without affecting fuel performance. The additive works by inhibiting droplet breakup under impact conditions, thereby reducing explosion size and turbulence.
A study from the University of Eastern Finland found that infrared thermography can detect joint inflammation in ankle joints, but not knee joints. The technique also showed potential in evaluating office ergonomics and assessing musculoskeletal conditions, which could ease the workload in specialized healthcare and reduce costs.
Infants diagnosed with neonatal abstinence syndrome (NAS) are at increased risk for hospital readmission, particularly due to withdrawal symptoms. The study suggests that families of infants with NAS may benefit from additional post-discharge resources to mitigate this risk.
Scientists have discovered that brain cells contain significant numbers of somatic mutations, which contribute to human development and disease. The study provides a new perspective on the role of these post-conception mutations in shaping brain cell lineages and potentially driving neurodegenerative disorders.
Scientists have developed a new method to analyze the movement of specific atoms in dielectric materials when exposed to an electric field. This technique uses X-rays and advanced mathematical analysis to determine changes in atomic placement within the crystalline structure of the material.
A new study published in Limnology and Oceanography found that a nutrient-rich, balanced diet is beneficial to corals during stressful thermal events. The researchers discovered that excess nitrogen alone and zooplankton made high-temperature bleaching events worse, while a balanced mix of nutrients afforded coral resilience.
Carnegie Mellon University has established an analytics lab with Boeing to develop AI-powered solutions for aerospace data. The lab aims to capitalize on the vast amounts of data generated in aircraft design, construction, and operation, enabling safer, more reliable, and efficient aircraft operations.
Researchers at Uppsala University have developed an anti-aging treatment for smart windows by rejuvenating electrochromic layers, reducing their lifespan. The new method could also be applied to electric batteries, making them more profitable.
A recent study by Mark Dingemanse and colleagues reveals that language is less arbitrary than previously thought. The researchers found that iconicity, where word forms suggest meaning, and systematicity, a statistical relationship between sounds and grammatical usage, complement arbitrariness in vocabulary structure.
A new study has identified specific genes that are repressed after memory formation, providing insights into how long-term memories are formed. The researchers found that estrogen receptor alpha (ESR1) and Nrsn1 genes play a crucial role in modulating gene-regulatory networks after learning.
Research at Boston Children's Hospital identifies IGFBP3 as the hormone destroying intestinal stem cells in type 1 diabetes, leading to a potential treatment strategy with TMEM219. The study also suggests a new approach to cell therapy by exploiting hormones controlling stem cell production.
Researchers at the University of Georgia found that the same genetic tools responsible for limb development in animals also control the formation of external genitalia in snakes. The study suggests that snakes retained DNA associated with limb development through millions of generations, as it may have been important for their reproduc...
A recent study found that approximately 43% of the S-equol in women's plasma is in two biologically active forms after ingestion. These findings suggest that these bioactive forms may contribute to the relief of menopausal symptoms, as reported in previous clinical trials.
Researchers have discovered a new molecular marker for killer cells, allowing for the prediction of infection course. The marker, CX3CR1 receptor, is associated with chronic infections, where immune system effectiveness is compromised.
Dental researchers at Plymouth University have won several prestigious awards, including the Unilever poster prize and a commendation in the Senior Colgate competition. The university's strong research culture was also recognized, with a notable increase in attention from dental research experts.
Researchers discovered genetic alterations in healthy breast cells associated with an increased risk of non-familial breast cancer. These findings can be used for future improvements in diagnostics to identify women at high risk before the tumor forms.
Katie Maslow, MSW, of the Institute of Medicine, has been chosen as the 2015 recipient of the Maxwell A. Pollack Award for Productive Aging. She will receive the award for her innovative programs that demonstrate excellence in translating research into practical application or policy.
Researchers have found that snakes share similar genetic patterns with mammals and birds in their limbs and genitalia, suggesting a common ancestry. The study's findings suggest that these genetic elements may play a crucial role in phallus development and genital shape variation among species.
New evidence shows that asteroid impact on Earth 66 million years ago accelerated volcanic eruptions in India for hundreds of thousands of years. The eruptions, known as the Deccan Traps, likely suppressed recovery of life for 500,000 years after the KT boundary.
Researchers at EPFL have created a groundbreaking DNA stain called SiR-Hoechst, which enables the safe imaging of living cells for extended periods. This innovation allows biologists to track biological processes such as cell division in real-time, paving the way for further breakthroughs in bioimaging.
A University of Chicago team aims to establish a new system of diagnosis for psychotic diseases using biomarkers, which may guide the development of novel therapies. The Bipolar-Schizophrenia Network on Intermediate Phenotypes will recruit additional study participants over five years.
A Phase 2 clinical trial found that gene therapy VB-111 increased overall survival to 15 months, compared to 8 months for those receiving chemotherapy Avastin alone. The therapy effectively starves tumors by blocking new blood vessel growth and is safe and well-tolerated.
Researchers at Children's Hospital Los Angeles have successfully engineered a colon from human cells that develops various types of neurons. The study has shown that these specialized neurons can be supplied to tissue-engineered colon, mimicking the enteric nervous system found in native colon.
Researchers have created a new investigational drug that traps IGFBP3, preventing gastrointestinal symptoms and restoring the intestine's mucosal lining structure. The drug may hold promise as a potential treatment for diabetic enteropathy, a common complication of type 1 diabetes.
A study found that bariatric surgery slashed participants' weight by a third and eliminated precancerous uterine growths in those that had them. It also improved insulin levels and glucose use, altering the composition of gut bacteria.
Researchers found the fossil record of the earliest North American coral species that reappeared after a mass extinction event, providing insights into survival and recovery. The study reveals that corals took over 20 million years to recover from the event, which was likely caused by massive global climate change.
GABA's role in dampening hyperactivity has led researchers to believe that increased production during adolescence improves symptoms for the majority of people with TS. This finding could offer a new approach to treatments targeting GABA levels in brain areas controlling motor function.
Researchers have discovered a new approach to understanding cancer mechanisms, biomarkers, and treatments using RNA editing events. The study, published in Cancer Cell, found that specific RNA editing processes could selectively affect drug sensitivity and may lead to the development of targeted therapies.
A study of 1.17 million patients on dialysis found that tallness was associated with higher premature mortality risk and shorter life spans, especially in white, Asian, and American Indian/Alaskan native patients. The association persisted even after adjusting for concurrent illness and care differences.
A team of researchers found specific variations in RNA splicing that may play a role in converting normal breast cells into tumors. The study identifies potential targets for therapies in some forms of breast cancer.
A new guide developed by FAU's College of Nursing aims to improve communication and decision-making for nursing home residents and their families. The guide provides evidence-based information on treatment options, health conditions, and the risks associated with hospitalization.
A study on migrating pike in the Baltic Sea found that accurate timing is crucial for survival and that fine-tuning behavior improves life expectancy. The research showed that individuals who adjust their migration timing based on experience have higher life expectancies than those who do not.,
A review article in Trends in Microbiology reveals that microbial invasions follow a general ecological pattern, with invasion phases including introduction, establishment, spread, and impact. The study found that species diversity is the best defense against invading microbes.
Researchers found that people's aesthetic preferences for faces agree about 50% and disagree about 50% with others. Personal experiences, such as those with friends or media, play a significant role in shaping individual face preferences, according to the study published in Current Biology.