Indiana University researchers found that restoring missing microRNA-29 in pancreatic cancer stromal cells reduced the viability and growth of cancerous cells. The study suggests that miR-29 could be a potent therapeutic agent against pancreatic cancer by targeting reactive tumor stroma.
A recent Cornell Food & Brand Lab study found that serving vegetables at dinner increases the perception of being a better cook and a more loving parent. Serving veggies even if not liked can make the meal tastier, according to lead author Brian Wansink.
Despite fewer legal barriers, women in developed countries still face significant inequities in abortion access due to inadequate service provision, moral opposition, and inadequate training. The review suggests improving access by increasing training, boosting service options, and making services more affordable or free.
Researchers found that up to 20% of a mosquito population's genome is subject to evolutionary pressures, leading to local adaptation and potential resistance to pesticides. The study provides insights into the contemporary evolution of mosquitoes and informs strategies to control populations.
A small pilot study found an experimental treatment approach can send deadly leukemia into remission in patients who have failed standard therapy. The combination of immunotherapy and gene manipulation buys critical time for patients to receive a potentially life-saving stem cell transplant.
A study by University of Basel researchers found that fructose stimulates the reward system in the brain to a lesser degree than glucose, leading to increased satiety hormone levels and reduced feelings of fullness. This may contribute to the development of various disorders such as obesity, diabetes, and fatty liver disease.
A University of Kentucky researcher is developing an artificial blood technology for mosquitoes, which can help sustain colonies in resource-limited areas and combat diseases like malaria. The approach involves sterilizing mosquitoes using a bacterium and has already shown promising results in controlling Asian tiger mosquito populations.
Researchers monitored Helheim Glacier for 55 days and detected 10 large-scale calving events, revealing unique quakes registering magnitude five on the Richter Scale. These glacial earthquakes can serve as proxies for glacier edge breaking, offering insights into ice loss from glaciers.
Researchers from top institutions emphasize the need for high-quality science by addressing issues such as replication problems, researcher misconduct, and sensationalism. They propose solutions like rewarding quality work, mentoring peer-reviewers, and voluntary withdrawal of flawed papers.
A University of Toronto study found that augmented-reality displays on windshields can reduce driving accuracy and increase the risk of accidents. Drivers must divide their attention between road conditions and digital warnings, leading to slower reaction times and missed warnings.
A new pilot study found that Montmorency tart cherry juice reduced upper respiratory tract symptoms in marathon runners. The study also showed lower markers for inflammation compared to a placebo group. This research provides encouraging evidence of the potential role of tart cherries in reducing exercise-induced respiratory problems.
A new INFORMS journal study provides more predictable ways to manage arrival traffic at airports with adverse weather. The research reveals that knowing early about late flights reduces the cost of Ground Delay Programs (GDPs) for flight operators, with a 13% reduction in delays observed.
A new study reveals that heat-tolerant corals can pass on their tolerance genes to their offspring, potentially helping reefs adapt to global warming. The research found that coral larvae from hotter regions were more likely to survive in warmer conditions than those from cooler regions.
Researchers found that early-age exercise in mice had positive effects on adult levels of voluntary exercise, including a reduction in body mass. The study suggests that early-life exercise may increase the likelihood of adults engaging in regular physical activity.
A new study by the U.S. Geological Survey and Florida Atlantic University reveals that past water conditions and availability are crucial factors affecting wading bird populations in the Everglades. The research found a 'lag effect' where wet conditions can take several years to impact bird numbers.
Researchers at UC Davis and the University of Delaware discovered that chloroplast tubes play a key role in plants' immune defense. The discovery reveals how chloroplasts deliver signals to the nucleus, inducing programmed cell death and preparing other cells to resist infection.
A five-session intervention teaches social and emotional competencies to reduce sibling conflict. Moms report improved emotion regulation after watching sessions and coaching their kids. Fathers also show reduced negative emotions when children's conflicts decrease.
A pilot program at a pediatric long-term care facility achieved significant reductions in antibiotic use, with a 59% decrease in topical antibiotics and an 83% decrease in orders without proper documentation. The program improved antibiotic prescribing practices through increased staff support and electronic medical record system changes.
Researchers discovered a way to suppress nonlinear distortions in optical fibers, eliminating signal regeneration needs. This breakthrough enables more bandwidth availability and increased data transmission.
Researchers found that the KaiC protein encodes the Earth's 24-hour rotation period at an atomic level. The protein's structure and reactivity regulate molecular rhythms, which could lead to new therapies for circadian rhythm disorders.
A computational model predicts the development and progression of pressure ulcers in spinal cord injury patients. The model validated by virtual clinical trials shows that anti-inflammatory measures must be applied early to prevent ulcer formation.
Researchers argue that current diagnosis methods for depression are flawed and that understanding 'normal' emotional responses can help inform clinical practice. Increased interaction between fundamental emotion research and practitioner training is necessary to ensure accurate diagnosis and treatment of emotional disorders.
Researchers developed targeted nanoparticles that deliver existing drugs directly into parasite cells, reducing the curative dose by 100-fold and circumventing drug resistance. This high-tech approach has the potential to reverse resistance to many first-line treatments for infectious diseases.
Researchers at UNC School of Medicine have developed an experimental gene transfer-based treatment to deliver a missing gene into the cerebrospinal fluid of children with GAN. The treatment approach uses a genetically modified virus to deliver the gigaxonin gene, which is expected to pave the way for treatments for other related diseases.
A new point-of-care EVD test has been shown to be faster and as sensitive as a conventional laboratory-based method, detecting the virus in just a small drop of blood. The rapid diagnostic test could help identify case contacts and ultimately curb Ebola's spread by quickly confirming or ruling out cases.
In a commentary published in The New England Journal of Medicine, two experts argue that lifting federal funding bans for needle exchange programs is crucial to protect the health of injection drug users. Needle exchanges can significantly reduce HIV transmission by providing clean needles and promoting opioid replacement therapies.
A Yale University study found that an arthritis medication restored skin color in a vitiligo patient after just two months of treatment. The patient experienced partial repigmentation on her face, arms, and hands, with nearly all white spots gone after five months.
Astronomers have discovered a colossal cloud of hydrogen dispersing from the warm, Neptune-sized planet Gliese 436b. The enormous gaseous tail is about 50 times the size of its parent star and may offer clues on how hot super-Earths form around other stars.
The Bulletin of Atomic Scientists has received a two-year grant to support a museum display about nuclear energy and workshops to improve public science communication. The grant will also help establish emerging experts in communicating complex scientific concepts to policy leaders and the general public.
A new study has definitively identified the head of a 500-million-year-old creature, revealing a ring of teeth and simple eyes. The discovery helps scientists reconstruct the common ancestor of ecdysozoans, a group including insects, spiders, and crustaceans.
Scientists have developed a rapid method to distinguish between left- and right-handed molecules in a mixture, offering potential breakthroughs in drug development and disease diagnosis. The Mass-Selected PhotoElectron Circular Dichroism technique can identify molecule handedness with high accuracy, even in complex mixtures.
AGU researchers explore the impact of the Sabah earthquake on sediment production and river systems in Malaysia, while also discussing improved predictions for Arctic sea ice extent. The findings highlight the urgent need to better understand and predict these natural phenomena.
New UCLA research reveals that vitamin B12 can lead to pimple-prone skin by changing the activity of facial bacteria. This finding may help identify new treatments for acne by targeting specific mechanisms in the skin. The study, published in Science Translational Medicine, sheds light on one key role that B12 plays in acne development.
The Mediterranean loggerhead and green turtle populations are threatened by human-induced threats, with a bycatch rate of up to 200,000 loggerheads per year. Researchers emphasize the importance of rescue centers and first-aid stations, calling for improved communication and collaboration among existing centers.
Scientists developed a computer model that studies ocean mixing in vast eddies, clarifying the complex processes driving ocean storms. The model enables researchers to study heat and carbon fluxes into the deep ocean, increasing global climate simulation accuracy.
Researchers used camera traps to monitor the behavior of dwarf porcupines in the Lower Urubamba Region of Peru, revealing that they are unable to leap across canopy gaps. The study also showed that these small mammals have a strong affinity for natural canopy bridges, which provided them with access to resources on both sides.
The European Society of Cardiology has published first-ever recommendations for managing cardiac arrhythmias in patients with chronic kidney disease. The guidelines emphasize the importance of considering renal impairment when choosing antiarrhythmic strategies, drugs, and anticoagulants.
Researchers at North Carolina State University have developed a new power scheduling technique that coordinates energy produced and stored by conventional and renewable sources. The approach replaces traditional centralized management with decentralized, distributed computing, enabling more efficient and secure energy distribution.
A new Stanford University School of Medicine study found that cystic fibrosis is more deadly for Hispanic than non-Hispanic patients, with almost three times the mortality rate. Despite equal access to CF specialty clinics, genetic differences may be contributing to this disparity.
The Vietnam Ministry of Health recognized Boston University School of Medicine for advancing hospital nutrition in Vietnam through education, clinical service, and research. A three-prong approach led by Carine Lenders and Elizabeth Henry improved outcomes and educated medical professionals about the importance of nutrition.
A digital map of the ageing brain could aid diagnosis by comparing patients' scans with a detailed map of the healthy ageing brain. The atlas was able to pinpoint changes in brain structure that can be an underlying sign of early Alzheimer's disease.
A study led by Duke University researchers found that parrots have distinct brain regions, called 'shells,' that are involved in vocal learning and may contribute to their ability to imitate human speech. The study also suggests that the shells may be responsible for the species' exceptional vocal mimicry abilities.
Researchers at UCF developed a technique for creating the world's first full-color, flexible thin-film reflective display inspired by nature. The new method reflects ambient light and can be controlled by voltage, offering potential implications for various electronics and whole new categories of displays.
Research suggests minority children are less likely to receive help for disabilities than similarly placed white children, due to greater risk factor exposure. This disparity affects the odds of identification as learning disabled, intellectual impaired, or having emotional disturbances.
Researchers use ALMA to observe dust contents of galaxies at redshift 5-6, revealing a new evolutionary stage. Average-sized galaxies contain less dust than expected, suggesting a previously unseen transition from gas to the first generation of galaxies.
A national survey found that patients are interested in using email and Facebook to manage their health, but few actually do so. Only 7% of respondents use their physicians' websites to access their own health information, highlighting a disconnect between patient interest and current institutional practices.
A unique consensus paper on patient preferences for arrhythmias management emphasizes the importance of education and shared decision-making. The document highlights patients' concerns, such as stroke prevention and bleeding risks, and recommends tailored information and incorporation of patient preferences into management decisions.
A new dinosaur, Sefapanosaurus, has been discovered in South Africa with distinctive features such as a cross-shaped ankle bone. The fossil, found in the late 1930s, provides insight into transitional early sauropodomorph dinosaurs roaming southern Africa.
Researchers found that norepinephrine enhances the ability of neurons to code for complex sounds by decreasing background noise firing. This mechanism is separate from estradiol's effects and provides new insights into neuromodulator interactions and auditory processing.
Scientists at the Institut Pasteur sequenced three distinct Ebola virus variants co-circulating in Guinea, with each variant defined by unique mutations affecting viral proteins. The study highlights the genetic diversity of the viruses circulating in Guinea during the epidemic's spread and will aid in optimizing treatments and vaccines.
Researchers have successfully created graphene biosensors that can selectively bind to specific molecules, allowing for precise detection and control. This breakthrough enables the development of inexpensive 'lab-on-a-chip' devices for medical diagnostics, promising a significant impact on healthcare.
Rapidly turning lovebirds execute extremely fast head turns when their wings cover their eyes, shortening blurry phases and maintaining stable vision. This super-fast behavior allows them to make split-second decisions during maneuvers.
Scientists have revealed the Antarctic region is rich in species, with diverse ecosystems and micro-organismal life. The study highlights the need for comprehensive protection of the Ross Sea and improved conservation efforts to preserve this unique biodiversity.
Researchers have identified a new species of Yeti Crab, Kiwa tyleri, found in the Antarctic region surrounding hydrothermal vent systems. This unique crab thrives in extreme environments with temperatures and densities that are challenging for other marine life.
A study found that compounds in New Zealand blackcurrants increased mental performance indicators such as accuracy and attention, while also reducing the activity of monoamine oxidase enzymes. This may lead to potential benefits for brain health and managing symptoms of disorders like Parkinson's disease and depression.
A team at Harvard's Wyss Institute discovered that bacteriostatic antibiotics slow down oxygen consumption, reducing cellular respiration and making bacteria tolerant. This can explain why certain antibiotic therapies fail. The findings provide a new strategy for developing urgently needed therapeutics.
The Louisiana State University Biomedical Research Network has received a $18.5 million grant from the National Institutes of Health to support biomedical research, faculty development, and infrastructure improvements. The program aims to increase the biomedical workforce in Louisiana and create a pipeline of future research scientists.
A new study from Arizona State University has revealed the causes of stress-corrosion cracking in metal alloys, leading to a deeper understanding of how to design crack-resistant materials. The research team's findings suggest that certain metals can fracture at high speeds, threatening the mechanical integrity of critical infrastructure.
A new US study reveals that end-stage kidney disease patients who receive specialized care have significantly improved survival rates and access to life-saving treatment. The research highlights the importance of timely referrals to nephrologists in reducing mortality risks, particularly in low-performing regions.
A multicenter, double-blind study found that sTMS therapy was significantly more effective than sham for treatment-naive and treatment-resistant patients with MDD, achieving a clinical response rate of 34.2%. The device also showed an attractive safety profile, with no significant adverse events.