A study on local salespeople's pricing discretion reveals that central, optimized pricing yields higher profits (20%) than local pricing (11%), improving overall profitability. The hybrid approach balances HQ analytic capabilities with field deal-specific information.
A recent study by Rockefeller University researchers has uncovered the connection between malaria and a deadly blood cancer called Burkitt's lymphoma, which predominantly affects children in equatorial Africa. The research found that the malaria parasite causes DNA damage in B lymphocytes, leading to cancer-promoting changes.
A representative survey of Mogadishu's population used remote sensing and smartphone technology to gather data on household dynamics, access to electricity, and child education. The findings revealed significant challenges in collecting accurate data due to security concerns and fragmented authority structures.
Hybrid hepatocytes, discovered by researchers at University of California - San Diego School of Medicine, have been found to proliferate and replenish liver mass after chronic liver injuries, showing promise as a therapeutic option for liver diseases. Unlike induced pluripotent stem cells, hybrid hepatocytes do not contribute to cancer.
The Ocean Health Initiative aims to protect and restore coastal and marine habitats, supporting the conservation of threatened marine and coastal species. The program, funded by a $1.5 million pledge from SeaWorld Entertainment, will focus on key estuaries along the Eastern Atlantic and Gulf of Mexico.
A study found that most donors and recipients support sharing health information, but not social details. The transplant team should be involved in the discussion, according to both parties.
Researchers at Oregon State University have made a significant advance in photodynamic therapy to combat ovarian cancer, achieving complete cancer cell elimination with no regrowth of tumors. The new approach combines existing techniques with compounds that make cancer cells vulnerable to reactive oxygen species, reducing natural defen...
Rings made of titanium are difficult to remove from swollen fingers due to their resistance to cutting methods. A new solution has been developed by plastic surgeons using bolt cutters, which work in under 30 seconds and can be performed solo without damaging the finger.
The UW optimization algorithm, RDIS, breaks down complex problems into smaller chunks, solving them exponentially faster. In protein design and self-driving car applications, RDIS performs significantly better than existing methods, accurately mapping images into realistic spaces.
A new Penn study analyzing insurance claims data suggests that repackaged Avastin injections do not carry a higher risk of endophthalmitis than commercially available Lucentis. This finding contradicts the FDA's planned restriction on Avastin's ophthalmic use and may inadvertently increase infection risk for patients.
Researchers have identified a protective mechanism used by beneficial bacteria to safeguard intestinal cells from stress and damage. By stimulating the Nrf2 pathway, these bacteria can help prevent weight loss and death after radiation exposure, as well as protect against toxic herbicides like paraquat.
Studies reveal age-related changes in anesthesia-induced brain activity, including reduced EEG oscillations and altered synchronization in older patients. In contrast, young children show distinct brain wave patterns that mirror development milestones.
Researchers developed an algorithm to analyze and critique digital photographs' composition, providing feedback on perceived aesthetics. The system relies on psychological theories of human vision and opinions of people, helping photographers improve their work.
A study from the Centre for Addiction and Mental Health found that individuals with a genetic subtype of schizophrenia who were born with low birth weight or prematurely had nearly one in two risk of developing schizophrenia. This is compared to those without schizophrenia, where the risk was lower.
The American Heart Association's scientific statement found that mobile health technologies can be effective for managing weight, increasing physical activity, and quitting smoking. However, more research is needed to fully understand their effectiveness for other health conditions.
Researchers analyzed case systems in over 600 languages, finding that complex constructions tax the brain more than simple ones. The brain activity is stronger for simple cases, leading to simplifications and changes in grammatical structures.
A two-week research expedition collects sea floor sediments and water samples at the site of Mexico's 1980 IXTOC blowout to project the impact of the Deepwater Horizon spill. The study aims to better predict long-term environmental effects of oil spills.
The NYU College of Nursing's 'Community/Clinical Primary Care of Older Adults Program' aims to integrate geriatrics with primary care and community resources. The program will provide education and support for older adults, families, and caregivers, promoting healthy aging and managing chronic diseases.
Researchers at Stanford University have genetically engineered yeast to produce hydrocodone and other opioid painkillers, enabling a faster and potentially less expensive way to produce plant-based medicines. The breakthrough could lower costs and increase access to pain medications for 5.5 billion people worldwide.
A study found playing Tetris for three minutes reduced cravings for drugs, food, and activities like sex and sleeping by approximately one fifth. The benefits were maintained over a seven-day period.
Researchers found that patients with methylmalonic acidemia received more leucine than recommended, leading to growth and brain development problems. Reducing medical food intake resolved amino acid deficiencies without increasing protein intake.
A Korean team tunes black phosphorus' band gap to form a superior conductor, enabling mass production for electronic and optoelectronic devices. This breakthrough allows for great flexibility in device design and optimization.
Researchers from Georgia Institute of Technology discovered 11 previously unknown Internet browser security flaws using a new cyber security analysis method. The team developed a proprietary detection tool called CAVER to catch vulnerabilities in C++ programs, resulting in significant contributions to the security of the Internet.
A study found that multigene panel testing identified harmful mutations in moderate-risk genes and Lynch syndrome genes among 3.8% of women negative for BRCA1 and BRCA2 mutations. The test also recommended additional disease-specific screening and prevention measures for mutation-positive cases.
Researchers successfully synthesized thebaine and hydrocodone in yeast, offering a novel microbial-based production process for opioids. The breakthrough could significantly reduce production time and potentially create a new source of pain relief worldwide.
A new study from Indiana University researchers emphasizes the critical role of spontaneous communication and improvisation in end-of-shift handoffs. The findings confirm previous studies in other industries and suggest that traditional checklists may not provide sufficient psycho-social information for effective handovers.
A team of astronomers has discovered a Jupiter-like exoplanet called 51 Eridani b, which shows the strongest methane signature ever detected on an alien planet. The new planet is the faintest exoplanet on record and provides clues about how planets formed around the sun.
Researchers analyzed 43 patients with hypoplastic left heart syndrome (HLHS) who underwent either an arterial or venous shunt as part of the hybrid palliation procedure. The study found that the arterial shunt group showed better pulmonary arterial growth, shorter surgical times, and higher oxygen saturations at discharge. However, no ...
David Williams, a leading expert on human vision, has received the Beckman-Argyros Award for his pioneering work on adaptive optics technologies. The award recognizes his transformative breakthroughs in vision research, enabling improved vision correction and treatment of eye diseases.
A UC Riverside-led team discovered that ants detect a unique blend of hydrocarbons on individual cuticles to recognize different castes and intruders. This sophisticated pheromone system allows ants to coordinate their behaviors efficiently in large colonies with multiple castes.
A study found that screening women with suspected hereditary breast or ovarian cancer risk for additional genes provides important information for changing clinical management. Most patients with identified mutations were recommended for enhanced screening or preventive measures, and close relatives should also be screened.
Research reveals that depressive symptoms, stress, anxiety, and anger are associated with increased atherosclerosis markers in RA patients. Screening and treatment of psychosocial symptoms may curb the cardiovascular disease burden in this patient group.
Astronomers using Gemini Observatory's new Planet Imager have probed a newly discovered world in unprecedented detail. The planet, 51 Eridani b, is about two times the mass of Jupiter and features a Solar System-like atmosphere with methane detection.
Researchers aim to develop multifunctional coatings that protect surfaces while adding value through sensing capabilities. The new ATOMIC center will focus on creating atom-thin materials for various industries, including energy and manufacturing.
Researchers have found that the mortality rate for extremely preterm infants has not improved significantly since 2000, despite advancements in medical technology and treatment. Data from over 47,000 records shows a decline in mortality rates from 1990 to 2000, but no significant improvement from 2000 to 2010.
New research found that individuals with high autistic traits generate fewer but more original and creative responses during divergent thinking tasks. The study suggests that these individuals may approach creativity problems in a unique way, utilizing less common strategies to produce unusual responses.
A new sensor developed at Duke University uses metamaterials and compressive sensing to separate overlapping sounds in loud environments. The device achieved a 96.7% accuracy rate in distinguishing between three identical sounds sent from different directions.
A recent study from McGill University Health Centre reveals that gestational diabetes in mothers can be a predictor for type 2 diabetes in their fathers. The research analyzed data from Quebec between 1990 and 2007, finding that men whose partners have gestational diabetes are 33% more likely to develop the disease.
A new method for personalizing bladder cancer treatments has been developed by researchers at the University of California - Davis Health. The approach uses tumor xenografts to identify effective therapies, which can be tested in mice before being administered to patients.
A study analyzing over 4,000 fossil bones from the Dikika site in Ethiopia confirms that marks on two 3.4 million-year-old animal bones were caused by butchery with stone tools, not trampling. The findings support a previous interpretation published in Nature in 2010 and provide new evidence for human evolution.
Tropical Storm Hilda is weakening due to diminishing winds, with maximum sustained winds holding at 45mph. The storm is expected to move west-southwest and produce heavy rainfall and life-threatening flash floods across the Hawaiian Islands.
A new study published in the Journal of the Pediatric Infectious Diseases Society finds that US chickenpox cases have declined by 93% since the introduction of the vaccine in 1995, thanks to increased vaccination coverage. This decline is attributed to herd immunity, which protects those who are not immunized themselves.
Conservationists at Lincoln Park Zoo successfully reproduced black-footed ferrets using frozen semen from a deceased ferret, significantly increasing the species' genetic diversity. The offspring will help recover the endangered population and increase its chances of survival.
A Mayo Clinic-led study has validated the National Cancer Institute's Patient Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE), a tool used to track side effects in cancer clinical trials. The study found that PRO-CTCAE was accurate, reliable and responsive compared to other measures.
A team of researchers has discovered a Jupiter-like planet, 51 Eridani b, within a young system that could provide new understanding of how planets formed around our sun. The planet shows the strongest methane signature ever detected on an alien planet, yielding clues about its formation.
A team of German scientists challenges the theory that a large mantle plume played a dominant role in the break-up of the super-continent Gondwana. Seismic measurements reveal that the impact of the mantle plume on the continental crust is surprisingly small.
Scientists confirm human activity, not climate change, as main driver of megafauna extinction over the last 80,000 years. The study's findings shed light on a long-standing debate and suggest that early humans were responsible for the demise of iconic species such as the woolly mammoth and sabretooth tiger.
Heavy smokers and obese individuals may experience significant weight gain after quitting smoking due to factors like daily cigarette consumption and body mass index. Researchers analyzed data from over 12,000 participants to find that those who quit smoking gained an average of 23 pounds among smokers of 25 or more cigarettes per day.
Researchers have developed an optical chip that can process photons in an infinite number of ways, a major step forward in creating a quantum computer. This breakthrough brings together existing quantum experiments and paves the way for new protocols, making it easier to conduct research and discover new science.
Researchers found that lager yeast, used in 94% of beer production, originated from the accidental hybridization of Saccharomyces cerevisiae and S. eubayanus yeasts around 500 years ago. The study reveals how these natural processes led to the development of a yeast that could thrive in cold temperatures.
Researchers developed vitamin A fortified sweet potato varieties to combat blindness in Africa and South-Eastern Asia. Impilo and Purple Sunset are the most promising varieties, offering high beta-carotene content and adaptability to different growing conditions.
Scientists use archived data from NASA's Hubble Space Telescope to study 13 unusual exploding stars, known as supernovae. These young stars were ejected from their galaxies at high speeds, and astronomers believe that supermassive black holes in merging galaxies played a key role in their ejection.
A team of Penn State researchers, led by Ping Li, has been awarded a nearly $1 million grant to investigate how readers comprehend science texts. The project aims to capture cognitive and brain representations during and after reading, with implications for STEM education.
A $7 million grant from the Bill & Melinda Gates Foundation supports research to eliminate river blindness and elephantiasis, two neglected tropical diseases affecting millions. Researchers will conduct field projects in eight countries and resuming a project suspended due to Ebola.
A team of scientists has quantified the carbon dioxide emitted by US rivers and streams, finding that in-stream respiration may be a larger source than previously thought. The study's findings are crucial for predicting how changes in land use and climate will impact global greenhouse gas emissions.
Researchers at University of California, San Diego School of Medicine reveal a more accurate structure of Protein Kinase C (PKC), providing new targets to fine-tune the enzyme's activity. The corrected structure suggests ways to turn PKC 'on' for cancer treatment and 'off' for neurodegenerative disease treatment.
A new study suggests that rogue supernovas that explode in deep space were likely kicked out of their galaxies at high speeds and then ejected into space by the gravitational pull of a binary black hole. The study, published in Monthly Notices of the Royal Astronomical Society, used data from NASA's Hubble Space Telescope to trace 13 h...
Researchers found that species with varying color drawing are generally more numerous and fluctuate less in number from year to year. This could help explain why some insect species cause substantial damage in agriculture and forestry, as their population fluctuations were not synchronised among different species.
A study by University College London found that warm, stagnant water from the deep Arctic Ocean and Nordic Seas contributed to the end of the last Ice Age. The researchers used proxy data to reconstruct past ocean circulation changes, which showed a warmer deep Arctic Mediterranean during glacial times.
Researchers found that ribosomes can translate the 'untranslated region' of mRNA, producing small proteins whose functions are unknown. This discovery opens up new questions about cancer cell growth and how cells respond to stress.