Researchers at LCSB have successfully grown dopaminergic neurons in a three-dimensional cell culture system. The system models the natural conditions of the brain and is significantly cheaper than existing methods, allowing for the automation of drug testing.
India's abortion law is criticized for its arbitrary 20-week cut-off, compelling women to continue pregnancies against their wishes. This can lead to physical and mental trauma, unsafe abortions, and related maternal mortality.
Researchers use light therapy glasses to trigger neurotransmitters and reset sleep cycles in lung cancer patients. Studies found that 50-80% of lung cancer patients experience severe insomnia, which can persist for eight years after diagnosis.
A new approach to diagnose pneumonia in critically ill patients has been identified through a breath analysis method. The study found that chemically analyzing breath specimens can reveal bacterial infection in ventilated patients at risk of developing pneumonia, providing a potential game-changer for clinical practice.
A study using NASA satellite data found that collecting rainwater for vegetable irrigation in India can reduce water bills by up to 4,522 rupees per year. This can provide a profit of between 1,548 and 3,261 rupees per year, boosting cost savings and increasing quality of life.
A new study by Brigham Young University researchers provides a rigorous estimate that about 10 percent of working households in the US are poor. Households led by women, minorities, or individuals with low education are more likely to be poor but still employed.
Scientists designed a new biochemical pathway in E. coli that can efficiently produce isobutyl acetate from both glucose and acetate, increasing its yield to 75 percent. This breakthrough could have significant applications in biotechnology, particularly in the production of flavoring agents, solvents, and fuels.
Kasturi Haldar and Grant McFadden emphasize the importance of basic research in their articles on PLOS Pathogens. They share their personal experiences and highlight how fundamental research can lead to breakthroughs in fields like malaria, cancer, and inflammatory diseases.
A NYU study found that a life review writing workshop combined with student interactions enhances the sense of purpose for older adults living independently. The program showed significant benefits in promoting well-being and reducing depressive symptoms among community-dwelling seniors.
Scientists used Sandia's Z machine to verify the metallic phase of hydrogen, solving a long-standing discrepancy in Saturn's age. The experiment found that dense hydrogen can become atomic, releasing energy that could explain Saturn's temperature.
A new study found that certain pollutants penetrate further into the feto-maternal system, causing harm to fetuses. The research analyzed pollutant levels in cord blood and maternal tissues, revealing heavy metals like mercury and lead easily pass through the placental barrier.
Scientists at the University of York and GlaxoSmithKline Australia have made a groundbreaking genetic discovery in poppies that could lead to more effective painkillers. The discovery of the STORR gene provides new insight into how poppy plants produce morphine, a key step towards developing bespoke poppy varieties.
A study found that participants who were exposed to prejudiced comments posted by others showed an increase in their own levels of prejudice toward Asians. They also tended to post more prejudiced comments about Asians themselves. The researchers suggest that anti-prejudiced comments can have a beneficial impact in reducing racial bias.
Recent changes to EU regulations have led to an increase in imported pets from Eastern Europe, where rabies is endemic, raising concerns about the effectiveness of current checks. The study found that many stray and rescue dogs had low antibody levels against rabies, suggesting potential risks for these animals.
The study identifies two enzymes, KDM4A and KDM4C, which alter gene expression in embryonic stem cells to direct their differentiation into endothelial cells. The enzymes work through epigenetic modifications, changing the activity of genes without altering DNA itself.
Researchers found that lymph node metastases do not require new blood vessels but instead use existing ones, providing a mechanism for resistance to angiogenic therapies. The study suggests alternative treatments may be needed for patients at risk of lymph node metastasis.
Researchers at The Wistar Institute identified specific mutations in H3N2 viruses that made the 2014-2015 flu vaccine less effective. Antigenic drift, a phenomenon where viruses accumulate mutations to evade immune response, was found to be a key factor.
University of Alberta scientists investigate physical principles underlying prion protein formation, with potential applications for diseases like Alzheimer's and Parkinson's. Their recent discovery sheds light on microscopic mechanisms governing protein misfolding, offering a new step towards developing therapeutics.
Researchers found that urine samples with higher acidity actually hindered bacterial growth due to the presence of specific compounds called aromatics. On the other hand, samples with less acidity showed increased activity of siderocalin, a protein that deprives bacteria of iron.
The Head Start program empowered poor children and civil rights activists in Mississippi by including them in the administration of the programs. The program also taught black history and civil rights, providing an alternative to electoral power.
Researchers have developed new approaches to estimate overall solvent content, model disordered bulk solvent, and identify distinct electron density of ordered solvent molecules in macromolecular crystals. Advanced models are needed to improve understanding of the protein-solvent interface region.
A study highlights a significant safety concern with linear gadolinium-based contrast agents (GBCAs), which can lead to brain gadolinium deposits in patients. The researchers found that repeated use of these agents causes persistent MRI abnormalities and high total gadolinium concentrations in the deep brain, highlighting the need for ...
The hospital has successfully integrated two common imaging techniques to produce a three-dimensional anatomic model of a patient's heart. The technology combines computed tomography (CT) and magnetic resonance imaging (MRI) with echocardiography, enabling more accurate diagnoses and treatment plans.
Research suggests that medically complex patients with newly diagnosed Type 2 diabetes who receive early endocrinologist care have lower risk of cardiovascular events. The study, which analyzed Ontario health data, found that these patients had a 10-20% lower risk of heart attack, stroke, and death from coronary heart disease.
Researchers developed targeted therapy using immunoglobulin-A antibodies to neutralize specific receptors in polycystic kidneys. The strategy enables repurposing of existing monoclonal antibodies for PKD therapy, opening up new class of therapeutics.
Rettsyndrome.org announces new Translational Research Awards to tackle nonsense mutations in MECP2 gene, aiming to develop treatments for Rett syndrome. The awards include the Read-Through Program and Neuro-Habilitation grants, furthering research towards new pharmacologic treatments and improved clinical practices.
A recent case study reveals that infection preventionists spend an average of five hours and eight minutes per day collecting and reporting hospital infection data, leaving little time for hands-on patient care. This finding highlights the need for adequate staffing and resources to ensure effective infection control practices.
A single mutation in the H3N2 virus helped it evade the immune system's defenses, making last year's flu vaccine less effective. Researchers have identified this mutation as a key factor in the mismatch between the vaccine strain and circulating strains.
Experts identified strategies for optimizing EHRs to better manage CKD patients, including standardizing data storage and accessibility. Well-designed EHRs can monitor patient conditions, facilitate collaboration among providers, and support patient self-management.
Scientists at the University of Pennsylvania have identified a stem-like progenitor cell, called cardiomyoblast, that produces only heart muscle cells. This discovery is expected to accelerate research into cardiac therapies and potentially lead to new treatments for heart damage.
The Transparency and Openness Promotion (TOP) Committee has outlined new guidelines to strengthen transparency and reproducibility practices in science research. The guidelines aim to increase openness and confidence in findings by promoting the sharing of data, code, and research materials. By adopting these standards, researchers can...
A study found that chimpanzees are sensitive to behaviors towards infants and react emotionally to violations of social norms within their own group. They show a 'bystander effect' when an infant from another group is harmed, but not otherwise.
Researchers have identified over 14,000 genes in the blowfly genome, which can now be investigated for potential drug and vaccine targets. The discovery provides insights into the fly's molecular biology and its interactions with sheep, offering new avenues for combating the devastating flystrike disease.
Researchers at Boston Children's Hospital develop a new treatment strategy targeting nerve endings to combat allergic asthma. By selectively silencing sensory neurons called nociceptors, the approach reduces inflammation and bronchial twitchiness in mouse models of acute and chronic asthma.
Researchers found that songbirds rely on patterns in much the same way as people do when learning to recognize and categorize speech sounds. By training starlings to differentiate between complex auditory patterns, the study showed that birds can learn to categorize motifs into meaningful categories.
Scientists discover corals are already adapting to global warming through genetic variants that allow them to tolerate warmer waters. By exchanging coral immigrants, humans can help spread these heat-tolerant genes and boost reef survival.
NASA has developed a new technology to protect the James Webb Space Telescope from contamination, using Molecular Adsorber Coating (MAC) panels. The MAC panels capture outgassed molecular contaminants in the vacuum chamber, preventing them from affecting sensitive instrument components.
Scientists at Salk Institute and Sanford Burnham Prebys Medical Discovery Institute have developed a drug that inhibits the first step of autophagy, a process used by cancer cells to recycle nutrients. This breakthrough opens new avenues for treating resistant cancers.
A new study found that errors on memory and thinking tests may signal Alzheimer's disease up to 13-18 years before the disease can be diagnosed. Those who scored lower overall had an increased risk of developing the disease, with higher scores associated with a lower risk.
The UK Parkinson's Excellence Network is a multi-disciplinary effort bringing together patients, healthcare professionals, and social care experts to develop patient-centered care. The network aims to improve treatment and raise awareness of the need for better care, with a focus on education and service development.
Indiana University researchers found that restoring missing microRNA-29 in pancreatic cancer stromal cells reduced the viability and growth of cancerous cells. The study suggests that miR-29 could be a potent therapeutic agent against pancreatic cancer by targeting reactive tumor stroma.
A recent Cornell Food & Brand Lab study found that serving vegetables at dinner increases the perception of being a better cook and a more loving parent. Serving veggies even if not liked can make the meal tastier, according to lead author Brian Wansink.
Despite fewer legal barriers, women in developed countries still face significant inequities in abortion access due to inadequate service provision, moral opposition, and inadequate training. The review suggests improving access by increasing training, boosting service options, and making services more affordable or free.
Researchers found that up to 20% of a mosquito population's genome is subject to evolutionary pressures, leading to local adaptation and potential resistance to pesticides. The study provides insights into the contemporary evolution of mosquitoes and informs strategies to control populations.
A small pilot study found an experimental treatment approach can send deadly leukemia into remission in patients who have failed standard therapy. The combination of immunotherapy and gene manipulation buys critical time for patients to receive a potentially life-saving stem cell transplant.
A study by University of Basel researchers found that fructose stimulates the reward system in the brain to a lesser degree than glucose, leading to increased satiety hormone levels and reduced feelings of fullness. This may contribute to the development of various disorders such as obesity, diabetes, and fatty liver disease.
A University of Kentucky researcher is developing an artificial blood technology for mosquitoes, which can help sustain colonies in resource-limited areas and combat diseases like malaria. The approach involves sterilizing mosquitoes using a bacterium and has already shown promising results in controlling Asian tiger mosquito populations.
Researchers monitored Helheim Glacier for 55 days and detected 10 large-scale calving events, revealing unique quakes registering magnitude five on the Richter Scale. These glacial earthquakes can serve as proxies for glacier edge breaking, offering insights into ice loss from glaciers.
Researchers from top institutions emphasize the need for high-quality science by addressing issues such as replication problems, researcher misconduct, and sensationalism. They propose solutions like rewarding quality work, mentoring peer-reviewers, and voluntary withdrawal of flawed papers.
A University of Toronto study found that augmented-reality displays on windshields can reduce driving accuracy and increase the risk of accidents. Drivers must divide their attention between road conditions and digital warnings, leading to slower reaction times and missed warnings.
A new pilot study found that Montmorency tart cherry juice reduced upper respiratory tract symptoms in marathon runners. The study also showed lower markers for inflammation compared to a placebo group. This research provides encouraging evidence of the potential role of tart cherries in reducing exercise-induced respiratory problems.
A new INFORMS journal study provides more predictable ways to manage arrival traffic at airports with adverse weather. The research reveals that knowing early about late flights reduces the cost of Ground Delay Programs (GDPs) for flight operators, with a 13% reduction in delays observed.
A new study reveals that heat-tolerant corals can pass on their tolerance genes to their offspring, potentially helping reefs adapt to global warming. The research found that coral larvae from hotter regions were more likely to survive in warmer conditions than those from cooler regions.
Researchers found that early-age exercise in mice had positive effects on adult levels of voluntary exercise, including a reduction in body mass. The study suggests that early-life exercise may increase the likelihood of adults engaging in regular physical activity.
A new study by the U.S. Geological Survey and Florida Atlantic University reveals that past water conditions and availability are crucial factors affecting wading bird populations in the Everglades. The research found a 'lag effect' where wet conditions can take several years to impact bird numbers.
Researchers at UC Davis and the University of Delaware discovered that chloroplast tubes play a key role in plants' immune defense. The discovery reveals how chloroplasts deliver signals to the nucleus, inducing programmed cell death and preparing other cells to resist infection.
A five-session intervention teaches social and emotional competencies to reduce sibling conflict. Moms report improved emotion regulation after watching sessions and coaching their kids. Fathers also show reduced negative emotions when children's conflicts decrease.
A pilot program at a pediatric long-term care facility achieved significant reductions in antibiotic use, with a 59% decrease in topical antibiotics and an 83% decrease in orders without proper documentation. The program improved antibiotic prescribing practices through increased staff support and electronic medical record system changes.
Researchers discovered a way to suppress nonlinear distortions in optical fibers, eliminating signal regeneration needs. This breakthrough enables more bandwidth availability and increased data transmission.
Researchers found that the KaiC protein encodes the Earth's 24-hour rotation period at an atomic level. The protein's structure and reactivity regulate molecular rhythms, which could lead to new therapies for circadian rhythm disorders.