Researchers have pinpointed cell types responsible for common brain diseases, including Alzheimer's and Multiple Sclerosis. The findings suggest that developing medicines targeting microglial cells could offer hope for treating these conditions.
A recent study suggests that using paracetamol during pregnancy may reduce female fertility in subsequent generations. Researchers tested the effects of paracetamol and another painkiller on rats and found that female offspring had fewer eggs, smaller ovaries, and reduced reproductive function compared to those not exposed to the drugs.
James F. Kasting receives the award for his work on planetary atmospheres and habitability, providing insights into the origin of life on early Earth and the search for life on other planets
Researchers have successfully corrected a blindness-causing gene mutation in stem cells derived from a patient's skin cells, offering hope for personalized, precision medicine. The technology uses CRISPR/Cas9 gene editing to repair the damaged gene, and the corrected tissue can be transplanted without harm.
The Journal of Neuropathology & Experimental Neurology will now be published by Oxford University Press USA, publishing original articles on neuropathology and experimental neuroscience since 1942. The journal is the official publication of the American Association of Neuropathologists, Inc.
Researchers sequenced a seagrass genome, revealing genes that enable plants to adapt to saline environments. The study provides insights into salt tolerance and could inform crop breeding to improve resilience in the face of climate change.
Researchers have discovered a new class of catalysts that use iron-nitrogen compounds in graphene, achieving levels of activity comparable to platinum-based catalysts. The purification process allows for the creation of exclusively FeN4 centres, which provide high catalytic efficiency even without promoters.
A new study found that nearly two-thirds of women aged 70 and older with stage I breast cancer who are eligible to safely omit subsequent radiation therapy do not receive it. Despite guidelines recommending against radiation therapy for this group, the study suggests a lack of compliance or poor awareness among healthcare providers.
A new study funded by NIH suggests that ongoing HIV replication in lymphoid tissues maintains stores of the virus, a prerequisite for achieving a cure. Current ART regimens cannot eliminate persistent viral reservoirs, but sequencing data shows continued evolution over time without accumulating drug-resistant mutations.
Researchers at University of Bath found that life transitions like moving house can provide a window of opportunity to instill better environmental behaviors, such as recycling and energy use. The study suggests that targeted interventions during these times are more effective than blanket campaigns.
A new study finds that moderately farsighted preschoolers and kindergarten students perform worse in early literacy than children with normal vision. The researchers hope this research is an important step in clearing up the uncertainty surrounding what to do with these kids.
Researchers at UTA are designing safer cryotherapy devices to reduce nerve and tissue damage caused by extreme cold therapy. They will also investigate the physiological mechanisms behind blood flow reductions and develop new devices for precise treatment.
Researchers show that intense male competition can lead to speciation, erasing boundaries between species and creating new ones. This process is independent of natural selection and has significant implications for understanding biodiversity.
A recent study published in JAMA Surgery found that the use of biological mesh materials for abdominal wall hernia repair does not demonstrate added clinical benefits over synthetic mesh. The authors reviewed 20 studies and concluded that the expense associated with these devices cannot be justified without clear evidence of superiority.
Researchers found a 25-point IQ drop in carriers of the 16p11.2 gene deletion, even in individuals with normal IQ scores. The study quantified the additive effects of genetic mutations on cognition and behavior.
The study found that different subspecies of western rattlesnakes have distinct head shapes, which have evolved to accommodate feeding and reproductive behaviors. Combining head shape with genetic analysis confirmed that some groups should be classified as separate species.
A study published in the British Journal of Sports Medicine found that nearly a quarter of Division I college athletes reported depressive symptoms. Women were almost twice as likely to experience symptoms than their male peers. The researchers also discovered significant differences in depression rates across different sports, with fe...
Scientists have developed a flexible nanogenerator made from cellulose that can harness energy from the body, including heartbeats and blood flow. The device has been shown to charge capacitors and power small electronics.
New research reveals Palmer amaranth can cause significant soybean yield loss in Illinois, up to 30% in short periods, highlighting the need for early detection and management strategies.
A team of Penn State researchers is monitoring Nicaragua's Momotombo volcano with a $40,000 NSF grant. They're using GPS, seismometers and other equipment to track ground deformation, seismic activity and lava composition to predict potential eruptions and hazards.
Researchers found that queen bees emit a chemical pheromone that alters the DNA of their daughters, keeping them as sterile and industrious workers. This process involves DNA methylation, which suppresses queenly characteristics in workers.
Researchers found that high-protein diets combined with intense exercise can lead to significant muscle gain while losing body fat. The study involved 40 young men who followed a low-calorie diet with varying levels of protein, resulting in impressive muscle gains and weight loss.
The James Webb Space Telescope's 18 primary flight mirror segments are being installed using a high-precision robotic arm, requiring fraction-of-a-millimeter accuracy. The team uses lasers to measure distance and a coordinate system to place each segment, achieving precision better than the thickness of a piece of paper.
Two Georgetown University professors urge the World Health Organization to convene an Emergency Committee to advise on the emerging Zika pandemic and galvanize global action. They highlight the need for decisive action, mosquito control, health information campaigns, country-issued travel advisories, accelerated research, and vaccine d...
The American College of Prosthodontists has published clinical practice guidelines for patients and professionals to care for tooth-borne and implant-borne restorations. The guidelines emphasize the importance of lifelong professional and at-home maintenance to keep teeth healthy.
A study found that genes associated with diseases like Alzheimer's, schizophrenia, and autism also impact cognitive functions. Researchers analyzed data from 100,000 people in the UK Biobank to discover shared genetic influences between health and thinking skills.
Researchers discovered a rare genetic mutation in Turkish children with ataxia, which caused a significant impact on the brain's autophagy process. This finding has important implications for understanding and treating neurological disorders, such as ataxia and developmental delays.
Researchers show that large groups of people sharing in a conspiracy will very quickly give themselves away, using equation to estimate time before exposure. For instance, moon landing hoax would be revealed in just 3 years and 8 months.
A new study identifies four major factors leading to disputes over wind farms in Ontario, including socially mediated health concerns, financial benefits distribution, lack of meaningful engagement, and landscape impact. The research offers recommendations for addressing these issues to promote community acceptance of wind energy devel...
A European alliance, EHVA, has been granted 28 million Euros to develop novel preventive and therapeutic vaccines against HIV. The project aims to accelerate the development of innovative HIV vaccine concepts, focusing on prophylactic and therapeutic approaches.
Researchers successfully reconstructed the internal structure of a compound eye from a predatory crustacean dating back 160 million years. This groundbreaking discovery reveals that soft tissue was preserved and provides new insights into the evolution of visual systems, challenging previous assumptions about fossil preservation.
University of Washington scientists developed a mathematical model to explain the Madden-Julian Oscillation, a massive cluster of thunderstorms that affects global weather. The model predicts storm movement and formation, helping improve tropical rainstorm forecasts and medium-range global forecasts.
The Molecular Spectroscopy Group has created new multifunctional materials that mimic the photosynthetic organisms of plants. These materials capture a broad spectral range of light and convert it into chemical energy. They have been applied in various photonic applications, including tunable lasers and light modulators.
Researchers demonstrate Meselson effect for first time in any organism at genome-wide level, studying a parasite called T.b. gambiense. The study reveals that the parasite's inability to recombine with each other prevents genes from being exchanged between strains.
A recent review of 13 studies on weight-loss surgery found that being married might actually work against patients' chances of losing weight and keeping it off. The Ohio State University researchers discovered evidence that the impact of surgery extends to romantic relationships and family, potentially worsening marital dynamics.
A new species of the genus Amphilagus has been discovered in southeastern Siberia, revealing a biogeographic link between Asia and Europe during the Middle Miocene. The discovery confirms the widespread distribution of this group and sheds light on paleogeographic and environmental conditions that favored its expansion.
A recent study published in the American Journal of Cardiology found that early diagnosis and treatment of sleep apnea may reduce six-month readmissions for patients hospitalized with heart failure. Researchers discovered a significant reduction in hospital visits among patients who used positive airway pressure therapy regularly.
A recent study published by the University of Pittsburgh found a significant link between social media use and sleep disturbances in young adults. Participants who checked their accounts frequently or spent more time on social media had three times and twice the likelihood of sleep difficulties, respectively.
Research shows that Latino kids are more likely to be obese by ages 2-5 due to maternal obesity, less exclusive breastfeeding, and workplace issues. Breastfeeding can reduce obesity by 47 percent among Latino kids, but many Latina moms face barriers to initiating and maintaining breastfeeding.
Two randomized trials examine the effect of vitamin D supplementation during pregnancy on asthma and persistent wheezing in offspring. While no significant protective effect was found, a clinically important effect could not be excluded, suggesting further studies are needed.
Researchers have identified over 13,000 Zika cases in Colombia, with the country now second only to Brazil in reported infections. The team is exploring ways to control the spread of the virus using a bacterium that infects mosquitoes, aiming to prevent transmission and mitigate serious consequences like microcephaly.
A new study has demonstrated a molecular method that reduces the wait time to confirm transgenic work from weeks to just a few days. Digital drop PCR (ddPCR) was found to be reliable, fast and high throughput, making it a promising alternative to traditional methods.
A new study comparing smoking cessation therapies found that 12-week treatment with a nicotine patch, varenicline, or combination therapy produced similar quit rates at 26 and 52 weeks. The treatments did not differ significantly on any abstinence outcome measure.
Researchers found that bed bugs that fed after being treated with insecticides had significantly lower mortality rates than those that didn't. The study suggests that feeding stimulates detoxification enzymes, leading to increased resistance and survival.
Scientists Kaspar Sakmann and Mark Kasevich developed a new method to calculate effects in ultra-cold atom clouds, which can only be explained by quantum correlations between many atoms. This breakthrough enables accurate descriptions of complex many-body systems, such as Bose-Einstein condensates and collisions between these states.
A new report by a Boston University School of Public Health researcher links Gulf War toxins to illness in veterans, citing pesticide and nerve gas exposure as causally associated with Gulf War Illness. The study found structural and electrical abnormalities in the central nervous systems of deployed troops with GWI.
Researchers found that dieters ate 39% more cookies after seeing a negative message about sugary snacks compared to those who saw a positive message. Dieters who saw a two-sided message chose 47% fewer unhealthy snacks than those who saw a negative message.
Scientists have identified a protein called Tet3FL that acts as a 'guardian' against neurodegenerative diseases like Parkinson's. Tet3FL removes molecules called methyl groups from specific genes, keeping them active and maintaining cellular 'trash removal' processes.
Research supports the effectiveness of providing psychosocial interventions in combination with medications to treat opioid addiction. However, limitations were found in the amount and quality of evidence on safest and most effective combinations of medications and treatments.
A new study by Boston University School of Public Health researchers found a substantial association between state-level firearm ownership rates and killings of women by guns. State gun ownership rates explain 40 percent of the variation in women's homicide victimization rates, compared to just 1.5 percent for men.
Researchers found that ancient medicinal clay exhibits potent antibacterial activity against ESKAPE strains of bacteria, including Enterococcus faecium and Staphylococcus aureus. The rare mineral clay may provide a new treatment option for serious infections caused by these resistant pathogens.
A new study published in Environmental Health found a 19% increased risk of preterm birth among women exposed to high levels of small particle air pollution. The study also identified higher risks among mothers over 40, black mothers, and those with lower education levels.
New research reveals that Native American populations in the Southwest US collapsed rapidly in the 17th century due to sustained daily interaction with European colonizers, resulting in epidemic diseases, violence, and famine. The population decline had indirect effects on forest fires and climate, with findings published in PNAS.
Researchers have identified PTEN as a key player in Alzheimer's disease, where it drives excessive synaptic plasticity and impairs memory formation. A new study offers a promising approach to prevent this process, using a molecular tool that shields synapses from PTEN recruitment.
A new study reveals that grey squirrels may not be as hardy as thought and were helped more by humans in their conquest of the British Isles. The research shows that different populations are genetically distinct, tracing human intervention in their movement to new areas.
Research finds that personal pension funds beat their benchmarks on average due to the selection of easy-to-outperform benchmarks rather than investment skill. Focusing on a broader asset class can lead to better returns. The study also highlights the importance of considering diversification in pension saving allocation.
Death rates from leukemia in Europe are expected to decline, with the greatest falls seen among children and young adults. Improvements in treatment and management have contributed to this trend, but some leukaemias remain challenging to treat.
A new report estimates 4.3 million new cancer cases and 2.8 million deaths in China in 2015, with lung cancer the leading cause of cancer death. The study highlights the need to reduce risk factors and improve clinical care delivery to prevent avoidable cancer deaths.
A large study of over 20,600 breast cancer survivors found that those who quit smoking after diagnosis had a significantly lower risk of death from breast cancer. Quitting smoking led to a 33% reduction in mortality rate, with the highest risks observed among long-term smokers and former smokers.
Researchers have developed a high-performance network infrastructure that is open and programmable, using light to carry internet traffic. This technology has the potential to revolutionize optical network infrastructure, making it accessible to traditional programmers and application developers.