Researchers identified two drug combinations that could improve survival rates for breast cancer patients, including anti-inflammatory and lipid modifiers. The study analyzed data from nearly 10,000 women with breast cancer and found three pairs of drug interactions associated with better outcomes.
Research reveals that macaques possess the physical attributes necessary to produce intelligible human speech, yet their brains lack the neural circuitry required for this ability. This finding debunks the idea that vocal anatomy alone limits speech in nonhumans, highlighting the importance of brain evolution in human language.
A Cardiff University study found that home-based rehabilitation significantly improves visual function and daily life for people with low vision. Home visits by visual rehabilitation officers led to a greater improvement in visual function compared to standard hospital appointments.
Scientists have discovered a new mutation in the PKD1L1 gene associated with laterality defects and complex congenital heart disease. The study provides hope for affected families by offering prenatal or pre-implantation genetic diagnosis to prevent the condition from being passed on.
A new study reveals that many breast cancer survivors experience unmet needs for symptom management, leading to increased levels of anxiety and depression. Researchers are calling on healthcare providers to incorporate symptom management into routine follow-up care.
Michigan State University researchers have developed a low-cost nanogenerator that can harness energy from human motion, powering devices such as smartphones and headsets without batteries. The device, called FENG, is flexible, biocompatible, and scalable, with advantages including being lightweight and robust.
Recent evidence suggests a link between the gut microbiome and colorectal cancer development, with specific types of intestinal bacteria contributing to disease progression. Dietary-based therapeutic interventions, such as probiotics and prebiotics, may help modify the gut microbiome to reduce CRC risk.
Researchers at Massachusetts General Hospital have developed a significant improvement in brain implant technology, allowing for selective activation of targeted neurons. Microcoil implants generate magnetic fields that extend in specific directions, reducing the risk of activation of passing nerve fibers.
Scientists have found that Jupiter's massive gravity may have formed rare, high-velocity meteorites called CB chondrites. These meteorites suggest Jupiter was near its current size and in the asteroid belt when they were formed, about 5 million years after the solar system solidified.
Researchers study organizing principles behind high Z' crystal structures to understand material properties like solubility and bioavailability. By analyzing complex structures, they identify organization principles tied to chemical molecule details.
Researchers from Berkeley Lab will present various talks on climate modeling challenges, permafrost, induced seismicity and drought sensitivity in mountainous watersheds. They aim to map regions sensitive to drought conditions using historical data and identify environmental controls.
A UNIST research team led by Professor Joonbum Bae received a commendation from the Minister of Public Safety and Security for their groundbreaking collaborative rescue robots. The award recognizes their work on humanoid avatar robots with a teleoperating system that can be deployed in disaster response.
Global breast cancer mortality rates declined between 1987-2013, with 39 countries showing a decrease, including the US and most developed European nations. However, South Korea experienced an 83% increase, while Latin America saw scattered increases in mortality, except for Argentina and Chile.
A new study found that smoking intensity and duration are crucial factors in coronary heart disease (CHD) risk. Researchers discovered that smokers with longer exposure to cigarettes face a higher relative risk of heart disease compared to those who smoke the same number of cigarettes over a shorter period.
The EPA awards $1.1 million in grants to Virginia's VIMS and DEQ to protect and restore its wetlands, advancing the state's goal of preventing net loss and increasing ecological function. The funding will support efforts to identify vulnerable wetlands, develop management plans, and inform decision-making for development and preservation.
A team of researchers used neutron scattering to study the origins of unusual magnetic behavior in a rare earth metal oxide, revealing three key features: antiferromagnetic interactions, spin space anisotropy, and chemical disorder. These findings provide a better understanding of how quantum spin liquids exhibit exotic behaviors.
A study of 129,535 Americans aged 50+ found that never-smoking older African American women had the highest COPD prevalence, with 7% and 5.2% in White women, respectively. Hormones and second-hand smoke exposure may contribute to this vulnerability.
A deadly avalanche in 2016 killed nine nomadic yak herders in western Tibet, with climate change cited as a likely cause. Researchers found that meltwater lubricated the ice, allowing it to flow quickly down the mountain.
A recent study by University of Illinois researcher Dorothy L. Espelage found that nearly half of middle school students reported experiencing verbal sexual harassment, with 43% saying they were targeted in the past year. The study also revealed that students who dismissed their experiences with sexual harassment were more likely to pe...
A pilot study at MD Anderson Cancer Center found that image-guided biopsies accurately predicted residual disease in breast cancer patients after chemotherapy and/or targeted therapy. The study suggests that certain patients may be able to avoid surgery, paving the way for personalized treatment.
Scientists at NIFS successfully measure flow reversal of negative ions, revealing U-turn trajectory and beam extraction point. The study's findings improve performance of negative ion sources, essential for future fusion devices.
A Michigan State University research team discovered that Campylobacter jejuni in undercooked chicken triggers Guillain-Barre Syndrome, an autoimmune disease causing paralysis. The study offers new information for a cure and suggests that treatment with some antibiotics could worsen the disease.
The VENEX project offers an alternative solution to road humps by reducing vehicle speed through energy extraction, ensuring safety and minimizing impact on drivers. The award-winning innovation aims to reduce traffic-related victims and costs, promoting a safer transportation system globally.
A $3 million NIH grant will help UTHealth researcher Nitin Tandon decode how the brain processes written words into language. The study, using intracranial electroencephalogram (icEEG), aims to understand the mechanisms of reading and its connection to the broader language system.
Researchers found that Atlantic killifish populations can adapt to lethal levels of pollution due to the aryl hydrocarbon receptor signaling pathway. The study suggests that desensitization of this pathway is a key factor in adaptation, but also highlights potential risks and compensatory adaptations.
Scientists at the University of Bonn have successfully observed an important cell protein in action using a novel method that measures structural changes within complex molecules. This breakthrough allows researchers to elucidate cellular processes in their natural environment.
Women taking tamoxifen for breast cancer prevention experienced nausea and vomiting, which led them to discontinue the medication. A new analysis suggests that these symptoms were sometimes mistaken for tamoxifen side effects, highlighting the importance of accurate information on preventive therapies.
Siobhan Roberts will receive the 2017 JPBM Communications Award for her outstanding work in communicating mathematics to non-mathematicians through her writing. Her award-winning books include 'King of Infinite Space' and 'Genius at Play', which showcase her ability to make complex mathematical concepts accessible to a wide audience.
Researchers from Utah State University received the American Water Resources Association Award for their study on global megacity water challenges. The team characterized and compared the water issues faced by 28 United Nations-designated megacities, highlighting unique challenges in each city.
A recent study published in Nature Reviews Cancer suggests that progesterone could be a game-changer in treating recurring breast cancers. The hormone, when used in combination with current treatments, may reprogram estrogen action in the breast to improve cancer outcomes. Two new clinical trials are underway to test this approach.
The synthesized compounds showed potent anticonvulsant activity in the MES test, with Schiff bases of benzothiazol-2-ylamine being more effective than thiazolo[5,4-b] pyridin-2-ylamine. The log P values revealed a positive correlation with activity, with the most potent compound being benzothiazol-2-yl-(1H-indol-2-ylmethylene)-amine.
A study of over 16,000 patients found air pollution reduces pulmonary vascular function and increases risk of decompensated heart failure. Limiting physical activity in heavily polluted areas is recommended.
A study led by UC Riverside's Maurizio Pellecchia advocates for focusing on Bfl-1 as a drug target to fight cancer. The research team found that Bfl-1 is more relevant than previously thought and can be targeted with innovative inhibitors.
A computer model revealed monkeys could easily produce many different sounds, implying a basic form of spoken language could have evolved without changes in vocal anatomy. Monkeys' ability to vocalize was found to be unrelated to their speech capabilities.
The University of Houston has received a $66 million in-kind software grant from Siemens PLM Software to support its Industrial Design program. This grant provides students with access to advanced technology used by global companies, enhancing their training and employability.
A new study by SWOG found that duloxetine can significantly reduce joint pain in postmenopausal women with early stage breast cancer. The randomized trial tested the effectiveness of duloxetine against aromatase inhibitors, a common treatment for breast cancer, and showed rapid relief from pain.
Researchers found that peer-referral strategies outperformed traditional methods in detecting undiagnosed HIV among high-risk heterosexuals. The study suggests a new approach for identifying and treating undiagnosed HIV cases in the US, with potential to reduce transmission rates.
Researchers presented insights from the Curiosity rover's study of Mount Sharp on Mars, which helps reconstruct the geological history of the area. Additionally, they developed a method to distinguish between natural and manmade earthquakes using seismic wave characteristics. Furthermore, scientists observed gamma-ray bursts triggered ...
A study published by University of Texas MD Anderson Cancer Center found that older women with breast cancer who underwent less radiation therapy reported improved cosmetic satisfaction. However, reduced radiation was also associated with a slightly increased risk of disease recurrence. The researchers suggest that there may be an opti...
A new Penn study sheds light on racial disparities in cancer-causing genetic mutations, finding differences in mutation patterns between African American and Caucasian women. The research suggests biological differences and potentially different genetic factors may be at play, guiding targeted care for at-risk patients.
Tropical Cyclone Vardah showed strongest storms expanding west of its center, influenced by moderate vertical wind shear. The storm is expected to intensify and make landfall as a tropical storm south of Visakhapatnam, India, by December 12.
Researchers have found a new pathway in the liver that opens the door to treat non-alcoholic fatty liver disease. The pathway involves activating a protein called TRPV4, which releases nitric oxide and blocks an enzyme contributing to the disease.
Scientists identified a gene NAMPT that fuels glioblastoma growth and resistance to radiation therapy. Inhibiting NAMPT may improve treatment outcomes for most aggressive forms of the disease.
Researchers have discovered that capuchin monkeys in Brazil produce sharp-edged conchoidal flakes with smooth rounded facets, resembling the shape of scallop shells. These unintentionally produced flakes exhibit identical characteristics and morphology to intentionally produced hominin tools, dating back to 2.6 million years ago.
A new study at SABCS finds EndoPredict, a second-generation test, superior to Oncotype Dx in predicting breast cancer recurrence. The test accurately identified patients with low risk of recurrence, allowing them to forgo chemotherapy.
The study found that human ALOX15 has a higher capacity for producing anti-inflammatory lipid mediators than its lower primate counterparts. This suggests an evolution to better control inflammation and speed up the healing process.
Feldspar's unique surface defects enable ice crystals to grow, a discovery that sheds light on precipitation formation in clouds. The research found that microscopic edges and cracks on feldspar crystallites serve as active sites for ice nucleation.
A new study from UT Dallas finds that bestowing considerable power in the CEO does not create value for the firm during industrywide downturns. Concentrated power among CEOs leads to worse decision-making and a decrease in firm value, especially in competitive industries and high-discretion industries.
Online health communities help bridge disparities between rural and urban healthcare, providing a platform for patients to ask questions and share knowledge. The communities offer emotional support, amplifying the health capabilities of rural users and creating a supportive social network that transcends geographic constraints.
A new study reveals that diabetes drugs' weight loss effects are controlled by multiple brain regions, excluding the hypothalamus. Researchers hope to develop more effective treatments for obesity by understanding how these drugs work in the brain.
A new study found that only 20% of cannabis dispensary staff have medical or scientific training, despite recommending treatments to patients. The lack of training is concerning, as some recommendations may be ineffective and worsen patient conditions.
Researchers at Scripps Research Institute discovered that a human enzyme has evolved to change its shape and function without major architectural changes. This unique ability allows the enzyme to carry out new roles in humans, shedding light on diseases linked to mutations in aminoacyl tRNA synthetases.
Researchers have identified flavonoids in Gymnema sylvestre R.Br. plant parts and callus culture, which exhibit antidiabetic properties. The study aimed to develop a sustainable method for metabolite production using tissue culture, helping conserve the endangered species.
Research reveals that 20-40% of multiple myeloma patients have a defective ribosome, leading to a poorer prognosis but better response to Bortezomib treatment. The discovery has the potential to improve therapy selection for these patients.
A new study by researchers from the U.S. and France finds that multiple anomalies in gene expression, including failure to implant and placenta development, contribute to the high rate of pregnancy failure for cloned embryos. The study reveals critical developmental genes and hormonal signaling issues that lead to these failures.
Researchers at NIH's National Institute of Allergy and Infectious Diseases have established a new mouse model to study Salmonella meningitis. The model mimics the progression of the disease from the gastrointestinal tract to the brain, providing a new tool for investigating this potentially life-threatening illness.
Researchers found sedimentary rocks along the Colorado River valley exhibit regular tidal influences, pointing to 330 meters of seafloor uplift over the past 5 million years. The study resolves a 20-year-old debate on depositional environments and tectonic significance in the region.
Scientists have developed a biomimetic photosynthesis approach using graphitic carbon nitride material to store and release light-generated electrons for catalytic hydrogen production. This technology enables the production of storable solar fuels independent of solar irradiation intermittency.
A study from Center for Music in the Brain found that oxytocin enhances synchrony in finger-tapping pairs, indicating improved social bonding and prediction skills. The hormone's role in facilitating predictability explains its social effect without subjective affiliation.