Researchers develop biomimetic drive elements inspired by pine cones, which can open and close without energy consumption. The goal is to optimize building energy efficiency and reduce greenhouse gas emissions.
The HPTN 084 study enrolls 3,200 HIV-uninfected women in seven countries to test the safety and efficacy of a long-acting injectable cabotegravir compared to daily oral TDF/FTC. The study aims to increase HIV prevention choices for women, particularly in sub-Saharan Africa where they bear a disproportionate burden.
Researchers investigate pretreatment with etanercept to manage post-treatment inflammation in neurocysticercosis, a major cause of epilepsy worldwide. Etanercept suppresses inflammatory pathways involved in treatment-induced inflammation.
A VCU-led study found that individuals who exhibit sadistic tendencies are more likely to seek revenge against those who have wronged them. The research identified a multidimensional link between physical aggression, impulsivity, and aggressive pleasure in relation to revenge-seeking behavior.
A collection of over 200 fossilized pterosaur eggs is providing new insights into the species' development, with some containing embryonic remains up to 2 years old. The findings suggest that newborn pterosaurs needed parental care and likely participated in colonial nesting behavior.
A new study challenges previous estimates of US livestock methane emissions, suggesting a significant discrepancy between top-down and bottom-up approaches. The researchers used a spatially explicit approach to estimate enteric methane emissions for cattle and manure methane emissions for swine and poultry.
A study by Embry-Riddle Aeronautical University researchers found that solar radio emissions can degrade 5G network transmissions by up to 15% in hot weather. However, effective communication links are possible at distances of up to 134 meters indoors and 110 meters outdoors, even in hilly urban areas.
Kinase inhibitors show promise in treating various types of blood and lung cancers by blocking overactive enzymes that control cell growth. Researchers identified new target structures for drugs, including the kinase MELK, which is linked to poor prognosis in lung cancer.
A study published in the American Journal of Human Genetics reveals that earlobe attachment is influenced by an interplay of at least 49 genes. This complex genetics challenges traditional teaching methods, which often focus on dominant and recessive genes.
A new study using advanced MRI techniques has discovered disrupted brain connectivity in obese adolescents, affecting regions involved in appetite regulation. The findings suggest a possible underlying cause for the rising rates of childhood obesity and its associated health risks.
A study published in Addiction found that low- and high-volume prescribers both play a significant role in opioid prescriptions, challenging the focus on 'pill mill' doctors. The study also identified other high-risk patient groups, such as concomitant users and chronic high-dose users, who pose a greater public health threat.
A new study found that stressed newborn babies exhibit a heightened brain response to pain, but their behavior remains unaffected. This dissociation between brain activity and behavior has implications for pain assessment in infants.
By forcing light to go through a smaller gap, researchers have increased its intensity and allowed photons to interact more strongly over a short distance. This technology brings optical processing closer to electrical transistors, potentially solving the problem of nonlinear optics and enabling faster, more efficient computers.
Scientists found that parasitic nematodes use odors from host mice as cues to position themselves where they have a higher chance of being eaten. The worms are attracted to fresh mouse feces and can migrate towards new hosts based on odorants produced by mammalian skin, feces, or urine.
A Loyola University Chicago study has identified the protein bicaudal D2, which facilitates the trafficking and nuclear import of HIV-1 genomes during infection. This finding raises the possibility of developing a drug that would prevent HIV-1 from binding to bicaudal D2.
Researchers propose using gravitational wave experiments to detect merger events at redshifts greater than 40, which could indicate the presence of primordial black holes or non-Gaussianity in the early universe. A detection would bolster theories about dark matter, while a non-detection would cast doubt.
Researchers at the University of Houston have developed a new way to understand how the brain controls walking in complex environments. Using brain-body imaging and motion capture technology, they identified specific areas of the brain involved in locomotion, including the posterior parietal lobe and sensorimotor cortex.
Australian researchers have developed a new risk scoring system for children with leukaemia based on missing DNA fragments or 'microdeletions'. The study tested 475 patients and found that the new score is more accurate than the current approach, allowing doctors to better predict relapse risk.
The University of Huddersfield and STFC are working on the RF distribution system for Europe's €1.8 billion European Spallation Source, a particle accelerator expected to be in full use by 2023. The project aims to produce high-intensity neutrons for atomic-level investigations of materials.
A new dual-purpose drug delivery device, SCHIELD, aims to provide long-acting contraception and HIV prevention for women in low- and middle-income countries. The device, set to be launched in Kenya and South Africa, has the potential to improve health outcomes and empower women.
A study found that microRNA-31 accelerates intestinal stem cell growth, potentially leading to bowel cancer. The molecule's levels increased after radiation exposure, suggesting a role in regeneration, while also promoting tumor growth.
Researchers at the University of Cincinnati have developed a targeted treatment that can prevent the spread of pancreatic cancer and protect the heart from damage. The treatment, which involves using an mTOR kinase inhibitor, has shown promise in reducing disease progression and cardiac impairment in patients with certain types of tumors.
Recent studies present promising methods for early HIV identification and treatment, including self-testing and expanding antiretroviral therapy eligibility. Researchers also explore curing HIV using stem cell transplantation and discuss the ongoing growth of the Russian HIV epidemic.
Researchers found that mindfulness training and therapy can mitigate the decline in cognitive abilities and impulse control associated with prison time. The study revealed that inmates who participated in CBT and mindfulness exercises showed significant improvements in emotion recognition and impulse control compared to those in a cont...
Grade school children from low-income homes have significantly smaller vocabularies compared to their peers, with a 10% difference in word learning, leading to long-term academic implications. The study suggests that increasing vocabulary through oral methods and visualizing sentence relationships can be effective interventions.
Researchers at the German Cancer Research Center have found that papillomaviruses associated with UV light can promote the development of non-melanoma skin cancer. The viruses affect the stability of host cell DNA, leading to accumulation of UV-related damage. This link has been previously underinvestigated in human biopsies.
A study by University of Illinois researchers found that individuals with higher news media literacy are less likely to endorse conspiracy theories. The study surveyed nearly 400 participants and found that those who know more about the news media are less susceptible to conspiracy theories, regardless of their political affiliation.
A new study identified CRF1 as a master regulator of mast cell activity during stressful challenges, including psychological stress and anaphylaxis. The study showed that mice lacking CRF1 expression were protected against disease, suggesting a potential therapeutic target for treating stress-related diseases.
A clinical trial shows FMT capsules are 96-per-cent effective in treating C. difficile infections, similar to colonoscopy. The pill-based treatment is non-invasive, inexpensive, and has no risks associated with sedation.
Researchers found that SIRT1 stabilizes a mechanism preventing immune cell toxic effects, but its loss accelerates glycolysis and cytokine production. This understanding led to potential new drug targets to strengthen or weaken SIRT1, potentially countering age-related diseases.
Despite losing some 108 square kilometers of forest between 2001-2014, Mozambique's Niassa National Reserve has the potential to support large elephant populations. The reserve supports tens of thousands of elephants and 1,000 lions, making it one of the few places remaining on the planet with large wildlife populations.
The Society for Healthcare Epidemiology of America published a new guidance document for hospitals to respond to infectious disease outbreaks. The document emphasizes the role of healthcare epidemiologists in emergency preparedness and response, providing medical and technical expertise and leading infection prevention efforts.
A new study published in Archives of Toxicology shows that common combinations of low molecular weight polycyclic aromatic hydrocarbons (LMW PAHs) can help spark the development of cancer, even if each chemical is not known to cause cancer alone.
A recent study has created the first atlas of head and neck cancer, revealing the unique structural transition involving cancer cells and normal cells that allows tumors to spread. This finding may have implications for other common cancers as well.
A new guideline for discharge opioid prescriptions after inpatient general surgical procedures could significantly reduce opioid prescriptions. The guideline, developed by researchers at Dartmouth Hitchcock Medical Center, recommends prescribing a certain number of opioids based on the patient's usage the day before discharge.
A study by Columbia University's Mailman School of Public Health found that cigarette smokers are 10 times more likely to use marijuana on a daily basis. The strongest relationship between cigarette smoking and daily cannabis use is among 12 to 17 year olds, who are 50 times more likely to be daily cannabis users than non-smokers.
Researchers found a significant increase in GABA levels and disrupted balance between neurotransmitters in the brains of smartphone- and internet-addicted teenagers. Cognitive behavioral therapy improved these imbalances, suggesting a potential treatment pathway for addiction.
Rutgers psychologists discover that confronting people about bigoted statements can lead to a lasting reduction in prejudice. Confrontation causes individuals to feel bad and consciously avoid repeating such statements, with effects persisting even a week after the initial encounter.
The first large-scale clinical trial of a long-acting injectable medication for HIV prevention in sexually active women has begun. The study will examine whether a long-acting form of the investigational anti-HIV drug cabotegravir can safely protect women at risk for HIV infection.
A team of researchers has successfully recreated Hofstadter's butterfly using quantum simulators, enabling the simulation of exotic electronic conduction properties. This breakthrough could lead to the development of new materials with unique properties.
A recent study found that antibiotics like ciprofloxacin can directly alter the biochemical environment of mouse immune cells during infection, making it harder for them to kill bacteria. This change in environment also led to increased resistance to antibiotics in E. coli bacteria.
Researchers have identified a genetically distinct subpopulation of patients with glioblastoma that is particularly sensitive to drugs like cilengitide. The strategy uses a gene profile alone to predict which tumors are susceptible to αvβ3 blockade, offering a new therapeutic target for precision medicine in brain cancer treatment. Thi...
Tropical Cyclone Ockhi formed in the Northern Indian Ocean after powerful thunderstorms wrapped into its center from the north. The storm was predicted to move northwest and eventually make landfall near Mumbai on Dec. 5.
Scientists at UW-Madison create novel molecular treatment for Friedreich's ataxia, a rare genetic disorder caused by DNA repeats. The 'molecular prosthesis' helps cellular machinery overcome the blockade posed by repeats, restoring expression of the frataxin protein.
Research indicates that being overweight or obese can lead to poorer RA treatment outcomes and higher mortality risk. Studies show that patients with healthy weights are more likely to achieve remission, while those who are overweight or obese face a 25-47% lower chance of sustained remission despite similar treatments.
Researchers at The University of Tokyo's Institute of Industrial Science have developed a semi-transparent solar cell that absorbs red and blue light while letting green through. The new material, based on perovskite, is able to retain an impressive power conversion efficiency of around 10% despite being made much thinner.
A team of scientists used supercomputers to explore the optical properties of plasmonic nanovesicles, which could lead to breakthroughs in cancer treatment and studying the nervous system. The researchers designed golden nanopills that can be triggered by laser light to release drugs or molecules.
A six-year program will provide multidisciplinary training to tackle urban and industrial runoff challenges and promote ecofriendly approaches to managing water and residual effluents. The grant supports INRS' Decontamination and Reclamation research area and ties in with NSERC's priority fields of environmental science and technology.
Researchers studied African populations, finding a high degree of variability in skin pigmentation that cannot be explained by just a few genes. The study suggests that multiple genes contribute to the process, with variations increasing near the equator.
Researchers have identified a communication network between lung tumors and bone marrow that contributes to tumor progression. Tumors activate osteoblasts in the bone marrow, leading to the production of immune cells that promote cancer growth.
Researchers have developed a method to detect hydrohalite, a substance that forms on treated icy roads and cannot be removed by conventional salting. Using Raman instruments fitted with lasers, trucks can identify the presence of hydrohalite and switch to alternative de-icers, making roads safer for users.
Researchers at Clemson University used a simple computer model to calculate the elastic properties of amorphous diamond, a new form of diamond with varying fractions of sp3-bonded carbon. The results show that this new substance retains desirable mechanical properties similar to crystalline diamond.
A new study sheds light on the origin of the SARS virus, finding that genetic recombination between viral strains in bats may have produced the direct evolutionary ancestor of the strain that caused a deadly outbreak. The study also identified strains capable of entering human cells.
Researchers at Beth Israel Deaconess Medical Center have shown that chemotherapy-generated debris can stimulate tumor growth, but resolvins can suppress this effect. The findings offer a novel treatment approach to prevent cancer recurrence.
The phase III clinical trial showed that fremanezumab reduced the number of headache days by an average of 4.3 days with quarterly treatment and 4.6 days with monthly treatment. The therapy also demonstrated a favorable safety profile, with most common adverse event being irritation at injection site.
Recent genomic analyses have flipped between whether sponges or comb jellies are the oldest lineage of living animals. New research by Professor Davide Pisani reveals that sponges are the most ancient lineage, with models that describe the data poorly favouring comb jellies and those that better describe the data favouring sponges.
Researchers have demonstrated a new method to produce biotemplated nanoswimmers using bacterial flagella as templates, overcoming high startup costs of traditional approaches. The nanorobots can perform nearly as well as living bacteria and show potential for targeted cancer therapeutics and electronics applications.
New research suggests that stressed newborns may not display typical pain behavior despite increased brain activity in response to pain. The study found a disconnect between brain wave patterns and behavioral responses in stressed babies, highlighting the need for alternative methods to assess infant pain.
Researchers studied brain activity of patients with PTSD using EEG tests and found enhanced responses to deviant tones, correlating with poorer cognitive performance on memory tests. This study may lead to the development of a new neurobiological marker for PTSD diagnosis and assessment of treatment outcomes.
Researchers at Tsinghua University and Nanjing University of Posts and Telecommunications have successfully demonstrated entanglement-based quantum secure direct communication (QSDC) over 500m optical fibers. The system uses novel fiber-based quantum light sources to generate polarization entangled Bell states, enabling secure informat...