A new study published in Journal of Neurotrauma found that traumatic spinal cord injuries can lead to persistent changes in metabolism, blood flow, and oxygenation up to 7 days post-injury. This suggests that current clinical practices may not be sufficient to prevent ischemia-related damage.
A recent study identified 8 new genes involved in epileptic encephalopathy, a severe form of epilepsy combining with intellectual disability. Whole-genome sequencing revealed de novo mutations as the main cause of this type of epilepsy.
A neuroprotective compound has been shown to protect against nerve cell death, depression, and memory problems in a rat model of Alzheimer's disease. The treatment also prevented the development of depression-like behavior and delayed cognitive decline.
A new NSF-funded project at UNC-Chapel Hill aims to make expertise in comparing anatomical or physiological knowledge about different organisms accessible to computers. The project will develop tools for semantic ancestral character reconstruction and enrichment, enabling researchers to study how phenotypes evolve along the tree of life.
Researchers at Johannes Gutenberg University Mainz successfully demonstrated the operation of a four-qubit register comprised of atomic ions trapped in microchip traps. The achievement marks a decisive milestone for scaling up quantum computers, showcasing the potential for entangled states to be created with long-lived multipartite en...
Researchers have developed an accurate approach for monitoring cancer DNA from blood samples, validating the use of blood samples for studying patients' cancer genomes. Nearly 90 percent of a tumor's genetic features can be detected in blood samples using whole-exome sequencing.
Women involved in high-risk sex behaviors have more diverse vaginal bacterial microbiota, a lower abundance of protective Lactobacillus bacteria, and are at higher risk for STIs and HIV-1 acquisition. The study suggests that low diversity vaginal microbiota is associated with less risk of vaginal infections.
Research highlights the need for better nutritional management in chronic kidney disease, where high protein diets may have deleterious impacts on kidney health. A low protein, low salt diet may slow progression and help patients defer dialysis initiation.
Researchers have improved the vertical stability of a superconducting tokamak in Korea, allowing for taller plasmas and exceeding design requirements. The new control system uses advanced sensors and electronics to stabilize the plasma's position, enabling more efficient fusion reactions.
A new study from Lund University reveals that depression among new fathers may be more common than previously thought and often goes undetected. The established screening method for depression in mothers is found to work poorly on men, with symptoms such as irritability and low self-control being overlooked.
Portuguese researchers have identified a crucial defence mechanism used by the malaria parasite to survive inside its host's liver cells. The protein UIS3 binds to LC3, forming a protective shield against autophagy, allowing the parasite to evade the host's cellular defence mechanism.
Researchers at the University of Lincoln have developed two simplified synthetic versions of teixobactin, a natural antibiotic effective against superbugs like MRSA. The new forms retain identical potency as the natural form and can be produced on a commercial scale, overcoming previous limitations.
New research has found that protecting high carbon stock forests can benefit mammal diversity and support biodiversity conservation. The study used camera-trap images and satellite imagery to show a clear correlation between high carbon areas and endangered mammals in Borneo.
Physicists at the University of Queensland developed a new technique to reduce errors in atom measurement devices, boosting precision by exploiting quantum entanglement. This improvement enables more flexible design and operation of these quantum sensors, potentially moving experimental physics into real-world applications.
Researchers develop RNA Capture Long Seq (CLS) method to map non-coding DNA regions, improving gene catalogues for long non-coding RNAs. The new method enhances genomic databases like GENCODE, enabling better understanding of genomic function and its impact on health and disease.
Cognivive's video games aim to enhance spatiotemporal cognitive abilities, building underlying capacity that different skills can draw on, improving real-world problem-solving abilities.
A comprehensive study reveals that displaying calories on menus reduces consumer calorie intake by 27 calories per meal, while retailers respond by offering more low-calorie options.
A study reconstructing climatic patterns in China from AD 1-1911 found long periods of cold and dry conditions associated with epidemic outbreaks. However, the relationship between temperature and epidemics varied across short time scales, highlighting climate's scale-dependent impacts on disease prevalence.
A new study by Emory University researchers found that mandatory state policies are associated with the largest reductions in power plant emissions. The analysis shows that policies with mandatory compliance resulted in an average of 2.6 million metric tons of CO2 emissions per year reduction.
A UCLA-led study reveals that sleep deprivation affects the ability of brain cells to communicate with each other, leading to mental lapses in memory and visual perception. The researchers discovered that lack of sleep also slows down brain cell activity, causing sluggish cellular activity and performance issues.
Countries with underprepared health systems face a faster rise in noncommunicable diseases, requiring targeted investments to reduce modifiable risk factors and increase primary care access. The shift is driven by demographic factors rather than behavioral risks.
Researchers at Bielefeld University's CeBiTec are developing novel methods to produce sustainable compounds using microorganisms, aiming to replace fossil fuel resources in the long term. The center has received €4.8 million in funding for three international cooperative research projects.
Researchers at Harvard's Wyss Institute have developed a method to autonomously grow synthetic DNA strands, enabling the creation of programmable molecular devices. The 'Primer Exchange Reaction' (PER) cascades allow for diverse functions such as self-building DNA-origami and sensing environmental signals.
A new HCI study reveals that a two-drug combination significantly reduces precancerous polyps in FAP patients, leading to near-complete blockade of cancer growth pathways. The treatment also activates immune responses aimed at destroying pre-cancerous polyps.
A new study published in Nature Cell Biology shows that human stem cells can be used to produce insulin-producing cells that can be transplanted into diabetes patients. The development of these cells depends on their sense of direction and polarity, which can be controlled using a specific signal pathway.
Astronomers have detected the second most distant star-forming galaxy in the universe, born 12.8 billion years ago, using the Large Millimeter Telescope (LMT). The galaxy is one of the first massive galaxies to form and was observed with high precision using millimeter waves.
The G7 Ministerial Meeting on Health emphasized the need for urgent strategies to mitigate and adapt to climate change's impact on health. Reducing emissions and reinforcing surveillance systems were identified as key measures to adopt globally.
Researchers at UC Davis are part of a NIH initiative to make biomedical data accessible online. The goal is to accelerate discoveries by making research data FAIR, findable, accessible, interoperable, and reusable.
A new study finds that a 70-year-old malaria drug can block immune cells in the liver, allowing nanoparticles to reach cancer cells. The research showed improved drug delivery to breast tumors and accumulation in mouse tumors and lungs.
A new AI system can analyze a large dataset of research papers to extract recipes for producing specific materials. The system can identify paragraphs containing recipes and classify words within those paragraphs according to their roles, allowing scientists and engineers to access detailed instructions for material production.
A study by Hospital for Special Surgery found that a free telephone support and education program for people with lupus has a positive impact on their lives. The LupusLine service, established in 1988, provides callers with solid support from trained peer counselors.
Researchers investigate whether N95 respirators offer protection against fine particulate matter and its associated health risks, including heart disease, stroke, and respiratory problems. The study aims to provide evidence for effective interventions in high-pollution areas.
A recent study has identified Neuregulin 4 (Nrg4) as a key driver of nonalcoholic steatohepatitis (NASH) progression. Increasing levels of Nrg4 protected liver cells from metabolic stress in mice, while loss of the hormone led to accelerated disease progression.
The TUM Nano-CT system produces images with resolutions up to 100 nanometers, allowing investigation of individual muscle strands in velvet worm legs. The device has potential applications in biomedical research and medicine, enabling non-destructive examination of tissue samples and clarification of tumor malignancy.
Tropical Depression Nineteen formed in the Central Atlantic Ocean despite wind shear conditions, according to NASA's Terra satellite imagery. The National Hurricane Center expects it to strengthen and potentially become a tropical storm later on Monday.
Physicists at the University of Innsbruck have developed a technique to transfer quantum information between systems encoded differently, enabling local modification of quantum bits. This 'data bus' approach allows for more robust coupling between quantum processors and memories, paving the way for universal quantum computing.
Researchers at Michigan Technological University have discovered that the shape and repetitive organization of building blocks within metamaterials affect refraction, contradicting previous assumptions. This finding has significant implications for the development of devices such as invisibility cloaks and perfect lenses.
A new statistical estimator extracts useful information from decades-old data and citizen science efforts, providing reliable evidence for climate change. This method unlocks valuable historical records and validates observations made by ordinary citizens, revealing the power of citizen science.
Researchers from Brazil and France identify a new target for developing antibiotics against highly resistant bacteria, inhibiting the interaction of two key proteins involved in cell wall elongation. The discovery paves the way for the development of antibiotics with a different action mechanism, offering hope in combating drug-resista...
A study found that Americans largely agree on what makes people feel loved, with small gestures like compassion and snuggling topping the list. Behavioral actions, such as a child snuggling with someone, were seen as more loving than verbal expressions.
The NIH has awarded Jackson Laboratory for its innovative software to improve data sharing in heart disease research. Researchers will now have access to genomic data shared by humans and animal models, enabling them to fast-track their studies.
Researchers develop a new strategy for treating cancer by controlling chromatin packing densities, which determines gene expression and resistance to treatment. The approach has shown promising results in cellular cultures and is now being tested in animal models.
Researchers found that cell-free tumor DNA circulating in the bloodstream correlates with tumor metabolism rather than tumor burden in advanced non-small cell lung cancer patients. This study suggests that circulating tumor DNA may be a reliable biomarker to identify potential unresponsive NSCLC patients before treatment.
A study on chicken embryos reveals that thyroid hormone transporter MCT8 plays a vital role in brain development. The research found that MCT8-deficient cells failed to migrate and proliferate, leading to disrupted brain formation. This suggests that brain lesions associated with a rare neurological disorder may originate before birth.
Researchers at Salk Institute identify Lkb1 protein as key regulator of Tregs, which play a crucial role in preventing autoimmunity and suppressing cancer growth. The discovery has significant implications for developing effective treatments for these diseases.
Climate simulations predict Mediterranean fir forests will be similar to the driest and hottest periods of the late 20th century under a business-as-usual emissions scenario. Warmer growing seasons may benefit some species in moist refugia, but others could face significant growth declines.
A new study by QUT researchers has developed an advanced statistical model to predict when dredging is least likely to damage seagrass. The model can provide up to a fourfold reduction in recovery time and up to a 35 per cent reduction in local extinction risk for seagrass species.
A study found that women with PCOS are more likely to be diagnosed with mental health disorders, including depression, anxiety, and bipolar disorder. The research also showed that children born to mothers with PCOS are at a higher risk of developing ADHD and autism spectrum disorder.
Researchers examine how civilians respond during disasters, highlighting the emergence of 'swarming' collective action. They aim to re-think traditional concepts like preparedness and response to marginalize vulnerable populations.
Scientists found microcolumns in layer V of the cortex, which are synchronized neural activity units. These units could represent an essential computational unit in the brain, similar to parallel computers.
Research by UConn Health scientists found that teens who used marijuana and alcohol heavily were less likely to achieve adult life goals. Heavy teen use of marijuana or alcohol was associated with lower levels of education, reduced full-time employment, and lower social economic potential.
The Wellcome Trust Sanger Institute is sequencing 25 new UK species genomes to aid conservation and understand biodiversity. The results will be made publicly available and lead to future studies on the UK's rich species richness.
Researchers at Kyoto University have developed a device that uses structural color to measure the beating of heart cells, enabling high-throughput testing for pharmaceuticals. This innovation aims to speed up the process of finding good drugs for heart patients and is a significant step towards improving treatment outcomes.
Researchers found high levels of lead and cadmium in 139 and 134 cases, respectively, on drinking glass products, including tumblers, beer and wine glasses. The study highlights the need for safer alternatives and greater industry awareness of toxic substances used to decorate glassware.
Inorganic-organic halide perovskites have distinctive advantages for high efficiency solar cells, with recent breakthroughs in developing efficient hole transport material free PSCs. Significant ion transport has been found to redistribute doping and defects, affecting photoelectric behavior and stability.
A Kaiser Permanente study found that pregnant women who used an interactive website monitored by a clinical expert were more likely to vaccinate their children than those without access. The study suggests websites with interactive components can complement face-to-face clinical interactions and combat misinformation.
Researchers have successfully cultivated the Périgord black truffle in the UK for the first time, providing a breakthrough in the fight against climate change's impact on this luxury ingredient. The truffle was grown in collaboration with local farmers in Monmouthshire, South Wales, using a Mediterranean oak tree as host.
Patients with severe burns who have higher levels of vitamin D recover more successfully than those with lower levels. Vitamin D supplementation may be a simple treatment to improve wound healing and combat infection.
Research reveals obesity is associated with reduced rates of remission and increased rates of disability in RA patients. Effective weight screening and management should be a central feature of RA treatment plans.
A new study suggests that biologic therapies for rheumatoid arthritis during pregnancy do not significantly increase the risk of opportunistic infections in infants. Researchers found no significant difference in infection rates among infants whose mothers used biologics compared to those who did not.