A study published by the American Academy of Neurology found that women taking topiramate during the first trimester had a three times greater risk of giving birth to a baby with cleft lip or palate. The risk was higher for those taking high doses of the drug, and was comparable to lamotrigine.
A social dilemma experiment found that punishment is ineffective in promoting cooperation among players, with players instead replacing defection with punishment. The study suggests that punishment has a demoralizing effect and reduces the incentive to choose cooperation over competition.
A new guideline from Mayo Clinic suggests that exercise can help people with mild cognitive impairment, which is an intermediate stage between normal aging and dementia. Twice-weekly workouts of 30 minutes or less may slow down the progression of symptoms.
A multimodal approach to peripheral intravenous cannula (PIVC) insertion in the emergency department has been shown to reduce unnecessary PIVC placements while increasing their utilization. This program benefits both patients and healthcare services, potentially leading to significant cost savings.
The study provides a quantitative picture of how surface conditions control the growth of palladium nanocrystals. Researchers designed experiments to assess energy barriers on various facets, using seeds with different surface configurations chosen to have only one type of facet.
Researchers have discovered that bacteria can inject toxic proteins into their competitors, causing cell lysis and death, and then acquire antibiotic resistance by incorporating the released genetic material. This ability allows bacteria to rapidly develop resistance to antibiotics, posing a significant threat to patients in hospitals.
A multidisciplinary approach to identify and care for young women with ischemic stroke may lead to improved outcomes. The study proposes creating clinical decision rules, educational campaigns, and preventive strategies to address the unique challenges in this population.
A recent study led by Harvard University researchers found that coral restoration efforts can have a positive impact on fish communities in the short term and over time. The study showed that even after just one week, significantly more fish and a greater diversity of species were present at experimental coral beds.
New research reveals obesity causes durable and harmful changes to hematopoietic stem cell compartment, potentially impacting blood cancer development. The study also suggests lifestyle choices like diet may durably impact blood formation.
A randomized controlled trial found nearly doubling of STI testing in a group using internet-accessed testing compared to face-to-face appointments. E-STI testing should be considered as a complement to existing services, increasing uptake and treatment rates.
Researchers at Tokyo Tech have developed a new Langevin model that predicts low-energy fission more accurately by accounting for the deformation of nuclear fragments. The four-dimensional model fits empirical data better than previous models and has potential applications in radioactive waste containment and nuclear power generation.
A study found that private emergency departments refer patients to public hospitals with public options, resulting in duplicate testing and increased costs. This practice also strains hospital resources and poses risks to patients.
The PLOS Medicine collection addresses diverse topics in the field of STI prevention, diagnosis, and treatment. Researchers investigate vaccine development, online testing services, healthcare provider perspectives, and antibiotic shortages.
A group of authors from IQWiG has contradicted the American Society of Clinical Oncology's conclusion that MammaPrint can identify patients who do not require chemotherapy. The IQWiG analysis found a statistically significant disadvantage of the test for disease-free survival in certain patient groups.
The Kessler Foundation has received a two-year $150,000 grant from the Hearst Foundations to support a postdoctoral fellow in cognitive rehabilitation research. This funding will enable the fellow to use research tools and innovations created by Foundation scientists while focusing on identifying breakthroughs in cognitive rehabilitation.
Osaka University researchers develop an enzyme-driven approach to sticking biological ink droplets together, enabling the 3D printing of highly complex biological structures with a wide variety of cell types. The method overcomes compatibility problems with sodium alginate and results in high viability rates for cells.
Researchers from A Coruña University reject the glacier refuge theory for Iberian brown bears. They found that the Pleistocene lineage was lost and Holocene bears arrived from an unidentified area, likely France, 5,000 years after colonizing Britain.
A pilot study found that noninvasive brainwave mirroring technology significantly reduced symptoms of post-traumatic stress in military personnel. The treatment, HIRREM, improved insomnia, depressive mood, and anxiety symptoms, with durable effects through six months after use.
A recent study found that opioid prescribing for disabled adults is higher outside of large central metro counties, even after accounting for local economic factors. County-level factors such as household income, unemployment rate, and income inequality also play a significant role in determining opioid prescribing rates.
Researchers develop novel method for selective C-H arylation at room temperature, overcoming harsh reaction conditions. The proposed mechanism involves iridium catalyst activation, arylsilane attack, and oxidation of the intermediate to achieve low-energy reaction.
A University of Hawaii Cancer Center researcher has identified a mechanism that drives cancer cells to move during metastasis. The study defines a signaling hub required for cancer cell movement, which may provide new therapeutic opportunities for brain tumors and other cancers.
People with mild cognitive impairment (MCI) may experience improved memory and thinking ability with regular exercise, according to the American Academy of Neurology. The guideline recommends that doctors recommend exercise as part of an overall approach to managing symptoms.
Researchers at Tokyo Institute of Technology have developed a new technique to determine and visualize the three-dimensional structure of individual dopant atoms in semiconductors, correlated with their electrical activity. This breakthrough could support the development of high-performance devices.