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Science News for December 2, 2018


More than half of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma in ZUMA-1 trial

A follow-up analysis of axi-cel-treated patients with diffuse large B-cell lymphoma (DLBCL) reported that 51% were still alive two years post-treatment. The study found that 83% achieved a reduction in cancer activity, and 39% had ongoing responses. CAR-T cell persistence and B-cell recovery were also observed in most patients.