A study involving wild and captive baboons found evidence of antibiotic resistance in their gut microbiomes, even without human-produced antibiotic exposure. The researchers used functional metagenomics to identify resistance genes, revealing a surprising enrichment of Actinobacteria in wild baboon populations.
Women with mammographically dense breast tissue have higher recall and biopsy rates, as well as increased odds of screen-detected and interval breast cancer. The study supports automated measurements as a future standard for breast density classification.
A study of over 41,000 Australians found that women are more particular about the education level of their partners, especially under 40, while men become more selective after age 40. The research suggests that women's preferences for education level increase with age due to cultural associations between education and social status.
A UCI researcher has received a $4.8 million CIRM grant to develop a stem cell-based retina therapy for treating retinitis pigmentosa and age-related macular degeneration. The therapy aims to transplant sheets of stem-cell derived retina into the back of the eye, potentially restoring vision.
Researchers at EMBL Grenoble investigate how Xofluza, a new anti-influenza drug, works and explore possible mechanisms for viral resistance. They found that a specific mutation in the virus's polymerase enzyme makes it less susceptible to the drug.
A study published in Scientific Reports reveals that the Na/K-ATPase oxidant amplification loop plays a key role in aging and may be targeted for anti-aging interventions. Researchers successfully demonstrated the therapeutic potential of pNaKtide, a synthetic peptide, in improving impaired physiological functions.
A new study from the University of Waterloo found that fewer than 50% of recommended food-handling practices were followed by Ontario high school students. The researchers observed significant improvements in thermometer use after a training program, but many students continued to engage in risky behaviors.
Researchers have created the highest-resolution image yet of the Zika virus, providing a detailed atomic model that enables efficient vaccine and antiviral compound design. The discovery was made possible by the stability of the Zika virus compared to its flavivirus cousins.
A recent study published in PLOS ONE found that female presenters receive more polarized comments on TEDx and TED-Ed videos than male presenters. The research team attributed this to historical gender norms and the online community's tendency to respond harshly to women in traditionally male fields.
A new regulatory axis involving the transcription factor Prox1 has been revealed to negatively regulate MMP14 protein levels, which plays a significant role in cancer progression and metastasis. This discovery provides new insights into the mechanisms governing MMP14's function in physiological processes such as wound healing.
The International Journal on Child Maltreatment will publish research on prevention, control and mitigation of child abuse and neglect. The journal aims to present innovative programs and policies for enhancing children's safety and wellbeing.
Researchers found that infants aged 4- to 8-months hold a primary cerebral representation of audiovisual integration in their right hemisphere, with the number of processed materials increasing with experience. This study sheds light on the trajectory of acquiring general knowledge about objects.
Researchers have successfully cultured Treponema pallidum, the bacterium that causes syphilis, using a novel method. The breakthrough, published in mBio, could lead to improved understanding of the disease and the development of new treatments.
A new multi-center study found that patients receiving leadless pacemakers experience overall fewer short-term and mid-term complications than those receiving traditional transvenous pacemakers. Leadless pacemakers completely eliminated lead and pocket complications, including infection.
Researchers discovered that NK cells can kill malaria-infected blood cells when activated by antibodies from people living in areas with high malaria transmission rates. The study provides a new mechanism for creating a malaria vaccine, offering an additional immune response to those already known.
A trial from Niger found that village-wide prophylactic antibiotics significantly reduced the spread of meningitis. The study showed a 60% lower number of new meningitis cases in villages with antibiotic distribution compared to those without, highlighting the effectiveness of mass prophylaxis as an epidemic response.
Insilico Medicine introduces a novel deep neural network architecture called Reinforced Adversarial Neural Computer (RANC) for de novo molecular design. RANC outperforms other methods in generating unique structures and passing medical chemistry filters.
A recent study found that delaying the release of e-book versions of new books does not lead to increased print sales, but can result in significantly fewer e-book sales once the digital version is made available. Consumers tend to stick to their preferred format and platform.
A new study finds that antidepressant use in people with chronic obstructive pulmonary disease (COPD) is associated with a 20% increase in likelihood of death and a 15% increase in hospitalization due to respiratory-related symptoms. The study suggests strong association, but not cause and effect.
Researchers have identified a novel form of calcium signaling called store-operated calcium entry (SOCE) as the key to expressing specific proteins on individual neurons. This discovery has implications for understanding brain development, behavior, and disease, including neurodegenerative disorders such as spinocerebellar ataxia 15.
Researchers found a clear association between the metabolite profile, sugar in diet, and NEC risk. Feeding lactose-containing formula protected piglets from NEC, while corn syrup solids increased risk.
A large-scale analysis found higher relational mobility in North America, Europe, and Latin America compared to Asia and the Middle East, associated with increased personal self-esteem, closeness in friendship, and proactive behavior. Societal threats and subsistence style also influenced relational mobility scores.
Researchers at Brown University discovered that graphene forms sharp, saw-tooth kinks called quantum flexoelectric crinkles, which produce intense electrical charges. These charges can be used to direct nanoscale self-assembly and manipulate biomolecules like DNA.
Research aims to understand neurochemical basis of decision-making in organisms using limited resources. The project will investigate hormone changes in garter snakes during life phase transitions.
Researchers have devised a highly sensitive method to test the chirality of materials, overcoming false positives from competing effects. By using twisted meta-molecules, they separated chirality from sources of error, allowing for accurate measurement and potential applications in fields like telecommunications and pharmaceuticals.
Researchers from Arizona State University study the Ediacaran-Cambrian transition and find a severe marine anoxic event coincided with the decline of early animals. The team integrated geochemical data and fossil records to precisely match evolutionary and environmental events, shedding light on this pivotal moment in Earth's history.
Researchers set limits on neutron star sizes by analyzing billions of theoretical models, refining estimates to within 1.5 kilometers. The study also explores the possibility of 'twin stars' with exotic properties, which are statistically rare and unlikely to be deformed during mergers.
Researchers have developed a new method to diagnose oral squamous cell carcinomas (OSCCs) earlier, using the mechanical properties of cancer cells. By testing the relaxation behavior after stress release, they found that OSCC cells are 'softer' and exhibit faster contraction than benign cells.
Researchers developed a new genetic engineering technique to improve an enzyme's ability to break down biomass. The EASy method enables accelerated evolution of desirable traits in microorganisms, leading to more efficient conversion of lignin into fuels and plastics.
Historical data analysis reveals significant differences in source region contributions to haze under unfavorable weather systems. Policymakers can develop more efficient control plans by incorporating weather system analysis when haze events occur.
Macrophage receptors trigger intestinal contractions, leading to severe diarrhea in cancer patients undergoing chemotherapy. The discovery opens up new avenues for developing targeted treatments for this debilitating side effect.
Researchers discovered that the tumor suppressor protein ARID1A controls global transcription in ovarian epithelial cells, regulating a large set of genes. Its loss causes dysregulation of important cell functions, including DNA repair and cell proliferation.
Researchers highlight tragic case of baby Noah's death due to vitamin D deficiency and advocate for simplified guidance, mandatory monitoring, and food fortification. Current UK recommendations are deemed outdated and overly complex, putting dark-skinned individuals at risk.
A University of Oklahoma physics professor is using a National Science Foundation grant to explore the potential of spatial degree of freedom in long-distance quantum communications and imaging. The research could bring about a revolution in quantum information science by enabling large-scale quantum information transmission.
A new study by researchers from Trinity College Dublin has found that a substantial number of adults over 50 are deficient in vitamin B12 and folate. The prevalence of low or deficient folate status increases with age, and is more common among smokers, the obese, and those from lower socio-economic backgrounds.
A new study published in the Journal of Nutrition Education and Behavior found that food insecurity has a greater impact on behavior problems and poor cognitive outcomes in vulnerable children, particularly those born to single mothers living in urban neighborhoods.
The Journal of Hymenoptera Research published its 64th issue featuring 14 new genera and 29 new species of microgastrine wasps. The team described five new species named after institutions holding prominent wasp collections, including the Canadian National Collection and the South Australian Museum.
Researchers discovered the intrinsically disordered region (IDR) of Ataxin-2 facilitates its association with other pathogenic proteins, contributing to ALS and SCA2 progression. It also plays a vital role in long-term memory formation and rewiring the nervous system.
Scientists investigate how high blood pressure affects the balance between blood flow and neuron activity in the brain. High blood pressure can lead to increased calcium levels in astrocytes, which may trigger inflammation and alter protective mechanisms.
Researchers at UT Health San Antonio used gene editing to decrease repetitive behaviors in mice with fragile X syndrome, an inherited cause of autism spectrum disorders. The approach resulted in significant reduction of symptoms, including digging behavior slowed by 30 percent and leaping behavior reduced by 70 percent.
A study by Dr Kostas Papageorgiou at Queen's University Belfast found that adolescents with subclinical narcissism may be more mentally tough and perform better at school. The research suggests a positive correlation between narcissism and mental toughness, which can lead to improved academic achievement.
A study analyzing WTO trade challenges found 93 regulations were raised over 20 years, with high-income countries challenging 77.4% of low- and middle-income country rules. These challenges can exert pressure on policy makers to design regulations consistent with WTO rules.
Researchers developed a safer component for lithium batteries, improving energy density and reducing safety concerns.
Researchers found a significant increase in specialist referrals among family physicians switching to blended capitation models, highlighting unintended consequences of policy changes. The study's findings suggest that increased referrals may not be entirely necessary and could result in higher costs for the healthcare system.
Researchers at Texas A&M University have discovered how methylation affects DNA's mechanical properties, revealing new insights into how cells behave. The study opens doors to analyzing other types of DNA or RNA modifications and their behavior under different conditions.
A study presented at the SNMMI Annual Meeting found that early treatment of advanced prostate cancer with lutetium-177 radioligand therapy can significantly prolong life, with a median overall survival of 27 months. Patients who received first-line therapy also had the longest survival rates.
The FAU team's award-winning paper focuses on improving the accuracy of ECM performance model and multicore power model to better describe energy properties of processors commonly used in HPC resources. The improved models provide a more accurate view of processors' actual performance under high computational demands.
A study of 230 family SMEs found that involved boards are crucial for innovation, with strategic involvement driving value creation. The researchers highlight the importance of knowledge, competences, and capabilities of board members in promoting entrepreneurial attitudes.
Hollings Cancer Center researchers discovered that cancer cells protect their telomeres from damage to prevent cell death, contributing to their long lifespan. By inhibiting this mechanism, the researchers hope to develop a new treatment for cancer and potentially delay aging.
A new study found that an experimental drug called AZ32 selectively sensitizes brain tumors to radiation, extending the survival of mouse models with human glioblastoma multiforme. The combination therapy forced GBM cells to undergo mitotic catastrophe, leading to cell death.
A new Portland State University study suggests that universities should invest in training graduate students in 21st century teaching methods, which do not compromise research careers. The study found that Ph.D. students trained in evidence-based teaching methods can be competitive researchers, if not better than those who are not.
A new phylogeny of the Pleurodira suborder, including the Yellow-spotted Amazon River turtle, provides insights into the evolutionary history and biogeographical distribution of side-necked turtles. The study found that Pleurodira fossils are scattered across continents, with the oldest species dating back to 125 million years ago.
Researchers found that creating a mild inflammatory response improves a rat's ability to relearn motor skills after a spinal cord injury. This discovery could have significant impact on treating nervous system injuries in the future.
A Baylor University study found that negative behavior has a greater impact on individuals' well-being and relationship satisfaction during stressful life events. The research suggests that low doses of negative behavior can have a significant effect, while further increases in negativity have less impact.
A recent study has found that poor sleep quality is an independent risk factor for atrial fibrillation (AF), which can lead to symptoms like heart palpitations and shortness of breath. The researchers also discovered that disruptions in sleep patterns, such as reduced REM sleep, predict a higher risk of AF.
International researchers led by Tokyo Medical and Dental University investigated the RSRSP stretch of the regulatory protein RBM20, finding it essential for nuclear localization and splicing regulation. The study suggests that phosphorylation of specific serine residues in this region is crucial for RBM20's function.
A new study found that over 2.2 million children aged 5-17 were treated for bicycle-related injuries in US emergency departments between 2006 and 2015. Helmet use was associated with lower head and neck injury rates, but laws enforcement varies by state.
A new study by USC researchers found that high school, middle school, and elementary school students in the US are using JUUL vaporizers to get hooked on nicotine. The discreet devices are being used undetected on school grounds, with over 1 in 25 tweets mentioning their use.
A team at TUM has succeeded in generating ultrashort electric pulses on a chip using tiny plasmonic antennas, operating above the surface and reading them in again. This breakthrough closes the terahertz gap, enabling frequencies up to 10 terahertz.
Researchers found that ultra-high-strength MRI releases high levels of mercury from amalgam fillings, but lower strength MRI does not cause significant leakage. The study suggests further research is needed to evaluate the relationship between high-field MRI and mercury release.