The journal BioTM has released a tribute issue dedicated to Robert Langer and Nicholas Peppas, two biotechnology luminaries whose contributions have shaped the fields of drug delivery and biomaterials. The issue features research articles from their former students and colleagues.
Charité is leading three new EU-funded projects: ReSHAPE, VirtualBrainCloud, and ENDOSCAPE. The ReSHAPE project aims to develop a treatment for transplant rejection using regulatory T cells, while VirtualBrainCloud creates personalized brain simulations for neurodegenerative diseases. ENDOSCOPE develops non-viral gene delivery technolo...
Researchers at University at Buffalo received an $880,000 grant to develop a model of the female reproductive tract for testing drugs delivered vaginally or to the uterus. This project aims to create cost-effective generic equivalents for existing medications, addressing the limited availability of affordable treatment options.
Researchers at UNIGE discovered the identity of Hydra's inhibitor, protein Sp5, which maintains a single-headed adult body and regulates regenerative response. The mechanism has been conserved throughout evolution, suggesting potential therapeutic applications in human tumors.
Scientists at ZSL urge governments to prioritize the conservation of small mangrove patches despite their size, highlighting the critical ecosystem services they provide. The loss of these habitats threatens critically endangered species and coastal communities, and could exacerbate climate change impacts.
Researchers at USTC successfully observe scattering resonances between atoms and molecules at ultralow temperatures, advancing ultracold polar molecules and chemical physics. The new insights aid in designing high precision clocks, powerful microscopes, and quantum computers.
A study found that increased opioid marketing to physicians was associated with higher prescribing rates and subsequent overdose deaths. The analysis, which analyzed industry marketing data and national opioid prescribing and death data, reported $40 million in targeted marketing efforts across over 2,200 counties.
Henry Sauermann's research on crowd science, a field that involves public participation in scientific projects, has been recognized with the 2018 Nelson Prize. The prizewinning paper introduced a conceptual framework to understand and classify such projects.
Researchers have found that fish can be tracked through the analysis of earstones, which record a fish's pace of life, speed through water, and aid hearing. The earstones also reveal how much of their carbon comes from food or water.
A recent Baycrest study found that many older adults being evaluated for memory concerns had mild to severe hearing loss. Addressing hearing issues may mitigate or fix what appears to be a memory problem. Hearing loss is a common chronic condition affecting 50% of those over 65 and 90% of those over 80.
Researchers at Massachusetts General Hospital found that brief happiness exercises can significantly increase in-the-moment happiness for adults recovering from substance use disorders. The study suggests these exercises may be promising tools for bolstering happiness during treatment and supporting long-term recovery.
Researchers have shown that fish otoliths record information on fish metabolism, providing a unique window into how species adapt to changing conditions. By analyzing the carbon isotopes in otoliths, scientists can infer the fish's activity level and metabolic rate, offering new insights into climate change impacts.
Research by Bocconi University finds that public debt increases the cost of capital for innovative firms, forcing them to choose only profitable projects over riskier ones, ultimately affecting national GDP growth. A high public debt can lead to a 4% decline in GDP growth after five years compared to a normal debt level.
New research reveals a link between immune checkpoint inhibitors and the development of musculoskeletal and rheumatic diseases. The most commonly reported adverse events include arthralgia, myalgia, sicca syndrome, polymyalgia rheumatica, and systemic lupus erythematosus.
The UNIST research team has been awarded the Minister of Science and ICT Award for their study on clarifying the concept and scope of Industry 4.0 using big data analytics and artificial intelligence. The team identified key convergence R&D issues, including infrastructure development, AI development, and industrial innovation.
Researchers have developed a high-performance catalyst for converting methane to formaldehyde using nanomaterials and a core-shell structure. The catalyst has a stable structure and high reactivity at high temperatures, increasing efficiency by more than twice as much as before.
Researchers have created biocompatible microrobots inspired by bacteria that can swim through fluids and modify their shape as needed. These devices use embodied intelligence to navigate complex systems without compromising speed or maneuverability.
Researchers have identified a pH-sensitive pocket in the NMDA receptor that can be targeted by redesigned compounds, offering specificity for stroke and seizure treatments. The 94-series compounds show promise in preventing excessive neuronal firing without affecting healthy brain regions.
A recent study published in the International Journal of Hygiene and Environmental Health found no association between exposure to certain chemicals during pregnancy and an increase in blood pressure. In fact, higher exposure to phthalates, BPA, and parabens was linked to a decrease in blood pressure, particularly in the second trimester.
A Japanese research team identified a plant peptide that helps lateral roots grow with the right spacing. The TOLS2 gene was found to be expressed in lateral root founder cells and inhibits their formation, while the RLK7 receptor suppresses nearby cell growth.
Breastfeeding initiation rates increased by 9% among African Americans, narrowing the gap with White women. CHAMPS program adoption led to improved maternity care and evidence-based practices.
Scientists at Sechenov University have discovered a new highly sensitive and quick method for diagnosing kidney cancer using antibodies to a retina protein. The method measures the immune response to arrestin-1, which is synthesized in cancerous cells of kidneys, and has been shown to detect benign growths at early stages.
Researchers found that gut microbiota can convert levodopa into dopamine, reducing its effectiveness in treating Parkinson's disease. The study suggests that the presence of bacterial tyrosine decarboxylase enzyme contributes to this effect.
A new review by UBC researchers found that up to one-third of pregnant women do not believe cannabis is harmful to their fetus. The study suggests that perceptions about cannabis use influence decision-making among pregnant women. Women who used cannabis during pregnancy were more likely to be under 25, unemployed, or have low income a...
Cambridge researchers have discovered that placentas can adapt to function properly despite poor diets or low oxygen during pregnancy, impacting on pregnancy outcomes and lifelong health. This adaptation helps the placenta transport sufficient oxygen and nutrients to the fetus, mitigating complications such as fetal growth restriction.
A new study finds an association between lengthy periods of maternal sleep and late stillbirths, independent of other risk factors. Further research is needed to understand the relationship and its implications for pregnant women.
A large study found no significant difference in liver cancer recurrence between patients treated with direct-acting antivirals for hepatitis C. The treatment was also shown to reduce the aggressiveness of cancer when it did recur. This new data reassures providers that treating Hep C is safe and beneficial for these patients.
Distinguished Professor Ruoff has been recognized by Clarivate Analytics as a probable winner of the physics prize for his work on carbon-based materials, including capacitive energy storage and supercapacitors. He is one of 17 top-tier scientists selected globally.
A pilot study at Brigham and Women's Hospital found that an innovative home-based care-delivery program helped 81% of participants achieve blood pressure control in seven weeks. The program used Bluetooth-enabled blood pressure devices and patient navigators to facilitate rapid assessment and medication adjustments.
Researchers found NGF has therapeutic properties for diseases like cutaneous ulcers, glaucoma, and Retinitis Pigmentosa. Early studies led to the development of safe dosages and new treatment routes with NGF-based therapy.
Researchers have made a breakthrough in treating nerve damage by combining neurosurgical repair with gene therapy, which stimulates the survival of nerve cells and regeneration of nerve fibers. The discovery is an important step towards developing a new treatment for people with nerve damage.
A Brown University study found that fentanyl test strips are effective in reducing overdose risk, with participants using them to test suspicious drug supplies and testing residue at home due to perceived stigma. The test strips also helped participants change their behavior to reduce overdose risk if they detected fentanyl.
UNIST professors Eunmi Choi and Yong Hwan Kim received recognition for their groundbreaking research on remote detection of hazardous radioactive substances. Their innovative technology has the potential to detect radioactivity from tens of kilometers away, revolutionizing radiation detection.
A team of researchers at McMaster University discovered a way to analyze how musicians intuitively coordinate with each other during performances, predicting their movements to convey emotions. The study found that musicians predicted each other's movements more when playing expressively than non-expressively.
Researchers at Salk Institute mapped the genomes and epigenomes of genetically modified plant lines with high resolution, revealing molecular-level changes when foreign DNA is inserted. This study provides new methods for minimizing potential off-target effects in transgenic plants.
Researchers at Max Planck Florida Institute for Neuroscience developed a new method to identify functional properties of individual synapses linking the two hemispheres. They found that callosal inputs and local inputs with similar orientation preference are clustered within the dendritic field, enabling coordinated network activity.
A new study reveals that many European freshwater fish species, especially those in the Mediterranean region, are threatened by climate change. The research identifies regions and species particularly susceptible to rising water temperatures and changing habitats.
A multidisciplinary team of researchers found specific cognitive deficits in individuals with spinal cord injury (SCI), including information processing speed and verbal fluency impairments. These findings support the theory of accelerated brain aging after SCI, with implications for further research and targeted cognitive interventions.
A study by University of Barcelona researchers found that the green turtle reintroduction program in Cayman Islands has successfully recovered the species' population, with a high genetic diversity. The program's success is attributed to careful management and monitoring, ensuring the long-term survival of the species.
Researchers from Empa successfully synthesized chain-shaped molecules between two microscopically small gold tips. The properties of the resulting molecule can be monitored in real time during synthesis, enabling the creation of electrically conductive molecules with atomic precision.
A new study led by St. Jude Children's Research Hospital found that high-risk leukemia patients did not experience improved long-term survival with bone marrow transplantation. Treatment guided by measuring minimal residual disease was associated with better outcomes, with 58% of patients becoming long-term survivors.
Researchers at Washington University in St. Louis have developed a novel membrane technology that purifies water while preventing biofouling using bacterial nanocellulose and reduced graphene oxide. The new membrane can filter water twice as fast as commercially available ultrafiltration membranes and is environmentally friendly.
Researchers investigated the effect of AR inhibitor fidarestat on high-fat diet-induced intestinal polyps in ApcMin/+ mice. The study found that fidarestat reduced the number and size of polyps, as well as inhibited key proteins involved in carcinogenesis.
A new study published in PLOS ONE found that bilingualism does not improve executive functions in children, including remembering instructions and controlling responses. Researchers used a computer test to compare the cognitive abilities of Turkish-German bilingual and monolingual children between ages 5-15.
A new study found that increased marketing of opioid products to physicians is associated with higher opioid prescribing rates and elevated overdose deaths in the US. The research suggests that even low-value payments or subtle marketing tactics can influence physician prescribing patterns, leading to more overdose deaths.
A study by the US Department of Veterans Affairs found that new appointment wait times have decreased at VA medical centers, making it easier for veterans to access healthcare services. The research compared primary care, dermatology, cardiology, and orthopedics appointments in 15 major metropolitan areas.
Saturn's ring system acts as a sensitive seismograph to measure the giant planet's vibrations, enabling scientists to determine its rotation rate. Researchers used wave patterns in the rings to probe Saturn's interior, obtaining the first precise determination of its rotation rate.
Researchers at UNIST have discovered that endotrophin plays a crucial role in producing a pathological microenvironment in liver tissues of chronic liver disease. ETP levels are associated with metabolic dysfunction and systemic insulin resistance, making it a potential diagnostic marker and therapeutic target.
MIT researchers have developed a new NMR technique that enhances sensitivity, enabling the analysis of complex protein structures in minutes. This breakthrough could provide insights into Alzheimer's and other diseases by studying amyloid beta protein and membrane-bound proteins.
A research team at the University of Cologne has successfully performed a variant of the double-slit experiment using resonant inelastic X-ray scattering. The experiment provided valuable information about the dynamic physical properties of solids and proved a fundamental theoretical prediction from 1994.
Researchers from UTA describe a previously unknown species of snake, Cenaspis aenigma, found in the stomach of a Central American coral snake. The discovery reveals unique features that distinguish it from known genera, including undivided subcaudal scales and cup-like structures on its hemipenes.