A study published in Academic Emergency Medicine found that Focused Cardiac Ultrasound (FOCUS) can significantly lower the likelihood of pulmonary embolism (PE) diagnosis in ED patients with suspected PE and abnormal vital signs. The results suggest that FOCUS can be an important tool in the initial evaluation of these patients.
Researchers discovered the structure of ZCCHC4, an RNA-modifying enzyme linked to cancer, enabling structure-based drug design against liver and other cancers. The study sheds light on how this enzyme controls protein synthesis and cell proliferation.
The BfR has developed a digital tool to track product contamination sources, while strategies for reducing Salmonella and Campylobacter infections are discussed. Viral foodborne diseases like hepatitis E and A are also on the agenda.
Researchers from Drexel University review a decade of studies on the air-purifying effects of potted plants and find that natural ventilation is far more effective at cleaning the air than plants. To compete with building air handling systems, it would take between 10 to 1,000 plants per square meter of floor space.
A new study found that regular physical activity, including lighter intensity activities like walking, reduces the risk of hip and total fracture in postmenopausal women by 18% and 6%, respectively. The research, published in JAMA Network Open, analyzed data from over 77,000 participants and suggests that even modest activities can sig...
The Department of Veterans Affairs is investigating the impact of opioids and sedatives on veteran health, with a focus on reducing overdose and death rates. The study aims to identify effective treatment strategies for co-prescribing these medications, which have been linked to increased risks of respiratory depression and suicide.
Research at the University of Manchester shows that tiny vesicles called liposomes can potentially transport life-saving drugs across the brain's blood-brain barrier following a stroke. This breakthrough offers a new way to get vital drugs to the lesions and stop further damage.
High crop density and inadequate fungicides contribute to new disease emergence in ready-to-eat salads. Climate change also plays a role, reducing plant resistance to pathogens.
Researchers developed a novel method using quartz and feldspar grains from the Parnaíba River in Brazil's Northeast region. The analysis reveals significant differences in luminescence between samples from headwaters and lower reaches of the river, reflecting changes in precipitation patterns over the past 30,000 years.
A new study finds that increasing solar and wind energy in California can enhance drought resilience and benefit groundwater sustainability. The researchers developed a trade-off frontier framework to quantify the water sustainability value of solar and wind energy.
A new study highlights the need for governments and industry to act now to develop a robust recycling infrastructure for end-of-life lithium ion batteries. The UK has an enormous opportunity to address this issue, with analysis suggesting eight gigafactories are needed by 2040 to service demand for recycled materials.
The five-year grant, awarded by the USDA, aims to transform nutrition and water use in the poultry industry. Researchers will explore alternative feed proteins, such as microalgae, to improve production efficiency and quality while reducing competition with food sources.
A Finnish hospital analysis found that 59.5% of women with preeclampsia used at least one drug during pregnancy, compared to 35.5% of controls. The most commonly used drugs were antibiotics, hypertensive medications, and paracetamol.
Researchers found that increasing physical activity after a breast cancer diagnosis is associated with a lower risk of death, regardless of pre-diagnosis activity levels. Postmenopausal women who were insufficiently active before diagnosis but sufficiently active after diagnosis had a 50% reduced risk of overall mortality.
Researchers developed a new imaging technique to track maternal blood flow to the placenta, identifying women at risk for complications such as preeclampsia and intrauterine growth restriction. The study found that women with reduced placental blood flow later developed one or more complications.
Researchers found that 3 women with no apparent olfactory bulbs could identify, detect, and discriminate between odors as well as the average person. Their brains had normal structures outside the olfactory system, suggesting alternative glomeruli maps in other brain regions.
Researchers tested an imaging technique to assess cervix stiffness before labor induction, finding it can predict successful outcomes and potentially reduce cesarean rates. The study suggests a new ultrasonic assessment method could replace manual evaluation for more accurate information.
Researchers created a Liver-Chip using Organs-on-Chips technology to predict liver toxicity across species. The platform accurately assesses the liver-specific effects of various drugs on liver cells from rat, dog, and human sources.
Researchers analyzed data from Kichwa community in Ecuador to understand the selection of medicinal plants. The study found that men cited slightly more species than women, while age played a role in identifying plant families, with older participants naming more species.
Researchers found rapamycin modifies blood flow and cognitive decline with aging. The study provides evidence that TOR drives loss of synapses and cerebral blood flow during aging.
Researchers from UCLA, Oxford, and others analyzed 10 industrial applications for carbon dioxide emissions, finding that utilizing CO2 could help the environment by reducing emissions. The study suggests a potential scale of over 10 gigatonnes of CO2 use per year at under $100 per tonne.
A $700,000 NSF grant will help researchers optimize lower limb robotic exoskeletons for patient comfort. The project aims to create a deeper interaction between humans and machines through machine learning techniques and co-learning.
By adding amniotic epithelial cells to pancreatic islet clusters, researchers created more robust
Researchers at Kyoto University developed a machine learning model that reconstructs neuronal circuitry by analyzing brain signal spikes, estimating the strength of nerve connections with high accuracy. The findings, published in Nature Communications, have the potential to elucidate how different brain regions process information.
Researchers at Tianjin University develop a potential-tuned strategy for efficient synthesis of azoxy, azo- and amino-aromatics via aqueous selective reduction of nitroarene feedstocks over a CoP nanosheet cathode. The method yields products with up to 99% selectivity and 99% yield.
Researchers at Georgia State University have made a groundbreaking discovery in catalytic reactions, revealing that nanoconfinement can actually speed up chemical reactions. This finding has major implications for the engineering of new, more energy-efficient catalysts that could save billions of barrels of gasoline every year.
A new control system has been developed to better control wind energy systems, improving efficiency and reducing costs. By decoupling power generation and feedback, the system enables turbines to respond quicker and with less strain on physical components.
Researchers use electrochemistry to synthesize difficult-to-make compounds and reduce waste and toxic byproducts compared to traditional chemical reagents. The ElectraSyn 2.0 module has enabled chemists to access the technology without electronics expertise, but scaling up production remains a challenge.
Researchers solved the domain structure of HPF from Staphylococcus aureus to understand its role in ribosome hibernation. The study identified key amino acid residues essential for protein function, opening doors to new compounds targeting stress proteins.
Researchers found that when déjà vu occurred, subjects experienced a strong 'postdictive' bias, feeling they knew the turn was coming. This bias was linked to feelings of familiarity and hindsight. Déjà vu is often accompanied by intense prediction feelings, but not actual prediction.
A school-based sleep education program may benefit adolescents by reducing insufficient sleep and improving sleep knowledge. The program showed promising results, with participants two times less likely to report insufficient sleep at follow-up.
Researchers develop novel template-directed approach to create hollow metal-organic framework (MOF) capsules for encapsulating soluble active species. The resulting yolk-shell MOF capsules exhibit superior activity, combining the merits of homogeneous and heterogeneous catalysts.
A randomized clinical trial evaluated mailed HPV self-sampling test kits versus standard care reminders for detecting and treating cervical precancers. The study found that the self-sampling kit increased detection rates without a significant impact on treatment outcomes.
Researchers have developed a non-invasive method to visualize kidney disease in live animals using genetically modified mice. They found that a promising chemical found in citrus fruit, G-Hes, reduces inflammation in the kidneys when fed to mice with kidney disease.
A new study examined data from over 15,000 participants and found that playing video games as an adolescent is not linked to acts of violence in young adulthood. The research suggests that competing factors, such as gender differences, may contribute to the observed relationship between gaming and fighting.
A new study suggests that humans' ability to cooperate and share childrearing duties is key to our demographic success. Cooperative childrearing increases the number of children that mothers can successfully raise, leading to faster maturation and increased reproduction.
Researchers at the University of Pennsylvania have conducted the first-in-US trial of CRISPR-edited immune cells for cancer, demonstrating safety and feasibility with three participants. The edited T cells expanded and bound to their tumor target without serious side effects.
Researchers developed an AI framework that learns human design strategies through observation, enabling it to generate new designs without explicit goal information or bias. The AI performed better than humans on average, but its success came without the advantages humans have, such as specific goals and feedback.
A study of 170 people living with HIV/AIDS in Turkey found that younger individuals, wealthier participants, and those working at diagnosis had higher employment rates. Illicit drug use, longer time since diagnosis, and low CD4 T cells counts were negatively associated with employment.
Researchers have identified a new bacteria-killing toxin that depletes cells of ATP, leading to bacterial death. This discovery holds potential for developing alternatives to antibiotics and addressing antimicrobial resistance.
Researchers at Karolinska Institutet developed a new analytical tool to diagnose intellectual disability through whole-genome sequencing, discovering point mutations, structural chromosome aberrations, and expansions. This method was found to be more effective than traditional gene dose array tests in identifying genetic causes.
Cornell researchers have modeled crackling noise in two dimensions, using a combination of mathematical schemes to solve a decades-old problem. The study sheds light on the behavior of avalanches and crackling noise near critical points, making an important step toward a fuller understanding.
A review of 11 studies on cancer patients' sense of taste and smell reveals a reduced taste function, particularly for sweet flavors, associated with lower appetite and caloric intake. Researchers aim to develop strategies to help patients eat well during treatment.
A study found associations between default mode network connectivity and emotion recognition and social integration in individuals with moderate to severe brain injury. Increased prefrontal-temporal connectivity predicted participants' level of social integration, underscoring the importance of brain connectivity metrics in TBI recovery.
Scientists develop a waterproof metal structure, repelled by water after being submerged for long periods, thanks to femtosecond laser patterns mimicking spiders' diving bell webs and fire ants' air-trapping abilities. The unique etching technique traps air within the structure, preserving its buoyancy even when damaged.
Recent analysis examined safety of oral fluconazole and itraconazole in pregnant women, finding slight increases in risk of congenital heart defects and limb defects. Oral agents were not associated with increased risk of overall birth defects.
A team of scientists has developed a synthetic-molecule-based approach to isolate prion proteins in body fluids, paving the way for quick, noninvasive detection. The test also detects misfolded proteins associated with Alzheimer's and Parkinson's diseases.
Researchers found vitamin D influences melanoma cells' behavior by slowing growth and reducing spread. This discovery could lead to new treatment approaches.
Researchers have identified a small genetic imprint of Palaeolithic inhabitants in North African populations, contradicting the theory that recent migrations erased their genetic traces. The study, published in Current Biology, reveals unique genetic imprints and patterns of continuity versus replacement.
Researchers investigated how residence patterns after marriage affect menopause symptoms and age of onset. They found little evidence supporting the theory that women's experiences with menopause vary due to dispersal from their natal home.
The current US reduction strategy for the Detroit River doesn't address Lake Huron, a major source of phosphorus. The new study suggests that reducing phosphorus loads from the remainder of the watershed by 72% is unrealistic without adjustments to the strategy.
Oak Ridge National Laboratory will lead two new projects and collaborate with seven more to enhance the nation's power grid reliability and resilience. The research focuses on developing efficient solutions for hardening the grid against disruption and making it more resilient when events occur.
Researchers developed new techniques to measure heat tolerance in quinoa, a health food rich in essential amino acids. The method uses spectral reflectance indices to assess plant growth under high temperatures, providing insights into grain production and paving the way for breeding more resilient varieties.
Dr. Yamamoto received the prestigious Karl Landsteiner Memorial Award and Lectureship for his work on blood group genes. He has contributed to a better understanding of glycosylation polymorphisms and cancer-specific glycosylation alterations.
Researchers identify protein CaVbeta1E that promotes muscle mass maintenance via GDF5 signaling, counteracting sarcopenia. The study opens a new field of activity in developing therapeutic strategies against muscular decline associated with aging.
A new study reveals that Madagascar's few remaining patches of lowland rainforest host the highest levels of lemur abundance. Human encroachment in coastal areas disproportionately threatens these primates, emphasizing the need for research and conservation management to protect them.
The clitoris activates changes in the reproductive tract to create readiness for sperm to fertilize an egg. Removal of the clitoris may lead to both sexual and reproductive disabilities.
Non-Hispanic black and Hispanic women reported higher pain scores compared to white women during the postpartum period. Despite this, they received fewer opioids and were less likely to receive prescriptions at discharge.
Tropical Storm Nakri, also known as Quiel in the Philippines, has become better organized and more circular over the past 24 hours. Forecasters expect the system to intensify to 50 knots before making landfall in Vietnam on November 10.
A new treatment approach for inflammatory diseases, including sepsis, stroke, rheumatoid arthritis, acute lung injury, and atherosclerosis, has been discovered using nanoparticles. The technology selectively kills 'rogue' white blood cells that drive exaggerated immune responses, while leaving beneficial cells unharmed.