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Science News for October 30, 2019


News about drug delivery

Researchers at the University of Würzburg have discovered how increasing amounts of active ingredients in polymeric micelles reduce their dissolution and solubility. The study aims to improve drug delivery systems by understanding molecular interactions and potential structural changes to enhance absorption and dissolving capabilities.

SourceUniversity of Würzburg·JournalAngewandte Chemie·DateOct 30, 2019

Artificial intelligence learns muscle anatomy in CT images

A new AI tool uses deep learning to automate the segmentation of individual muscles from CT images, enabling the creation of personalized musculoskeletal models. This advancement has significant implications for patients with musculoskeletal diseases, such as ALS, and high-performance athletes seeking to improve their performance.

SourceNara Institute of Science and Technology·JournalIEEE Transactions on Medical Imaging·DateOct 30, 2019

Study calls for screening for drug-resistant E. coli in capsulized fecal transplants

A new study by Massachusetts General Hospital researchers highlights the risk of drug-resistant E. coli infections in patients receiving fecal microbiota transplants, particularly those who are immunocompromised. The study's findings emphasize the need for improved donor screening to prevent transmission of these resistant organisms.

SourceMassachusetts General Hospital·JournalNew England Journal of Medicine·DateOct 30, 2019

How do you know it's perfect graphene?

Scientists at DOE/Ames National Laboratory have found a broad diffraction pattern in high-quality graphene samples, indicating defect-free and uniform layers of atoms. This discovery enables the reliable identification of structurally perfect graphene, a crucial step towards optimizing its properties for various applications.

SourceDOE/Ames National Laboratory·JournalPhysical Review B·DateOct 30, 2019

NIH-funded study suggests acetaminophen in pregnancy linked to higher risk of ADHD, autism

A recent NIH-funded study suggests that exposure to acetaminophen during pregnancy may increase the risk of attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) in children. The study found that higher levels of acetaminophen exposure were associated with a significantly increased risk of both conditions.

Mayo scientists reverse fibrosis in preclinical studies

Researchers at Mayo Clinic have identified a way to slow and reverse fibrosis by targeting a dopamine receptor, which blocks the growth of scar-forming cells. The approach reversed fibrotic processes in lung and liver models, offering a new treatment concept for fibrotic diseases.

SourceMayo Clinic·JournalScience Translational Medicine·DateOct 30, 2019

It takes more than a catchy headline for health awareness campaigns to inspire action

A study published in Lancet Oncology reveals that online popularity of health awareness campaigns does not always lead to increased interest in related health behaviors. Researchers analyzed Google Trends data for specific keywords associated with each campaign and found that only breast cancer-related searches were influenced by the P...

Will lithium-air batteries ever take flight?

Lithium-air batteries offer a maximum specific energy of 3,460 W h/kg, but scientists need to overcome obstacles such as unstable electrolytes and interference from air pollutants. The technology uses oxygen to oxidize a lithium-metal anode and could be powered by a plane's onboard air storage and filtration systems.

SourceAmerican Chemical Society·JournalChemical & Engineering News·DateOct 30, 2019

Preserved pollen tells the history of floodplains

Researchers have found that fossil pollen can be preserved in floodplain soils, allowing scientists to reconstruct past climate dynamics and land use patterns. The study used soil properties such as organic matter concentration and carbon-to-nitrogen ratio to predict pollen abundance, providing a new tool for climate reconstruction.

SourceAmerican Society of Agronomy·JournalSoil Science Society of America Journal·DateOct 30, 2019

Predicting frailty, disability and death

A study by Brigham and Women's Hospital found that irregular fluctuations in daily motor activity can predict increased risk of frailty, disability, and mortality in older adults. The researchers analyzed data from 1,275 participants and found that random activity fluctuations were associated with a 31% increase in frailty risk, 15-25%...

SourceBrigham and Women's Hospital·JournalScience Translational Medicine·DateOct 30, 2019

Quality and use of green spaces may determine their health benefits

Two studies by ISGlobal found that the quality of green spaces influences physical activity, social contacts and emotional well-being. The presence of green space was associated with a higher frequency of physical activity, more time spent performing health-related activities, and increased social contacts with neighbours.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·DateOct 30, 2019

Cannabis use disorder is declining among young adolescents and young adults

Research suggests that the prevalence of cannabis use disorder has decreased among frequent users between 2002-2016, with significant declines observed across all age groups. This decline may be attributed to changes in social attitudes and perceptions of risk associated with cannabis use, as well as increased legalization.

SourceColumbia University's Mailman School of Public Health·JournalDrug and Alcohol Dependence·DateOct 30, 2019

Opioid-related gifts from pharma companies linked to physician prescribing by specialty

A new study found that physicians who received gifts related to opioid medications were more likely to prescribe opioids the following year. The study also revealed significant variability in opioid prescribing across different medical specialties, with primary care physicians and psychiatrists being among those most likely to be in th...

SourceUniversity of Pittsburgh·JournalJournal of General Internal Medicine·DateOct 30, 2019

What makes the Earth's surface move?

A team of scientists found that two-thirds of the Earth's surface moves faster than the underlying mantle, with the surface dragging the interior. The study suggests that the balance of forces changes over geological time, especially for continents.

SourceCNRS·JournalScience Advances·DateOct 30, 2019

Faster heartbeat helps deer mice to survive at high altitudes

Researchers discovered a genetic variant in the Epas1 gene that enables high-altitude deer mice to survive by increasing their heart rate in response to low oxygen levels. This adaptation is also found in Tibetans living at high altitudes, suggesting potential benefits for long-term survival.

SourcePLOS·JournalPLOS Genetics·DateOct 30, 2019

Nanoceramics from the ball mill

Researchers have found a way to produce corundum nanoparticles using simple mechanochemistry in a ball mill, which could lead to more robust and easier-to-manufacture automotive catalysts and ceramics. The production method involves grinding lumps of boehmite in a ball mill for 3 hours and then heating them briefly.

SourceMax-Planck-Gesellschaft·JournalScience·DateOct 30, 2019

Bionic breakthrough

The Utah Bionic Leg, developed by the University of Utah, enables amputees to walk with more power and better balance. The prosthetic limb features sensors, motors, a computer processor, and artificial intelligence that work together to provide assistance during walking and other activities.

In one direction or the other: That is how DNA is unwound

A study published in PNAS reveals that DNA helicases unwind the double strand more easily in one direction than the other, with the speed of unwinding depending on the sequence composition of the bases. This discovery has implications for understanding gene expression and the regulation of cellular activities.

SourceScuola Internazionale Superiore di Studi Avanzati·JournalProceedings of the National Academy of Sciences·DateOct 30, 2019

Twisted physics

A new study reveals twisted bilayer graphene can exhibit superconducting and insulating regions, increasing its usefulness for electronic devices. The discovery is a significant advance in the emerging field of Twistronics, enabling the creation of materials with high-temperature superconductivity.

Tiny swimming donuts deliver the goods

Researchers created microscopic, 3D-printed tori (donuts) coated with nickel and platinum to mimic biological behavior. These 'micro swimmers' can swim in water, respond to signals, and transport particles, potentially delivering targeted drugs or aiding in micromixing.

SourcePenn State·JournalNature Communications·DateOct 30, 2019

Avocados may help manage obesity, prevent diabetes

Researchers have discovered that avocatin B, found only in avocados, counters incomplete oxidation in skeletal muscle and the pancreas, reducing insulin resistance. The study found significant weight loss and improved insulin sensitivity in mice fed with a high-fat diet supplemented with AvoB.

SourceUniversity of Guelph·JournalMolecular Nutrition & Food Research·DateOct 30, 2019

Intensified global monsoon extreme rainfall signals global warming -- A study

A study published in Journal of Climate found significant associations between global warming and intensified extreme rainfall in global monsoon regions, affecting nearly two-thirds of the world's population. Regional characteristics, including aerosols, urbanization, and climate natural variability, also impact extreme rainfall.

Study suggests interventions against frailty

Interventions aimed at reducing obesity, sedentary behavior, smoking cessation, and improving physical activity have the potential to delay or reduce frailty. Age is a strong predictor of frailty, with other variables such as modifiable risk factors like obesity and lower body strength also being significant risk factors.

SourcePLOS·JournalPLOS ONE·DateOct 30, 2019

Study considers double-edged sword of trust in regulatory agencies' monitoring of firms

Researchers found that strong relationships between regulators and firms improve monitoring quality initially, but eventually lead to negligence and collusion. The study suggests an optimal duration for relationships may exist, with mandatory auditor rotation programs potentially reducing failures in some cases.

SourceCarnegie Mellon University·JournalOrganizational Behavior and Human Decision Processes·DateOct 30, 2019

The danger of great gift expectations

A new study found that neatly wrapped gifts lead to higher expectations but lower attitudes towards the gift, while sloppily wrapped gifts yield more favorable attitudes despite representing the same item. Gift givers should consider wrapping time and budget accordingly based on the recipient's relationship.

SourceSociety for Consumer Psychology·JournalJournal of Consumer Psychology·DateOct 30, 2019

Cumulative environmental exposures increase diabetes risk in rural populations

Researchers found that lower environmental quality in rural counties was associated with a higher prevalence of diabetes. In contrast, urban areas showed a stronger link between air and sociodemographic domains. The study's findings suggest a significant impact of cumulative environmental exposures on diabetes risk in rural populations.

SourceUniversity of Illinois Chicago·JournalJournal of Diabetes Investigation·DateOct 30, 2019

Abrupt shifts in Arctic climate projected

Researchers from McGill University project abrupt changes in the Arctic climate and permafrost, potentially leading to increased wildfires. The study suggests a doubling of wildfire severity over one year in regions like the Northwestern Territories and Yukon.

SourceMcGill University·JournalNature Climate Change·DateOct 30, 2019

How are psychiatric disorders linked to infections during pregnancy?

Researchers found that severe infections in pregnant mothers can impair brain development, leading to psychiatric disorders such as schizophrenia and autism spectrum disorders. The study showed immediate and long-lasting effects on neuronal cells, including impaired cortical GABAergic interneuron development.

The financial benefits of being bilingual

A new study suggests that bilingual individuals are less prone to emotional biases when making financial decisions, which could lead to better outcomes in negotiations and investments. The study found that thinking in a foreign language decreases sellers' attachment to their products, resulting in lower prices and improved interactions.

SourceSociety for Consumer Psychology·JournalJournal of Consumer Psychology·DateOct 30, 2019