Researchers found that pairing Abraxane with Intralipid enhances tumor-killing macrophages, reducing cancer growth and protecting organs from damage. The combination also decreases the amount of expensive drugs needed for treatment.
Astronomers detected velocities of both brown dwarfs in a system orbiting each other, confirming the hypothesis that 2M1510 is composed of two brown dwarfs. The discovery provides rare data on the mass, radius, and age of brown dwarfs, allowing for verification of theoretical models.
Researchers at NIST identified acetic acid as a prime suspect in accelerating the degradation of polyamide-based backsheets, which are common in solar panels. The study highlights the importance of interplay between solar panel components in determining their longevity.
A team of Cornell researchers compiled a 'cell atlas' of muscle regeneration, cataloging the activity of almost every type of cell involved in muscle repair. The dataset provides a comprehensive picture of cellular interactions and may lead to improved rehabilitation strategies for patients recovering from muscle injuries.
Researchers discovered rocaglate compounds capable of killing Candida auris, a challenging pathogen with limited treatment options. The compounds inhibit translation initiation in C. auris, leading to cell death, and have potential as a therapeutic strategy for fungal infections.
Researchers found that degrading perineuronal nets improves learning abilities in mice but disrupts memory storage. Children's brains have flexible connections allowing for better learning and recovery from brain injury due to intact perineuronal nets.
Researchers created a new model to account for wine tears' complex fluid structures, which form due to changes in surface tension induced by alcohol evaporation. The study reveals the interplay between gravity, surface tension, and fluid physics leading to these unusual phenomena.
Scientists classify neurons into three classes based on their response to heartbeat-induced brain motion, revealing differences in firing properties and coordination with cognitive waves. This work aims to bridge scales between microscopic cell behavior and macroscopic cognition.
Researchers at Chalmers University of Technology identified Atox1 as a copper-binding protein that facilitates breast cancer cell migration. High Atox1 levels in tumours are linked to lower survival times, suggesting it may be a biomarker for disease aggressiveness.
Graphite has been found to be intrinsically lithiophilic at 500K, contradicting previous conclusions that it was lithiophobic. The study uses ab initio molecular dynamics simulation and shows that surface chemistry plays a key role in the wetting performance of Li metal on graphite.
A study by University of Helsinki researchers identified a gene variant in the regulatory region of the retina responsible for canine blindness in Miniature Schnauzers. The finding provides valuable insights into retinal biology and offers a new model for understanding related diseases, such as retinitis pigmentosa.
Researchers found that biomass fuels derived from grasses like switchgrass and giant miscanthus can reduce carbon emissions by 78-290% compared to petroleum-based fuels. The study suggests that these crops could provide a significant portion of the decarbonization needed to curb global warming.
Researchers find historically rare events in Indian Ocean have become more frequent and intense, with potential dire impacts on Australia's climate. The study uses coral records to reconstruct variability over the last millennium, providing new insights into how the Indian Ocean interacts with ENSO.
A new study by Texas A&M University biologist Dr. Charles Criscione and collaborators reveals that family ties play a crucial role in the survival of parasitic organisms. Brain flukes sacrifice themselves to ensure the survival of their relatives, who co-infect the same ant's abdomen.
Researchers at NREL developed a new formula to boost perovskite solar cell longevity and efficiency by suppressing light-induced phase-segregation. The tandem perovskite/silicon solar cell achieved an efficiency of 27%, outperforming existing silicon-based cells.
A new study found that people who experienced the greatest levels of hardship, stress, and personal loss were five times more likely to experience a lower quality of life, with significantly more health and physical difficulties in later life. Those raised by emotionally cold mothers were also less likely to experience good quality of ...
Excess electrons can shatter carbon-fluorine bonds in PFAS, breaking them down into by-products that may accelerate the process. The discovery offers a potential method to tackle widespread contamination of water supplies across America.
The National Comprehensive Cancer Network (NCCN) has published a list of high-impact measures for assessing quality improvements in cancer care. The recommendations reflect a landscape analysis from leading oncology experts and include endorsement of 15 existing measures and seven new concepts proposed for development.
FAIR Health has launched a groundbreaking website feature that combines clinical and cost information to support seriously and chronically ill patients in shared decision making with clinicians. The new tool offers three palliative care scenarios, including kidney dialysis, nutrition options, and breathing assistance.
Researchers have identified a new target in 'normal cells' for a potential treatment of triple negative breast cancer. Using PIK3Cδ inhibitors, the study found a reduction in tumour growth and improved survival outcomes when levels of the protein were controlled in surrounding healthy tissue.
A study of 46 Finnish Leonbergers found that 15% had severe arrhythmia and 15% had milder cardiac changes, with sudden deaths linked to cardiac arrhythmia. The researchers aim to identify the genetic cause of the disorder to develop early diagnostics, breeding programs, and potential drug therapies.
A new genetic test can identify patients with multiple myeloma who are at 'ultra high risk' of their cancer progressing aggressively early on. These patients have poorer survival rates and are unlikely to benefit from lenalidomide alone, highlighting the need for alternative treatment approaches.
Dereje Agonafer, UTA's Presidential Distinguished Professor, received the Howard University Alumni Award for his distinguished postgraduate achievements. He has supervised over 225 graduate students and has published more than 230 papers on data center cooling and 3D packaging/cooling.
Researchers observed that male macaques were more likely to interact with humans for food rewards, disrupting normal social behaviors and reducing opportunities for positive interactions such as grooming. This disruption can have detrimental effects on the monkeys' health, life span, reproductive success, and infant survival.
A study found that educating people about the impact of same-sex parenting on children reduces prejudices and misconceptions. However, legal issues persist due to a lack of inclusive marriage policies, which can affect same-sex families in separation cases.
Researchers at UT Austin found a correlation between higher median incomes, urbanization, and lower vaccination rates among white, educated Texans. The study identified pockets of high-risk communities in Texas where outbreaks of vaccine-preventable diseases are more likely to occur.
Researchers from City, University of London developed a software tool to simulate glaucoma's impact on daily life, using commercially available head-mounted displays (HMDs). The study found that participants with simulated visual impairment performed tasks slower and made more movements compared to those without impairment.
A graduate student at the University of Illinois has discovered a new treehopper species named after Lady Gaga, showcasing the diversity of this bug group. The newly identified species, Kaikaia gaga, features unusual characteristics, including horned thoraxes and leg hairs, which differentiate it from other treehoppers.
Researchers at UC have discovered a mechanism that could lead to new immunotherapies for patients with head and neck cancers. By understanding how calmodulin interacts with ion channels in immune cells, scientists may be able to develop new treatments to restore the ability of these cells to enter and kill tumors.
The disease-causing virus BYDV manipulates its host plant and aphid vector to create warmer regions for feeding, increasing the vector's heat tolerance. This allows certain aphids to thrive in warmer conditions, posing implications for crop health as the global climate warms.
Researchers found that domestication of crops led to a decline in their ability to form symbiotic relationships with beneficial soil microbes. This loss has negative environmental consequences, including increased fertilizer use and pollution. Reintroducing genes from wild relatives could help restore these traits.
Researchers successfully tested a new magnetic micro wire-based concept for 'smart' composite production, creating multiferroic-class materials with controlled magnetic and electric properties. The new composites are expected to enable the development of highly sensitive sensors for health monitoring devices.
Researchers found varying oxygen isotopic composition depending on lunar rock types, suggesting minimal mixing between the Moon and vapor atmosphere. The data imply Theia formed farther from the Sun than Earth.
A recent study found an exponential increase in bowel cancer among adults under 50, driven by tumors of the lowermost portion of the bowel. The incidence has risen quickly in southern regions, particularly in the South West.
A Michigan State University study found that toxic masculinity can lead to social isolation among aging men, negatively affecting their health and well-being. The researchers suggest an alternative understanding of masculinity can help alleviate social isolation.
A new imaging agent has been developed to identify cancer cells and their supporting compromised cells. The compound binds to activated annexin A2 protein present in many solid tumors, allowing for targeted imaging and potential dual targeting of the tumor and surrounding cells with chemotherapy drugs.
Critically ill patients on mechanical ventilators who listened to slow-tempo music had decreased need for sedatives, fewer days of delirium, and were more awake. The study suggests that music may be a non-pharmacologic treatment option for delirium.
A new study reveals that plants transfer excess energy from chlorophyll to carotenoids, which release it as heat, preventing photodamage. This discovery could help scientists develop new ways to improve crop yields by understanding the natural photoprotection system of plants.
Researchers found that warming temperatures and wetter weather are causing woody plants to spread across tundra and savanna landscapes, transforming unique biodiversity and affecting climate systems.
A research team led by University of Würzburg scientists has found a way to inactivate the cancer protein NP63, which is crucial for squamous cell carcinoma growth. By using a preclinical inhibitor, they were able to switch off NP63's parking ticket remover and stop tumor cells from growing.
Researchers developed SPINS, an inverse design codebase that automates the search for optimal optical and photonic structures. This enables faster design optimization and opens new possibilities for integrated photonics, including photonic neural networks and metasurface optics.
A Columbia study published in Obstetrics & Gynecology found that patients using copper intrauterine devices (Cu IUDs) had a lower risk of high-grade cervical neoplasms compared to those using levonorgestrel-releasing intrauterine systems (LNG-IUS). The study analyzed data from over 10,000 patients and found the diagnosis rate of high-g...
A study of 109,908 non-migrant individuals found that routine childhood vaccination was associated with 0.2-0.3 additional schooling grades among adults, a significant link across socioeconomic and demographic factors. The finding supports the long-term benefits of vaccines beyond health outcomes.
HKU researchers reconstruct water depth changes in Svalbard using fossil Ostracoda, revealing a sudden temperature rise and abrupt sea-level change due to warm Atlantic waters. The study provides the first solid evidence of MWP-1B's relative sea-level change in ice-proximal areas.
New research suggests that higher concentrations of insulin-like growth factor-1 (IGF-1) may be a probable cause of breast cancer. Studies found an association between IGF-1 and breast cancer development, with higher levels linked to increased risk. The findings support a causal role of the IGF pathway in breast cancer development.
A new study published in Radiology found that digital breast tomosynthesis (DBT) improved cancer detection rates and reduced false positives compared to digital mammography (DM). DBT screening detected a higher proportion of poor prognosis cancers than DM, with better visualization of lesions and reduced tissue superimposition.
Researchers at Duke University found that ultra-black butterfly wings achieve light-absorbing properties using a 3-D structure of wing scales, which creates an optical illusion. This study could help design thinner ultra-black coatings for applications like military camouflage and space telescopes.
A recent study on Zika virus found that individuals who thought they knew more about the threat were actually more likely to feel uncertain and anxious. The researchers suggest that public health agencies should focus on providing ongoing updates and shaping messages that encourage people to stay informed, as uncertainty can fuel fears...
Researchers at UNIST developed an ion concentrate electrolyte using a solvent containing fluorine atoms, which protects both the negative and positive electrodes in lithium metal batteries. This new composition increases battery output and lifespan, addressing stability issues with lithium metal batteries.
Researchers at the University of Bath recommend reducing the impact of existing palm oil production and supporting Certified Sustainable Palm Oil to make the industry more sustainable, as alternatives take several years to develop.
Researchers developed a platform to coculture neurons and muscle cells, capturing the emergence of neuromuscular junctions and synchronized bursting patterns. The study provides new insights into biohybrid machines and their potential applications in fields like intelligent drug delivery and environment sensing.
Researchers used headband-mounted sensors on soccer players to collect data, which was confirmed by video analysis. The study found 60% of recorded events were false positives and highlighted the importance of video verification for reliable injury prevention strategies.
A global study found that mangroves provide $65 billion in annual flood protection benefits, reducing flood damages and increasing coastal safety. Mangrove restoration can be easily done and has already been successful in projects worldwide.
A recent study of over 4,500 postmenopausal women diagnosed with breast cancer found that about 1 in 40 have BRCA1 or BRCA2 gene mutations. These mutations increase the risk of other cancers, including ovarian cancer, and may benefit from genetic testing.
Researchers developed a novel approach called MTV-CPR to video record and review CPR practices, leading to improved survivorship rates for cardiac arrest patients. The study found that the use of video recording and team-focused strategy increased the return of spontaneous circulation (ROSC) rate from 26% to 41%.
A recent study by Penn State researchers found that communities with more fast food restaurants, higher population density, and jobs in the extraction industry have shorter life expectancies. Conversely, areas with growing populations, good access to physicians, and high social cohesion tend to have longer lifespans.
The Vilcek Foundation is awarding $150,000 to three early-career immigrant researchers in biomedical science. The prizes recognize emerging professionals who have demonstrated significant accomplishments early in their careers.
By using approximations instead of explicit kernels, researchers have accelerated machine learning speeds and improved AI's ability to handle large datasets. The new approach uses statistics to derive a nearly accurate kernel that can be computed much faster than traditional methods.
Obesity increases levels of peroxynitrite-making enzymes in tiny cell membranes, silencing TRPV4 and lowering calcium entry. This leads to increased blood pressure. Targeting peroxynitrite or enzymes that make it may be an effective way to treat high blood pressure in obesity.
A Kobe University research team developed a method to produce high rates of D-lactate using cyanobacteria, which could lead to the creation of biodegradable plastics. The team used genetic engineering and dynamic metabolomics to optimize D-lactate production, achieving a rate of 26.6g/L from CO2 and light.
Researchers found that bulls fed distillers grains had higher sperm quality and greater body weight, but no significant difference in body fat. The study suggests that distillers grains can be safely used in bull development rations, with minimal impact on reproductive health.
Researchers found that young, first-time sugarcane workers with even slightly lower than average kidney function were at a greater risk for rapid onset of kidney injury. The study highlights the importance of routine blood pressure and renal function screenings for workers in high-risk occupations.
The Amazon rainforest could disappear within a lifetime if a tipping point is reached, according to new research. Ecosystems dominated by single species are more stable and take longer to shift, while the loss of key species like elephants can trigger rapid changes.
A new study reveals that children and teenagers worry about political issues, with concerns spanning environmental issues, gun violence, and racial/ethnic minorities. While the worry may not be harmful in moderation, caregivers of youth with anxiety disorders should be aware of its potential impact.
Researchers created a new acoustic smart material inspired by shark skin that can mimic three key electronic devices: a switch, logic gate, and diode. The material changes its properties in response to magnetic stimuli, allowing for on-demand transmission and switching.
Researchers at the University of Warwick found that leaving babies to 'cry it out' does not affect their behavior or attachment, but may actually help them learn self-regulation and reduce crying duration. Parents who adapt to their baby's needs and wait before intervening can provide a safe space for their child to develop.
Researchers at IAS and University of Michigan propose QCD axion as solution to cosmological excess of matter over antimatter. The QCD axion could explain three missing pieces of physics puzzle, including the strong CP problem and dark matter.
A study found that low-dose chest CT scans used for lung cancer screening do not cause significant DNA damage or chromosome aberrations. The results suggest that the risks of low-dose CT are minimal, and it can be used for lung cancer screening.
Researchers discovered how electrons in pyrochlore oxide crystals form a 'glassy state' due to distortions in the atomic lattice, leading to a spin-glass phenomenon. This work sheds light on understanding glass transitions and their fundamental role in physics.
A 12-week study found that daily avocado consumption improved attention in adults with overweight or obesity, as measured by the Flanker task. However, there was no significant impact on other cognitive tests or lutein levels
Researchers found that hydrogen ice pellets enhance fusion temperatures and plasma pressure compared to gas injection on DIII-D. The findings are encouraging for ITER's pellet-injection fueling method, which aims to replicate the sun's fusion process.
Researchers have successfully mapped the cosmic web's filamentary structure using a slime mold-inspired algorithm, providing insights into dark matter's role in shaping the universe. The study revealed that denser regions of intergalactic gas are organized into filaments that stretch over 10 million light-years from galaxies.
Researchers developed a new concept of resectability and identified objective pre-operative prognostic factors to predict long-term survival in pancreatic cancer patients. The study's nomogram can estimate patient outcomes before surgery, regardless of local anatomic features.
Researchers at the University of Birmingham found a clear relationship between infant sleep problems and emotional and behavioral problems in toddlers. Infants who experienced frequent night wakings, short sleep duration, or difficulty falling asleep were more likely to show emotional and behavioral problems by 24 months.
Researchers use a Physarum-based algorithm to visualize the cosmic web's filaments, connecting galaxies and diffuse hydrogen gas. The model replicates the distribution of dark matter on large scales, providing a new tool for understanding the universe's structure.
A novel biofuel system has been developed for hydrogen production from biomass, improving efficiency and reducing energy consumption. The system uses lignin as an electron donor to produce high-value-added compounds and extract electrons for hydrogen production.
Research reveals large ecosystems like Amazon forests can collapse in 49 years and Caribbean coral reefs in just 15 years. This accelerated rate of transformation is attributed to the modular structure of larger ecosystems, which initially provides resilience but ultimately accelerates unraveling when a threshold is passed.
Researchers at Drexel University have developed a lab-scale reactor system that can produce large quantities of MXene in bulk, preserving its unique properties. The system uses a computerized process to refine the material and ensures consistency, a critical step towards achieving manufacturing standards.
A new project aims to bring together academic, clinical, and community partners to improve access to healthy local foods for Latinos in rural communities. The UC Riverside School of Medicine will lead the two-year engagement project, which includes a cookbook and training of health educators to promote MyPlate recipes.
A new study published in the Journal of Nutrition Education and Behavior confirms that frequent family meals are associated with better dietary outcomes and improved family functioning. The research found a positive relationship between family meal frequency and increased fruit and vegetable consumption, as well as measures of family c...
New research from the University of Cambridge suggests that parents of children with genetic learning disabilities are at risk of mental health problems. The study found that social factors do not predict a parent's risk of low mood and stress, instead highlighting the impact of the child's genetic disorder and behavior on family life.
A study published in Injury Prevention found that around 100,000 convicted felons in the US may still possess firearms, with California being the only state to enforce a recovery program. The researchers estimate this number is based on data from the Armed and Prohibited Persons System database.
Researchers have found the first direct correlation between dark matter and gamma rays in the universe. The study used gamma ray data from Fermi Large Area Telescope and mapped it with weak gravitational lensing, providing insights into the nature of dark matter and its potential connection to gamma ray emissions.
A new study by Case Western Reserve University found that nearly 94% of defendants in Cuyahoga County drug court have been exposed to trauma, with many suffering from post-traumatic stress disorder (PTSD) symptoms. The research suggests a need for increased trauma-informed care and possibly specialized, gender-specific support.
Chemists at the University of Miami have created an artificial enzyme with improved catalytic abilities. The new molecule is designed to tackle chemical reactions in industrial settings and could lead to the development of more efficient biofuel production, drug creation, and other applications.
Researchers found that intermittent fasting affects liver enzymes and fatty acid metabolism in mice, revealing a surprising role played by the HNF4-alpha protein. This knowledge can help develop new interventions for cancer, cardiovascular, and diabetes diseases.
A new study analyzed temporal evolution of seismicity and growth of maximum observed moment magnitudes in various stimulation projects. The results show a clear linear relation between injected fluid volume and cumulative seismic moments for most projects, indicating that seismicity can be managed by changes in injection strategy.
Researchers at KU Leuven exposed a security flaw in Intel processors, revealing a vulnerability in SGX enclaves that can be exploited for sensitive information. The 'Load Value Injection' attack allows attackers to inject data into software programs, compromising passwords and other personal data.
Researchers identified a mutation responsible for destabilizing light chains, leading to the formation of deadly amyloid fibrils. The study provides new insights into the disease and potential diagnostic methods.
A new classification system for orofacial pain has been developed by international researchers, providing a common language for medical doctors and dentists to diagnose patients accurately. The system is expected to improve treatment outcomes for individuals suffering from chronic pain in the mouth, jaws, and face.
Sandia National Laboratories has received funding to develop a patient-friendly brain imager that uses quantum sensors for more accurate and accessible measurements. The new system aims to enable people with chronic pain and motor disorders to participate in MEG scans, improving the accuracy of diagnoses.
Researchers used CRISPR-Cas system to effectively target and eliminate specific gut bacteria, including Clostridioides difficile, the pathogen that causes colitis. The study demonstrates the potential of this approach in preventing disease and promoting human gut health.
Young people who have tried e-cigarettes but never smoked before are four-and-a-half times more likely to go on to try smoking. However, the association between e-cigarette use among non-smokers and subsequent smoking remains unclear due to methodological limitations.
Research shows that babies consuming infant rice cereals have higher intakes of key nutrients like calcium, magnesium, iron, zinc, and vitamin E. Baby cereal is associated with better nutrient status and a reduced risk of inadequate intakes of these essential nutrients.
Researchers identified a novel L-fucose metabolic pathway in Veillonella ratti, which encodes enzymes for a previously unknown non-phosphorylating L-fucose pathway. The study also discovered another L-2-keto-3-deoxyfuconate aldolase involved in the same pathway in Campylobacter jejuni.
A new clinical trial led by Keck Medicine of USC is investigating the effectiveness of Transcutaneous Electrical Spinal Cord Neuromodulation (TESCoN) in treating overactive bladder due to neurological conditions. The trial aims to improve patients' sense of well-being by enhancing bladder control and reducing symptoms.
A study by the UPV/EHU-University of the Basque Country found that microplastics cause mortality in detritivores and reduce tadpole growth. Microplastics also attach to periphyton, altering ecosystem productivity, and are ingested by organisms, highlighting their potential impact on freshwater ecosystems.
Researchers have developed a novel error-correction scheme that takes advantage of bosonic symmetry to encode information efficiently. This approach could reduce the number of physical qubits required, enabling the scaling up of experimental quantum computers.
Researchers at Northwestern University discovered a new way to reduce frost formation on any surface using a leaf-inspired design. The study found that the optimized surface structure reduces frost by up to 60% and can be defrosted with considerably less energy.
Scientists at King's College London have found positive evidence that a natural tooth repair method has the potential to be translated into a clinical approach. The study discovered that reparative dentine produced is sufficient to repair cavities in human teeth, and the drug can activate repair up to ten times larger.
Researchers propose axion as solution to three mysteries: matter-antimatter asymmetry, dark matter, and the strong CP problem. The axion's rotation creates a tiny excess of matter over antimatter, explaining why we exist.
A study of a second HIV patient to undergo successful stem cell transplantation from donors with a HIV-resistant gene finds that there was no active viral infection in the patient's blood 30 months after they stopped anti-retroviral therapy. The patient had a healthy CD4 cell count, suggesting they have recovered well from the transplant.
Researchers found that baboon mothers in the wild carry dead infants for varying lengths of time, with an average duration of three to four days. The mother's age, infant cause of death, and climate conditions may influence the length of time a mother carries her dead infant.
Scientists have identified a specific antibody that binds to brain immune cells and triggers processes that enhance microglia activity. This stimulates the immune cells to detect and degrade abnormal protein deposits, known as plaques, more effectively, potentially providing better protection against Alzheimer's disease.
A new study published in Circulation found that noncitizens in the US are less likely to receive treatment for cardiovascular disease risk factors due to lack of insurance coverage and a usual source of care. The disparities were significant, with only 16.5% of noncitizens receiving treatment for high cholesterol.
Self-help groups have empowered caregivers of children with disabilities to take control of their lives and reduce challenges in low-income settings. The UEA-KEMRI project demonstrated significant growth in social support and caregivers' sense of well-being.
A UNIGE researcher has solved a scientific controversy about the speed of the universe's expansion by proposing that it may not be homogeneous on a large scale. This approach eliminates a divergence between two independent calculation methods, which previously yielded conflicting values for the Hubble constant.
Researchers developed a microfluidics device that isolates cancer cells from urine, achieving high detection rates of up to 85% and 86% for localized cancer cases. The new method provides an alternative to invasive tissue biopsies and blood tests with false positive results.
Researchers developed a computer program analyzing molecules in blood plasma to identify individuals at risk of becoming overweight and developing obesity-related diseases. The test is 90% accurate in detecting whether the subject will gain weight without intervention, also predicting diabetes and other health risks.
A University of Oklahoma-led study reveals a decline in grasshopper numbers over the past two decades in a Kansas grassland preserve. The research identifies nutrient dilution as a key driver, caused by increased atmospheric CO2 levels, leading to declining plant quality and reduced sustenance for herbivores.