Experts recommend prioritizing patient safety with telemedicine and remote monitoring, while minimizing exposure to COVID-19. Delaying treatment by just 15 minutes can significantly impact recovery outcomes.
Castleman Disease patients experience a cytokine storm that can cause fever, organ failure, and death. Researchers identified Type-I Interferons as highly active during flares and the JAK pathway as a critical mediator of the immune system's hyper-response.
A bioethicist has sounded the alarm about unlicensed and unproven stem-cell-based 'therapies' being marketed for COVID-19 prevention and treatment. These businesses are taking advantage of hope and desperation, but rigorous clinical trials have not been conducted to establish their safety and efficacy.
The benthic biomass on the continental shelf of the Antarctic Weddell Sea declined by two-thirds between 1988 and 2014, with a drastic change in composition. The study's findings indicate that increased sea-ice cover and thicker snow cover have concrete negative effects on benthic organisms and ecosystem productivity.
A clinical trial found that olanzapine significantly improved patient quality of life by reducing nausea and vomiting scores. The study showed that patients who received olanzapine reported less vomiting, better appetite, and better well-being compared to those who received a placebo.
A clinical program was co-created by autistic transgender youth, their families, and clinical experts to support the specific needs of this population. The model includes three key components: building community, introducing role models, and supporting gender expression through coaching.
Researchers at ICFO have developed a new photothermal sensitizer using tungsten oxide nanoparticles, enabling the production of high-color-purity 3D objects and overcoming previous limitations. The new method allows for efficient and cost-effective fabrication of complex geometries with precise color control.
Francis Macdonald and colleagues used thermochronology to track rock movement, finding evidence that supercontinent processes drove erosion between 1,000 and 720 million years ago
Researchers analyzed DNA of 89 ancient humans in the central Andes, finding early genetic differences between regions and surprising continuity. Genetic analysis revealed a north-south substructure of the Highlands developing by 5,800 BP, with minimal changes to the genetic structure of the central Andean region between 2,000 and 500 BP.
A new prediction tool developed by University of Nevada, Reno researchers can help manage forests in the Sierra Nevada mountains. The tool, designed to focus on water quantity, predicts how different approaches to thinning impact snowpack accumulation in Lake Tahoe.
The collaboration provides new insights into Jupiter's turbulent weather, including the association of lightning outbreaks with specific cloud structures. The team maps lightning flashes onto optical images, revealing a three-way combination of clouds and clear regions that facilitate convection and energy release.
A study published in Nature Communications suggests that clay layers do not always protect groundwater from arsenic contamination. In fact, distant municipal pumping can trigger the release of arsenic below such clay layers, putting thousands of people at risk in Bangladesh and potentially other regions worldwide.
Patients who visited the emergency department for an opioid overdose are 100 times more likely to die by drug overdose in the year after being discharged. Those who experienced a sedative/hypnotic overdose had overdose death rates 24 times higher and suicide rates 9 times higher than the general population.
A study examining factors affecting racial disparities before kidney transplantation found that socioeconomic status and comorbidities explain up to 58% of the disparity in listing. Black patients with kidney failure are more likely to be waitlisted than white patients, despite similar rates of transplant receipt.
Researchers demonstrate a potential solution to corneal scarring by using stem cells to regenerate the cornea's stroma. The study shows improved corneal transparency and vision with minimal inflammatory response.
Scientists successfully produced a photoanode with extremely high conductivity by annealing hematite mesocrystals to a transparent electrode substrate. This enabled the separation of electrons and holes quickly, promoting the oxidation reaction and achieving the world's highest solar water-splitting performance.
A study comparing opioid-related deaths in cancer survivors to the general population found that opioid-associated deaths in cancer survivors have increased at a rate similar to that of the general population. The findings suggest that opioids may not be contributing to rising rates of overdose among cancer patients.
Researchers from the University of Tsukuba have synthesized branched polymer crystals that can be used as tiny laser sources, overcoming dendrimers' fragility and poor crystallinity. The new material exhibits lasing properties and shows promising potential for applications in displays and micro-optical circuits.
New research suggests that sleep problems in babies may be associated with altered growth trajectory in the hippocampus, a key part of the brain involved in learning and memory. Infants who later develop autism were more likely to have difficulty falling asleep, which was linked to changes in the size of the hippocampus.
Researchers developed a new process to combine multiple disease models for outbreak management, reducing uncertainty and providing better tools for decision makers. The three-part process allows policymakers to evaluate valuable ideas from across the modeling community and identify critical uncertainties to prioritize research directions.
St. Jude awarded a National Science Foundation grant to develop new tools for studying pediatric diseases by integrating biology and engineering at the molecular level. The collaboration will provide St. Jude faculty with a new chemical and engineering toolbox to address gene regulation disorders, including childhood cancer.
A recent GW survey found that only 25% of young adults consider social media a key factor in choosing a dermatologist. Dermatologists can still leverage social media for patient engagement and education, but it should be used alongside other methods to recruit new patients.
Researchers from Skoltech and German partners measure the electrical conductivity of pure interfacial water, finding it five orders of magnitude higher than bulk water. The discovery sheds light on complex fluids and has implications for electrochemical energy systems, membrane technologies, and nanofluidics.
Clemson scientist Matthew Koski will advance his research on floral thermoregulatory mechanisms with a 3-year, $455,000 grant. He aims to understand how flowers adapt to climate change by studying their thermal environments in Colorado.
The updated guidelines reflect a shift towards outpatient care and non-emergency surgery for left-sided colonic diverticulitis. Key findings include the preference for minimal colectomy approaches when expertise is available, and an increased focus on evidence-based recommendations.
Researchers develop synthetic chloroplasts using microfluidics and spinach thylakoid membranes to mimic complex natural photosynthetic processes. The system enables light-powered CO2 fixation with potential applications in small-molecule synthesis and carbon sequestration.
Researchers found reduced brain structure and connection in individuals with body integrity dysphoria, linked to feelings of amputation. The study suggests specific brain anomalies may contribute to the desire for amputation, potentially leading to improved treatment options.
A new study in Washington state found that police officers have varying concerns about the legalization of cannabis, including its effects on youth and impaired driving. The study's findings can inform other states' efforts to address legalization.
A study by University of Michigan researchers maps China's export-driven CO2 emissions to specific coastal manufacturing hubs, revealing that 1% of the country's land area generates 75% of these emissions. The findings highlight key sectors and cities driving climate change.
The EU is taking a cautious approach to gene drive organisms, considering their potential risks and benefits. The technology uses CRISPR/Cas-9 genome editing to introduce permanent changes in ecosystems, raising concerns about long-term ecological impact.
A recent study by the University of Bonn found that Brazilian soy exports have a significant impact on the climate, with varying levels of CO2 emissions depending on the location where soybeans are grown. The researchers used Life Cycle Assessment methodology to estimate the carbon footprint of Brazil's soy exports and found that some ...
Global health scholars warn of impending crisis in Africa due to slow access to COVID-19 supplies, echoing the experience during the early stages of the HIV/AIDS pandemic. Several African countries have prepared disease response capacities, but geopolitical power struggles hinder supply acquisition.
Scientists have created a dynamic database driven by AI to collect and analyze coronavirus research, identifying potential druggable sites and assessing treatment efficacy. The Coronavirus-CanSAR platform combines vast amounts of data on viral proteins, interactions with human proteins, and clinical trials.
Researchers have discovered a new method to detect beer and other malted foodstuffs in archaeological finds. By analyzing the aleurone cell walls of ancient grains, scientists found a consistent thinning across five sites dating back to the 4th millennium BCE, indicating malting processes.
Researchers at Linköping University have developed a method to create thin metallic films using free electrons in a plasma, eliminating the need for powerful molecular reducing agents. This innovation enables the production of processors and similar components without the constraints of traditional chemical vapor deposition methods.
Researchers found that winning back lost customers can lead to increased profits, but requires a failure-tolerant organizational culture that encourages open discussion and accountability. Successful reacquisition management also involves establishing guidelines for employees to follow when addressing customer defections.
Research finds UK government's reliance on 'lean production' and 'just in time' continuity planning left NHS stockpiles short of vital supplies and capacity for PPE, ventilators, and testing. The paper suggests a new independent body should be set up to take responsibility for future national emergency preparedness.
A new high-resolution 3D map of the mouse brain has been published, providing a reference atlas for the neuroscience community. The map enables whole-brain studies and improves research by allowing researchers to precisely co-register different types of data, enabling bigger-picture views and comparisons.
A new study reveals that adult comb jellies consume their own offspring blooms as a nutrient source, allowing them to persist in extreme conditions. This behavior enables the jellies to colonize further than climate systems and other conditions would allow, posing a threat to native species.
A small NIH-funded study suggests that early sleep problems may further raise the likelihood of an autism diagnosis among at-risk children. The study found that high-risk children who met criteria for ASD scored higher for sleep problems and had more growth in the brain's hippocampus region.
Researchers at Johannes Gutenberg University Mainz have developed a non-contact method for detecting the state of charge and defects in lithium-ion batteries. The technique uses atomic magnetometers to measure the magnetic field around battery cells, enabling fast and high-throughput measurements.
Researchers developed a two-region soil-gas diffusivity model to characterize aggregated agricultural soils. The model accurately estimates gas diffusion and provides insights into greenhouse gas emissions.
Researchers investigated semen tests in men infected with SARS-CoV-2, finding notable differences in test results and clinical features. The study revealed distinct patterns of sperm abnormalities and hormone imbalances among these patients.
Researchers developed a compound that significantly reduced amyloid plaques, lessened brain inflammation, and diminished molecular markers of Alzheimer's disease. The findings suggest that drugs targeting different regions of amyloid-beta protein fragments and metal ions could improve outcomes for people with Alzheimer's.
A recent study discusses the parallels between diagnosing and treating cancer patients versus those with COVID-19. Key similarities include the importance of early detection and personalized care plans.
Researchers at Tel Aviv University have developed a new technology to identify and select better-quality sperm cells, which could increase the chances of pregnancy and a healthy fetus. The technology uses light computed tomography (CT) to create highly dynamic 3D maps of sperm contents without cell staining.
A recent study of over 1,400 couples in Italy found that despite lockdowns, most people did not plan to conceive during the COVID-19 crisis. The main reasons cited were economic difficulties and concerns about pregnancy complications. Meanwhile, some 140 people even expressed a new desire for parenthood during quarantine.
The exclusion of children from COVID-19 clinical trials has significant implications for treatment options in this population. Experts argue that including children in these trials is crucial to develop effective treatments tailored to their needs.
A study published in Nature Communications identified an activating somatic mutation in the mTOR gene as a common cause of chronic GvHD. The mutation was found in 2.2% of chronic GvHD patients but not in healthy blood donors, suggesting a potential target for individualized treatments.
An international team analyzed genome-wide data from 89 ancient individuals in the central Andes, revealing early genetic distinctions between groups, population mixing, and surprising genetic continuity. The study provides a comprehensive portrait of pre-Columbian Andean civilizations.
Researchers at Karolinska Institutet and the universities of Jyväskylä and Tampere have produced a vaccine that protects against all six known strains of Coxsackie B virus, which may play a role in triggering type 1 diabetes. The vaccine was tested in animal models and showed promise, with plans to conduct human clinical trials.
A new metabolism regulation system was found in brown adipose tissue using the kallikrein-kinin hormonal system, which can help prevent damaging effects of excessive activation. This discovery could lead to strategies for moderating thermogenic activity in pathological situations like cancer.
Researchers from the University of Tsukuba identified Myc as a central molecular actor in eliminating damaged germline cells to preserve germline integrity. Knockdown of Myc resulted in a similar germline-loss phenotype, suggesting its role in quality control during embryonic development.
Using integrated information theory, researchers from the University of Tsukuba studied schools of Plecoglossus altivelis fish and found a discontinuity between three- and four-fish schools. The study revealed that leadership emerges in larger groups, improving understanding of collective behavior dynamics.
Researchers at CCNY provide new insights on nanoscale spin thermalization dynamics, discovering that groups of electron spins can facilitate communication between isolated nuclear spins. This breakthrough could enable devices using electron and nuclear spins for quantum information processing or sensing at the nanoscale.
A recent study by University of Zurich researchers has identified a key mechanism controlling brain development and cognitive function. The study found that a lipid metabolism enzyme, fatty acid synthase (FASN), regulates the lifelong activity of brain stem cells, leading to reduced division and learning deficits.
University of Utah engineer Massood Tabib-Azar has developed a portable, reusable test for COVID-19 that works with cellphones. The sensor uses just a drop of saliva and can produce results in a minute, and is designed to be reused multiple times by destroying the previous sample.
The Gemini North telescope has collected some of the highest resolution images of Jupiter ever obtained from the ground, complementing Hubble observations to reveal details about Jovian weather. The images show that lightning strikes and giant storm systems are formed in large convective cells over deep clouds of water ice and liquid.
A team of researchers at UPV's Nanophotonics Technology Center has discovered a new fundamental symmetry that allows the conservation of linear moment between dramatically different physical systems. This enables the design of pioneering optical, acoustic and elastic devices, including invisible omnidirectional materials.
Researchers have developed a new technique that uses 3D-printed aspherical microlenses to overcome the limitations of traditional microscope objectives. This allows for ultra-long-working-distance spectroscopy, enabling researchers to study single nanometre-sized light emitters without the need for bulky microscopes.