Researchers discovered that older mice made more of the two proteins in nasal cells than younger ones, explaining why older people are more susceptible to COVID-19. The study also found that sustentacular cells could potentially be infected by SARS-CoV-2, providing a route to infect the brain.
Research shows microalgae Arthrospira platensis (spirulina) closely matches pollen's essential amino acids and lipids required by honey bees. Spirulina also contains prebiotics supporting healthy gut bacteria growth.
Researchers found that participants synchronized their arm movements with those of the vocalizer, even with subtle and hard-to-detect movements. The study suggests that musculoskeletal tensioning affects speech, allowing for communication cues like excitement to be perceived through gesture-induced acoustics.
Researchers developed a novel approach to decontaminate single-cell RNA seq data, allowing for accurate quantification of cell-specific drug effects in pancreatic islets. The method revealed species-specific and cell-type-specific responses to drugs, including the induction of insulin production in alpha cells.
A new bat coronavirus, RmYN02, discovered in Yunnan province, China, is closely related to SARS-CoV-2. The virus contains natural insertions at the spike protein's junction, similar to SARS-CoV-2, suggesting it evolved naturally.
Researchers have uncovered the molecular mechanism of boswellic acid, a substance responsible for frankincense's anti-inflammatory effect. Frankincense reprograms the inflammatory enzyme 5-lipoxygenase into an anti-inflammatory enzyme.
Researchers used atom-probe tomography to study minerals from an asteroid over 4.5 billion years ago, discovering water precipitates that suggest the presence of sodium-rich fluids. These conditions are ideal for amino acid synthesis, potentially supporting microbial life formation as early as 4.5 billion years ago.
A diverse range of vaccine approaches is needed to address the global need for COVID-19 protection, with harmonized oversight bodies, shared criteria, and data sharing crucial for success. The ACTIV public-private partnership aims to scale up vaccine manufacturing capacity and distribution chains.
A recent brain imaging study suggests that the absence of a partner can strengthen the motivation to reunite, potentially driving the instinct to form lasting bonds. The research found unique clusters of cells in the brain associated with reunion and social distancing, shedding light on why social distancing is tough.
A new study published in Environmental Health Perspectives found a strong association between the loss of green space and an increase in cardiometabolic risk factors, including hypertension, obesity, and hyperglycaemia. The study analyzed data from over 6,000 adults living in an area south of Hyderabad undergoing urbanization.
Scientists at Temple University Health System discovered a novel mechanism between mitochondrial fission and endothelial cell inflammation. Salicylate reduces mitochondrial fragmentation, inflammation, and oxidative stress in the cardiovascular system.
Dr Ian Duncan has made groundbreaking research on how myelin is damaged in multiple sclerosis and how it may be repaired. His work focuses on transplanting myelinating cells to promote function in people with MS.
A study found that flowering strips benefit bumble bee colony reproduction by providing floral resources, but also increases the risk of a certain pathogen infection rate. However, the impact on foraging behavior and mortality was not significant.
Researchers have developed a novel magnetic nanotechnology that quickly and efficiently removes haze-forming proteins in white wine. The technology shows promise as a valuable and sustainable alternative to conventional bentonite fining treatments, potentially saving the wine industry millions annually.
Scientists used 3D models to study cancer cell DNA behavior, validating the use of these models for cancer research. The research team characterized the epigenetic fingerprint of human cancer organoids, showing that they closely resemble patient tumors and can be used to develop new oncology treatments.
A large study found that men have higher concentrations of ACE2 in their blood, which enables the coronavirus to infect healthy cells. This may explain why men with heart failure are more susceptible to COVID-19 than women. The study also found no link between RAAS inhibitors and increased ACE2 concentrations.
Researchers from the University of Tsukuba developed a novel high-yield method for producing the major birch pollen allergen Bet v 1 in plant leaves. The new system enables rapid and massive production of allergens, which can be used in clinical settings to desensitize patients to environmental allergies.
The study reveals that Asgard archaea, particularly the newly identified phylum Gerdarchaeota, are involved in degrading various substrates such as amino acids and ethanol. They also participate in aerobic respiration, converting substrates into acetyl-CoA.
Researchers analyzed volcanic samples from Santorini and Aegina to understand why they have different eruption styles. The study found that the islands' locations on the Aegean microplate led to varying lava mix recipes, resulting in calderas versus lava domes.
A study by Dr. Yuqin Zou and colleagues reveals that hierarchically nanostructured NiO-Co3O4 electrodes with plentiful interface defects exhibit excellent HMF oxidation activity and stability. The researchers demonstrate the positive role of cation vacancies in catalyzing the electro-oxidation process.
A new University of Stirling study aims to understand how easing of COVID-19 pandemic restrictions can be managed to protect emergency services. The project will investigate policy options for reopening pubs, nightclubs, and restaurants while minimizing infection risks.
The 'uplift of the Tibetan Plateau' concept is debunked due to contradictory paleoaltimetric estimates, isotopic bias, and re-dating of key sites. The region's complex topography was formed before the India-Eurasia collision, with uplift beginning in the Eocene.
The discovery of pebble-shaped teeth in the fossil of Cartorhynchus lenticarpus, an early ichthyosaur species, sheds light on how these animals adapted to their environments. The unusual rounded teeth, likely used for crushing shells, suggest that smaller ichthyosaurs like Cartorhynchus lived closer to shore and fed on invertebrates.
Researchers at the University of Huddersfield are using lullabies to spread vital healthcare messages, including COVID-19 precautions, among African women. The Life-Saving Lullabies project has received £129,795 funding and aims to create zero-cost awareness campaigns that could be replicated globally.
The new soft robotics, called LEAP, have a spring-powered spine that enables rapid switching between stable states, allowing for faster movement and more forceful grasping. This innovation outperforms previous soft robots by reaching speeds of up to three times faster on solid surfaces.
Researchers developed open-source software PCAlipids to analyze individual lipid molecules, highlighting the effects of temperature and cholesterol on their behavior. The study aims to better understand the mechanisms behind these interactions.
A study at Columbia University Mailman School of Public Health found a strong association between long-term exposure to segregated neighborhoods and decreased processing speed in midlife. The study analyzed data from over 1,500 black participants and found that high segregation was linked to poorer cognitive function.
A new study published in the Journal of the Association of Environmental and Resource Economists finds that European Union Emissions Trading Scheme improves power plant fuel efficiency, reducing annual carbon emissions by 1.5 to 2 percent in Germany.
Fruit flies sleep more when unable to fly, adapting to challenging situations. Sleep helps animals respond effectively, according to researchers at WashU Medicine.
A recent OSU study highlights the grange as a community-based organization with close ties to public health goals. The grange's physical buildings and similar missions make it an ideal partner for health initiatives, including blood drives, mental health awareness classes, and food programs.
The COVID Recession has disproportionately affected workers with disabilities, with a 20% decline in employment for those with disabilities compared to a 14% decline for those without disabilities. The FAIR program in Louisiana is helping formerly incarcerated individuals with disabilities access services and supports.
Researchers studied geckos' unique toe mechanism, which allows them to adjust and distribute weight on various surfaces. This adaptation enables agile locomotion and is crucial for designing effective robot feet and grippers.
Scientists at Newcastle University have developed a new method to grow crystals of organic soluble molecules from nanoscale droplets, allowing for rapid screening of hundreds of experiments in minutes. This breakthrough could transform the analysis of small molecules and accelerate the discovery of new pharmaceutical agents.
Researchers have identified a new type of antigen-presenting immune cell that plays a crucial role in the immune response to respiratory virus infections. This discovery could explain how convalescent plasma boosts immune responses and offers new therapeutic opportunities for treating viral infections.
Researchers at IST Austria have demonstrated a new detection technology called microwave quantum illumination that utilizes entangled microwave photons to detect objects in noisy thermal environments. The technology has potential applications for ultra-low power biomedical imaging and security scanners.
Size-selective fisheries can impair reproductive success in fish populations by reducing the availability of reproductively superior large individuals. This, in turn, affects population growth and resilience, as sexual selection cannot operate effectively without a sufficient pool of optimal mates.
A new guide from Michigan Medicine provides data-driven insights to help hospitals decide which operations can restart first. The guide analyzes seven years' worth of data from dozens of hospitals, showing that certain procedures require more resources, such as intensive care beds and ventilators.
Researchers from the University of Groningen developed an algorithm that links large-scale changes to molecular-level simulations, enabling the simulation of a full-sized mitochondrial lipid membrane. This breakthrough allows for whole-cell simulations at a molecular level.
Scientists discovered that collagen produces harmful radicals when stretched, but these are quickly scavenged by nearby aromatic residues. The study suggests that collagen has evolved as a radical sponge to combat damage and may hold promise for improving tissue repair and transplantation in sports medicine.
Researchers at George Mason University have collaborated with the World Bank to develop a web portal, MASH-Pandemics, which provides evidence-based decision-making tools for hospitals responding to the COVID-19 pandemic. The models aid in optimizing hospital operations and resource allocation during surge demand.
A new standard for machine learning in telecommunications networks has been approved, enabling faster data transmission rates of up to 20 Gbps and reducing latency to less than 5ms. This breakthrough is made possible by the application of deep learning techniques, allowing for complex pattern recognition and network load management.
Researchers at ITMO University have successfully created a new nanocomposite from gold and titanium oxide by using lasers to tune its structure and properties. The technique enables better control over the nanocomposite's formation and has potential applications in industries such as air purification and fuel cells.
Researchers at Penn State have successfully developed a novel plasma medicine technique that effectively targets and kills bacteria in liquid cultures without developing resistance. The process uses low-temperature plasma generated from atmospheric pressure or liquids, creating reactive particles with antibacterial effects.
Researchers at NTU Singapore have developed a green method to create chitin, using two forms of food waste - prawn shells and discarded fruit - and fermenting them. The new process is more sustainable than current approaches, reducing energy consumption and chemical by-products.
Researchers discover Foxg1's role in controlling brain electrical activity, shedding light on rare genetic diseases like Rett Syndrome and West Syndrome. Understanding this mechanism is crucial for developing future therapeutic interventions.
A Korean research team developed a new vaccine platform using RNA-based adjuvants for the MERS coronavirus. The platform was successfully tested on nonhuman primates with 100% protective efficacy. The researchers expect the platform to be applicable to COVID-19 vaccine development, which is urgently needed globally.
Researchers at the University of Bonn discovered that gamma-secretase, a protein shredder, indirectly regulates fat metabolism in brain cells. This process can lead to adiposis, disrupting cellular functions, while also having potential benefits against cancer by inhibiting tumor cell division.
Researchers have discovered that single molecular nanowires outperform bundles in transporting energy with minimal losses. Coherence, which enables delocalized energy movement across multiple molecules, is lost in bundled fibers due to strain, hindering efficient energy transfer.
A team of Michigan State University scientists developed a reliable model to study giant viruses, identifying key proteins that orchestrate infection and release their genome. The study revealed three environmental conditions that induce stargate opening, allowing researchers to mimic stages of infection with high frequency.
A Canadian study of global COVID-19 data found that temperature and latitude are not associated with the virus's spread, contrary to initial expectations. However, school closures, social distancing, and other public health measures have been shown to slow epidemic growth.
A new paper identifies urgent issues to consider, including potential animal-to-human transmission, food security concerns, and national security threats if military service dogs are infected. Stringent studies are needed to understand the risks posed by domestic animals as a possible source for human infection.
A review of pediatric COVID-19 imaging findings reveals unique characteristics, such as the halo sign and subpleural sparing. These features can help radiologists narrow the differential diagnosis, leading to optimal patient care.
Researchers discovered that herpes simplex virus (HSV1) targets the STING protein in brain cells to evade the immune response, promoting viral infection. This finding could lead to new antiviral treatments, particularly for immunocompromised patients with severe HSV1 brain infections.
Nathan Sleeter is directing a project to create classroom simulations on historical diplomacy events for secondary education. The simulations will include interactive tools and resources for instructors.
The development of an effective COVID-19 vaccine is critical to preventing repeated epidemics due to the human population's naivety to the virus. A judicious approach involves evaluating candidate vaccines in healthy adults while also using animal models, with parallel process development for efficient production scale-up.
Researchers at the University of Pittsburgh School of Medicine have made a groundbreaking discovery that could lead to a significant increase in long-term survival of transplanted organs. The study found that the innate immune system can specifically remember foreign cells, paving the way for new drugs that can prevent chronic rejection.
The article highlights how immigrant communities in the Bronx, NY are disproportionately affected by COVID-19. The authors advocate for a more equitable healthcare system to address these disparities.
A recent study published in Frontiers in Immunology found that pangolins lack two virus-sensing genes, which may help them tolerate the coronavirus. Understanding this evolutionary advantage could lead to new treatment options for COVID-19 in humans.
A two-week course of antiviral therapy with interferon beta-1b plus lopinavir-ritonavir and ribavirin has been found to be safe and more effective at reducing the duration of viral shedding than lopinavir-ritonavir alone in patients with mild to moderate COVID-19. The treatment combination also showed significant shortening of hospital...
The number of stroke evaluations at US hospitals has dropped by nearly 40% during the pandemic, suggesting many people are delaying medical care. This delay can lead to reduced access to life-saving treatments and increased risk of death and disability.