Researchers at Children's Hospital of Philadelphia analyzed seven patients with MIS-C-associated rashes and found several common types, including small-to-medium annular plaques on the chest and back, and purpura in the center. The study aims to help doctors and parents identify suspicious rashes and seek further examination.
A new study published in Hypertension Journal Report found that a structured exercise program improved artery health and function in middle-aged and older men with low-to-normal testosterone levels. The study showed no benefits from testosterone therapy on artery health.
A study by German Centre for Integrative Biodiversity Research (iDiv) found that plant species often respond to climate drivers months or even years later than previously assumed. The research analyzed 76 studies on 104 plant species and discovered that climate conditions during dormant seasons can have significant effects on plants.
A hormone called MOTS-c can help maintain healthy muscles in mice on high-fat diets by reducing myostatin levels. The study suggests that boosting mitochondrial function is also key to treating muscle-wasting conditions such as sarcopenia.
A study found that the HAND2 gene becomes less active in humans as labor nears, suggesting it may play a role in regulating gestation length. The gene evolved to be turned on in uterine linings of placental mammals during pregnancy.
A new study found adults with Down syndrome are roughly three times more likely to die from COVID-19 than the general population. The study's results have implications for preventive and clinical management of COVID-19 patients with Down syndrome, highlighting the need to prioritize individuals with this genetic condition for vaccination.
Researchers have identified a two-metre-long kangaroo painting in Western Australia's Kimberley region as Australia's oldest known in-situ painting, dated to 17,500-17,100 years ago. The discovery provides insight into the lives of ancient artists and the environment during the Last Ice Age.
Researchers at NASA and German Aerospace Center sent microbes to Earth's stratosphere, replicating Martian conditions, to test their endurance. The study found that some microorganisms, such as spores from the black mold fungus, could survive high UV radiation and desiccation during space travel.
Researchers found that most high-energy astrophysical neutrinos are born near quasars with massive black holes. This challenges previous theories suggesting only highest-energy neutrinos could be produced by these sources.
Researchers at EPFL successfully modeled ILC using a xenograft approach that simulates the tumor with high accuracy. The model reveals unique characteristics of ILC biology, including LOXL1's role in tumor progression.
A study predicts that increasing ice melt could lead to abrupt changes in the Atlantic Meridional Overturning Circulation (AMOC), potentially collapsing it even if freshwater influx remains below a critical threshold. The system's chaotic dynamics make predicting tipping points challenging.
Climate change affects soil microbial community diversity, structure, and activities. A new study found that warming enhances microbial network complexity and stability, supporting the central ecological belief that complexity begets stability.
A systematic review found that female patients treated by female physicians experience better outcomes, while those treated by male physicians face higher mortality rates. The study suggests that increasing gender diversity in the physician workforce and improving training on patient-centered communication can help combat disparities.
Scientists have developed a laser-driven soft X-ray source using an antiresonant gas-filled hollow core fibre, achieving a record-breaking 100 kHz-class repetition rate. This breakthrough technology offers a compact, high-flux SXR source suitable for various applications in fundamental and applied sciences.
A recent study led by University of Arkansas geologist Jill A. Marshall found that cold temperatures during North America's last ice age shaped landscapes well beyond the reach of glaciers, affecting areas from Oregon to Georgia and as far south as Texas and Arkansas. The research suggests past cold climates have had a significant impa...
A recent study reveals how bacteria develop tolerance to beta-lactam antibiotics, leading to persistent infections. The researchers identified a system that mitigates iron toxicity in tolerant bacteria, opening the door for new therapies that exploit oxidative damage and iron influx.
A new Stanford-led study investigates air pollution's effects at the single cell level and its impact on cardiovascular and immune systems in children. The analysis reveals that brief exposure to fine particulate matter can alter gene regulation, potentially leading to increased risk of disease later in life.
Climate change may cause geographical mismatches between crops and their pollinators, threatening crop yields. The study found potential declines in the distribution of some wild bees that pollinate tomatoes, particularly in the eastern United States.
Research finds elevated air pollution events, like wildfire smoke and inversions, impact indoor spaces. Indoor air quality is up to 30% of outdoor levels during inversions, while wildfires can increase pollution by 78%.
Research suggests that cognitive behavioral therapy (CBT) can help unemployed individuals find a new job or transition to full-time work within 16 weeks. The treatment also improves productivity and reduces negative beliefs associated with depression.
Research integrating genetics and archaeology reveals that diverse East Asians derive ancestry from a shared lineage that split over 40,000 years ago. This ancient lineage contributed to the development of modern languages, including Sino-Tibetan and Japonic families.
A new study finds that peer aggression occurs at higher rates between friends and friends-of-friends than between those not closely tied. This form of bullying is often driven by a desire for social status and can be particularly difficult to stem.
A team of researchers used a machine-learning approach to map the genetic and environmental connectivity of Aedes aegypti mosquitoes, a primary vector for diseases such as dengue fever and Zika. The study provides insights into the mosquito's adaptability to new landscapes and expanding range.
The study demonstrates MEK inhibitors as a promising targeted therapy for basal subtype bladder cancer, highlighting the importance of 3D cell culture drug screening. Established genomic and transcriptomic data are correlated with drug response to identify novel groups of tumors vulnerable to specific drugs.
Researchers from the GLOBE Institute at University of Copenhagen found that water may be present during planet formation, applicable to Earth, Venus, and Mars. The study suggests that planets with similar building blocks and temperature conditions as Earth may have oceans and continents.
Researchers found that an experimental treatment converted cells to generate insulin, reducing diabetic symptoms and increasing insulin cell mass. The treatment showed promise for regenerating insulin-producing capacity and restoring normal blood glucose balance.
Researchers at San Diego Zoo Global have successfully generated induced pluripotent stem cells from frozen fibroblast cell lines of northern and southern white rhinoceroses. This groundbreaking achievement marks the first step towards potentially bringing back this critically endangered species through gamete creation.
Scientists at Cornell University have successfully created a material structure that simultaneously exhibits superconductivity and the quantum Hall effect. This breakthrough could enable the development of more efficient electronics, such as data centers cooled to extremely low temperatures.
Scientists have developed a method to visualize and quantify alternative structures of RNA molecules, identifying a conserved structural switch in the SARS-CoV-2 virus. This technique has implications for understanding viral replication and potential targets for antiviral therapy.
Researchers identified three m6A modification patterns in HCC, each with distinct metabolic characteristics. These patterns were associated with differences in tumor stage, prognosis, and response to treatment. The study provides novel insights into potential prognostic markers and response to treatment in patients with HCC.
A new AI algorithm enabled a fully automated artificial pancreas system to achieve improved glucose control without manual input of meal or exercise information. This breakthrough could lead to more efficient and hassle-free diabetes management.
Researchers from INRS have developed a new approach for foldable and solid electrochromic devices using silver nanowires coated with compact gold shells. The device demonstrates high stability and flexibility in harsh environments, overcoming the limitations of traditional indium tin oxide-based devices.
The University of Houston Graduate College of Social Work research center has received $5 million in funding from Gilead Sciences, Inc. to continue its work combating the HIV/AIDS epidemic in the South. Led by Assistant Professor Samira Ali, the SUSTAIN Center focuses on improving frontline care and access for marginalized communities.
A University of Ottawa study found that using negative emojis in text messages produces a negative perception of the sender regardless of their true intent. This can lead to being labelled as a 'downer' and affects how warm or cold the receiver finds the message.
Researchers used medium-resolution satellite images to generate a burned area dataset for sub-Saharan Africa, resulting in significantly higher estimates of burned areas compared to coarse-resolution images. The study estimated fire carbon emissions at 1.44 PgC, substantially surpassing previous estimates.
A decade after childbirth, women with a history of hypertensive disorders of pregnancy may experience changes in the structure and function of their hearts, predisposing them to ischemic heart disease and heart failure. Early therapeutic interventions can help prevent long-term cardiac complications.
Tinnitus is a common hearing disorder affecting 7-8% of the population, causing irritability, depression, and even suicidal thoughts. Researchers review its pathophysiology, health impacts, and innovative engineering approaches to suppress its effects.
Researchers at Weill Cornell Medicine have discovered that pregnant women can transfer protective COVID-19 antibodies to their babies while in the womb. The study found that most babies born to mothers with COVID-19 antibodies had detectable antibodies, suggesting a potential shielding effect.
Researchers developed a framework to better predict extreme rainfall events in Mediterranean countries by analyzing weather data from 1979 to today. The study found strong relations between nine distinct atmospheric patterns and the location of extreme weather events.
Researchers at Massachusetts General Hospital discovered that activating nuclear IL-33 in chronic inflammation promotes abnormal cell growth and division, leading to cancer. Inhibiting IL-33's expression may help prevent cancers associated with inflammation.
Approximately 4% of the population naturally lack the activation receptor NKG2C due to a genetic variation. This absence is associated with an increased risk of developing severe COVID-19, particularly in intensive care unit patients.
Researchers successfully extracted DNA from marine shells, revealing insights into the genetics of animal shrinking. The technique sheds light on how animals like lemurs and lizards adapt to human hunting pressure.
A University of Queensland-led project combines old antibiotics with a new compound to revive their effectiveness against drug-resistant bacteria. The goal is to combat the growing threat of superbugs, particularly in low- and middle-income countries.
A recent study published in the Annals of Behavioral Medicine suggests that inconsistent sleep schedules in toddlers are associated with higher body mass index (BMI) percentiles. Researchers found that children from households living at or below poverty levels had more inconsistent sleep onset times, leading to higher BMI percentages.
Research reveals large galaxies steal molecular gas from smaller satellite galaxies, impacting star formation rates. The study provides new systematic evidence of gas loss through ram pressure stripping, leading to galaxy stagnation without gas acquisition.
A new study examines the effects of COVID-19 on low-income Black and Latino individuals with HIV, revealing successful indigenous coping strategies and gaps in healthcare access. Despite initial disruptions to care, overall engagement in HIV treatment remained relatively stable, highlighting the need for improved telehealth services an...
Engineers at the University of California, Riverside developed a flexible film that combines excellent electromagnetic shielding with ease of manufacture, promising for high-frequency communication technologies. The film, made from a polymer matrix filled with bundles of quasi-one-dimensional van der Waals materials, demonstrates excep...
Researchers from Skoltech have designed a software-based algorithm for synchronizing time across smartphones, achieving an accuracy of several microseconds. This method can be used to create a network of sensors and has potential applications in various fields, including photography and noise cancellation.
GraphIt, a state-of-the-art graph programming language, has been extended to run on graphics processing units (GPUs), enabling faster graph analysis. This advance accelerates graph algorithms, particularly those that benefit from parallelism, such as recommendation algorithms and internet search functions.
England's salt reduction programme achieved a 15% decline in average population-level salt intake from 2000 to 2011. The programme is projected to have prevented nearly 200,000 premature cardiovascular disease cases and £1.64 billion in healthcare cost savings by 2050.
An international collaboration has captured ribosomes translating messenger RNA from the maternally inherited mitochondrial genome, revealing a novel gating mechanism that prevents premature protein misfolding. This breakthrough uses cryo-electron microscopy to investigate protein folding processes at unprecedented resolution.
A study analyzing 100-year-old salmon scales found a 70% decline in wild sockeye salmon populations and diversity in the Skeena River. This decline has weakened the adaptive potential for salmon to survive climate change.
Tau oligomers form droplets within TIA1 droplets selectively, producing highly lethal effects on neurons. The study provides a tool to screen compounds that can inhibit tau oligomer formation, offering hope for Alzheimer's and frontotemporal dementia treatment.
A new study by Syracuse University researchers reveals that material hardship is linked to poor health, depression, sleep problems, and suicidal thoughts in young adults aged 24-32. The study found that struggling to meet basic needs increases the likelihood of reporting these negative health outcomes.
A recent survey study examined changes in abortion policies among US states from 2017 to 2020. The findings showed that state laws on abortion services have become increasingly complex, with some states expanding access to abortion and others imposing strict restrictions.
Scientists have imaged a rare bolide, an extremely bright meteoroid explosion, in Jupiter's upper atmosphere using the Ultraviolet Spectrograph on board the Juno spacecraft. The event was observed for just 17 milliseconds and had distinct spectral characteristics different from the planet's auroras.
The Kessler Foundation is conducting a two-year study on the role of hemarthroses in the development of osteoarthritis of the knee in military personnel. The team aims to explore regenerative processes to counter toxic effects of joint injury and prevent long-term damage.
The opioid and HIV epidemics in West Virginia are deeply interconnected, requiring a comprehensive approach to address both issues simultaneously. Stigma is a significant barrier to combating these epidemics, particularly in rural areas with limited resources.
This study introduces a new method using terrestrial laser scanning to monitor changes in leaf water content of tree communities. The technique allows for the measurement and monitoring of leaf water content with increased accuracy.
A new study published in Nature Communications found that high fructose diets can cause the immune system to become inflamed, leading to damage and increasing the risk of disease. The research also suggests a link between fructose consumption and obesity, type 2 diabetes, and non-alcoholic fatty liver disease.