The ASHP published two landmark reports articulating a futuristic vision for pharmacy practice, including expanded roles and optimized medication use. The reports outline opportunities for pharmacy leaders to advance patient-centered care and population health, and recommend adopting the HVPE framework and Pharmacy Forecast report.
The US and UK's large vaccine stockpiles are morally reprehensible, argue experts, as poor countries face years of vaccine scarcity. Rich nations should prioritize global access to COVID-19 vaccines to respect human rights and reduce the pandemic's spread.
A new study combines complexity science and social risk management to understand the impact of globalization, digitalization, and sustainabilization on societal coherence. The research finds that rapid shifts in public opinion and the emergence of populist movements can pose a threat to diversity and cohesion.
A new commission report calls for eye care to be included in mainstream health services and development policies to achieve Universal Health Coverage and the 2030 SDGs. Improving eye health can have immediate benefits for individuals and nations, including economic gains of $AUD 530 billion a year.
The study found that eight montane hotspots harbor 58% of fern species, with heightened diversity at elevations over 1000m. Ferns' rapid diversification is linked to tropical mountain ecosystems with stable climates.
Cytoglobin has been identified as a key player in delaying liver fibrosis progression in mice. The enhancement of CYGB on hepatic stellate cells or intravenous injection of recombinant CYGB suppresses liver damage and cirrhosis. This discovery holds promise for developing new anti-fibrotic therapy for human chronic liver diseases.
A team of researchers used stellar kinematics to study dark matter in ultra-faint dwarf galaxies, revealing a dense core and limited scattering. This challenges existing theories on self-interacting dark matter, suggesting that supernova explosions may be responsible for less dense distributions.
A team of researchers at Tokyo Tech has designed a flexible and free-standing terahertz sensor array that can image irregularly shaped objects. The camera patch sheet can be easily cut into smaller sensors for better coverage, showcasing its potential in industrial applications such as quality control operations.
A recent study published in the EMBO Journal has provided new insights into the formation of mitoribosomes, revealing a complex network of assembly factors that shield the sensitive ribosomal core. The researchers identified five key assembly factors that are conserved across different species, including humans.
ORNL's Amanzi-ATS model simulates groundwater flow in Arctic ecosystems, revealing the impact of thawing permafrost on stream temperatures. New cobalt and nickel superalloys remain crack-free and defect-resistant in extreme heat, enabling metal-based 3D printing applications.
Researchers used positron emission tomography (PET) imaging with 18F-fluoroestradiol to predict response to a novel treatment for ER-positive, HER2-negative metastatic breast cancer patients. The study found that higher baseline 18F-fluoroestradiol uptake was associated with longer progression-free survival.
Researchers studied cell interactions in a microscopic 'cell collider' and found that normal cells repel each other's protrusions, while cancer cells try to squeeze past each other. The study suggests new approaches for understanding cancer cell behavior and identifying molecular bases for these differences.
Scientists have developed a platinum-gold alloy catalyst that enables efficient hydrogen peroxide production from hydrogen and oxygen at room temperature. The new process achieves a selectivity of 95%, reducing the formation of unwanted water byproducts.
Researchers propose a new strategy to obtain size-controlled Eu3+-complex nanoparticles with self-assembly induced luminescence characteristics. The amphiphilic Eu3+-complex possessing carbazole derivative ligands can self-assemble into Eu-NPs with excellent water dispersibility and controllable particle size in aqueous solution.
Army researchers studied moral dilemmas involving autonomous machines, revealing that risk and social influence shape decision-making. The study contributes to the development of AI systems that reflect society's ethical standards, facilitating adoption by the Army and acceptance by the general public.
A new study analyzes the relationship between the Mongolian cyclone and the South Asian high, finding that their coupling accounts for 66% of seasonal rainfall anomalies in China. The research suggests that enhancing summer rainfall forecast skill in China can be achieved by analyzing these phenomena in the upper-level atmosphere.
Researchers found that delayed treatment improved surgical outcomes and reduced complications for facial bone injuries. The 'Critical Revascularization Period' allows for healing and formation of new blood vessels, improving oxygen supply and reducing morbidity.
A study by Hebrew University researchers found that natural disasters lead to a decrease in crime and an increase in charitable giving in directly affected areas. However, neighboring regions experienced a marked increase in philanthropy, driven by empathy and solidarity.
Researchers found strong seismic shaking deformed sediments and triggered mud avalanches, indicating extreme earthquakes preceded rockslide clusters. The study proposes seismic shaking can degrade rock slopes towards critical tipping point.
Researchers have identified a new signaling pathway, LIGHT/LTbR, that is specific to leukemic stem cells and can be targeted to eliminate them. Blocking this pathway has been shown to increase the survival of animals with leukemia.
A new study from USC provides a universal accounting method to measure organic carbon accumulation and cycling in the ocean. The framework reconciles competing theories and explains how oceans regulate organic carbon across time.
A new Geisel-led study found substantial regional variation in the intensity of fracture-associated drug (FAD) use among long-term care facility residents, with areas experiencing higher FAD use having higher hip fracture rates. The study analyzed Medicare data and prescription records, revealing a 12% difference in FAD prescribing ran...
Research from the University of Copenhagen finds that prolonged exercise increases GDF15 production, suggesting a physiological stress signal. This natural release of GDF15 may induce satiety and reduce appetite, making it a promising area of study for anti-obesity drugs.
A new study reports that activated B. infantis EVC001 improves health outcomes in preterm infants by reducing enteric inflammation, diaper rash, and antibiotic use. The probiotic also enhances gut microbial composition and reduces pathogenic bacteria, leading to improved clinical outcomes.
A team of scientists led by the University of Göttingen has discovered a connection between a specific gene and plant resistance to pathogens. The study found that plants lacking this gene accumulate active acids, but show increased resistance - at the cost of reduced growth.
A new method, Coherence Tomography with Extreme Ultraviolet Light (XCT), enables non-invasive observation and analysis of tiny structures in semiconductors. The technique uses broadband XUV radiation to generate coherent light with nanometer precision.
Researchers analyzed 751 pediatric patients treated for solid tumors and found germline genomic sequencing details for inherited gene mutations. This information can help guide treatment, family screening, and prevent future cancers.
French researchers explored mesophotic corals' distribution and adaptation in French Polynesian waters, from surface to 120m depth. They found that certain filamentous algae play a crucial role in coral survival at depth by capturing shorter light wavelengths.
A research project led by Albert Banal-Estanol and Massimo Motta aims to analyze the factors that determine a company's market power and their impact on consumers. The study also explores regulatory interventions in areas of consumer protection, product safety, and digital markets.
Researchers found a group of genes on chromosome 12 that reduces the risk of developing severe COVID-19 by around 20%, inherited from Neanderthals. These genes code for enzymes that help destroy viral genomes, and the Neanderthal variant is more efficient, providing protection against severe COVID-19.
Scientists at the University of Würzburg have successfully applied optogenetic methods in tobacco plants, enabling non-invasive manipulation of intact plants or selected cells by light. This breakthrough allows researchers to study molecular mechanisms of plant growth processes in detail.
A new study found that lesbian, gay, and bisexual (LGB) individuals are more likely to experience mental health conditions and report alcohol and drug misuse than heterosexuals. The research analyzed data from the Adult Psychiatric Morbidity Surveys and found no improvement in disparities between 2007 and 2014.
A Swedish health survey has found that young people's perceptions of their socioeconomic status can have a significant impact on their health. The study, published in Children & Society, explores how the survey questions shape young people's views on life and identity.
A new study reveals that antibody effector functions are crucial for effectively treating COVID-19 infections, but dispensable when preventing infection. Researchers found that optimized effector functions can boost the potency of next-generation COVID-19 antibody drugs, while removing them may hinder treatment effectiveness.
A study examines nearly 1,000 Instagram posts and finds that most gorilla trekking tourists were close to the animals without face masks on, risking disease transmission. Strengthening tour regulations is crucial to protect these already imperiled great apes from further threats.
The UK Centre for Greening Finance and Investment will provide environmentally sustainable decision-making tools for lenders, investors, and insurers. The centre aims to shift money away from harmful activities and towards renewable power and sustainable agriculture.
This study evaluated the setting behavior of two bioceramic materials under different environmental conditions. The results showed that MTA Angelus exhibited significantly higher hardness values compared to NeoMTA Plus, regardless of wet or dry conditions.
A novel approach by a West Virginia University researcher aims to gauge restoration success in wetlands. By measuring shrubs at ground level, he advances the criteria for assessing long-term restoration potential, providing a better indication of success.
The article discusses the relationship between DNA repair pathways and cancer cells, highlighting five critical pathways and their impact on cancer evolution. The review suggests potential clinical interventions to address pathway damage, offering new insights into cancer treatment.
The study used thermal proteome profiling to analyze SARS-CoV-2 infection's impact on human proteins. Hundreds of cellular proteins showed changes in abundance and thermal stability, suggesting the virus hijacks them for replication.
A genetic study of Lewy body dementia suggests that the disease is caused by a spectrum of problems seen in both Alzheimer's and Parkinson's diseases. Five genes have been identified as critical to the development of Lewy body dementia, with variations in these genes also linked to increased risk of Alzheimer's and Parkinson's diseases.
A new radioactive bone cement has been developed as an alternative to conventional radiation therapy for treating spinal tumors. The cement can be injected into the spine to directly irradiate tumors without harming the spinal cord, promising to eliminate side effects and limit treatment options.
Researchers found significant eye abnormalities in severe COVID-19 patients using MRI scans, suggesting the need for routine eye screening. The study also recommends dedicated exploration of eyes with high-resolution MRI, fundoscopy, and optical coherence tomography to detect nodules and monitor their impact.
A study found that maternal cardiovascular health during pregnancy is associated with the later cardiovascular health of their offspring in adolescence. The research examined various factors such as body mass index, blood pressure, and cholesterol levels.
A study published by the American Psychological Association found that response speed is an important cue on which people base their sincerity inferences. Participants rated delayed responses as less sincere than immediate ones, regardless of the question's seriousness.
CRIRES+ is a high-resolution infrared spectrograph designed to study planets outside our solar system. It detects super-Earths, planets in the habitable zone around their star, and analyzes their atmospheres during transits.
Researchers from the University of Tsukuba found that ocean acidification favors degraded turf algal systems over corals and other algae due to feedback loops. This ecological shift makes it difficult to reverse and has significant implications for coastal ecosystem services.
An international team has developed a cassava variety with high-level resistance to two devastating diseases and higher levels of iron and zinc. The research builds on previous work demonstrating that increasing mineral content in cassava storage roots is possible using RNAi-mediated technology.
A phase III randomized study found that lenvatinib plus pembrolizumab significantly prolonged survival in patients with advanced kidney cancer. Treatment combinations showed improved progression-free and overall survival rates compared to sunitinib.
A recent study from Cornell University-led research highlights the risk of overvaluing prototypical leaders and undervaluing management skills. Participants preferred to hire a CEO with strong leadership qualities over those with more managerial expertise, despite the organization's need for management skills.
In a new study, Northwestern University researchers found that air quality and public health benefits of electric vehicles in China depend on the type of transport electrified and the composition of the electric grid. Electrifying 40% of heavy-duty vehicles improved air quality while reducing greenhouse gas emissions.
The study found that schools with armed guards had lower average injury rates and fewer severe injuries compared to those without armed guards. Armed guard presence was also associated with a decrease in the use of firearms during school shootings.
Children born through fertility treatment have different growth patterns than naturally-conceived children, but by age 17, they are similar in height, weight, and BMI. ART children grew more quickly in their first 18 months and showed a similar growth pattern as subfertile parents' children.
The UK must decommission around 300 and 1600 early-model offshore wind turbines by 2025 and 2030, respectively. Research reveals that the remaining years before these original turbines' end of life can be proactively used to prevent safety lapses and huge costs.
A new study found COVID-19 infection rates among pregnant women to be 70% higher than in similar-aged adults in Washington state. Pregnant patients from communities of color experienced a twofold to fourfold higher prevalence of infections compared to the general population.
Researchers at Regenstrief Institute have developed SymTrak-8, a short questionnaire to track symptoms in older adults and assist healthcare providers in assessing treatment effectiveness. The tool provides a more complete picture of overall wellbeing and symptom burden, enabling clinicians to make informed decisions.
A new survey found that 52% of UK adults thought the government was doing a good job controlling COVID-19, despite lower levels of trust in its honesty and transparency. The study suggests that targeted community engagement measures can help maintain public support for control guidelines.
Scientists have developed a highly sensitive antibody test that can detect all known human coronaviruses, including new SARS-CoV-2 variants. The test uses 29 immune signatures specific to SARS-CoV-2 and has been validated with a high specificity and sensitivity rate.
Researchers discovered that tumors with low glycolysis levels respond better to CTLA-4 blockade, which destabilizes and reprograms regulatory T cells. This approach aims to personalize anti-CTLA-4 therapy for patients with these tumors.
Researchers from Chung-Ang University have successfully produced anion-exchanged porous SnTe nanosheets with ultra-low thermal conductivity and high-performance thermoelectrics. This breakthrough has significant implications for energy generation, refrigeration, transportation, and biomedical devices.