A new study by NYUAD researchers demonstrates a small molecule protein mimetic can reactivate the tumor suppressor protein p53, which is often mutated and deactivated in cancer. The treatment effectively shrinks tumors and prolongs survival with no noticeable toxicity to healthy tissue.
Researchers reviewed approaches to multi-material multi-photon micro/nano-printing, enabling targeted structures with diverse material properties. Automated systems are rapidly developing for combining multiple primary materials within a single machine tool.
A recent study using REST-meta-PD analyzed brain activity data from 15 PD patient studies, finding that up to 80% of voxels declared significant may not be replicable across datasets. The researchers propose a normative modelling method to improve reproducibility and generalizability.
Researchers from USTC realized the first on-chip valley-dependent quantum interference in silicon photonic crystals using harpoon-shaped beam splitters. The study demonstrates a novel method for topological photonics and its potential applications in complex quantum information processing.
A recent study found that coral reefs in the South China Sea adjust their trophic patterns in response to environmental conditions. By analyzing zooxanthellae density, nutrient levels, and light intensity, researchers discovered that corals can shift from autotrophic to heterotrophic modes of nutrition, enhancing their adaptability to ...
Research reveals that saturated fatty acids play a key role in forming memories, particularly in the amygdala region of the brain. The study found that levels of myristic acid, found in coconut oil and butter, increased significantly as new memories were formed.
Researchers developed sensitive SERS substrates via femtosecond laser processing for real-time sensing in biomedicine and microfluidic chips. Attomolar detection capabilities were achieved through synergistic enhancement effects, opening up new avenues for monitoring and sensing applications.
A recent study found that China's annual mean surface wind speed stopped weakening around 2014 and started strengthening, but stilling persists in certain regions. The reversal was driven by regional and seasonal variations.
The 70th Lindau Nobel Laureate Meeting has opened with a record number of participants, featuring discussions on topical issues such as future pandemics, gene editing, and climate change. The meeting aims to foster dialogue among scientists from around the world and promote sustainable scientific conduct.
Researchers propose a triple-cycle heat treatment system to improve the microstructure and performance of 3D printed titanium-molybdenum alloy human implants, achieving better biocompatibility and mechanical properties matching human bones. This method enables more widespread use of 3D printed implants in the biomedical field.
A new study from Uppsala University reveals that males play a crucial role in maintaining genetic health by eliminating harmful mutations. The research found that selective pressure on males leads to the purging of deleterious mutations, resulting in healthier genes and increased reproductive capacity.
The research team established a single lysosome mass spectrometry platform to analyze the metabolic heterogeneity of various lysosome types in cell aging. They found that each type of lysosomal subset exhibited distinct metabonomics changes, indicating lysosome type specificity in cellular aging.
Researchers at Columbia University School of Engineering and Applied Science have developed a computer vision technique that enables machines to predict human behavior with higher accuracy. The algorithm leverages higher-level associations between people, animals, and objects to make more intuitive predictions about future actions, ope...
A new study reveals that 16 out of 146 health-related APPGs in the UK received over £1 million in payments from pharmaceutical companies between 2012-2018. The researchers argue that a lack of transparency highlights potential conflicts of interests towards public policy, despite no evidence of wrongdoing.
A recent study identified 363 marine invertebrate RNA viruses from 58 samples, revealing high genetic diversity and elasticity. The findings suggest possible virus transmission across different ocean areas and host species, shedding light on the origin of hantaviruses.