Researchers at Keck School of Medicine and Caltech demonstrate a new way to produce highly detailed images of the human brain using functional photoacoustic computerized tomography (fPACT). This technology has the potential to be less expensive, more portable, and accessible to patients with implants.
Despite a 19% increase in global spending on science and a 13.7% rise in scientists, significant disparities remain, with only two countries accounting for nearly 63% of the investment. The report highlights the need for more diverse and inclusive science policy, emphasizing the importance of women's participation in research.
A recent US study estimated the incidence of multisystem inflammatory syndrome in children among people with SARS-CoV-2 infection. The study found a significant association between MIS-C and severe COVID-19, highlighting the need for vigilance and prompt medical attention.
Plants use metabolites, chemical signals, and dual receptor recognition to distinguish beneficial microbes from pathogens. A plant cell follows a flowchart to determine the response needed based on microbe type and lifestyle.
An international research project, funded by DFG, explores how governments, health institutions, and media communicate about COVID-19, analyzing its effects on the population. The study aims to identify effective risk and crisis communication strategies for better public understanding of pandemic risks.
A study categorizes existing solutions for combating maritime litter, revealing a need for more developed technologies and integrated approaches. The researchers recommend defining standards for each solution to encourage further development and create a sustainable approach.
Researchers from Skoltech conducted experiments measuring gas permeability under various conditions for ice-containing sediments mimicking permafrost. The study showed high probability of increasing permeability coupled with dissociation of gas hydrates in permafrost, leading to methane emissions into the atmosphere.
Hebrew University archaeologists found a rare 7,000-year-old seal impression with geometric stamps, marking shipments or silos. The discovery provides early evidence of commercial activity and long-distance trade in the Middle East.
A KIT research team developed a new statistical method to improve global forecasts, enabling more accurate seasonal meteorological forecasts on the regional level. This can help mitigate local consequences of climate change, such as droughts and floods, by providing early warning of wet or dry periods.
Researchers found sequence changes in the beta myosin protein that explain the difference in contraction velocity between small and large mammals, with human and rat proteins differing at nine key sites. The study suggests these changes enabled slower heart rates in larger animals as they evolved from smaller species.
A study by Tanja Stratmann and colleagues found that sponges attached to manganese nodules provide a habitat for numerous animal species, including small worms, crabs, and clams. Removal of the nodules would disrupt this ecosystem, leading to a significant reduction in animal diversity.
The eleventh edition of the Art of Neuroscience competition has been won by Yas Crawford for her artwork 'Cognition IX', which explores neurological interoception in Myalgic Encephalomyelitis patients. The winner was chosen from over 293 entries and received praise for its perfectly composed image, full of movement and dynamic flow.
A massive rock and ice avalanche in February 2021 killed over 200 people in Uttarakhand, India. The disaster was exacerbated by exceptional avalanche height, rock-to-ice ratio, and downstream hydroelectric infrastructure, underscoring the need for sustainable planning.
A new study challenges the notion that widespread Indigenous population decline led to significant forest regrowth in tropical regions. Instead, it found that dense and highland forests were less likely to show signs of afforestation following Spanish contact.
Researchers at TU Dresden and TU Munich developed a novel method to engineer the energy gap in organic semiconductors by blending materials with varying molecular shapes. This approach enables continuous tunability of the energy gap, paving the way for efficient optoelectronic devices.
Researchers have found that restoration action is at risk of failure if it doesn't consider the social and political dimensions of the effort. Key findings include a successful kelp restoration project centered on indigenous worldviews, and a lake restoration project whose main beneficiaries were well-heeled urban residents.
Researchers at KAUST developed a new molecular coating that significantly enhances the performance of organic photovoltaic cells, outperforming current materials like PEDOT:PSS. The coating increases efficiency by reducing electrical resistance, improving hole transport, and allowing more light to pass through.
A large-scale brain epigenetics study has identified 84 new genes linked to dementia, providing new insights into the disease. The study found that epigenetic changes in the brain can be consistently distinguished from those without the disease, with over 70% accuracy.
Researchers found that COVID-19 virus can enter and replicate in human kidney cells, but does not typically cause cell death. However, infected cells with pre-existing injury are more susceptible to additional damage.
Researchers at Michigan State University have developed a new dataset to diagnose broadband availability, revealing significant gaps in urban, suburban, and rural areas. The tool aims to help policymakers allocate resources efficiently to improve local conditions.
A new study on Petermann Glacier found that the way under-ice landscape is represented in models can significantly impact future sea-level rise predictions. The researchers discovered that a warmer ocean could trigger the break-up of the glacier, leading to increased mass loss from Earth's polar ice sheets.
A new study using near-infrared (NIR) spectrum cameras has shown that these small, mobile cameras can help detect more snakes and could lead to an automated python tracker. By utilizing NIR cameras, pythons can be detected 20% farther away than with visible cameras.
A Southern Cross University study reveals global coral reef ecosystem calcification is declining at a rate of 4.3% yr-1, with consequences for ecosystem survival. The decline may be linked to stress events and reduced coral cover, potentially impacting food and habitat production.
Researchers discovered a molecular mechanism that alters immune response to infection in Gouin children, but not in Fulani children. The study's findings could lead to better malarial therapeutic interventions and vaccine responsiveness in populations.
Disabled researchers face barriers in academia due to inaccessible workplaces and normative departmental cultures. Collaborative research with mixed groups can help attract, support, and retain people with disabilities.
A novel tau protein conformation, cis P-tau, is a toxic early driver of Alzheimer's disease and related dementias. Silencing of this protein through immunotherapy has been shown to prevent disease pathology and memory loss in preclinical models.
Researchers developed AstroPath, a platform combining astronomy and pathology to analyze tumor microenvironments. It predicts response to anti-PD-1 therapy in melanoma patients, providing new insights into cancer treatment options.
Researchers at University of Texas M. D. Anderson Cancer Center found that combination ibrutinib and venetoclax provided lasting disease remission in patients with newly diagnosed chronic lymphocytic leukemia (CLL), with a three-year overall survival rate of 96%
The Brainlife.io platform uses cloud technologies to democratize neuroscience research, allowing scientists to process, visualize, and manage large amounts of data. The platform provides a suite of web services to support reproducible research, with over 1,600 scientists from around the world accessing it thus far.
A joint research team from POSTECH and KIMS developed a deep learning-based refocusing method to detect and improve SEM images without human oversight. The technology demonstrated improved image quality on blind settings, moving closer to commercializing AI-based material analysis equipment.
Researchers have identified a promising strategy for combating antibiotic-resistant bacterial infections by targeting the production of hydrogen sulfide. The approach, which inhibits the enzyme cystathionine gamma-lyase, enhances the deadly effects of antimicrobials on drug-resistant pathogens.
A new study suggests that pointed shoes, popular in medieval Britain, led to a sharp increase in bunions, particularly among the wealthy and clergy. The researchers found that those buried in richer sites had a higher prevalence of hallux valgus, highlighting the fashion trend's significant impact on foot health.
Researchers found that middle-aged men with cerebral palsy are up to 5.6 times more likely to suffer fractures than men without the disorder. The study also revealed that critical periods of bone health vary across the lifespan for individuals with cerebral palsy, particularly affecting females and males at different times.
Researchers discovered the glasswing butterfly's unique wing structure, creating transparency through a lower density of scale cells and nanostructures. The findings also revealed an anti-glare coating made of waxy hydrocarbon nanopillars, making butterflies nearly invisible to predators.
Researchers mapped misfolded tau proteins' brain journey, finding they resist spread in certain areas. This discovery could lead to new therapies targeting specific brain regions.
Scientists have successfully transferred and recovered quantum coherence from photons scattered in free-space for the first time, paving the way for new applications in quantum communication, imaging, and sensing. The novel technique uses custom hardware to maintain coherence even after scattering from a diffuse surface.
Researchers found that mutations in cardiac myosin-binding protein C (cMyBP-C) cause HCM through unknown mechanisms, altering protein integrity or mechanical properties. This knowledge is crucial for clinical follow-up and treatment of patients and their families.
Researchers developed Seq-Scope technology to visualize all gene expression from a tissue sample, offering ultra-high-resolution imaging. The method, using high-throughput sequencing and barcode-based spatial coordinates, enables diagnosis of diseases at the microscopic scale.
The LMO1 gene codes for a protein that regulates RNA production and is implicated in cancer formation. Researchers found that overexpression of LMO1 is associated with poor patient outcomes in different cancers. Further study of LMO1 may lead to targeted therapies for various types of cancer.
Using a computer-aided, multi-material 3D-printing method, researchers have created custom healthcare devices with tailored shapes and functions to enhance patient wellbeing. The technique offers a solution for mass-produced medical devices by providing bespoke designs that can improve comfort and durability.
A study found that frequent cell phone use while driving is associated with other risky driving practices in young adults, including impulsivity and sensation seeking. The study suggests that targeting all risky behaviors rather than just cell phone use may be more effective in preventing crashes.
Researchers at University of Freiburg discover how vanadium-dependent nitrogenase binds two CO molecules simultaneously, enabling reductive process for industrial applications. This breakthrough sheds new light on the mechanistic principles behind nitrogenase's ability to reduce toxic gas carbon monoxide.
Researchers discovered that blocking bacterial H2S biogenesis strengthens antibiotics by inhibiting persister formation and biofilm growth, offering a novel alternative to traditional antibiotic discovery. The study suggests using small molecule potentiators to enhance the effect of major classes of clinically important antibiotics.
Researchers used a novel statistical model to estimate new HIV infections among adult MSM in England between 2009 and 2018. The results suggest that testing and treatment strategies have been effective in reducing new infections, with a significant decrease in the number of new infections from 2,770 in 2013 to 854 in 2018.
A recent study from the University of Notre Dame found that disagreeable married men who do not contribute equally to household chores often have higher salaries due to increased focus on their careers. This phenomenon suggests that imbalanced social exchanges at home, particularly with spouses, play a crucial role in determining indiv...
The study reveals COVID-19 can cause inflammation in the auditory and vestibular pathways, worsening existing conditions like tinnitus. Pandemic-related stress and anxiety also increase the severity of tinnitus symptoms in individuals already affected.
Researchers from Cornell University and Samsung create a first-of-its-kind metalens that can focus light using voltage instead of mechanically moving its components. The innovation allows for an ultrathin, electrically tunable lens with continuous zoom capabilities.
Researchers have discovered a highly selective phage activation mechanism based on signal molecules in bacterial ecosystems. The study reveals that a specific bacterium produces a signal molecule that triggers the conversion of a latent phage into an active parasite, offering new possibilities for phage therapies and biotechnology.
Researchers at the University of Bradford say naked mole rats' long lifespan and resistance to cancer could lead to new treatments for degenerative diseases like cancer and dementia. The animals' unique DNA repair mechanism may provide insights into preventing these conditions, with potential applications in humans.
A new study reports that Elovanoids, a bioactive compound, block the virus that causes COVID-19 from entering cells and protect lung tissue. The researchers found that Elovanoids also triggered the production of protective proteins that counteract lung damage.
A team of Monash University scientists has discovered a new process based on phosphonium salts to produce green ammonia from renewable energy. The process represents a major contribution towards the development of a sustainable fuel for the future, with potential applications in fertiliser production and as an energy carrier.
Researchers discover that cytosolic dsDNA from mitochondria can cause cell death and neurodegeneration in PD patients. A new approach using DNAse II may help counteract this effect, potentially leading to a breakthrough in treating Parkinson's Disease.
A new study from Lawrence Berkeley National Laboratory uses a hydraulic model to quantify the impact of climate change on flooding in Houston, Texas during Hurricane Harvey. The research reveals that 14% to 15% of the cost of flooding was due to climate change.
Researchers from uOttawa propose a new optical element called spaceplate, which simulates light spreading in a small device, enabling the miniaturization of optical systems. This technology has potential applications in fields like healthcare, where thin cameras or endoscopes could be used to visualize internal organs.
The American Medical Association has awarded Penn State College of Medicine $1.8 million to develop residency education programs that prepare physicians for the complexities of modern healthcare. The project aims to equip residents with health systems science knowledge and skills to deliver high-quality patient care.
UC Riverside researchers have decoded the genome of a benign infection, potentially sending medicine into citrus trees. The discovery could harness its unique properties to deliver antibacterial and antiviral agents into plants' vascular systems.
A study of 700 children found that persistent childhood insomnia symptoms were associated with a higher risk of developing internalizing disorders, including depressive disorders and anxiety disorders. The researchers suggest that early interventions may be necessary to prevent future mental health problems.
A study reveals that black holes have an unexpected effect on galaxy evolution, influencing the formation of stars in satellite galaxies at vast distances. The research found a clear modulation of star formation rates depending on a galaxy's orientation with respect to its central black hole.
Researchers analyzed brain scans of 193 COVID-19 patients, finding a link between brain imaging and the virus's presence in cerebrospinal fluid. The study suggests hyperintense lesions and leptomeningeal enhancement are indicative of inflammation rather than infection.
Researchers found that normal breathing indoors without a mask can transport virus-laden saliva droplets up to 7.2 feet in just 90 seconds. Masks significantly restrict this movement, reducing the distance to less than 6 feet after two minutes.