Patients with REM sleep behavior disorder show signs of low blood flow and cognitive decline, suggesting a link between disrupted sleep and Parkinson's symptoms. The study aims to investigate the relationship between reduced blood flow and Parkinson's disease progression.
Researchers from South Ural State University and the Russian Academy of Sciences have synthesized six new acetylthioglycoside derivatives with potential anti-cancer effects. The compounds are based on a dithiolothionic cycle, which releases hydrogen sulfide, carbon monoxide, and nitric oxide.
Scientists investigate 'bite' defects in armchair and zigzag graphene nanoribbons, finding they can disrupt electronic transport but also yield spin-polarized currents. The study aims to minimize the detrimental effects of these defects on charge transport for next-generation nanotechnologies.
A new study suggests that exempting asthma medications from the deductible in high-deductible health plans may reduce medication use and exacerbations in children, but not adults. The research found small decreases in annual fills for some controller medications among children switching to HDHPs.
Researchers discovered that semi-aquatic anoles use a bubble to re-oxygenate the air they exhale, allowing them to stay underwater for extended periods. The lizards' hydrophobic skin facilitates this process, which is essential for their survival in aquatic habitats.
Researchers at Ruhr-Universität Bochum discovered two new attacks that break PDF certification signatures, enabling attackers to implant malicious code and insert fake content. The team tested 26 PDF applications, with 24 of them vulnerable to at least one attack.
A new study reveals that coal fly ash makes up a significant portion of particulate organic carbon carried by the Yangtze River in China. The study found that human activities, such as coal burning, have an outsized impact on river sediment, comparable to natural processes.
A recent study assesses the invasiveness of European and native plant species using three dimensions: local abundance, geographic extent, and habitat breadth. High values in these variables characterize successful invaders, with early introduction to Europe and rapid growth contributing to their success.
Researchers at the University of Oxford and their international team have discovered how SARS-CoV-2 RNA interacts with host cells, paving the way for new therapeutic strategies. The study found that SARS-CoV-2 hijacks more than 100 cellular proteins to replicate, providing a potential target for antiviral treatments.
A new study aims to identify diabetic donors whose corneas are suitable for transplant surgery, a crucial step in addressing growing demand for the procedure. The Diabetes Endothelial Keratoplasty Study will explore the impact of donor and recipient diabetes on outcomes and inform eye-banking and surgical practices.
A two-year study found that testosterone therapy normalised testosterone levels, reduced NAFLD, and suppressed symptoms of hypogonadism in obese men. Testosterone therapy may help obese men with functional hypogonadism and type-2 diabetes reduce the prevalence of non-alcoholic fatty liver disease.
A University of Houston research team creates a unique class of luminescent materials called phosphors that absorb violet LED's single-color emission and convert the light to cover the majority of the visible spectrum. The new LED bulb emits less blue light, reducing health concerns associated with overexposure.
MIT researchers have designed a sharp-tipped robot finger with tactile sensing to identify buried objects in granular material. The Digger Finger successfully sensed the shapes of submerged items and can penetrate sand and rice, with potential applications for finding buried cables or disarming bombs.
Researchers found that direct compensation for posting written reviews increases positive emotion, but may lead to overly glowing reviews that don't accurately reflect the experience. In experiments, incentives increased review positivity by 55%, but had unforeseen negative consequences for consumers.
Scientists have developed a way to engineer materials at the atomic level using a dry transfer technique. The method uses anthracene as a sacrificial material to precisely position carbon nanotubes, resulting in bright photoluminescence up to 5,000 times brighter than the original molecule.
Researchers found strong antiresonance in orthoferrite materials when placed at an odd angle under high magnetic fields. This unique state allows for ultrastrong interactions between magnons, which could lead to suppressed fluctuation noise and increased sensitivity in quantum sensing applications.
A new AI algorithm developed by TUM and Imperial College London can detect pneumonia in pediatric x-ray images while maintaining patient privacy. The algorithm uses federated learning, secure aggregation, and differential privacy to keep data onsite and prevent individual identification.
The National Science Foundation has renewed funding for the Materials Innovation Platform at Penn State's Materials Research Institute, enabling the development of new ultra-thin materials with unique quantum properties. The facility will advance 2D materials research across the US, supporting over 100 scientists nationwide.
Researchers at Texas A&M University have developed a method to compare the performance of different wind turbine designs, using machine learning and social science analysis. The study found that this technique can provide a robust and accurate way to determine the merit of competing technologies.
A small case series found that vaccination was not linked to worsening symptoms or reduced quality of life in patients with persistent COVID-19 symptoms. The study included 163 patients who received one dose of either Pfizer-BioNTech or Oxford-AstraZeneca vaccine.
A team of researchers from the University of Notre Dame developed a simulation model to better understand cosmic ray transport characteristics and improve detection techniques.
Since 1949, China has made notable progress in reducing maternal mortality and improving child survival rates, with significant reductions in death ratios from 1500 to 17.8 cases per 100,000 births and infant deaths from 200 to 5.6 cases per 1,000 births.
New study questions precession in the Milky Way's warp, suggesting it could disappear or become slower over time. Researchers used Gaia Mission data to analyze stars' positions and velocities.
Researchers analyzed PCR samples from over 25,000 COVID-19 cases to estimate infectiousness. Viral loads were found to be lowest in young children and increased with age. The study provides new insights into the B.1.1.7 variant and highlights individual differences in infectiousness.
A recent study by Desert Research Institute found that cold wildfire smoke can make soil surfaces hydrophobic, leading to severe water repellency and increased erosion. The research used sand samples treated with both hot and cold smoke, showing similar results in terms of water absorption time.
A study examining COVID-19 severity found associations between circulating sex hormones and disease outcomes in patients, highlighting the need for further research on hormonal factors. The investigation, published in JAMA Network Open, suggests that hormonal imbalances may contribute to varying levels of disease severity.
Researchers have discovered that tabernanthalog (TBG) rapidly corrects stress-induced behavioral deficits and promotes neuronal regrowth in mouse brains. TBG lacks toxic and hallucinogenic effects of ibogaine, making it a promising potential treatment for mental health conditions.
A study published in Archives of Rehabilitation Research and Clinical Translation found that prism adaptation treatment improves functional and cognitive independence scores for stroke survivors with spatial neglect. The treatment, which involves wearing goggles with optical prisms to shift motor movements, results in higher scores on ...
A study of 182 undergraduate students found that pandemic-related changes affected motivation levels variably, with some students becoming more motivated while others remained unchanged or became less motivated. Demographic factors such as socioeconomic status and first-generation student status did not significantly impact the findings.
Researchers at the University of Jyväskylä have demonstrated a new method to make graphene ultrastiff using optical forging, increasing its stiffness by several orders of magnitude. The technique, which involves irradiating defects in the graphene lattice, opens up new application areas for this wonder material.
Researchers from La Jolla Institute for Immunology have found that human T cells can target more than 1,400 sites on the SARS-CoV-2 virus, revealing a broad and diverse immune response. This analysis can help monitor effective responses to COVID-19 vaccines and track variations in T cell responses.
Researchers developed a mathematical model SSSAFE to predict landslides by analyzing slope stability over time. The model successfully predicted the 2017 Xinmo landslide, highlighting significant movement 10 months before the disaster occurred.
A new public platform catalogs and curates data on salivary proteins, providing rich evidence for noninvasive diagnostics and precision medicine. The Human Salivary Proteome Wiki aims to harness the full potential of saliva for diagnosis, risk prediction, and therapy.
Researchers from Gero and Roswell Park Comprehensive Cancer Center discovered that biological age is changing over time, leading to reduced resilience. As people age, it takes longer to recover from stresses, and chronic diseases are linked to loss of resilience.
Research suggests that parents with a history of childhood trauma may struggle with emotion regulation, which can harm their children's emotional development. The study found that boys are more vulnerable to emotional regulation difficulties when their parents also struggled with emotion regulation.
Researchers at Duke University and Stanford University School of Medicine found that long-term wearable device data can quickly indicate illness, dehydration, and abnormalities in a patient's red blood cell count. Machine learning algorithms applied to the data enabled identification of previously unknown relations between smartwatch s...
Researchers used seismic CT scans and supercomputers to study slow slip earthquakes in New Zealand's Hikurangi subduction zone. The study found that tectonic forces build up before releasing through slow motion tremors, revealing key processes involved in modulating slow slip.
Researchers from Skoltech developed a simple redox-active polyimide with promising features in various energy storage devices. The new material showed high specific capacities, relatively high redox potentials, and decent cycling stability.
Researchers at RMIT University have developed a new 3D printing method that creates intricate biomedical structures, advancing tissue engineering and regrowing bones. The technique uses glue and a high school-grade 3D printer to create tiny implants with elaborate structures.
Rates of depression and anxiety were found to be higher among US coal miners compared to the general population. The study also identified a significant risk of posttraumatic stress disorder among current and former coal miners in the United States.
A study by Michigan Medicine found that female interventional cardiologists have comparable outcomes to their male counterparts in coronary angioplasties. Despite being significantly under-represented, they demonstrate excellent practitioner skills. The findings suggest benefits for female trainees considering the field.
A rare mutation causes Parkinson's disease-like symptoms by disrupting dopamine transport, suggesting treatments targeting the transporters could alleviate symptoms. A malaria drug helps alleviate movement problems in genetically modified fruit flies with the mutation.
Researchers used synchrotron X-ray techniques to study how gypsum dehydrates under pressure, revealing a small nudge that can have big consequences for geological processes. The findings suggest that increased tectonic stress can speed up dehydration and promote earthquakes.
Researchers developed an algorithm to compare cell types in different species, revealing conserved genes and cell type families across evolutionary distances. The mapping method accounts for changes over millions of years, enabling biologists to trace the trajectory of cell types in organisms along the tree of life.
A diverse range of microorganisms were discovered in the Kuzbass coal seam, including bacteria that can convert poisonous carbon monoxide into CO2. These microbes have unique metabolic capabilities, allowing them to thrive in extreme environments.
The study, led by Caicun Zhou, found that sintilimab-gemcitabine/platinum improved progression-free survival over placebo-gemcitabine/platinum. The results demonstrated a 46.4% reduction in disease progression or death risk.
A comprehensive analysis of 437 studies found narcissism is a significant risk factor for aggressive behavior worldwide. Higher levels of narcissism were linked to more aggression, including physical, verbal, and online cyberbullying.
A study by Monash University found a significant reduction in all four HPV genotypes in gay/bisexual men after implementing the school-based HPV vaccination program. The results suggest that male vaccination may lead to a potential reduction in anal cancer among gay and bisexual men in Australia.
The OIST-BNV Innovation Hub will provide financial investment and tailored business services to deep-tech startups, aiming to create high-tech industry and generate 10-20 new companies in the next few years. Startups can apply via an online portal from June 2021.
A new study from Clemson University identifies specific cell clusters in the brain of fruit flies affected by acute cocaine exposure. The findings show widespread changes in gene expression and distinct differences between males and females, potentially leading to therapeutic development.
The loss of genetic diversity is a pressing crisis that can have devastating consequences for ecosystems and human societies. Monitoring genetic diversity using DNA analysis can help detect vulnerabilities, but technology must be made available globally and data must be accessible to inform conservation efforts.
Researchers developed a method called SARSeq that enables large groups to be tested for SARS-CoV-2 with the same sensitivity as regular PCR tests. The method processes up to 36,000 samples in less than 48 hours and is highly specific and scalable.
A new study from Washington University School of Medicine found that low testosterone levels in men are linked to more severe disease. Men with low testosterone had a higher risk of requiring intensive care or dying from COVID-19, while those with higher testosterone levels were less likely to experience severe symptoms.
Newly discovered fish fossils from an eastern Egyptian desert site show that marine fishes thrived in at least some tropical areas during the PETM. The study provides a snapshot of an ecosystem during an extreme warming event and may provide insights for the future.
Researchers developed a holographic light collector that captures unused solar energy and increases the amount of solar energy converted by solar panels over the course of a year. The collector directs specific colors of sunlight to solar cells within the panel, resulting in an estimated five percent increase in annual yield.
A study published in BJPsych Open found that women with depression during pregnancy or a history of depression had reduced quality of mother-infant interactions. Despite this, all mothers and their babies improved over time, indicating potential for future attunement.
A study of ancient fish bones reveals that non-kosher fish were commonly consumed by ancient Judeans around the time of the biblical prohibition. The findings challenge traditional assumptions about the origin of Old Testament dietary laws and suggest a more complex history of food practices.
Emergency department visits for common conditions like appendicitis and miscarriage dropped significantly during the first wave of COVID-19, but there was no increase in adverse patient outcomes. Researchers found that management strategies remained unchanged, suggesting that patients who required emergency care continued to seek help ...
A study of nearly 100,000 individuals found that wearing accelerometers showed a significant association between moderate physical activity and reduced risk of atrial fibrillation and stroke. The researchers suggest that wearable devices could be used to promote public health by tracking and encouraging physical activity.
Pridopidine's neuroprotective effects are supported by new research that elucidates its mechanisms through activation of the Sigma-1 Receptor (S1R). The study highlights pridopidine's therapeutic potential and provides data supporting the role of S1R in neurodegenerative diseases.