A statistical modeling approach highlights predictive importance of local climate and human activity in determining wildfire probabilities. The analysis uncovered key roles for climate, human activity, fire history, and short-term climate variations in fire-prone regions.
Researchers from the University of Tsukuba used a fractional diffusion model to predict Lake Onuma's radioactivity concentration after the Fukushima accident. The study found that the radioactivity decrease is slowed down in closed lakes like Lake Onuma.
Researchers from the University of Minnesota Medical School published a framework to advance female equity in academic medicine and science. The framework proposes solutions such as engaging diverse community perspectives, communicating thoughtfully, and investing in diverse communities.
The Society for Neuroscience has partnered with Fujifilm as the Platinum sponsor of Neuroscience 2021, showcasing a diverse lineup of speakers and sessions. The virtual meeting features over 9,000 presenters and 1,000 poster sessions, prioritizing exceptional science from the global neuroscience community.
Hyperbaric oxygen therapy alleviated cognitive dysfunction, improved cerebral blood flow, and reduced amyloid burden in Alzheimer's disease models. In elderly patients with significant memory loss, HBOT showed an increase in cerebral blood flow and improvement in cognitive performance, demonstrating its therapeutic effects.
Recent research highlights microglia's involvement in Alzheimer's development and progression. A better understanding of microglial dysfunction may help explore signs and mechanisms of the disease, as well as enable microglia as a potential therapeutic target.
A team of researchers at George Washington University has identified DDR1 as a key molecule that prevents immune cells from entering and killing breast tumor cells. Deactivating this molecule allows immune cells to infiltrate the tumor and kill cancer cells, opening up new avenues for therapeutic agents.
A new study by Boston Children's Hospital researchers found that tissue-resident memory T cells in joints anchor themselves after a flare and wait for another trigger to react. Deleting these cells prevents arthritis flares from occurring, opening up new therapeutic avenues for rheumatoid arthritis treatment.
A team of scientists has developed a novel method to characterize microscope objectives without an aberration-less reference element, enabling error correction and precise data collection. Using nanoscale dipole scatterers, they create a nearly-perfect reference wave for measurement.
The American Gastroenterological Association (AGA) has released new clinical guidelines that recommend against extensive preprocedural testing to estimate clotting in patients with cirrhosis. This change aims to reduce the risk of morbidity and mortality associated with unnecessary blood clotting tests.
A recent survey of advanced breast cancer patients in the UK reveals that only 14% have been recruited to a trial, highlighting a need for improved access. Patients often face barriers, including clinician reluctance to discuss trials and a lack of patient-friendly databases.
New research highlights the importance of social support during pregnancy, finding that women with low levels of emotional or affectionate support are at increased risk of depression and anxiety. The study suggests that screening for social support and providing community-based services may help improve health outcomes.
A therapeutic antibody has been shown to unblock and normalise blood vessels inside cancerous tumours, enabling the more effective delivery of targeted cancer treatments. The findings also suggest that inhibiting LRG1 protein production can enhance the effectiveness of immunotherapies, including checkpoint inhibitors and CAR T-cell the...
Researchers have engineered E. coli to produce high levels of ectoine, a natural stabilizer of proteins and membranes, through metabolic engineering and fed-batch fermentation. This breakthrough increases efficiency and reduces the need for high-salinity culture mediums, paving the way for large-scale industrial production.
A recent study found that bilinguals use the same neural mechanism to combine words from different languages as they do with single-language expressions. This suggests that language switching is natural for bilinguals due to a combinatory mechanism in the brain that doesn't detect language changes.
A new study found that UK citizens experienced drastic changes in their daily routines during lockdowns, with parents of young children spending significantly more time on housework and childcare. This led to a reduction in paid work time for most people, with women with young children being particularly affected.
The Global Carbon Project predicts an increase of 4.9% in global carbon emissions in 2021, with fossil carbon emissions set to grow more than they fell in 2020. The report highlights the need for immediate global action on climate change as world leaders meet at COP26 in Glasgow.
Researchers found that combining thiazolidinediones with histone deacetylase inhibitors elicits robust anti-tumor responses in preclinical models of triple-negative and endocrine-refractory breast cancers. Higher levels of PPAR-gamma were associated with better prognosis.
The Gutenberg Gait Database provides a reference set of data for healthy individuals to diagnose and treat gait disorders. The database, compiled from 350 volunteers aged 11-64, offers processed raw data and ready-to-use data for orthopedic institutes and research organizations.
A team from UNIGE has developed a new system to secure data transfers using the principle of relativity. This approach enables users to identify themselves confidentially without disclosing personal information, making it suitable for cryptocurrencies and blockchain applications.
Trials that met their primary endpoint were more commonly published in journals with higher impact factors, suggesting a correlation between trial outcome and publication quality. Additionally, publications of trials leading to FDA approvals and those in high-impact journals were associated with increased Research Citation Rates.
Researchers developed a color-changing indicator that detects rising levels of alkaline phosphatase, forecasting phytoplankton growth and impending algal blooms. The portable system reliably detected enzyme activity using smartphone scanning apps, potentially enabling real-time field monitoring and prediction.
A study suggests sacubitril/valsartan is no better than valsartan alone in patients with severe heart failure, but may be slightly safer. The treatment showed no improvement in biomarker levels or clinical outcomes for sickest patients.
A new study from Italy found that students with high conscientiousness and openness tend to perform better academically. The research suggests that personality traits play a significant role in university success.
A RMIT-led collaboration demonstrates large in-plane anisotropic magnetoresistance (AMR) in monolayer WTe2, a quantum spin Hall insulator. The team successfully fabricates devices and observes typical transport behaviors, showing promise for future low-energy electronics.
Researchers found that a receptor in the brain detects nutritional state and regulates puberty timing and growth rate, explaining why humans have been growing taller and reaching sexual maturity earlier over the past century. The discovery has immediate practical implications for testing children with growth delays.
Researchers discovered that spiny mice can regenerate severely damaged kidneys without scarring, a process triggered by unique transcriptional programs in their genome. This finding offers new hope for treatments of end-stage kidney disease and fibrotic diseases.
A study of 21 mothers found that those infected with SARS-CoV-2 during pregnancy had a varied immune response in their newborns, resulting in some infants developing antibodies and others not.
Research reveals SARS-CoV-2 can enter the brain and affect neural function, leading to symptoms like headache, depression, and fatigue. Many people experience lingering cognitive or neurological problems months after initial recovery.
Researchers at Children's Hospital of Philadelphia have developed a novel therapy that targets proteins essential for tumor growth and survival. Using a multi-omics approach, they identified peptides unique to neuroblastoma tumors, which are then targeted by peptide-centric chimeric antigen receptors (PC-CARs).
Cancer cells alter the large blood vessels in lymph nodes, disrupting their function and allowing tumor cells to evade attack by the immune system. The researchers identified identical findings in mice and humans, providing a deeper understanding of how lymphomas protect themselves from the body's defenses.
A new study from the University of Eastern Finland introduces an electric soot collector that achieves a 45% fine particle reduction efficiency in logwood-fired masonry heaters. The technology uses natural charges of flames to collect particles, but further optimization is needed for higher reduction efficiencies.
A study found that younger B-cell non-Hodgkin lymphoma survivors are at a higher risk of developing age-related diseases, including renal failure, pneumonia, and nutritional deficiencies. The research suggests that aggressive treatment regimens may be the underlying factor contributing to this increased risk.
Researchers uncover intricate cellular response to rotavirus damage in intestinal epithelium, finding tuft cells contribute to repair process through production of immature enterocytes. The study provides new understanding of gut healing mechanisms and potential therapeutic targets.
The University of Huddersfield has partnered with LinkedIn Learning to offer academic credit for select online learning paths. Learners can earn credits in fields like data science, graphic design, digital marketing, and project management, enabling them to move seamlessly into undergraduate or postgraduate degree programs.
Researchers have proposed new radioisotopic dates for Ediacaran fossil assemblages and carbon isotope perturbations, providing age constraints for both. The study reveals two negative carbon isotope excursions in the 575–550 Ma period, with the Shuram event occurring between 575 Ma and 565 Ma.
A study found that large herbivore biomass is only present in African reserves, with a close correlation between plant productivity and consumer biomass. In contrast, non-African ecosystems have low herbivore densities, even in protected areas.
A new study found that whole genome sequencing increases the diagnosis of rare genetic disorders by 31%, shortening the diagnostic odyssey for affected families. This approach provides opportunities for future research and can identify non-mitochondrial disorders with specific treatments.
A University of Cambridge study reveals that periodic caterpillar outbreaks improve lake water quality but increase CO2 emissions by altering nutrient cycling and favouring greenhouse gas-producing bacteria. This phenomenon is likely to worsen as climate change expands the insects' range, threatening northern forests.
Researchers aim to make drug purification more efficient and scalable by understanding unwanted element interactions. They explored ligand-surface interactions using NMR spectroscopy and simulations.
Researchers used a yeast model to understand the dynamics of early-stage ribosomal subunit assembly, discovering snR190 functions as an RNA chaperone. The study also identified Dbp7 as the enzyme responsible for dissociating snR190 from ribosomal RNA precursors.
Scientists have engineered enzymes to manufacture molnupiravir, resulting in a shorter and higher-yielding synthesis. The new method reduces the risk of hospitalization and death from COVID-19 for newly diagnosed patients, showing promise as an antiviral treatment.
Scientists call for scientifically-informed reforms to manage overabundant kangaroo populations, addressing animal welfare, conservation and environmental concerns. The special edition of the journal features research papers on sustainable monitoring and management practices to reduce harm to wildlife species.
A 26-year study on wild white-footed mice found that mice with physical impairments survived and thrived at a rate similar to their unimpaired counterparts. Mice with impairments had greater mass and larger home ranges, but no evidence of decreased fitness.
Researchers uncover how sensory inputs and cognitive processes interact in the brain to create our perception of the world. The study explores the neural basis of perceptual phenomena, shedding light on disorders like ADHD, autism, and Alzheimer's disease.
A prospective-longitudinal study found that pregnant women with lower emotional stability and personality traits tend to have worse subjective birth experiences. Unexpected events like Caesareans can exacerbate these negative experiences.
Researchers found that melanomas detected during routine skin checks were associated with a significantly lower all-cause risk of death, but not melanoma-specific death. The study involved 2,452 patients in Australia and suggests a potential benefit to regular skin cancer screenings.
Researchers describe a simple argument showing that basins in high-dimensional systems should look like high-dimensional octopi. The volume of these basins cannot be correctly approximated by a hypercube, which fails to encompass the vast majority of points in the basin.
A recent survey reveals a new method using cloud-cleared radiances improves forecasting of high-impact weather events like hurricanes and typhoons. The technique is now being applied to numerical models for enhanced daily forecasts.
A team of psychological scientists and criminologists recommend testing eyewitness memory only once to prevent contaminated memories from convicting innocent people. The first identification is the most reliable test, which can avoid further contamination and ensure justice.
Researchers have sequenced the quillwort genome, uncovering unique genetic mechanisms regulating CAM photosynthesis in these aquatic plants. The study found differences in phosphoenolpyruvate carboxylase function between quillworts and terrestrial plants.
A recent study found that sugary drink taxes only reduce purchasing when price tags mention the tax, but not the amount. Consumers tend to overestimate how much the tax is, making them more willing to pay it if they know the true size of the tax.
A recent study estimates that the net manufacturing costs for 100 million doses of COVID-19 vaccine ready for shipping range from $0.54 to $0.98. Companies charge significantly higher prices, despite discounts and tiered pricing for low-income countries, which are likely to prolong the global pandemic.
Researchers created a laboratory to simulate comets in space-like conditions, measuring their properties and evolution. The CoPhyLab chamber allows scientists to compare samples and track gas evaporation and particle loss, providing insights into comet formation and solar system history.
A recent study published in Behavioral Sleep Medicine found that people who wake up, smoke, and return to sleep are more likely driven by stress than nicotine addiction. To help these smokers quit, researchers recommend addressing their psychological distress and developing treatments that go beyond nicotine dependence.
Researchers at Washington University in St. Louis have developed a way to train microbes to produce a readily usable biofuel from CO2, solar panel-generated electricity and light. The resulting n-butanol is an authentically carbon-neutral fuel alternative that can be used in blends with diesel or gasoline.
Defects in surgical care cost the American health care system over $12 billion annually. A holistic approach through Centers of Excellence can address these defects, increasing quality, patient experience, and reducing costs.
A new study at the University of Missouri found that telehealth reduced stress for nursing home residents while increasing access to convenient care. However, it also removed socialization opportunities and created confusion for residents with cognitive difficulties.
The need for new antibiotics is critical due to rising antibiotic resistance, which kills over 35,000 people annually in the US. Research by Harvard Medical School aims to develop better antibiotics by targeting essential bacterial proteins.
A new study suggests that black holes grow in lockstep with the expanding universe, a phenomenon called cosmological coupling. This idea improves the explanation for large black hole masses observed in gravitational wave observatories.