A new study published in Environmental Research found that exposure to high levels of air pollutants like NO2 and PM2.5 and low distance to green or blue spaces are associated with worse health-related quality of life in COPD patients.
A comprehensive list of threats to Australian plants and animals reveals stark news about the future for some iconic species. The study provides precise data to better direct conservation efforts, categorizing and addressing threats like habitat loss, invasive species, and climate change.
Female mice exhibit increased production of social calls and non-vocal behaviors when reunited with others after acute isolation, suggesting a pathway for studying brain mechanisms underlying social motivation and mental health.
A recent study explores the plant immune system using chimeric maize leaves with an auto-active R protein. Researchers found that Rp1-D21 triggers a defense response without recognition events, leading to cell death in affected areas but not neighboring cells.
A team of astronomers has uncovered the physical and chemical effects of a protostellar jet in the Orion Nebula, including compression, heating, and destruction of dust grains. The study reveals a significant increase in gas phase abundance of heavy elements such as iron and nickel.
Scientists have sequenced the Indian wolf genome, revealing it to be one of the world's most endangered and evolutionarily distinct populations. The study suggests that Indian wolves may represent the most ancient surviving lineage of wolves.
Researchers have created a global database of 63 tailings flows since 1928, revealing catastrophic events occur every two to three years on average. The study highlights the importance of understanding water-to-solids ratios and downstream terrain in preventing mass casualties and environmental damage.
A nationally representative survey found that 72% of people with food allergies were unaware of oral immunotherapy as a treatment option. The study highlights the need for more accessible and equitable outreach efforts to ensure all patients can benefit from recent advances in food allergy treatments.
Researchers compared antibody responses in adults receiving Pfizer/BioNTech and Moderna COVID-19 vaccines. The study found differences in antibody responses among young and older adults. Younger recipients showed higher antibody levels after vaccination.
A recent study found that 26-45% of people with atrial fibrillation fail to adhere to their prescribed direct-acting oral anticoagulants due to cost and bleeding concerns. Researchers interviewed 42 adults who had stopped or reduced dosing, citing these reasons as major barriers to adherence.
Researchers found that prior exposure to common cold coronaviruses boosts the body's immune response to SARS-CoV-2, with cross-reactive T cells recognized by the immune system. The study's findings suggest a protective effect against severe disease and improved vaccine efficacy in younger individuals.
Researchers at Princeton University have identified a crucial part of the mechanism by which C. elegans worms can help others avoid a pathogenic bacterium through a process involving a retrotransposon called Cer1. This finding suggests that Cer1 may give worms an advantage in their battle with pathogens.
Researchers have discovered that cancer formation depends on a collaboration between DNA mutations and specific genes turned on in cells. Cells with oncogenic competence access locked-up genes, requiring specific proteins as keys to form melanoma. This finding offers potential therapeutic targets for patients.
Plants delay flowering when it's too cold due to florigen sequestration in lipid membranes. At low temperature, florigen binds to phosphatidylglycerol, delaying flowering until temperatures rise.
The study provides a high-quality genome sequence of Aristolochia fimbriata, shedding light on angiosperm evolution, floral development, and chemical biosynthesis. The researchers identified two overlooked whole-genome duplications in Piperales and clarified the time of previously reported WGDs in Magnoliales and Laurales.
A new analysis suggests that the pace of vaccination should directly dictate the lifting of COVID-19 restrictions to boost freedoms and minimize new waves of infection. The study's findings suggest that further severe waves can be avoided if restrictions are lifted no faster than the pace dictated by vaccination progress.
The Canadian Research Knowledge Network (CRKN) has partnered with the MIT Press to manage central licensing and invoicing for Direct to Open (D2O), a framework for open access monographs. Twenty-eight libraries have elected to participate, earning exclusive benefits such as archive access and discounting on trade books.
A study using environmental DNA found that mountaintop coal mining impacts 40% fewer species in Appalachian streams. The team detected 28 species of fish in all 93 sampled mined streams, comparable to traditional methods.
The study found that robotic-aided pedicle screw placement showed accurate positioning, even for experienced surgeons, with a significant decrease in time required. The technology saved time in the operating room, making it an efficient option for spine surgery.
Astaxanthine attenuates cisplatin ototoxicity in vitro by reducing reactive oxygen species (ROS) overexpression, mitochondrial dysfunction, and apoptosis. In vivo, AST protects against cisplatin-induced hearing loss by promoting cell survival and reducing ROS overexpression.
Researchers have identified an N-benzyl hydroxypyridone carboxamide hit that inhibits HCMV in submicromolar range, exhibiting a structure-activity relationship and good selectivity index. The compound also displays favorable ADME properties
A UC Riverside-led study identifies how loss-of-function mutations in the gene PTPN2 affect intestinal epithelial cells' ability to maintain a barrier. The researchers found that increased fluid loss and diarrhea are linked to the mutation, which can be reversed by treating cells with synthetic matriptase.
A virulent Salmonella Enteritidis strain has been sequenced from two consecutive poultry flocks in North Carolina State University. The strain, SE_TAU19, exhibits seven antimicrobial resistance genes and 120 virulence genes, posing a threat to human health. Genome sequencing provides valuable data for tracing outbreaks and preventing f...
A large-scale study of over 300,000 children in Australia found that those hospitalised with chronic illnesses were at a significantly higher risk of poor academic performance. The study, published in Archives of Disease in Childhood, highlights the need for additional support for these students.
Ecosystem transformation is a highly dynamic and complex process that can occur gradually over various timescales. Adaptive learning, creative approaches, and close partnerships between scientists, decisionmakers, and stakeholders are needed to address the challenges of climate change.
Researchers at the University of Bath found that large food companies and advertisers opposed Transport for London's 2019 ban, challenging its effectiveness and attempting to undermine policy. The ban was implemented despite commercial opposition, and its success sets a positive precedent for other authorities planning similar bans.
A new study led by UC researcher Daniel Woo found high blood pressure to be a significant risk factor for strokes in Black and Hispanic patients. The study also identified sleep apnea as a novel risk factor for intracerebral hemorrhage (ICH) strokes, which are often deadly and cause high disability.
A new University of Central Florida study found that using deadline-ism messaging in climate change communications increases perceptions of the threat and support for government action. Participants who read articles with deadlines supported more political climate change action than those without deadlines.
This study compared drugs associated with hepatotoxicity in the FDA's FAERS database, finding that mitochondrial mechanisms are a leading cause of drug-induced liver injury. The top four drugs with the highest risk were associated with mitochondrial mechanisms, and older patients and females were more likely to be affected.
New research from Edith Cowan University reveals responders to the 9/11 terrorist attacks are still suffering 20 years later, with many facing significant health issues related to the event. Cancer and mental health concerns are particularly prevalent among responders.
The article examines how higher education has shaped state-building and political economies since WWII. Researchers propose a four-point model and categorize state attitudes towards education into three categories: national asset, citizen's right, and commodity.
Researchers developed a method to overlay a virtual scale on acquired endoscope images in real-time, allowing accurate estimation of colorectal polyp sizes. The approach uses triangulation principles and minimal image processing, enabling cost-effective diagnosis without adding extra instrumentation.
Researchers at Huntsman Cancer Institute have generated the first 'atlas' of human melanocytes, revealing different types and their associations with various skin tones, subtypes of melanoma, and treatment responses. These discoveries aim to improve targeted treatments for melanoma.
A new study shows that polar vortex disruptions most favorable for extreme US winter weather are increasing, with Arctic change likely contributing to the trend. The analysis demonstrates that a 'stretched' polar vortex state is more common and leads to severe winter weather.
A recent study has identified nearly half of the fastest-evolving human genes as playing a crucial role in rewriting the course of human brain development. The research used an innovative approach called CaptureMPRA to analyze the function of Human Accelerated Regions (HARs) in regulating gene expression in the brain.
Using data from the Very Large Array Sky Survey, researchers have identified a luminous radio source consistent with an expanding supernova remnant. The discovery is associated with an unidentified x-ray transient and suggests the explosion produced a relativistic jet, supporting predictions for merger-triggered supernovae.
A new study found that birds and mammals evolved into new species at higher rates where the land has risen most over the past three million years. This effect was found to be greater than historical climate change, present-day elevation, and temperature in driving speciation.
A new algorithm, Phe2vec, accurately identified patients with certain diseases, outperforming traditional methods in classifying diagnoses. The study suggests that this automation will facilitate further research in clinical informatics.
A recent study analyzed data from the Centers for Disease Control and Prevention's coronavirus self-checker to identify symptoms reported by adults with and without SARS-CoV-2 infection following a loss of taste or smell. The results revealed distinct symptom profiles for individuals with and without the virus.
A new study reveals women receive less credit for their work, experience more disagreements over authorship, and are often excluded from future collaborations. The authors call for standardization in authorship decisions and universities to provide pathways for researchers to communicate concerns.
A study found that COVID-19 stay-at-home orders in Chicago were associated with increased rates of reported domestic violence, particularly among minority groups. The study suggests that pandemic policies may exacerbate existing inequalities in access to resources and support for survivors of domestic violence.
A new study finds that HPV vaccination will significantly reduce rates of throat and mouth cancers in younger age groups, but the overall impact may not be seen until 2045. The study projects a substantial decline in oropharyngeal cancer rates among well-vaccinated individuals aged 36-45 and 46-55 between 2018 and 2045.
Researchers from SMART and collaborators have developed the first nanosensor to detect synthetic auxin plant hormones, transforming the screening process. The sensors enable real-time monitoring of plants' response to compounds like herbicides without causing damage.
The new molecular device has exceptional memory reconfigurability, allowing for enhanced computational power and speed. It can be reconfigured using voltage to embed different computational tasks, making it a potential game-changer in edge computing and applications with limited power resources.
Researchers have discovered a simple and rapid method to measure the T-cell immune response to SARS-CoV-2, which causes COVID-19. The Cytokine Release Assay (CRA) test can reliably identify and quantify specific T cells in vaccinated individuals or those who have recovered from the disease.
Researchers have uncovered thousands of new regulatory regions that control disease-linked genes, providing a significant step forward for genomics-driven precision medicine. This new resource, available worldwide, could help identify markers revealing which patients will benefit most from specific treatments.
A new study examines the similarities and differences among disease activity indices used to monitor rheumatoid arthritis. Researchers found that while there are high correlations among the indices, they were not interchangeable, highlighting the need for further analysis of RA in patients using various indices.
A study found that people who feel their sense of autonomy is unmet by government incentives like vaccine passports are less likely to take the COVID-19 vaccine. The research highlights that public health incentives might affect people's vaccination decisions in unintended ways, potentially undermining herd immunity.
A new technique developed by KAIST researchers uses a 'nanoscale focus pinspot' to isolate and enhance the quality of quantum emitters. By reducing unwanted background noise without altering the optical properties, this method enables the production of single, pure photons with improved purity.
A study published in International Journal of Environment and Public Health Research reveals that oral bacteria, specifically P. gingivalis and Lactobacillaceae families, are associated with periodontitis. Genetic differences among hosts contribute to susceptibility to pathogens, but the oral microbiome plays a more significant role in...
Researchers have created the first 3D-printed stellar nurseries, revealing features often obscured in traditional renderings. The models, about the size of a baseball, display swirling clumps and filaments, allowing for better understanding of star formation and physical processes.
Scientists have created a high-spin divacancy color center in silicon carbide with exceptional optical and spin properties. This achievement enables the development of room-temperature solid-state quantum storage and scalable quantum networks based on SiC spin color centers.
A study by Anglia Ruskin University found that weaker internal connections between the brain and organs are linked to negative body image. Adults with less efficient brains at detecting internal messages are more likely to experience body shame and weight preoccupation.
A CDC analysis of National Healthcare Safety Network data revealed a significant increase in four types of healthcare-associated infections in U.S. hospitals during the COVID-19 pandemic, with central line infections rising by 46-47% compared to pre-pandemic rates.
Recent research published in Nature Cell Biology reveals the complex role of transient regeneration-activating cell states (TRACS) and other cell types in planarian flatworm regeneration. TRACS were found to exist near and distant from wound sites, contributing to regenerative capacity.
A new analysis platform developed by Ohio State University scientists combines genetics and phytochemical data to improve the health benefits of apples. The platform has potential to reduce breeding time and enable data-driven assessments of how to boost apple nutrition.
A study based on US blood donations found increasing seroprevalence of SARS-CoV-2 antibodies over time, with variations by age, race, and geographic region. Seroprevalence estimates the prevalence of SARS-CoV-2-specific antibodies due to natural infection or vaccination.
A study of highly vaccinated health workers found that COVID-19 vaccines lost effectiveness in protecting against symptomatic infection by July, with only 65% protection remaining. The emergence of the delta variant and lifting of masking mandates contributed to this decline in vaccine efficacy.
MUSC Hollings Cancer Center researchers discovered a novel mechanism showing how a certain gene mutation can allow tumors to evade detection by the immune system in colorectal cancer patients. The study found that APC mutations lead to increased levels of PD-L1, which allows tumors to evade T-cell function and increase immunosuppression.
A new study by MIT researchers found that crowdsourced accuracy judgments from groups of normal readers can be virtually as effective as the work of professional fact-checkers. The study deployed 1,128 U.S. residents who rated news stories and found that their average ratings correlated with those of professional fact-checkers.