Researchers found a new role for enzymes regulating genome function, which is linked to diseases such as brain tumors, blood cancers, and Kleefstra syndrome. The discovery could help understand these diseases and develop new treatments.
Researchers suggest that societal training shapes gendered perceptions of domestic tasks, with women more likely to see 'to be done' affordances. Men can improve their sensitivity to these affordances through conscious effort and habit formation.
A randomized trial found that non-invasive interventions for treating spine pain improved disability and quality of life but did not decrease healthcare spending. Both treatments provided a small but significant reduction in pain-related disability at 12 months.
A new study by UCLA and MIT Press researchers finds US universities are rich in data but struggling to capture its value. Universities lack needed coordination and expertise, making it difficult to integrate systems and reduce redundancies.
A recent study published in JAMA Network Open found that women who followed a Mediterranean diet before conception had a significantly lower risk of developing preeclampsia during pregnancy. The study also showed that a higher intake of vegetables, legumes, and fish was associated with a lower risk of adverse pregnancy outcomes.
Researchers discovered that distinct layer-specific neuronal circuits in the primary motor cortex modulate both sensory and emotional components of chronic pain in mice. Activation of specific pathways suppressed sensory hypersensitivity to pain and reduced negative emotional and behavioral components.
The Tibetan Plateau's frozen ground is experiencing diverse variations in thawing due to uneven wetting under climate change. The study found that arid regions have become warmer and wetter, while humid regions have become warmer but drier. This has led to a reduction in permafrost area by 28% as substantial wetting in arid areas exert...
Scientists at Washington University in St. Louis found that manganese oxides can be formed without atmospheric oxygen under Mars-like conditions. The study, published in Nature Geoscience, used kinetic modeling to show that halogens like chlorate and bromate can convert manganese into minerals thousands of times faster than by oxygen.
Researchers discovered a new mode of vertical mother-to-infant microbiome transmission, where microbes shared genes with each other. The study found links between gut metabolites, bacteria, and breastmilk substrates, influencing infant development before and after birth.
Researchers at Michigan State University have found a link between climate change and nutrition, showing that increased carbon dioxide levels can affect plant metabolic processes. The study highlights the importance of understanding how plants use amino acids to produce proteins, as this may impact their nutritional value.
A study found that children exhale fewer small particles, which are less likely to spread diseases like COVID-19. Larger particles produced by adults and children can transmit infections equally well, highlighting the importance of wearing high-efficiency masks for disease prevention.
Researchers found that microplastic mass sequestered in seafloor sediments mimics global plastic production from 1965 to 2016. The study revealed a tripling of microplastics deposited on the seafloor since 2000, with accumulation rates mirroring global use of plastics.
A new Japanese study found a substantial rise in renal replacement therapy incidence due to nephrosclerosis, while rates for diabetic nephropathy decreased. The number of patients with nephrosclerosis as a primary kidney disease is increasing, suggesting age-specific incidence rate increases
A randomized trial shows that patients undergoing partial knee arthroplasty (UKA) experience faster functional recovery in walking speed and mobility tests compared to those who had total knee arthroplasty (TKA). UKA also resulted in shorter operative times, reduced blood loss, and improved functional outcomes.
Researchers developed an iEMG classifier framework for detecting myopathy and neuropathy, achieving high accuracy in three muscle types and low computational time. The study showed promise for real-time implementation, aiding clinicians in making quick and accurate diagnoses.
Researchers used auto-encoder technique to analyze 150 XRD patterns of magnetic alloys, identifying clusters and fine-tuning alloys by detecting relevant peaks. The approach enables accelerated development of high-efficiency materials with low environmental impact.
A large study of over 20,600 children found that living in higher-opportunity neighborhoods at birth was associated with a lower average body mass index trajectory and a lower risk of obesity from childhood to adolescence. Initiatives targeting neighborhood environments may help prevent excess weight in children.
A Mediterranean diet has been associated with a reduced risk of adverse pregnancy outcomes. The study found a dose-response relationship between the intake of Mediterranean diet and lower risk of such outcomes.
A new study from the University of Virginia Health System found that mRNA booster shots increase the durability of antibodies to COVID-19. The boosters led to longer-lasting antibodies, even in those who had previously recovered from a COVID-19 infection.
Osaka Metropolitan University scientists have developed a novel protein detection method that allows for ultra-fast and highly sensitive detection of proteins, enabling early disease diagnoses. The method uses light-induced acceleration of antigen-antibody reaction to detect attogram-level proteins within 3 minutes.
Researchers developed a new spatial-omics technology called DISCO-MS to detect early molecular changes in diseases. This approach allows for the characterization of diseased cells in intact tissues, revealing new biomarkers and therapeutic targets for conditions like Alzheimer's disease and atherosclerosis.
Researchers at Drexel University used GPT-3 to spot early signs of Alzheimer's in spontaneous speech, achieving 80% accuracy. The program analyzed word-use, sentence structure and meaning from transcripts to identify characteristic profiles of Alzheimer's speech.
A study by Johns Hopkins Medicine researchers suggests that the brain's ability to focus on individual sounds amidst ambient noise declines with age, leading to a 'fuzzy' sound stage. The team trained old mice to filter out background sound, showing promise for treating age-related hearing loss.
A study from Wuhan University demonstrates an 'exceptional nexus' that exhibits diverging responsivity and ultra-enhanced signal-to-noise ratio, resolving challenges for sensing applications. This finding opens new avenues for ultrasensitive measurements.
Researchers at Helmholtz-Zentrum Berlin discovered that high-energy X-rays can cause damage to bone collagen, even at low irradiation doses. The study used powerful X-ray sources and sensitive detectors to examine the effects on fish and mammalian bone samples.
Researchers have developed a new imaging method that captures the light-induced phase transition in vanadium oxide (VO2) with high spatial and temporal resolution. The study reveals that pressure plays a larger role in these transitions than previously expected, challenging previous conclusions.
Researchers found that white matter hyperintensities are independently associated with premature brain aging, leading to progressive age-like brain atrophy. The study used machine-learning algorithms to estimate brain age and analyzed the relationship between WMH load and BrainGAP scores.
Researchers identified six genes associated with dementia risk in people of African ancestry, differing from those found in European populations. The study highlights the need for increased representation of non-European ancestry groups in genetic research to address health disparities.
Researchers discovered a neural system for self-localization in larval zebrafish using whole-brain functional imaging. The multiregional hindbrain circuit integrates visual information to form a memory of past displacements, correcting for accumulated displacements over many seconds.
A new lung cell atlas has revealed 11 new cell types and a previously unknown immune niche in the airways, which could help prevent or treat respiratory diseases. The atlas provides detailed insights into how cells interact and communicate with each other in healthy lungs.
A study suggests that increasing the inefficiency of physical activity, like walking in the style of Monty Python's Mr. Teabag, can have important public health benefits. Adults could achieve global physical activity targets by doing just a few minutes of teabag-style walking per day.
University of Illinois researchers derived the depth profile of electric double layers using statistical analysis and electrostatic calculations. They developed a new method, CP-3D-AFM, to experimentally quantify the charge distribution at electrode-electrolyte interfaces.
A study published in The BMJ found that people who believe in conspiracies and reject the covid-19 vaccine are more likely to endorse mythical causes of cancer than non-conspiracists. However, awareness of actual causes of cancer is generally higher among these groups.
A team of simple robots, nicknamed RAnts, use photormones to escape a corral and perform complex tasks. The research reveals how collective cooperation can arise from simple rules, applicable to solving problems like construction, search and rescue, and defense.
Researchers have created a hydrogel-based material that can absorb up to three times more water-based liquid than traditional paper towels. The gel sheets also show promise in absorbing thick liquids, such as blood and syrup, with high efficiency and stability.
Heidelberg researchers decoded genetic regulation of sperm formation across various mammal species, including humans. The study revealed a time-related pattern of gene expression differences, highlighting the rapid evolution of spermatogenesis.
Researchers discovered that cold-water coral reefs optimize their growth in response to ocean currents, capturing organic matter and resources. This self-organization allows them to thrive in deep environments, serving as architects of ecosystems and habitats for diverse species.
A new gene therapy treatment has shown promising results in a clinical trial for Artemis-SCID patients, improving their immune function and reducing treatment complications. The treatment involves adding a healthy copy of the Artemis gene to the patient's own cells, resulting in improved T-cell and B-cell immunity.
A study reveals that big dynorphin, an endogenous opioid peptide, protects neurons against β-amyloid accumulation. The research suggests that big dynorphin can hinder the interaction between β-amyloid and form aggregates, promoting a neuroprotective effect.
A retrospective study found that hematopoietic stem cell transplants delayed disability progression and improved symptoms in people with active secondary progressive multiple sclerosis. The study suggests that these transplants may be more effective than some MS medications, but further research is needed to confirm the findings.
A new method bridges the quantum and classical worlds, enabling interaction-free detection of microwave pulses with a superconducting circuit. This breakthrough demonstrates genuine quantum advantage using a simpler setup, with potential applications in quantum computing, optical imaging, and cryptographic key distribution.
Researchers at Kyoto University have developed nanoantennas that significantly increase the efficiency and photoluminescence of white LEDs by replacing aluminum with titanium dioxide. This breakthrough enables the creation of intensely bright yet energy-saving solid-state lighting solutions.
Scientists discover new Australian bush tomato species, Solanum scalarium, to promote equal and safe access to nature. The study emphasizes the importance of addressing environmental injustices and increasing participation from diverse groups in outdoor activities.
A rare fossil discovery provides new insights into the diet of Microraptor, a bird-like dinosaur with four wings. The find suggests that Microraptor was an opportunistic predator feeding on various species, including fish, birds, lizards, and small mammals.
The UTSA-led Consortium on Nuclear Security Technologies (CONNECT) has received a five-year, $5 million grant from the U.S. Department of Energy's National Nuclear Security Administration. The program aims to educate and train the next generation of scientists and engineers in nuclear security, with a focus on underrepresented students.
Scientists have found that carefully planned patches of diverse vegetation can increase biodiversity and boost yields for farmers. By engaging local communities and co-designing restoration strategies with them, researchers demonstrate the potential to minimize fragmentation and enhance connectivity in Amazon landscapes.
A team of researchers from Cold Spring Harbor Laboratory has made a breakthrough in understanding the deadly brain cancer glioblastoma. By linking the BRD8 protein to another key protein, P53, they have identified a potential target for new treatments that could extend patient survival and improve outcomes.
A new study found that only 6.1% of US firms with wildfires in their headquarters county disclose wildfire risks in required federal filings, highlighting a gap in transparency and risk management. Firms are more likely to disclose risks when they have previously experienced wildfires, and the most disclosure-sensitive firms are those ...
A team of scientists from TIBI, UIC, and POSTECH has elucidated key points on how cartilage generation is facilitated and alternative bone formation can be avoided. They found optimal conditions for better cartilage regeneration while reducing excessive cartilage formation using human mesenchymal stem cells.
The unemployment rate for people with disabilities has declined significantly, dropping below pre-pandemic levels. This decrease is attributed to gains in employment-to-population ratio and labor force participation rates for people with disabilities.
A new study published in the American Journal of Roentgenology found significant cost savings by eliminating sedation during pediatric brain MRI examinations. The analysis calculated costs for sedated, nonsedated, and limited MRI exams at three US hospitals, revealing that labor costs were the largest expense category.
Researchers found that providing language descriptions of tools can accelerate a simulated robotic arm's learning of tool manipulation. The team used GPT-3 to obtain tool descriptions and showed improved performance in tasks such as pushing, lifting, sweeping, and hammering with new tools.
Researchers at UCLA Health have found that masks can prevent not only COVID-19 but also whooping cough, while obesity is linked to an increased risk of stroke and cognitive impairment. The institute has also designed a clinical trial to reduce the use of low-value treatments for Alzheimer's disease.
Researchers at the University of Helsinki found that distinct hybrid wood ant populations evolved independently towards the same direction, indicating predictable outcomes. The study suggests that hybridization can help species cope with a warming climate by combining temperature ranges from both species.
A new study found that chronic inflammation in lactating mothers with obesity may contribute to low milk production. The researchers analyzed fatty acid and inflammatory marker profiles in blood and breast milk, finding a strong correlation between the two in non-obese mothers but not in those with chronic inflammation.
Researchers found that biology textbooks published between 1970 and 2019 provided insufficient climate change information, with median sentence counts decreasing over time. Climate coverage has varied substantially, but actionable solutions decreased significantly since the 1990s.
Researchers found that a senolytic drug can preserve the biliary tract's regenerative capacity in liver cells damaged by cold storage. This discovery could lead to improved liver transplant success rates, saving lives and reducing costs associated with transplant failure.
A nationwide cohort study in Sweden found that elite male football players have a lower risk of alcohol and drug related disorders compared to the general population. This protective effect was seen only for those who first played in the 1960s and later, while players from earlier eras had similar risks as men from the general population.
A new catalyst system has been developed for selective and efficient urea production. The catalyst features a multi-heterojunction interfacial structure that enhances high performance by minimizing incomplete charge transfer and suppressing by-product reactions.
Researchers found that consumers pay more when asked to make payment decisions after receiving the product, especially for high-value offerings. Conversely, lower values are paid when decisions are made before receipt. This timing effect can inform businesses and organizations implementing pay-what-you-want pricing mechanisms.