A study published in CJASN found that symptoms related to kidney failure worsened before dialysis but stabilized after initiation. The analysis revealed a significant decrease in symptom number and burden after dialysis, particularly for fatigue and sexual symptoms.
A handheld diagnostic lab developed by UCLA researchers can fully automate pooled testing and detect multiple diseases, reducing costs and usage of scarce supplies. The technology can be easily manufactured, deployed, and performed at a doctor's office or mass testing sites, helping authorities prepare for future pandemics.
The IOF and ESCEO position paper recommends retaining the current WHO diagnostic criteria for osteoporosis, which has served the field well. The paper suggests that distinguishing between diagnostic and intervention thresholds can help improve treatment of patients at high risk of fractures.
USCF researchers have developed a new approach called CAR Pooling to compare different re-engineered T cells with varying molecular features. The screen revealed new and surprising receptors that make these therapeutic cells more powerful, promising a better treatment for blood cancers.
Ocean biodiversity is declining, with shark populations on the rise in danger despite successful conservation efforts for tunas and billfishes. Effective management has allowed tuna and billfish to recover over the past decade, but sharks remain undermanaged.
A study by the American College of Allergy, Asthma, and Immunology found that pollen levels are lowest during early morning hours, with lower counts occurring between 4:00 a.m. and noon. This information can help individuals with pollen allergies plan their outdoor activities accordingly.
A study by Osaka Metropolitan University found that teaching fall prevention using home floor plans reduced falls in older hospital patients by 97% compared to a control group. The intervention group had no falls within two months of discharge, while the control group experienced 7.7% falls.
Researchers found that IV administration of the experimental cancer vaccine, SNAPvax, boosted cytotoxic T cells capable of infiltrating tumor cells and engaged the innate immune system. This approach overcomes tumor-induced immunosuppressive activity, enabling enhanced T-cell immunity.
Researchers have discovered a new process that uses fuel to control non-living materials, similar to living cells. This breakthrough enables the creation of soft robots that can sense their environment and respond accordingly.
The Acoustical Society of America will hold its 183rd meeting in Nashville from Dec. 5-9, bringing together experts to share experiments and applications on diverse topics such as machine learning and medical diagnostics. Lay language papers will also be shared, providing summaries of presentations written for a general audience.
Researchers have discovered that targeting a specific mutation in fibrolamellar tumors can reduce tumor growth in mice, offering a promising approach to treating this nearly incurable cancer. The findings highlight the potential for novel therapies against an intractable disease.
Researchers at Michigan Medicine found a strong association between lower grip strength and accelerated biological aging in middle-aged and older adults. This study provides evidence that maintaining muscle strength across the lifespan may help protect against age-related diseases.
A new study published in PLOS Medicine found significant long-term morbidity in children, adolescents, and adults after COVID-19 infection. Children and adolescents are at risk of post-COVID-19 syndrome, with rates of malaise, cough, and headache increased compared to controls.
A new study finds that achieving access to minimum resources and services for all while safeguarding the Earth system requires redistribution and societal transformations. The research shows that the wealthiest individuals and societies must undergo transformative change to mitigate climate impacts, while the poor are not the primary c...
Cancer Research UK launches a global consultation for the Cancer Grand Challenges initiative, inviting researchers, patient advocates, and the public to submit ideas for tackling cancer's toughest challenges. The consultation aims to identify select challenges that could revolutionize cancer research, with the goal of shaping funding a...
Researchers discovered that a lipid called prostaglandin E2 weakens lung immune cells with age. This increased PGE2 production impairs alveolar macrophage health and leads to a suppressed immune response, making older people more vulnerable to flu infections.
The University of Barcelona is the world-leading institution in research on liver cirrhosis, with a total of 177 published articles. Professor Pere Ginès has the top world citation index per article, highlighting the institution's scientific performance.
Researchers created a new set of standards, called FAIR, to manage AI models, making them findable, accessible, interoperable and reusable. This standardization enables cross-pollination across teams and reduces duplication of effort, ultimately facilitating scientific discovery.
Scientists identified a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes. The new test reduces the number of individuals who need to undergo oral glucose tolerance testing.
The 2022 AAAS Kavli Science Journalism Awards recognized stories exploring the behavior of small animals at the edge of the visible world and others dealing with world-changing forces of climate change. Winners included journalists in India, China, Australia, South Korea, Germany and the United Kingdom.
A new study published in Collective Intelligence journal suggests that evolutionary forces may be fueling collective tendencies to discriminate. The research recommends fostering environments where desired behavior emerges naturally through evolutionary dynamics rather than regulating against undesired outcomes.
Researchers from the University of Zurich have discovered why a stem cell transplant is effective in treating multiple sclerosis. The study found that memory T cells reappear immediately after the transplant and do not trigger an autoimmune reaction due to pre-damage caused by chemotherapy. This knowledge enables the body to gradually ...
The Tianma 65-m radio telescope helped detect over 600 emission lines in the Orion Kleinmann–Low Nebula, including 21 new species. High-Δn RRLs and complex organic molecules like NH3 were also identified, providing valuable insights into the region's physical and chemical properties.
Researchers estimate food pantry services contribute up to $28 billion nationwide, with households spending $40-$60 per trip and $600-$1,000 per year. The study provides valuable insights into the economic value of food pantries, highlighting their importance in addressing food insecurity.
Researchers used ancient leaf waxes and climate modeling to predict that warmer conditions will lead to stronger and more widespread summer rainfall across the southwest US. This is in contrast to drier subtropical regions experiencing aridity due to global warming.
A randomized clinical trial will examine the efficacy of two supportive programs delivered by telephone and video conference in improving pain, psychological distress, and sleep disturbances in women undergoing surgery. The study aims to address the whole person's mental and behavioral health to optimize surgical outcomes.
A new study finds no significant difference in overall survival or complete remission rates between children and young adults with different levels of poverty exposure, regardless of their neighborhood opportunity. CAR T-cell therapy is equally effective for those from disadvantaged households as it is for those from more socioeconomic...
Employees form relationships naturally aligned with their cognitive style, leading to subpar performance. However, top performers build networks that complement their style, enhancing creative output and execution skills.
A study analyzing seroprevalence data found that global COVID-19 infection rates are likely higher than reported, with 59.2% of the population seropositive as of September 2021. The study suggests that two-thirds of the global population may have antibodies from vaccination or infection.
A new study published in the Strategic Management Journal suggests that employees' opinions of a CEO can influence the board's decision on CEO dismissal. The researchers found that higher employee approval lowers the chances of CEO dismissal by the board, particularly when firm performance is strong and analyst recommendations are posi...
Researchers found that people living with HIV have a significantly delayed internal body clock, consistent with the symptoms of jet lag. This disruption may contribute to increased health problems experienced by those with HIV. The study suggests a strong need for further research on younger people living with HIV in other countries.
A University of Gothenburg study finds that light physical activity can lead to milder symptoms and improved survival rates for patients with intracerebral hemorrhage. The research shows a clear link between physical activity and reduced severe symptoms, as well as higher survival rates compared to those who are less active.
A new study by Mara Buchbinder and colleagues found that physician burnout during the first wave of COVID-19 was influenced by individual, institutional, professional, and societal factors. Interventions to reduce stress and burnout should focus on systems-level changes, including organizational culture and team dynamics.
A new study found that healthier plant-based dietary patterns had lower cardiovascular disease risk and lower greenhouse gas emissions compared to less healthy plant-based diets. Diets high in refined grains, sugary drinks, and processed meat required more cropland, fertilizer, and irrigation water.
A new study found that Chinese incursions into Aksai Chin region are not random, but part of a strategically planned effort to gain control. The researchers believe deterrents could be established in specific areas to defuse tensions along the entire border.
Researchers at the University of Surrey have developed a technology that captures CO2 from the atmosphere and transforms it into useful chemicals. The switchable Dual Function Materials (DFMs) can produce multiple chemicals depending on operating conditions, making it responsive to demand fluctuations.
Global carbon emissions have reached a record high, with no indication of a decline to limit global warming to 1.5°C. The Global Carbon Project projects total global CO2 emissions of 40.6 billion tonnes in 2022, fueled by fossil CO2 emissions that are projected to rise 1.0% compared to 2021.
A new study of 200,000 patients found that those who smoke cigarettes and drink heavily are more likely to experience post-surgical complications. However, talking to a health coach about drinking-related risks before surgery can help patients cut their alcohol use in half and reduce the likelihood of surgical issues.
A new study reveals that households using prepayment meters consume significantly fewer portions of fruit and vegetables compared to those on alternative payment methods. The researchers found a strong link between higher energy bills and lower consumption of essential nutrients, highlighting the 'heat-or-eat' dilemma.
A new study found that smartphones can harbor allergens such as cat and dog dander, β-D glucans, and endotoxin. Cleaning compounds like chlorhexidine/cetylpyridinium chloride and benzyl benzoate/tannic acid were effective in reducing these allergens.
The study found that identity cues accounted for up to 61% of the variation in voting, causing viewers to evaluate content faster. Positive feedback enhanced reputations, while negative cues led to down-votes. Reputations influenced how viewers perceived and engaged with online content.
Researchers found two Korean native plants' saponins inhibit SARS-CoV-2 entry into cells by blocking membrane fusion. These compounds show promise in treating COVID-19, especially for asymptomatic cases.
A new AI-based chemical sensor can accurately detect specific gases in the air by analyzing temperature changes in a microbeam resonator. The device uses machine learning to differentiate between gases with varying thermal conductivities, achieving 100% accuracy in identifying helium, argon, and CO2.
A recent study by the University of Gothenburg and Chalmers University of Technology found that economic factors significantly influence the regulation of hazardous chemicals in Europe. Regulators tend to prioritize chemicals with secondary importance, leading to reduced hazard reductions. The study suggests that current production or ...
Researchers found that oral cancer cells releasing EVs under TGF-β induce EndoMT in endothelial cells, leading to vascular destabilization. This process may facilitate cancer cell entry into the bloodstream, promoting metastasis.
A 5-year follow-up study found patients who received a patient activation training had more primary care use and fewer substance-related emergency department visits. The intervention taught patients to connect with their primary care team, manage their health holistically, and overcome stigma associated with addiction treatment.
A new study reveals that only half of food allergic adult patients have immediate access to epinephrine, and 36% believe EAIs can cause life-threatening effects. The top reported reason for not having an EAI is lack of education on their necessity.
Researchers at Argonne National Laboratory have identified promising new biofuels that can reduce greenhouse gas emissions by up to 60% while improving fuel efficiency or reducing tailpipe emissions. The biofuels, developed using advanced engine design, can be blended with conventional fuels to improve engine performance and meet more ...
A new study found that BRCA1/2 mutation-associated cancers have specific features that contribute to their high risk of recurrence, including changes in the BRCA2 protein's messenger-RNA molecule. The researchers identified multiple novel markers of therapeutic resistance, highlighting the importance of tumor profiling at treatment time.
A global analysis of habitat changes in coastal wetlands has clarified the decline of shorebird populations. Changes in intertidal feeding areas and high tide roosting areas have been identified as critical factors contributing to the decline of non-breeding shorebirds.
A new study by researchers at the University of Nottingham found that our ancient ancestors were more complex than originally thought. This challenges existing evolution theories and suggests that loss of features is a key driver of evolution.
Using 1980s environmental inventories, researchers found that disaster risk assessment could have predicted the damage from the Great East Japan Earthquake. The study compared composite risk maps from the 1980s with post-2011 hazard maps to show a significant increase in high-risk areas.
Researchers at the University of Pittsburgh School of Medicine have discovered a genetic link between melanoma tumors and telomere maintenance, which could lead to new treatments for the disease. The study found that mutations in the TPP1 gene stimulate telomerase activity, promoting long telomeres that enable cancer cells to divide in...
A new CRISPR genome editing treatment has shown promising results in alleviating swelling and reducing the frequency of attacks in hereditary angioedema patients. The treatment, NTLA-2002, targets the KLKB1 gene and reduces kallikrein production, a protein responsible for debilitating swelling attacks.
Researchers induced brain-like sleep in an artificial spiking neural network, enabling it to retain previously learned information. This breakthrough helps the model avoid catastrophic forgetting and improve its overall performance over time.
A recent study of 4.8 million children with otitis media found that socially disadvantaged kids were less likely to receive treatment, increasing their risk of complications and hearing loss. The findings highlight the need for equitable access to ear infection treatment for all children.
A new nanotechnology platform has successfully converted solid tumor cells into immune-activating targets, making them more receptive to immunotherapy. The approach uses a bispecific nanoconjugate to attach an immune-activating molecule to the surface of cancer cells, triggering an immune response.
Ritsumeikan University researchers have developed a soft robotic microfinger that enables direct interaction with insects through tactile sensing. The study shows great promise towards realizing human interactions with the microworld and has applications in augmented reality technology.
A new study found that maintaining universal masking policies in schools significantly reduced COVID-19 cases among students and staff. The study showed that lifting masking requirements led to a substantial increase in cases, highlighting the importance of universal masking in reducing transmission.
Research recognizes significant association between unhealthy behaviors and conditions like obesity, diabetes, smoking, leading to poorer COVID-19 outcomes. Experts emphasize promoting healthy lifestyles to combat syndemics, particularly impacting underserved communities.