A new SERS method using a liquid 3D hotspot matrix enables online quantitative detection of anticancer drugs in serum. The method exhibits 50ppb sensitivity and a range of 50-1000ppb for the drug 5-fluorouracil.
A Mayo Clinic study of 106,349 primary care patients found that hospitalization rates for breakthrough COVID-19 were extremely low, even among those previously infected or vaccinated. The study supports previous findings that vaccination is the best way to prevent severe COVID-19 infection and hospitalization.
Researchers at OIST Graduate University identified the strip1 gene as essential for keeping retinal ganglion cells alive. The gene suppresses Jun-mediated apoptosis, promoting correct neural circuit formation in the retina. This finding opens promising new avenues for treating diseases like glaucoma.
Dr. Xavier Montalban has made significant contributions to understanding multiple sclerosis, improving its diagnosis, and testing ground-breaking therapies. He developed criteria to determine if a disease-modifying therapy is working, informing decisions for switching treatments.
The new NCHRP Guide updates pedestrian analysis methodologies to support safe and sustainable communities. The research team developed new products published in 2022, free to download from the National Academies Press.
A team of researchers discovered that combining food-grade plant extracts like okra and aloe can effectively remove microplastics from wastewater. The most effective combination was found to be okra paired with fenugreek in ocean water, while okra paired with tamarind worked best for freshwater samples.
People with severe mental illness experience increased likelihood of health problems and poorer physical health due to inadequate pain management. Current treatments are often excluded from clinical trials, and low physical activity is a common issue in both conditions.
A new study from Mayo Clinic and Baylor College of Medicine found that targeted genomic information can significantly impact drug prescribing practices. By applying drug-gene testing, clinicians can identify nearly every patient as a potential candidate for preemptive testing, particularly for drugs with unknown genetic influences.
Researchers found that tropical carbon loss has doubled over the past two decades due to excessive forest removal, primarily caused by agricultural expansion. This study highlights the importance of monitoring deforestation trends and the need for effective strategies to reduce forest loss.
Researchers develop novel therapeutic approach for treating tuberculosis using phosphatase inhibitors, offering potential benefits for TB research and basic biology exploration. The discovery provides a promising alternative to traditional antibiotic-based treatments and has significant implications for combating antimicrobial resistance.
Astronomers have identified a nearby Sun-like star that has paused its own cycles and entered a similar period of rare starspots, sparking hope for understanding the Sun's 70-year Maunder Minimum. Continued observation could provide crucial insights into the Sun's stellar magnetic activity, potentially affecting climate on Earth.
A novel system to control protein aggregation in a model of Parkinson’s disease suggests that aggregation of alpha-synuclein plays a critical role in disrupting neuronal homeostasis and triggering neurodegeneration. Light treatment led to formation of Lewy body-like aggregates, neurodegeneration, and Parkinson-like motor deficits in mice.
A recent study of 480 children at risk of neonatal hypoglycemia found no significant association between exposure to hypoglycemia and lower educational achievement at ages 9-10. The researchers analyzed data from treated children, suggesting that early treatment may not have long-term effects on academic performance.
Biomed Valley Discoveries will present four posters on ulixertinib (BVD-523), a first-in-class ERK1/2 inhibitor, at the AACR Annual Meeting 2022. The presentations focus on ulixertinib's potential in combating acquired resistance to the drug and its efficacy in combination with other therapies.
A review article by UT Southwestern researchers highlights the root cause of heart failure with preserved ejection fraction (HFpEF), a condition affecting millions globally. Joint metabolic and immune dysfunction is proposed as the underlying mechanism, opening up possibilities for therapeutic targets.
A Korean research team has developed a radar sensor-based life detection system to help firefighters at indoor disaster sites. The technology can detect victim's biosignals beyond walls using high-precision radar sensors, enabling rapid and safe lifesaving.
A new paper by Adele La Rana details the history of EUROGRAV, a planned array interferometer gravitational wave detector built in Europe in the late 1980s. The project failed due to various reasons, including the fall of the Berlin Wall and economic downturn in the UK.
A booster dose of the Pfizer/BioNTech vaccine significantly increases antibodies against SARS-CoV-2, reversing a drop in immunity after two doses. In subjects given CoronaVac or Oxford-AstraZeneca vaccines, the booster raised immunity by a factor of 25 and 7, respectively.
A University of Alberta study found that environmentally aware consumers are more inclined to buy insect- or algae-fed chicken if provided with information about its health and environmental benefits. Consumers who received nutrition facts on the packaging were more likely to purchase the alternative product, while those without this i...
Researchers at North Carolina State University have developed a way to prevent short-circuiting in yarns designed to store energy by wrapping them with an insulating thread. The findings could advance the development of smart textiles that capture energy from wearer's movements and power sensors.
Researchers developed a new OCT method called Spatio-Temporal Optical Coherence Tomography (STOC-T) to improve the accuracy of eye disease diagnoses. This method uses multimode optical fibers to reduce noise, enabling clearer images of the choroid and other vital parts of the eye.
A new study reveals that ancient Maya people originated from south-to-north migrants carrying maize, which became a staple food. The discovery sheds light on the origins of intensive farming in the Maya region and its impact on the development of large communities.
A study has shown that wind variations over the southern Red Sea are the main drivers of sea-level extremes, driving levels up and down depending on wind direction. This understanding is crucial for coastal planning and management to mitigate the impact of storm surges and coastal erosion.
A recent Cornell University study reveals that white-tailed deer can shed and transmit the COVID-19 virus for up to five days following infection. The virus replicates in the deer's respiratory tract, lymphoid tissues, and central nervous system, making them a potential reservoir for the virus in nature.
Researchers have created a new type of colon tattoo ink that is more biocompatible and less prone to diffusion than existing inks. The ink uses metal-derived nanoparticles and polymers to adhere to the submucosal surface in the colon, allowing for better identification and removal of complex polyps and tumors.
The European Society of Clinical Microbiology and Infectious Diseases finds organ donation from COVID-19 patients is safe and does not transmit SARS-CoV-2. Recipients with asymptomatic infections are also now eligible for transplant, but must be triple-vaccinated.
A new study uses a vast dataset to test the idea that hierarchical structures in human societies arose from cognitive limits on information processing. The research found that for small-scale societies, population size and governing system development influence hierarchy emergence, while medium- and large-scale societies are shaped by ...
A UNIGE team has successfully stored a quantum bit for 20 milliseconds in a crystal-based memory. This achievement marks a major step towards the development of long-distance quantum telecommunications networks.
Teenagers involved in arts activities are less likely to engage in antisocial behaviour up to two years later. They also exhibit better self-control scores and view antisocial behaviour negatively.
Researchers found that vaccine-induced T cells remain stable for up to 15 months after vaccination or infection, recognizing the SARS-CoV-2 spike protein. This long-lasting immune response is crucial in supporting the development of antibodies against the virus.
Scientists from China have developed a bionic approach to improve wind turbine performance by combining features of a seagull's wing with an engineered flow control accessory. The combined flow control improves lift and delays stalling at high angles of attack, increasing the efficiency of wind energy turbines.
Researchers have discovered the opto-ionic effect, where light increases the mobility of ions in ceramic materials, improving the performance of devices such as solid-state electrolytes in fuel cells and lithium-ion batteries. This effect could lead to higher charging speeds and more efficient energy conversion technologies.
Researchers have identified two glucose transporters that disrupt the energy supply to invading worm cells and stop them in their tracks. By deactivating these genes, glucose and ATP levels dropped, and worm cells stalled their spread. This discovery could lead to new ways to cut off cancer cells' fuel lines and prevent metastasis.
A study published in Breastfeeding Medicine found that COVID-19 vaccination was safe for nursing mothers and their breastfed infants, with most symptoms reported being mild. The investigation did not reveal any significant increase in adverse events or complications attributed to the vaccine.
Researchers have successfully created high-quality, crack-free microstructures on silicon surfaces in the ductile regime using elliptical vibration cutting. The technique allows for high-aspect-ratio feature generation with minimal interference, enabling structural coloration and potential applications in displays, sensing, and more.
A POSTECH research team has proposed a novel filterless and electrokinetic-driven ion separation mechanism for lithium and magnesium without the use of extractants. This method enables precise control over ion migration, reducing losses of lithium during extraction from salt lake brines.
A new study suggests that working non-traditional shifts may delay the onset of natural menopause in women. The researchers found a significant association between rotating shifts and later age at menopause, possibly due to disruptions in circadian rhythms. Further investigation is necessary to determine the underlying mechanisms.
The American Association for Cancer Research (AACR) announced its newly elected class of Fellows of the AACR Academy, recognizing distinguished scientists who have propelled innovation and progress against cancer. The 2022 class consists of 33 luminaries from various scientific disciplines.
A new protocol called SPoTKD offers a secure way to transmit data without relying on expensive equipment or dedicated channels. Tiny microchips with self-powered clocks can create secure channels, making it possible for devices to power themselves and stay secure.
The omicron variant's infectiousness period is uncertain, with evidence suggesting it may not be shorter than previous variants. Dr Marjolein Irwin-Knoester recommends a maximum of 7-day isolation for most cases, striking a balance between virus infectivity and community acceptance.
Researchers have identified a novel drug candidate, lonafarnib, that improves neuronal morphological defects, abnormal function, and memory impairments in a mouse model of tuberous sclerosis complex. The study suggests that reducing the levels of active Rheb is crucial for normalizing memory in TSC mice.
Researchers have successfully used a new sound wave technique called burst wave lithotripsy (BWL) to break up kidney stones in humans, achieving a median of 90% stone volume fragmentation within 10 minutes. The procedure shows potential for an office-based treatment approach with minimal tissue injury and no anesthesia required.
Research from Indiana University reveals that cash assistance is a double-edged sword, harming both refugees and local residents if not implemented correctly. Humanitarian organizations can extend cash assistance to host regions with market power by partnering with local governments.
Outbreaks in Hong Kong's high-rise housing have shown vertical transmission of COVID-19 via drainage stack bioaerosols, which can spread through pipes and enhance by poor ventilation. The omicron variant has contributed to the rapid spread.
A systematic review and meta-analysis of 26 studies found music interventions to be associated with clinically meaningful improvements in health-related quality of life. The study suggests that music-making and listening may have a positive impact on overall well-being, particularly for individuals with health conditions.
Researchers report promising results from a phase 3 clinical trial of MDMA-assisted therapy for post-traumatic stress disorder (PTSD), with two-thirds of participants no longer meeting the diagnostic criteria. The therapy showed better effect sizes than selective serotonin reuptake inhibitors (SSRIs) and was equally effective in treatm...
Researchers warn of machine learning bias when data published for one task is used to train algorithms for a different one. This can lead to compromised integrity and 'overly optimistic' results in medical imaging applications.
A new study published in BRAIN shows that a neuronal growth factor called BDNF plays a major role in amplifying spinal cord pain signalling in male humans and male rats, but not in female humans or female rats. This discovery has significant implications for the development of new treatments for chronic pain.
Researchers have developed a gene therapy that restores night vision in dogs with congenital stationary night blindness (CSNB), a condition affecting the ON bipolar cells. The treatment enables dogs to navigate mazes in dim light and has a lasting therapeutic effect, paving the way for potential human treatments.
A study by Jason Hickel reveals that the global North appropriates vast resources and labor from the global South through price differentials in international trade, resulting in a net drain of $10.8 trillion in 2015. This unsustainable practice perpetuates global inequality and ecological breakdown.
Research from the University of Minnesota found that lower left atrial function was associated with higher risk of developing dementia. Atrial myopathy, characterized by abnormal left atrial function and size, was identified as an independent risk factor for dementia.
A team of researchers has discovered a compound called TC-2153 that reduces seizure severity in mice with temporal lobe epilepsy by decreasing the activity of hippocampal neurons. The study found that female sex hormones play a role in the efficacy of TC-2153, which may be relevant to sex differences seen in temporal lobe epilepsy.
Researchers develop a method to leaven pizza dough without yeast by dissolving gas into the dough at high pressure. The team fine-tuned the pressure release rate through rheological analysis to create ideal rise, resulting in light and airy pizzas.
Treatment with an antiplatelet agent had a low likelihood of providing improvement in the number of organ support-free days within 21 days in critically ill COVID-19 patients. The study found no significant benefit from using antiplatelet therapy in this population.
A new study published in Radiology has found that ultrasound images can effectively classify adnexal lesions into classic and non-classic categories, with a sensitivity of 92.5% for diagnosing malignancy. The classic versus non-classic approach could help radiologists quickly assess lesions and avoid unnecessary surgery.
Using a previously published and carefully curated dataset, researchers reconstructed the evolution of protein sequences to build a comprehensive evolutionary tree of beetles. The study provides a refined timescale of beetle evolution, with over 400 thousand species described.
A recent study revealed the importance of Cav3.1-driven burst firing in the ventromedial hypothalamic nuclei in controlling anxiety-like behavior and energy expenditure following chronic stress. Enhanced burst firing was correlated with increased anxiety-like behavior, reduced food intake, and decreased energy expenditure.
A new study suggests that a high-salt diet can lead to the hyperactivity of brain cells, resulting in increased constriction of blood vessels and worsening of cardiometabolic diseases. The research also found that excessive salt consumption can trigger an unusual response in which neurons become more active despite reduced blood flow.
Theoretical physicists have successfully created and observed a synthetic tensor monopole in diamond, inspiring new research on abstract physical structures. The experiment demonstrates the potential of quantum simulators to study complex systems initially introduced in mathematical physics.
A new vaccine platform, using spherical nucleic acid (SNA) nanoparticles, has been shown to produce an immune response in animals and offer protection against lethal doses of the SARS-CoV-2 virus. The results suggest that this approach could be used to target other infectious diseases.
A comprehensive literature review found that consuming plant-based alpha-linolenic acid (ALA) rich in walnuts and flaxseeds can lower cardiovascular disease risk by 10% and fatal coronary heart disease risk by 20%. ALA may also benefit heart health when combined with other omega-3s.
This cross-sectional study investigated the association between adverse childhood experiences and poor neuropsychiatric health in former NFL players. Football-related concussions were found to be significantly associated with increased risk of dementia and poor neuropsychiatric health among these athletes.
Researchers discovered that epilepsy patients' social media activity increased before their sudden deaths from SUDEP. The study found significant alterations in the patients' digital behavior, including changes in the number of words written and drastic sentiment shifts in their posts.
Researchers identified three NAFLD subtypes with unique lipidomic profiles and varying cardiovascular disease risk. Subtype A shows a lower CVD risk profile, differing from other subtypes, which may explain variation in hepatic versus cardiovascular outcomes.
Researchers at the University of Houston have developed a novel technology to monitor membrane protein trafficking in real-time using bioluminescence. This allows for the study of cellular processes and drug development for heart disease, metabolic disorders, cancer, infectious diseases, COVID-19, and others.
Researchers studied Apophis's physical characteristics and possible effects during its 2029 approach. Simulations revealed that low densities could lead to up to 90% of loose stones being removed from the asteroid's surface.
Researchers identified key factors contributing to the gender gap in engineering courses, including female instructors, peer participation, and icebreaker questions. The study suggests that these strategies can help increase women's participation and close the gap in STEM fields.
Researchers from NTU Singapore and Waseda University found that fermented soybean waste improves fat metabolism and mitigates the effects of diet-induced obesity. The study, published in Metabolites, showed that mice fed fermented okara gained less body mass and had lower levels of fat and cholesterol.
A study found that excessive sugar consumption can promote inflammation and autoimmune diseases, such as Crohn's disease and type 1 diabetes. Researchers identified GLUT3, a glucose transporter, as a key player in this process, and proposed blocking its activity to mitigate inflammatory responses.
Roman will explore cosmic acceleration using multiple methods, including spectroscopy and imaging surveys. The mission aims to create a 3D map of the universe by measuring accurate distances and positions of millions of galaxies.
Researchers have developed a new type of coating that can limit the flammability of wood used in construction, potentially providing more time to escape fires and curb their spread. The environmentally friendly flame retardant could also be used for other flammable materials.
Researchers used single cell RNA-sequencing to identify specific cells and genes in maize roots responsible for nitrate uptake. The study provides valuable insights into optimizing root nutrient uptake ability in crops.
A new study by Santa Fe Institute researchers Katrin Schmelz and Samuel Bowles found that people's opposition to vaccines quadrupled when mandated, but many switched to pro-vaccination as they became more convinced of the vaccines' effectiveness. To increase vaccination rates, policymakers need to focus on building trust and changing h...
The new center aims to develop quantitative imaging markers to reduce subjectivity in medical image diagnosis and improve consistency. Researchers will explore cutting-edge imaging modalities and extract effective image features from existing clinical imaging modalities to aid in cancer detection and treatment.
Researchers at the University of Illinois created quantum dots to visualize macrophages in fat tissue, shedding light on chronic inflammation's role in diseases. The new technology enables accurate cell counting and tracking over time, offering a potential diagnostic tool for insulin resistance and metabolic syndrome.
Researchers at Massachusetts General Hospital discovered that non-dividing colon cancer cells employ Warburg glycolysis to reduce toxic reactive oxygen species accumulation. This adaptation challenges the long-held dogma of the Warburg effect, highlighting the need for single-cell level analysis tools.
Scientists have discovered a promising strategy to treat Ebola virus infections by targeting cellular protein GSPT1, which the virus hijacks for polymerase function. An experimental drug CC-90009 degrades GSPT1, halting viral multiplication.
Researchers at Karolinska Institutet identified a novel protein mechanism that inhibits tumour growth in ER-negative breast cancer, leading to improved prognosis. High levels of GIT1 were associated with reduced tumour growth and better outcomes in ER-negative patients.
A new study led by Kelly Monaghan at West Virginia University suggests that interrupting the immune response may improve multiple sclerosis outcomes. The researchers found that targeting a specific protein called CCL17 can prevent the disease from attacking the central nervous system, leading to milder symptoms and delayed paralysis.
Researchers from Hefei Institutes of Physical Science, Chinese Academy of Sciences developed a novel neutron shielding composite called Sm2O3-APTES/AFG-90H. The composite exhibited improved thermal stability, mechanical properties and efficient neutron shielding performance due to the use of coupling agents.
A genome-scale analysis of echinoids reveals modern species emerged 300 million years ago, survived mass extinction, and diversified rapidly. The findings also suggest sand dollars and sea biscuits originated earlier than thought, with possible fossil record gaps.
A new study by Imperial College London found that home pulse oximetry can act as a safety net for COVID-19 patients, reducing unnecessary hospital admissions while spotting early signs of deterioration. The researchers recommend using a defined cutoff point in blood oxygen levels to determine when patients need medical attention.
Researchers from Doshisha University discovered bats perceive spaces through echolocation as a distinct 'echo space', which changes as they become familiar with their environment. The study found that the direction of echoes correlates with bat flight paths and can be used to develop advanced sensors for navigation.
Researchers at Linköping University have discovered that magnesium diboride becomes superconductive at higher temperatures when stretched. The study's findings offer a new approach to increasing critical temperatures without high pressure or complicated structures.
Researchers developed an AI algorithm that can measure coronary plaque buildup in five seconds, predicting heart attack risk within five years. The tool was trained on images from 921 people and matched results with invasive tests considered highly accurate.
A wireless, biodegradable sensor implanted in mice detected dopamine levels and other brain properties, offering potential for real-time monitoring of neural-related conditions. The device is designed to be biodegradable, eliminating the need for future surgeries.
Researchers create transgenic lettuce that expresses a bone-stimulating hormone, which could help prevent osteopenia in astronauts and resource-limited areas on Earth. The lettuce would need to be consumed daily by astronauts to get a sufficient dose of the hormone.
Researchers at University of Illinois discover key connection between symmetry and Mott physics, providing new insight into high-temperature superconductivity. They found that breaking a hidden symmetry destroys Fermi liquids, implying that all models of Mott insulators must break this particle-hole symmetry.
According to a systematic review of over 16 million young people from 25 countries, children with disabilities experience higher rates of violence, including physical, sexual, and emotional abuse. The study highlights the urgent need for collaborative efforts to raise awareness and strengthen prevention efforts.
Researchers at Northwestern University developed an AI-assisted Nanofountain Probe Electroporation system to engineer stem cells. The new method reduces cell loss and increases throughput, enabling selective manipulation of individual cells in micro-arrays.
A clinical trial found that daily cranberry consumption improved flow-mediated dilation, a biomarker of cardiovascular disease risk, in healthy men. Cranberries' unique proanthocyanidins may play an important role in preventing cardiovascular disease.
Scientists at St. Jude Children's Research Hospital identified two genes associated with accelerated aging in childhood cancer survivors. The study used genome-wide association studies to find variants that correlate with epigenetic age acceleration, a measure of the difference between biological and chronological age.
Researchers analyzed the effects of environmental pressure setting, time step, and mesh density on the pressure differential calculation results. The study used numerical simulation to improve the accuracy of calculations, with results showing that changes in ambient pressure are the primary factor affecting the pressure differential.
Researchers at Brown University propose a new model that explains crowd behavior by considering the individual's visual perception. The model accurately predicts actual crowd flow, showing how visible crowd members influence an individual's movement and path.
Researchers at CNIC discover that bone marrow activation is an early event in the development of atherosclerosis, leading to inflammation and plaque formation. The study identifies metabolic syndrome as a key trigger for this process.
Researchers found men with periodontitis who also experience erectile dysfunction are nearly four times more likely to suffer major adverse cardiovascular events. These events can include heart attacks, strokes, and other life-threatening conditions.
Researchers at the University of North Carolina at Chapel Hill have developed a new oral compound that is as effective as molnupiravir in reducing disease in mice, showing promise for treating COVID-19. The pill form of remdesivir could make it accessible for early treatment and reduce hospitalization rates.
A study from the University of Georgia shows that exergaming can increase satisfaction and autonomy in exercise, leading to increased physical activity and motivation. The research followed participants who were randomly assigned to either exergame or traditional aerobics classes for six weeks.
New research from the University of Exeter reveals that people can switch between multiple social identities with ease. The study found that rapidly activating different identities has no apparent difficulty and may even be beneficial for remote workers who struggle to separate their work and personal lives.
Scientists at Georgia Institute of Technology observe unprecedented atomic processes that dictate mechanical behavior in metals. They develop novel methods to visualize grain boundary sliding, revealing previously unknown movements and accommodating transferred atoms through adjusting grain boundary structures.
A new study published in Tobacco Control found that cities banning flavored tobacco sales have reduced youth tobacco use, particularly vaping and cigarette smoking. In contrast to a previous study, the new analysis supports a ban on flavored tobacco products as an effective measure to prevent adolescent tobacco use.
A pilot study by UC San Diego School of Medicine found that eight weeks of mindfulness training significantly reduced symptoms of trauma and depression in individuals grieving from gun violence. Participants showed notable improvements in life satisfaction, with benefits lasting after the program concluded.
Researchers have created a novel sorbent that effectively removes copper and zinc from water solutions, with the ability to be reused for efficient treatment of industrial wastewater and drinking water. The sorbent's adsorption properties were enhanced through modification, allowing for up to 60% removal of heavy metals within minutes.
Scientists developed a pipeline for identifying and prioritising potential tumour antigens for fast generation of cancer vaccines. The 'plug-and-play' vaccine technology enables rapid, affordable, and feasible approaches to deliver targeted peptides to patients, potentially leading to quicker and easier personalized therapy.
Scientists used supercomputers to model plate tectonics and reconstruct dynamics of Pacific plate motion. The study explains the mysterious 60-degree bend in the seamount chain by introducing a new factor: subduction zones in the Russian Far East.
Researchers from IRB Barcelona have discovered that damaged mitochondria accumulation triggers inflammatory processes leading to muscle atrophy. Correcting mitochondrial function through increased BNIP3 levels can mitigate inflammation and muscle loss, offering potential tools for promoting healthy ageing.
Organ donation from dying COVID-19 patients appears to be safe and does not infect recipients with SARS-CoV-2. The study found all 6 abdominal organs had stable graft function and no unexpected rejection occurred.
Researchers at UC Davis have developed genetically modified lettuce producing a drug to protect against bone density loss in microgravity. The transgenic lettuce combines parathyroid hormone with an antibody protein, allowing for stable production and potential self-administration by astronauts.
Researchers at Flinders University have discovered how enterochromaffin cells in the gut communicate with the brain and spinal cord, shedding light on the 'gut-brain axis'. The study reveals that these specialized cells release serotonin into the body, which acts on nerves to communicate with the brain.
Researchers at Brigham and Women's Hospital discovered a tissue-modifying molecule that can target intestinal stem cells and signal them to create Paneth cells, a rare but important cell type. This could represent a new therapeutic pathway for diseases such as inflammatory bowel disease and graft-versus-host disease.
Studies of 54 'good sleepers' revealed that lower slow-wave activity over the right prefrontal cortex is linked to a greater propensity for risk. The findings suggest that targeted interventions could modulate slow waves to influence risk-taking behavior.
The Human Brain Project (HBP) has brought together neuroscientists from different disciplines to work collaboratively on common goals. The HBP researchers outline their scientific approach and illustrate the potential of EBRAINS infrastructure for neuroscience research.
A new study published in JAMA Network Open reveals that the first-pass metabolism of alcohol occurs in the stomach, not the liver. This finding explains why some patients experience increased sensitivity to alcohol after bariatric surgery, leading to higher risks of alcohol-related disorders.
A new study reveals that salt marsh grass in Georgia's coast relies on beneficial bacteria in its roots to access nutrients, improving plant productivity. The research provides insights into the importance of soil microorganisms in maintaining ecosystem health and supporting restoration efforts.
A new study from the University of Illinois suggests that whether adolescents believe drug use is wrong has twice the magnitude of impact compared to other risk and protective factors. This finding highlights the importance of instilling a negative belief about drug use in young people as a key strategy for preventing substance use.
New research from Rutgers University sheds light on the genetic mechanisms of reproductive disorders, including infertility and miscarriage. The study reveals how the RNA helicase YTHDC2 regulates meiosis, a critical step in egg and sperm development.
Home health aides have been serving as lifelines to older adults during COVID-19 pandemic, providing essential medical assistance. Integrating them into healthcare teams could yield significant benefits, improving older adults' health outcomes.
A recent study has found that adolescents are increasingly attempting to quit cigarettes and e-cigarettes, with a notable increase in unsuccessful attempts between 2019 and 2020. The study suggests that these attempts may be linked to an increased risk of nicotine addiction among youth.
A recent study found that US youth who have attempted to quit e-cigarettes and failed saw a significant increase in numbers, reversing a two-decade-long decline in nicotine quit attempts among teens. This reversal is largely attributed to the growing prevalence of adolescent e-cigarette use.
A study by Charité researchers found that fungal pathogens benefit from cooperative relationships, exchanging metabolites and becoming tolerant to anti-fungal drugs. This mechanism also provides growth advantages for metabolically competent cells, reducing their susceptibility to hundreds of antimicrobial substances.
A series of studies on endangered species near the China-Vietnam border highlights the urgent need for coordinated approaches to prevent biodiversity loss. Climate change is expected to significantly impact habitats and species distributions, emphasizing the importance of transboundary conservation measures.
Researchers identified common features of pediatric antiphospholipid syndrome, a rare autoimmune disease causing inflammation and recurring blood clots. Nearly half of children with APS experienced recurrent blood clots despite treatment, highlighting the need for early diagnosis and prevention.
Researchers found that infants and toddlers had significantly higher levels of antibodies against SARS-CoV-2 compared to adults. Children under 4 years old had the highest levels of RBD and neutralizing antibodies, indicating a strong immune response.
Researchers developed a lightweight exoskeleton that uses machine learning to predict user intentions and provide assistance. The system successfully helped participants stand up, demonstrating potential for supporting individuals with mobility impairments.
A new genomic platform has been developed to study the mouse epigenome, allowing researchers to analyze 285,000 epigenetic control points. The system uses microarrays to detect changes in DNA methylation sites and has been validated using archival specimens.
A research team at KAIST developed a method for direct measurement of dielectric tensors in 3D anisotropic structures, overcoming previous limitations. This breakthrough enables the exploration of inaccessible nematic structures and interactions in non-equilibrium dynamics.
Dr. Perla Balbuena's study uses quantum chemical methods to track specific reactions on Li-metal battery surfaces, revealing insights into polymer formation and surface chemistry. The research aims to optimize Li-metal batteries' performance and lifespan by controlling reactivity.
Researchers found that suspected amygdala neurons producing corticotropin-releasing factor are not necessary for alcohol withdrawal or dependence. Instead, the CRF is believed to come from other neurons in the brain, with potential implications for human treatment options.
Research finds that people from different countries and backgrounds prefer original color compositions in paintings, even those they've never seen before. The study suggests a common biological basis for beauty perception, contradicting cultural background and education.