A group of biologists and ethicists suggest adding clarity to ongoing research using embryo models to refine the legal definition of human embryos. They propose a new definition that focuses on what an embryo can become rather than how it came to be, allowing for improved evaluation of models and potential future recognition as embryos.
A new study found that children as young as 4-5 years old can avoid and recognize sick faces, while adults are more accurate. The study's findings add to the growing body of knowledge on humans' sensitivity to illness in faces, suggesting a behavioral immune system that improves with age.
A European gene therapy clinical trial has demonstrated the possibility of restoring expression of the UGT1A1 enzyme in patients with severe Crigler-Najjar syndrome. The treatment resulted in significant reduction in bilirubin levels and sustained efficacy in patients, offering a new hope for treating this rare metabolic disease.
Researchers found that both dietary weight loss strategies improved the diversity of the gut microbiome. The study suggests that individuals can choose a strategy that works for them, regardless of its impact on their microbiome. Changes in the microbiome may also affect other body functions.
A new study published in Nature Genetics has identified over 4,000 genetic variants linked to brain structure, revealing how the brain's organization is shaped by genetics. The research found that different sets of genes contribute to folding and size of the cortex, with some genes linked to larger or smaller head sizes.
Patients with cancer who live in rural Pennsylvania counties are more likely to receive complex surgeries at high-volume hospitals due to their perceived better outcomes. However, for less complex surgeries, rural patients are less likely to opt for high-volume hospitals despite potential benefits from centralization.
A new study links US household income to greenhouse gas emissions, revealing that the top 1% of households generate 40% of total emissions. This income-based carbon tax could incentivize decarbonization and provide revenue for climate finance, addressing emissions inequality.
Researchers successfully simulated super diffusion in a system of interacting quantum particles on a quantum computer, resolving a complex challenge. The breakthrough, achieved using IBM's quantum computer, verifies the Kardar-Parisi-Zhang equation and sheds light on condensed matter physics and materials science.
TDP-43 accumulation in neurons initiates disease progression, spreading to other motor-related neurons. The protein causes mild degeneration in cortical neurons but severe atrophy and cell death in spinal motor neurons.
Researchers have uncovered a living star, HD 45166, that is likely to become a magnetar, marking the discovery of a new type of astronomical object - massive magnetic helium stars. The star has an incredibly strong magnetic field, 43,000 gauss, and will end its life as a compact core with a magnetic field of around 100 trillion gauss.
Researchers developed a new method to estimate vocal cord vibrations pitch from call audio, leading to more accurate dysarthria diagnoses in telemedicine. The method integrates feature quantities extracted from amplitude and phase spectra, demonstrating robustness against background noise.
A study by Cornell University researchers found that current methods for measuring malaria parasite multiplication rates vastly overestimate the actual rates, which has significant implications for vaccine efficacy and understanding of drug resistance.
Researchers found that liraglutide improves associative learning in people with obesity by restoring brain activity to normal-weight levels. The study showed that participants with obesity had reduced ability to associate sensory stimuli and decreased brain activity compared to those with normal weight.
A new study from Lund University in Sweden found that the biggest metabolic changes following gastric bypass surgery occurred immediately after the procedure. However, one year later, the concentration of metabolites and fats had returned to nearly pre-surgery levels.
Researchers have identified a novel pathway to stabilize nanoscale precipitates in alloys by utilizing nonequilibrium processes, stopping coarsening and resulting in stable nanostructures. This approach has potential applications in materials used for nuclear applications, batteries, and other industries.
A new MIT study reveals that soft technology features, such as permitting practices and supply chain management, contribute less than 15% to total cost declines in solar energy systems. Improving these processes could accelerate cost savings in the clean energy transition.
A new study reveals that being divorced is associated with a two-thirds higher risk of lower limb amputation (LLA) in individuals with diabetes compared to those who are married. Additionally, men have a 57% higher risk of LLA than women. The study also found that obesity has a less-than-half the risk of LLA for people with normal weight.
The study found that black soldier fly larvae oil exhibits anti-inflammatory properties, suppressing proinflammatory cytokines and improving colon health. BSFL oil's unique compound profile may offer a new approach to managing inflammatory diseases.
A new study by the PhyloBone project at the University of Turku has identified 255 proteins in 30 species of vertebrates that may play a key role in regulating bone formation and regeneration. The research could lead to new treatments and preventive measures for osteoporosis, a condition that affects millions worldwide.
A new study from Texas A&M University finds a correlation between secondhand smoke exposure and higher blood lead levels in children. The research suggests that education and mitigation efforts can further protect kids and adolescents from lead exposure, building on past success of lead removal initiatives.
A study of a Wolf-Rayet star suggests it will form a magnetar upon explosion as a supernova, with strong magnetic fields predicted. The findings provide new insights into magnetar origins and suggest a possible pathway for their formation.
Researchers detected distinct 'dwarf pulses' from PSR B2111+46 using the Five-hundred-meter Aperture Spherical radio Telescope. These narrow, weak pulses exhibit a rare reversed spectrum and are produced by one or a few particles generated by pair production in a fragile gap of the pulsar's magnetosphere.
A new study found that individuals exposed to common cold-causing coronaviruses have immune responses that may protect them from future SARS-CoV-2 infections. Researchers hope this insight will inform global infectious disease outbreak preparedness and vaccine development.
A new article by leading researchers emphasizes the need for a coordinated approach among all stakeholders to improve trust in research. The authors outline roles for each group, from funders to media outlets, to work together to fortify science integrity.
Researchers developed a new method to assess immune responses to specific antigens after mRNA SARS-CoV-2 vaccine administration, using B cell receptor repertoire analysis. This approach enables evaluation of post-vaccination responses in immunocompromised patients with high antibody titers.
The invasive orange pore fungus has won the third BMC Ecology and Evolution image competition, highlighting its potential threats to Australian ecosystems. The winning image depicts bright orange fruiting bodies growing on deadwood in the Australian rainforest.
Researchers found that natural forgetting can be reversed in certain circumstances, with memories stored in engram cells still intact but inaccessible. Competition between engrams affects recall, and forgotten memory traces can be reactivated by cues or updated with new information.
Researchers at NUS have developed an aero-elastic pressure sensor called eAir, promising increased precision and reliability in medical applications. The sensor can provide tactile feedback for surgeons during minimally-invasive surgeries, enhancing patient recovery and prognosis.
A new study finds that US property values exposed to wildfires and tree mortality will increase sharply in future climate scenarios, particularly in the western US. Aggressive climate action can substantially reduce exposure, with the value of exposed property topping out at $11 billion under mitigation scenarios.
A study found low primary care vision testing rates for children and adolescents, with lower rates among those without private insurance. Despite yearly testing recommendations, less than half of those with private insurance received testing.
A Penn State-led research team discovered that somatostatin signaling acts to dampen communication among cell types in the prefrontal cortex, promoting exploratory and risk-taking-like behavior. The findings suggest that somatostatin fine-tunes circuits to promote certain behaviors, including decision making.
Researchers have made a groundbreaking finding on the role of biofilm formation in hydrocarbon consumption by Alcanivorax borkumensis bacteria. The study reveals that dendritic biofilms alter the oil-water interfacial tension and buckle the oil droplets, optimizing consumption and accelerating biodegradation.
A recent study found that activating astrocytes in the basal forebrain can keep mice awake for hours without affecting their sleep need or intensity. The researchers hope to develop interventions targeting these cells to improve productivity and health of shift workers and others who work long hours.
Environmental regulators should use scientific experimentation to inform natural resource policy, according to an international group of economists. By conducting experiments and analyzing results, policymakers can create more effective programs and reduce uncertainty about what works and what doesn't.
Researchers discovered a new type of astronomical object - a massive magnetic helium star that may evolve into a magnetar. The star has a phenomenally powerful magnetic field, about 43,000 gauss, and will eventually collapse into a neutron star with an even stronger magnetic field.
A new study found that high-stress caregivers had higher klotho levels and longer telomeres in specific immune cells, which may provide protection against aging. In contrast, low-stress caregivers showed no significant associations between klotho levels and telomere length.
A study by Ohio State University found that urban coyote cortisol levels are higher than those in suburban or natural areas. Chronic stress is also linked to poor physical condition, such as mange infection, and the responsibility of running a pack, with alpha individuals experiencing high stress levels.
Chikungunya virus has found a way to evade the immune system by hijacking host cells' cytoskeleton, allowing it to spread directly from cell to cell. This discovery could lead to the development of effective vaccines or treatments for this debilitating mosquito-borne disease.
Researchers have finally found Pines' demon, a massless and neutral composite particle predicted to exist in certain metals. They used a nonstandard experimental technique that directly excites a material's electronic modes, allowing them to see the demon's signature in strontium ruthenate.
A team of researchers identified neural dynamics that our visual system uses to transform what we see into what we do, demonstrating that working memory relies on both what one is storing and why. This new understanding challenges traditional theories of working memory, which state that storage codes are stable over time.
Researchers analyzed thousands of samples from 700 children between birth and 12 years old, finding that racial and ethnic differences in the gut microbiome arise after three months of age. The study suggests that external factors shape these variations rather than being present at birth.
The five-year grant will help create a multinational research partnership to gather data on prevention and treatment strategies for cancers caused by HPV and Epstein-Barr viruses among this population. Cancer is the leading cause of death among people living with HIV, with poorer treatment outcomes.
Researchers developed a new mathematical model to study circadian rhythm resilience and develop ways to improve it in individuals with weak internal clocks. Sustained disruptions can lead to disorders like diabetes and memory loss.
A new study published in JPRAS Open found that breast size affects women's attitudes towards exercise, with larger breasts leading to less frequent exercise. However, after breast reduction surgery, women reported increased overall frequency, enjoyment and willingness to exercise in a group.
Scientists explore ultracold quantum gas to understand wave turbulence, discovering a universal relation that describes the state's characteristics regardless of external factors. The findings echo the universality of the ideal gas law for equilibrium states, opening up new avenues for understanding non-equilibrium systems.
A new study from the University of Nottingham models how antibiotic resistance genes build up in gut bacteria through lifetime exposure to food intake and antibiotic treatment. The research suggests that reducing exposure to resistance genes is particularly effective during periods of antibiotic treatment, and that dietary advice shoul...
Researchers expand simple view of reading framework using meta-analytic structural equation modeling, validating its effectiveness for SFL learners. Decoding skills and language comprehension skills are identified as primary components for effective SFL reading instruction.
Scientists have identified a molecule that regulates nerve cell sensors, which could lead to new therapeutics for obesity, osteoporosis, and inflammatory diseases. The molecule can be modified into peptide-based therapeutics to boost the activity of channels involved in bone strength and satiety.
Researchers found that certain immune cells were associated with increased protection from flu symptoms, while others were linked to susceptibility. The study's findings have implications for developing tailored vaccine platforms and improving public health strategies.
A new study found that the apex predator Saurosuchus had a weaker bite force than previously thought, equivalent to modern gharials. This suggests that it may have fed only on soft flesh and not been able to crush bones, unlike later dinosaurs.
UC Santa Barbara researchers develop new catalytic process that can convert polyolefins from single-use plastics into valuable alkylaromatics, underlying surfactants in detergents. The improved method reduces production time and energy input, enabling potential commercialization and large-scale use.
Researchers from HKUMed and CityU have generated human neural stem cells with enhanced therapeutic potential for treating spinal cord injuries. The new findings, published in Advanced Science, show that reducing the expression of the SOX9 gene promotes motor neuron formation and improves survival and integration of the stem cells.
Scientists have identified platelet factor 4 (PF4) as a common messenger for the cognitive benefits of young blood transfusion, exercise, and the longevity hormone klotho. Studies show that PF4 calms down the aged immune system, reducing inflammation and promoting brain plasticity and cognition.
A study by the University of Konstanz found that people's self-assessments of their immune response to vaccination corresponded surprisingly well with actual antibody levels, especially when the immune response was weak. The researchers suggest that patients' self-perceptions provide valuable clues about their state of health, and phys...
Researchers at the University of Malta discovered that COVID-19 causes long-term muscle weakness by depleting the ACE2 receptor. This finding paves the way for therapeutic approaches to mitigate chronically disabling complications. The study used fruit flies to curb down ACE2 levels, inducing fatigue and diminished mobility.
Researchers at the University of Pennsylvania School of Engineering and Applied Science have discovered dozens of small protein sequences with antibiotic qualities in extinct organisms like Neanderthals and Denisovans. They then synthesized these molecules using artificial intelligence and tested their efficacy against pathogens.
Researchers found stable antibodies in 800-year-old medieval human teeth that can still recognize viral proteins, allowing them to study the history of infectious human diseases. This discovery expands the field of palaeoproteomics and may enable experts to analyze how human antibody responses developed over time.
Researchers at Martin-Luther-Universität Halle-Wittenberg have developed a new method for detecting SARS-CoV-2 using MALDI-TOF mass spectrometry, which takes just two hours from swab to result. The approach can also detect other pathogens and is more flexible than existing PCR tests.
A new study published in the Journal of the American Heart Association found that people who experience pain after a heart attack are more likely to die within the next 8.5 years. The study analyzed data from over 18,300 adults who had a heart attack and found that moderate or extreme pain was linked to a higher mortality risk.
A study by Hebrew University researchers found that directly involved war veterans exhibited almost double the level of PTSD symptoms compared to indirectly active veterans. Parents of active veterans experienced heightened secondary traumatic stress, with mothers bearing a greater burden than fathers.