A study of Australian surveys found that doctors are more extroverted, agreeable, and conscientious than their patients, but also more neurotic. These differences may affect the quality of care and patient outcomes.
Researchers developed a bioengineered drug candidate that counteracts <em>Staphylococcus aureus</em> infections, including MRSA. The mAbtyrins treatment targets multiple disease-causing mechanisms without killing the bacteria.
Researchers discovered that parvalbumin interneurons secrete substance P, driving slow vasodilation and increasing blood flow in the brain. This process allows for waste removal and prevention of neurological dysfunctions like dementia.
A new study reveals an association between poor air quality in India and impaired cognition in infants under two. The study found that air quality was poorer in homes that used solid cooking materials like cow dung cake, and that reducing cooking emissions could have benefits to infants' emerging cognitive abilities.
Scientists at Hefei Institutes of Physical Science proposed a facile method to design efficient biomimetic catalysts using mechanical induced spin transition. The results show that the mixed-spin nanosheet catalyst exhibits high CO yield and selectivity, outperforming its high-spin counterpart.
A recent study published in JAMA Pediatrics reveals that individuals born preterm or large for gestational age have a significantly increased risk of developing atrial fibrillation up to middle-age. In contrast, those born small for gestational age only show an increased risk up to the age of 18.
Researchers developed defect-rich MnOx nanobelts through laser irradiation, improving catalytic activity and substrate affinity. The nanozymes exhibit excellent oxidase mimic activity for detecting glutathione with high sensitivity.
A study using multiple-model GWAS identified optimal allelic combinations of quantitative trait loci for higher malic acid content in tomatoes. The researchers deciphered the polygenic architecture of malic acid content and provided new genetic insights into its evolution during breeding.
A new study published in JAMA Network Open found that intensive blood pressure treatment significantly reduces the risk of adverse cerebrovascular events such as stroke. Participants with hypertension who received intensive treatment showed reduced white matter lesions and improved blood flow, indicating better overall brain health.
A new study by Boston University School of Medicine found that non-Hispanic Black, Asian, and Hispanic women, as well as those with low literacy, experience increased anxiety and confusion when receiving breast density information. These groups are also less likely to feel informed about their breast cancer risk.
Research on 28 male chimps found that certain personality traits like dominance and low conscientiousness are linked to high rank and reproductive success. The study suggests that the best personality for males varies depending on environmental or social conditions, rather than being a fixed trait.
Using non-fungible tokens (NFTs) as a potential data management solution can bridge the gap in privacy-preserving solutions, allowing patients to own their health data and share it securely. This empowers them to engage in their health journey more proactively, resulting in better healthcare outcomes.
Researchers developed a new neural network, MSUN, that accurately classifies plant diseases in natural settings using transfer learning and unsupervised domain adaptation. The model excelled in processing complex datasets and outperformed current crop of classifiers.
A new University of Illinois study suggests that widespread planting of cereal rye could significantly reduce nitrate levels in Illinois' tile drainage water. The research found that adopting winter cover crops, such as cereal rye, can help minimize nitrogen loss and improve water quality.
A team of researchers at Binghamton University partnered with Brookhaven National Laboratory to investigate copper oxide peroxides and their effects on oxidation reactions. They used two spectroscopy methods to observe changes in the surface of copper oxide and found that peroxides enhance H2 oxidation but inhibit CO oxidation.
Researchers reconstructed the full state of a quantum liquid using ultracold atoms, offering insights into quantum systems' fluctuations and behavior. This breakthrough has promise for quantum computing, sensing technology, and better characterization of quantum systems.
A novel cell signaling pathway has been identified that could be targeted to treat aggressive pancreatic cancers. The High Mobility Group A1 (HMGA1) protein functions as a 'molecular switch' that activates genes required for tumor growth and invasion. Silencing HMGA1 or disrupting FGF19 signals in mouse models resulted in decreased tum...
A groundbreaking study published in Nature Neuroscience shows that monkeys can think deeply about problems, consider multiple factors, and find optimal outcomes. This discovery challenges traditional views on animal intelligence and highlights the complexity of monkey cognition.
Researchers at the University of Bristol used NASA's InSight lander data to detect seismic waves traveling into Mars' core, revealing a denser and smaller core comprising iron and numerous other elements. The study found that the core's composition is distinct from Earth's, with a high fraction of light elements alloyed with iron.
Research suggests that patients with advanced melanoma who receive immunotherapy medications may benefit from maintaining normal vitamin D levels. The study found a favorable response rate in 56% of patients with normal baseline vitamin D levels, compared to 36% with low levels.
Researchers identified an ancient mechanism for wound repair, triggered by low oxygen levels and IL24 protein. This pathway coordinates tissue repair without the need for infection, and may be involved in other organs featuring epithelial layers.
The Hastings Center's new report provides direction for research and communications in social and behavioral genomics, highlighting both potential benefits and significant risks. The report recommends engaging with stakeholders, justifying population definitions and phenotype measurement, and conducting studies with adequate power.
Researchers have detected the elusive dimeric product ROOR generated by the self-reaction of ethyl peroxy radicals. The discovery sheds new light on atmospheric chemistry and the degradation of VOCs.
A nationally representative sample of community-dwelling adults found that stroke prevalence remained stable overall, but increased among men. The study's estimates underestimate the total burden due to institutional settings not included in National Health and Nutrition Examination Surveys.
Organic solar cells fabricated with tin oxide exhibit high performance, surpassing current records. The design involves a conductive layer of tin oxide grown via atomic layer deposition, improving device stability and efficiency.
A multicenter international study found that medical management is a viable alternative to surgery for patients with pituitary apoplexy. The study compared outcomes in 97 patients with the condition and found no significant difference between surgical and nonsurgical treatment options.
A novel gel has cured 100% of mice with aggressive brain cancer, a breakthrough that could lead to new treatments for glioblastoma. The gel combines an anticancer drug and antibody to target tumor cells and stimulate the immune system.
Researchers have created a portable device using microfluidic chips and smartphones to detect pathogens in real-time. The device, called Mkit, uses chitosan-modified minimalistic microfluidic chip technology to amplify nucleic acid enrichment, reducing the need for complex cleaning processes.
Targeting a specific antiviral pathway may one day offer a new way to treat or delay cognitive decline in Alzheimer's and frontotemporal dementia. Researchers found that inhibiting a key enzyme called cGAS can help neurons become resilient to tau protein buildup, a hallmark of these diseases.
Researcher Brian Clark presents findings on the role of the nervous system in age-related muscle weakness, exploring potential therapeutic targets such as exercise and physical therapy. His work identifies neural mechanisms linked to low nerve cell excitability, impaired signal transmission, and reduced motor network integrity.
Researchers trained a machine learning program using data from over 5 million direct messages, annotated by 150 adolescents who experienced uncomfortable or unsafe conversations. The technology can quickly flag risky DMs and is intended to address rising trends of child sexual exploitation.
A new phenotyping approach analyzes crop traits at the 3D level using a rail-based field phenotyping platform with LiDAR and an RGB camera. The method provides accurate quantification of crop traits such as plant height, leaf shape, and leaf color.
A new study from Oregon State University found that massive iceberg discharges during the last ice age triggered rapid warming in Antarctica but had no effect on temperatures in Greenland. This discovery challenges current understanding of global climate dynamics and raises more questions than answers.
Researchers have elucidated the mechanism of CELSR cadherin dimerization, revealing a twisted cell-cell adhesion molecule complex structure. The extracellular domains of CELSR cadherins exhibited strand- and globule-like portions, which bound through strand-like structures in an antiparallel orientation.
A new study reveals that Indian farmers have adapted to climate change by changing management practices and using hardier crop varieties. However, the impact of climate change on crop yields varies across crops and regions, with some areas experiencing greater benefits than others.
Researchers at EPFL have developed a novel imaging technique using cryogenic transmission electron tomography and deep learning to visualize the nanostructure of platinum catalyst layers in fuel cells. This breakthrough reveals the heterogenous thickness of ionomer, a crucial component that influences catalyst performance.
A study published in BMJ Open suggests that young children with common ENT issues may be at increased risk of autism or high levels of autistic traits. Early detection and treatment of these conditions could improve their quality of life and potentially shed light on the origins of autism.
Researchers develop self-propelled 'BeerBots' that ferment sugar faster than traditional yeast cells, reducing fermentation time and making separation of yeast from beer easier. The BeerBots were found to be active for up to three more brewing cycles after the initial fermentation process.
A Brazilian study analyzed data from over 40,000 patients admitted to ICUs and found lower mortality rates during the Omicron outbreak compared to previous strains of Covid-19. Vaccination coverage contributed to the lower mortality observed in the Omicron period, but vulnerable patients remain at risk.
Researchers at Hefei Institutes of Physical Science discovered that monolayer hexagonal boron nitride can block electron tunneling, extending the ultimate plasmonic enhancement limit. This breakthrough enables potential novel applications in quantum plasmonics, providing insights into quantum mechanical effects.
Researchers studying the mudskipper, a fish that spends time on land, found that its blinking behavior serves similar functions as in humans and other tetrapods. The study suggests that blinking may have evolved as part of the suite of traits that allowed early tetrapods to adapt to life on land.
Researchers have made an important human discovery by analyzing the genome of a 3,000-year-old individual found in a cave in Southeast Alaska. The study confirms that some modern Alaska Natives still live almost exactly where their ancestors did over 3,000 years ago.
Researchers have created a new method for fast miRNA amplification and detection that reduces the time required to detect micro-RNAs. The technique combines rolling circle amplification (RCA) with CRISPR-Cas12a, resulting in improved sensitivity and specificity, and can be completed in just 70 minutes.
Researchers from Hefei Institutes of Physical Science established the first electronic phase diagram for Fe-intercalated Weyl semimetal Td-MoTe2, exhibiting exotic electronic behaviors and magnetic states. The study enriched the physical properties of Td-MoTe2 by 3D-element intercalation.
A new machine-learning method analyzes metabolites in blood to predict the time of an individual's internal circadian timing system. This approach has shown accuracy comparable to previous methods, but requires fewer samples.
Scientists used SHMFF to study 2D amorphous carbon, revealing its atomic structure and electrical properties. The research demonstrates the complexity of disorder in amorphous materials, providing new ideas for two-dimensional materials and applications.
Kamaljeet Sanghera has received funding to design a summer program for high school students to learn about AI development and its ethical impact. The pilot project will utilize IBM AI kits to provide hands-on experience and technical skills training.
The review summarizes the recent progress of Li-eN2 RR, covering reaction mechanisms, catalysts developed, and electrolytes involved. It highlights the challenges and possible resolving strategies in the field. The study also discusses the importance of rational design of electrocatalysts and electrolytes for efficient NH3 production.
A new analysis reveals that protecting large trees in old-growth forests can sequester significant amounts of carbon and promote biodiversity. The study concludes that policy initiatives aligning conservation with climate change mitigation priorities are crucial for preserving these natural carbon sinks.
A machine learning framework predicts and quantifies chromosome synthesis difficulties, providing guidance for optimizing design and synthesis processes. The model achieved high accuracy and predictive ability, enabling the development of a Synthesis difficulty Index to explain causes of synthesis difficulties.
A study of 167,000 non-hospitalized patients revealed that neutralizing monoclonal antibody treatment for COVID-19 was associated with significant reductions in emergency department visits, hospitalization rates, and mortality. These findings suggest targeted risk stratification strategies may optimize future nMAb treatment decisions.
A new observational study by Vanderbilt University Medical Center researchers has found that early RSV infection is associated with a significantly increased risk of childhood asthma. The study found that infants who weren't infected with RSV in the first year of life had a 26% lower risk of developing childhood asthma at age 5.
A team of researchers developed a rapid in situ detection system for carbaryl residues, enabling sensitive and immediate detection with a low detection limit of 16.3 nM. The system utilizes a combination of silicon quantum dots, gold nanoparticles, and cadmium telluride quantum dots, allowing for portable and practical field testing.
The US military medical system is not ready to handle major conflicts with near-peer adversaries, who possess similar military capabilities. Prolonged field care training and strong patient data are crucial to address the challenges of evacuating wounded soldiers and providing specialized surgical care.
A study reveals that birds in multispecies flocks from Southeast Asia converge on similar appearances, blurring species distinctions. This phenomenon may contribute to diversity by allowing birds to adapt and evolve distinct traits within a species.
This study found that iron deficiency impairs neural differentiation, leading to reduced Pax6- and Sox2-positive neuronal precursor cells and Tuj1 fibers. Iron supplementation restores normal differentiation, suggesting ferrodifferentiation as a new therapeutic approach for neurological diseases.
A team of researchers at North Carolina State University has created a zinc-ion battery prototype with a fiber-shaped cathode, which can power a wrist watch. The team used graphene oxide and manganese dioxide materials to create a yarn-shaped battery that is strong, flexible, and electrically conductive.
Research suggests that problems with the brain's ability to 'prune' itself of unnecessary connections may underlie a wide range of mental health disorders that begin during adolescence. Adolescents experiencing mental health problems showed similar patterns of brain activity, which were largely apparent in the frontal lobes.
New research found that temperature and original viral concentration affect the persistence of Omicron variants on shipping materials. The study reveals that lower temperatures and higher viral concentrations increase stability, while room temperature poses a risk. Safety protocols for shipping goods can be improved with this knowledge.
Researchers develop PrimeRoot, a tool for efficient and precise targeted insertion of large DNA segments in plants, achieving efficiencies up to 6% and inserting segments up to 11.1 kb.