A Danish study found that 7% of seized products contained no active pharmaceutical ingredient, while 22% had inconsistent content. The researchers warn that users may be injecting themselves with cooking oil or other substances instead of intended medications.
Researchers at MIT have created a vaccine printer that can produce hundreds of vaccine doses in a day, using microneedle patches that can be stored long-term at room temperature. The printer can be deployed anywhere vaccines are needed, providing on-demand vaccine production.
A recent study found that nearly 80% of maternal and neonatal healthcare workers experienced a heavy workload during the pandemic, with 18% exceeding the clinical threshold for burnout. Women and young staff were particularly vulnerable to stress and exhaustion.
A custom SNP array containing over 56,606 genetic markers has been created to help breeders select high-quality rice varieties. The Rice3K56 chip demonstrated impressive accuracy in identifying relevant genome and provided more genetic variability information than other previously developed arrays.
A growing number of states have implemented policies to cover outpatient hemodialysis for undocumented immigrants with kidney failure. This expansion may be due to increased awareness of poor outcomes with emergency hemodialysis and advocacy efforts. The move towards covering dialysis in all 50 states is called for by experts, who also...
Researchers at Lund University studied green algae in Swedish lakes to understand how multicellularity evolved. They found that multicellular groups form as a by-product of single-celled strategies to reduce environmental stress, challenging the idea that multicellularity is inherently beneficial.
Research team used genome models to test viability, persistence, and evolvability of prokaryote endosymbioses, finding that more than half were viable but often less fit and adaptable than their ancestors. The study suggests metabolic network compatibility is unlikely the limiting factor in prokaryotic endosymbiosis.
Astronomers have confirmed a protocluster of seven galaxies at a distance of 650 million years after the Big Bang, which will grow into a massive galaxy cluster resembling the Coma Cluster. The James Webb Space Telescope's spectrographic data revealed high velocities and dark matter halo characteristics.
A new study by Dartmouth College researchers found that biased prior beliefs played a significant role in how people from both political parties updated their fraud beliefs after the 2020 U.S. presidential election. The study used a probability-based computational model to analyze survey data and found that Democrats and Republicans te...
A recent study by the University of Surrey found that group cyclists can reduce their exposure to vehicle pollutants by spreading out, especially in busier roads. The research highlights the importance of considering wind movement and positioning within a group to minimize exposure.
A University of Gothenburg study found that future doctors and nurses in Sweden consider their disaster medicine knowledge inadequate. Students who have been conscripts or have experience in rescue services scored higher on a self-assessment questionnaire, suggesting 40 hours of education is reasonably adequate.
A new study reveals that health surveys and clinical studies often exclude transgender and gender-diverse individuals due to the way they record sex or gender. This exclusion can lead to reduced accuracy and inclusivity in study results, resulting in increased health disparities and limited access to healthcare for these communities.
A team of researchers studied mudskippers to understand the evolution of blinking, a crucial behavior for eye health and communication. They found that blinking emerged as an adaptation to life on land, with three main functions: wetting, cleaning, and protecting the eye.
Researchers found that necroptosis promotes metastasis in breast cancer models, and blocking it leads to inhibition of metastasis. Necroptosis may be a key factor in tumor progression, and targeting its regulators could be critical for mitigating metastasis.
Researchers have recovered old weather records from the 1903 Storm Ulysses, revealing it was one of the strongest storms in British history. The digital data analysis shows that similar storms would be rare today, highlighting the risks and potential damage they could cause.
Researchers have identified a new human RNA ligase protein that plays a protective role against cellular stress and oxidative damage. The enzyme, C12orf29, links the ends of RNA strands in three characteristic steps and protects cells from menadione-induced oxidative stress.
Researchers have found a material, palladium, that is optimally suited for creating superconductors with high transition temperatures. This discovery has the potential to revolutionize electricity generation and transportation by enabling materials to conduct electricity without loss at normal room temperature and atmospheric pressure.
MdNAC1 significantly promotes anthocyanin accumulation, enhancing its transcriptional activation through interaction with MdbZIP23. ABA induction further enhances MdNAC1's ability to promote anthocyanin synthesis in red-fleshed apples.
A study published in Scientific Reports found that rats exposed to high-fat diets during pregnancy and early life developed a preference for salty taste. This preference was linked to increased levels of AT1 protein in the taste buds, which can lead to higher sodium intake and potentially contribute to obesity and diet-linked diseases.
A portable electrochemical sensor has been developed for lead ion detection using cobalt-doped Prussian blue combined with MXene material. The sensor exhibits a linear detection range of 1-200 nM, ultra-low detection limit of 0.97 nM and high accuracy in detecting lead ions in different water samples.
Researchers found high sympathetic activation while working, regardless of deadlines, but factors like smartphone use and reading/writing can exacerbate this. The study revealed that researchers instinctively adjust break frequency to regulate stress, providing fresh insights into their behaviors.
Researchers at Ohio State University found that students who participated in one school sport and one other non-sport extracurricular activity were more likely to attend college and attend more selective colleges. Participating in two or more extracurricular activities gave no advantage over taking part in just one.
Researchers found deaths from gallstone disease increased in younger populations and those with Medicaid after Medicaid expansion, highlighting the need for proactive prevention over reactive emergency care. A new healthcare model emphasizing primary care and prevention is proposed to address these inequities.
A new study has found that combining genetic and environmental risk assessment can improve the accuracy of stroke risk prediction. The research used a stroke PRS for East Asian populations and found that individuals with high PRS values were at higher risk of stroke, even among those with intermediate clinical risk profiles.
A landmark Malawian trial has found a single iron infusion can significantly reduce iron deficiency in pregnant women, compared to daily tablets. The treatment, Ferric carboxymaltose (FCM), reduced iron deficiency by around 60% and showed promise for addressing anaemia in resource-poor nations.
A team of researchers from China created universal critical nitrogen dilution curves for 10 Japonica rice cultivars using machine learning methods. The study found that parameters a and b vary with cultivar, year, site, and N fertilizer quantity and ratio. Three universal N C curves were obtained using different approaches, which accur...
The COVID-19 pandemic had a profound effect on healthcare services utilization in mainland China, with a 32% reduction in hospital visits and a negative impact on bed utilization rates two years later. Regional differences were observed, highlighting the need for targeted primary healthcare services and resilient health systems.
A team of researchers conducted simulated whale fall experiments using cow carcasses in the South China Sea, revealing a strong dissimilarity between whale fall communities at different ocean depths. The study highlights the importance of whale falls as unique biodiversity hotspots for sustaining deep-sea life.
Researchers developed a method to convert eggshells into amorphous calcium phosphate particles, which were found to be safe, cell-friendly, and effective in promoting bone regeneration. The findings promise to create an eco-friendly alternative to commercialized xenograft materials.
Researchers found a genetic variant of TNFAIP3, which regulates inflammation, can paradoxically protect the kidneys from damage in the short term. The study could lead to simple genetic tests for predicting kidney disease risk and personalized treatment approaches.
A new study by Uppsala University and hospital reveals a link between neurodevelopmental disorders and an increased risk of testicular cancer, specifically seminoma. The study found that men with these conditions are more likely to develop cancer at a younger age and may have advanced disease at diagnosis.
The study measures digital transformation of Chinese commercial banks using an index system, finding a significant increase in digital transformation from 2010 to 2018. Digital transformation enhances profitability, bank efficiency, and reduces competitive pressure, enabling banks to gain a competitive advantage in the digital era.
A team of researchers at Bar-Ilan University has improved the basic computation unit of quantum computers by developing a tunable superconducting flux qubit. This innovation enables quantum computers to operate with hundreds of qubits simultaneously, leading to significant advancements in computational power and potential applications.
Researchers discovered that autophagy plays a crucial role in facilitating the co-transmission of two distinct arboviruses by insect vectors. The study found that RSMV nucleoprotein activates complete anti-viral autophagy, while RGDV nonstructural protein Pns11 induces incomplete autophagy to promote viral propagation.
A major international trial concludes that surgeons should replace the removed skull section after treating a brain bleed, saving patients from further complications. The study found no significant difference in disability-related and quality-of-life outcomes between the two approaches.
Research has shown that MOFs can enhance electrocatalytic performance by regulating the energy of reaction intermediates and adsorption strength. Strategies to design stable and conductive MOFs are crucial for commercialization.
The researchers proposed a type of ultra-tunable bistable structure with programmable energy barriers and trigger forces. The structures can be customized for various robotic applications, demonstrating superior performances in high-speed locomotion, adaptive sensing, and fast grasping.
A new study uses social media data to understand global air conditioning adoption patterns. It finds that middle-aged, educated males and parents of small children tend to express higher online interest in AC. This research aims to improve climate change adaptation measures by identifying sociodemographic groups at risk.
Researchers developed a novel gene deletion method called SLICER, allowing seamless modification of Deinococcus radiodurans. The technique enables the efficient deletion of multiple genes, potentially leading to improved strains with various applications.
Scientists have successfully engineered multi-layered nanostructures of transition metal dichalcogenides to form junctions, enabling the creation of tunnel field-effect transistors (TFETs) with ultra-low power consumption. The method is scalable over large areas, making it suitable for implementation in modern electronics.
A study found that biological age in humans and mice increases rapidly in response to diverse forms of stress, only to reverse after recovery. The researchers used DNA methylation clocks to measure changes in biological age, revealing transient changes in response to stressful stimuli.
A Scripps Research team found that both alcohol intake and withdrawal can lead to increased pain sensitivity in adult mice. The study suggests potential new drug targets for treating alcohol-associated chronic pain and hypersensitivity.
A large-scale registry study in Finland identified factors associated with COVID-19 vaccination uptake, including low labor income and mental health issues. The study found that individuals in vulnerable positions were the least likely to vaccinate, highlighting the need for targeted vaccination campaigns.
Scientists have successfully mapped the landscape of m6A modification in mouse embryos, revealing intriguing patterns of gene activity and distribution in transposable elements. This study fills a gap in the transcriptome field, providing new insights into the function of m6A during development.
New research using social media advertising data provides insights into the adoption of air conditioning units worldwide, particularly in heat-vulnerable regions. The study found that middle-aged, highly educated, married males, and parents with small children are more likely to express online interest in AC units.
The study highlights the importance of language documentation and revitalization to preserve human communication, culture, and cognition. Grambank reveals that language loss is occurring unevenly across major linguistic regions, with indigenous languages in northeast South America, Alaska, and northern Australia at highest risk.
A study by Carnegie Mellon University found that ridesharing platforms significantly outperformed traditional taxi systems during urban emergencies. The platforms' use of technology and elastic supply of vehicles and drivers enabled them to cope with uncertainties more effectively.
The study, led by Professor Takashi Miura of Kyushu University, has discovered that interdigitated cell boundaries have a mathematically scaling pattern with self-similarity. The team used the Edwards-Wilkinson model to simulate and understand the molecular mechanism responsible for these dynamics.
A team of researchers analyzed stone artefacts from Vanuatu, Solomon Islands, and Caroline Islands to understand relationship between western Pacific Polynesian societies. Geochemical analysis revealed six adzes sourced from a single fortified quarry complex in American Samoa, indicating long-distance mobility.
A new study published in PLOS ONE found that a heart injury biomarker, cardiac troponin, can identify low-risk COVID-19 patients who have normal troponin levels, potentially helping doctors send them home safely. The study suggests that elevated troponin levels may not accurately predict individual patient risk of death.
Researchers developed DeMAG, an open-source web server facilitating accurate interpretation of genetic mutations in disease genes. The tool reduces false positives by integrating structural and evolutionary features, enabling medical professionals to make informed clinical decisions.
Researchers from University of Colorado Boulder identified a fossil chili pepper that may rewrite the geography and evolutionary timeline of the tomato plant family. The team's findings suggest that chili peppers were present in North America at least 50 million years ago.
A study of neuroptera larvae over 100 million years reveals a complex pattern of loss of morphological diversity, with some lines diversifying and gaining importance. The findings suggest that actual diversity was likely substantially greater in the past.
A 25-year longitudinal cohort study revealed that youths involved with the juvenile justice system have a significantly increased risk of firearm mortality, with rates varying by sex, race, and ethnicity. Sixteen years after detention, nearly one-quarter of Black and Hispanic males had been injured or killed by firearms.
Researchers have identified specific biomarker patterns in blood samples that are unique to severe COVID-19 infection and Multisystem Inflammatory Syndrome in Children (MIS-C) in children. These findings may lead to the development of diagnostic tests to predict severe disease and distinguish MIS-C from other conditions.
A new Finnish study found that a green living environment in early childhood does not prevent eczema, despite previous expectations. The study associated coniferous forests and agricultural areas with an elevated risk of eczema, particularly for children born in the spring.
A novel full-spectrum Cell-free RAN (CF-RAN) architecture was proposed, achieving a balance between performance and complexity. The system design and experimental results showed significant performance gains compared to traditional schemes.
A recent study published in Demography found that analyzing birthplace instead of residence reveals significant geographic disparities in mortality. The research suggests that interstate migration reduces regional inequalities, making them less visible in previous studies.
Scientists found that cells use helper molecules to repair damaged ribosomes caused by oxidative stress, fixing the damage and restoring protein production. This discovery has implications for understanding diseases such as cancer and aging.
A study from Lund University found Swedish obstetricians and gynecologists have a significantly higher emotional stability and conscientiousness compared to the general population. This difference affects their decision-making styles in acute childbirth situations.