A new theorem helps system designers make informed decisions about consistency and availability trade-offs in networks. The CAL theorem provides a quantitative relationship between these factors, allowing for more efficient and reliable network designs.
Researchers in Southern Nevada have detected Candida auris genetic material in untreated sewage samples from seven wastewater treatment facilities. The fungus was also found in nearly 80% of untreated sewage samples, indicating its spread in the region. Wastewater surveillance may provide an early warning system for public health actio...
Adults hospitalized with Omicron had a higher death rate than those with seasonal influenza, even though Omicron is considered less virulent. The study found patients hospitalized with Omicron were older and had more underlying illnesses, which may contribute to the higher mortality rate.
The MATISSE study found that administering the Pfizer Bivalent Prefusion F Vaccine in pregnancy reduces severe RSV-associated lower respiratory tract infection by 82% in infants aged six months old. This vaccine is particularly important in low- and middle-income countries where the burden of RSV illness is highest.
Scientists at the University of Colorado Anschutz Medical Campus identified protein FAM193A as a key component of a mechanism suppressing tumor growth. The discovery offers new potential for cancer therapies targeting p53, a frequently mutated gene in human cancers.
A new international study has revealed significant potential for digital technology to improve asthma control for patients. The study found that combining information from a digital device in a digital platform led to improved medication adherence and reduced healthcare costs.
Researchers at Duke University have produced the world's first fully recyclable printed electronics that replace hazardous chemicals with water in the fabrication process. The demonstration points to a path towards reducing environmental footprint and human health risks in the electronics industry.
Scientists have developed a system called PhAST, which uses light-emitting enzymes and ion channels to transmit information between neurons. This method has shown promising results in restoring communication in defective circuits and modifying animal behavior.
A new study found that the 2021 heat wave in Washington state contributed to an additional 159 injury deaths due to indirect causes such as drownings and violence. The researchers recommended increasing funding for cooling centers and mental health services to prevent injuries caused by heat waves.
Researchers at Universitatsklinikum Bonn used CRISPR gene scissors to identify NAE1 as a driver of cisplatin resistance in testicular cancer. Inhibiting this protein with MLN4924 restores cisplatin's effectiveness and has an additional killing effect on tumor cells, offering new treatment options.
Researchers found that obstructive sleep apnea (OSA) can cause premature cognitive decline in middle-aged men, including poorer executive functioning and social cognition. The study suggests that OSA itself is sufficient to cause these deficits, rather than being solely attributed to co-morbidities.
A study from Indiana University School of Medicine found that people with NAFLD have significantly decreased levels of the liver enzyme CYP2C19, which is important for medication processing. This decrease may lead to slower clearance of certain medications and reduced effectiveness of medicines like antidepressants and clopidogrel.
A study published in Annals of the American Thoracic Society has identified disparities in patients receiving extracorporeal membrane oxygenation (ECMO) treatment for severe respiratory illness. Men and those with private health insurance are more likely to receive ECMO, while women and Medicaid recipients are less likely.
Research highlights gaps in knowledge about the relationship between gender and energy, limiting policymakers' actions and exacerbating inequality. Women's access to finance, education, and household bargaining power can increase adoption of efficient cooking technologies and cleaner fuels.
Researchers have identified a probiotic that can protect Caribbean corals from stony coral tissue loss disease (SCTLD), a deadly and rapidly spreading affliction. The probiotic treatment has been shown to stop or slow the progression of the disease in infected coral fragments, offering an antibiotic-free alternative.
Researchers have developed a new way to create dynamic ultrahigh-density 3D holographic projections, overcoming two long-existing bottlenecks in current digital holographic techniques. The new method enables realistic representations of the world around us for use in virtual reality and other applications.
A study by Chalmers University of Technology and Lund University shows that phasing out coal is necessary to limit global warming to 2 degrees. However, current commitments from countries are not sufficient, and China and India need to take rapid action within five years.
A research team led by Dr Chaogu ZHENG from the University of Hong Kong studies the transcriptome age of C. elegans at the single-cell level, revealing insights into cellular basis of 'hourglass' pattern of animal development and evolutionary relationship among cell types.
Researchers discovered how our brain makes new decisions by applying stored knowledge to novel situations. The study found that individuals use both spatial and temporal relationships learned from past experiences to inform their choices.
Researchers at UW-Madison developed a model of how catalytic reactions work at the atomic scale, potentially allowing for more efficient catalysts and enormous energy savings. The new framework challenges established assumptions about catalysis, its relevance to non-metal catalysts, corrosion, and tribology.
Scientists at RIKEN have developed a new technique for creating complex 3D organoids using a cube-like structure made of hydrogels. This innovation enables researchers to control the environment around cells, allowing for the creation of tissues with faithful reproduction of asymmetric genetic expression. The technology has the potenti...
A team of researchers at the University of Illinois has developed a bio-inspired model that simulates variable stiffness flaps on an airfoil to improve lift. The study used reinforcement learning to optimize the stiffness levels, resulting in significant improvements compared to traditional single-stiffness models.
A study published in Scientific Reports found that ChatGPT's statements can significantly influence users' moral judgements. Participants were presented with moral dilemmas and asked whether the statement they read influenced their answers.
A study by the University of Houston found that Black restaurateurs were 76% less likely to succeed in using crowdfunding sources before the Black Lives Matter movement rose to prominence. However, after the movement's endorsement on Kickstarter, funding success for Black-owned restaurants increased nearly four times.
Researchers have derived a formula predicting the effects of environmental noise on quantum computing. By incorporating redundancy in quantum messages, scientists can now quantify how much redundancy is needed to protect against dephasing noise.
A new machine learning model estimates optimal treatment timing for sepsis, taking into account vital signs and lab test results to predict patient survival. The model was trained on a dataset of over 14,000 individuals with sepsis and showed improved outcomes when actual treatment matched the recommended timeline.
Scientists discover that cancer cells use an alternative sugar breakdown pathway when GAPDH is inactivated by oxidative stress, enabling them to tolerate high levels of oxidants. This mechanism also protects cancer cells from chemotherapy and radiotherapy.
Researchers predictably synthesized broadband white-light-emitting perovskites using a steric hindrance regulation strategy, exhibiting tunable emission from 400 to 800 nm. The approach opens a general way to directed synthesis of abundant white-light-emitting perovskites.
Researchers found that probiotic bacteria Lactobacillus reuteri stimulates cancer-killing T cells by secreting indole-3-aldehyde, which activates a receptor in CD8 cells. A diet rich in tryptophan enhances the effect of immunotherapy on shrinking tumors and prolonging survival.
A global study led by the University of Galway found that sleep problems, including snoring and sleep apnea, can increase the likelihood of having a stroke. The study identified six sleep behaviors associated with an increased risk of stroke.
Researchers from Karolinska Institutet found that people with obesity due to genetic predisposition have a lower risk of cardiovascular disease. The study analyzed data from over 15,000 twins and medical registries, suggesting that genetics may play a role in mitigating the risk of cardiovascular disease.
The University of Texas at El Paso will study the role of obesity and inflammation in pancreatic cancer development, a disease with high mortality rates. The grant aims to develop targeted treatments and preventives, potentially transforming understanding of pancreatic cancer.
Researchers at MIT's Picower Institute have developed a new method to measure consciousness without external stimulation, using a breathing task internally prompted by the subject. This approach detected loss of responsiveness at lower concentrations of anesthetic than previous methods, suggesting it is more sensitive.
Human macrophages use Siglec-14 receptors to recognize and engulf carbon nanotubes, leading to inflammation. The discovery could pave the way for developing safer carbon nanotubes and therapies to prevent inflammatory diseases.
A new study by University of Utah researchers finds that US forests may lose carbon through fire, stress, and insect damage, compromising their role as a climate solution. The study suggests urgent need to update carbon offset protocols with best available science on climate risks.
A team of UBC Okanagan researchers has developed a regional house price mining and forecasting framework (RHPMF) that provides comprehensive reports on neighborhood data. The tool helps users analyze population, social dynamics, housing costs, and historical background to assess the market and make informed decisions.
A new UK study found that wearing surgical masks in a large London hospital during the first 10 months of Omicron activity made no difference to reducing hospital-acquired SARS-CoV-2 infections. Researchers analyzed infection control data and found no significant change in infection rates when mask-wearing policies were removed or cont...
Seismic arrays in California's Long Beach and Seal Beach detected over 1,200 shallow earthquakes, showing the Newport-Inglewood fault splays widely at shallow depths. This suggests that a rupture to propagate to the surface may have multiple paths, implications for earthquake hazard planning.
A comprehensive study across six continents found intercropping to be effective against pests, with cabbage and squash showing the strongest resistance. The analysis of 44 field studies revealed that interspersed planting schemes were more effective than border plantings.
Researchers at UToledo developed a new model to estimate the abundance of rare species like invasive grass carp in freshwater ecosystems. The model helps guide management strategies and provides insight into the effectiveness of control efforts.
Researchers from the Dalian Institute of Chemical Physics have developed a method to create rare earth hydrides with superionic conduction at ambient temperatures. This breakthrough could pave the way for advanced clean energy storage technologies by enabling high-conductivity hydride ion batteries and fuel cells.
A recent study published in PLOS ONE found that smartphone plant identification apps are not accurate enough to rely on when it comes to identifying toxic plants. The researchers developed a repeatable scoring system to assess the accuracy of these apps and found them to be unreliable for this purpose.
Researchers developed a new technique to make solid-state electrolytes safer and more efficient for solid-state batteries, addressing the dendrite growth problem. The new approach creates a barrier layer that slows down dendrite growth and promotes their quick elimination, making the battery safer and more reliable.
Researchers identified potential neurological biomarkers of long COVID-19 in nonhuman primates, which could aid in diagnosis, monitoring, and treatment. The study found elevated proteins associated with neurodegenerative disorders in the brain, cerebrospinal fluid, and blood after SARS-CoV-2 infection.
Researchers have discovered that the amygdala uses specialized neurons to learn about threats and rewards, a finding that could lead to more effective treatments for anxiety and drug addiction. By studying how these neurons respond differently to various stimuli, scientists have gained insights into the brain's reward system.
A UC Riverside-led study finds nearly half of domestic well water users in the Central Valley live in disadvantaged communities with high manganese contamination rates. The highest concentrations are found in private, untreated well water systems, posing health risks to fetuses and children.
A recent study by SMU anthropologist Neely Myers found that ethnoracially minoritized youth are less likely to utilize early intervention programs and more likely to drop out once they begin. Culturally sensitive care can help, but family culture and language play a significant role in healthcare disparities.
A novel small molecule, MK-8722, has been shown to trigger improved muscle health in mice with muscular dystrophy by activating AMPK. This finding highlights the potential of this class of AMPK activators as a cost-effective and efficacious method for DMD treatment.
A study by GIST researchers found that Arctic warming is correlated with severe winters in East Asia and North America. The 'Warm Arctic-Cold Continent' phenomenon will persist but become more difficult to predict under warmer climates.
Research led by The University of Alabama reveals a dense, yet thin, layer of ancient ocean floor surrounding the Earth's core-mantle boundary. This ultra-low velocity zone is denser than the rest of the deep mantle and may play an important role in heat escape from the core.
A cross-sectional study in Tokyo, Japan assessed whether information on COVID-19 prevention measures reached the target audience. The study found that eating and drinking services had challenges disseminating accurate information to their staff.
Researchers at Tufts University have successfully produced bulk fat tissue in a lab that has a similar texture and makeup to natural animal fat. The aggregated fat cells can be fine-tuned to resemble real-life fat within meat, offering a key step towards mass production of cultured meat.
Researchers from the London School of Hygiene & Tropical Medicine found that intramuscular administration of tranexamic acid (TXA) is safe and quickly reaches therapeutic concentrations in pregnant women. Oral TXA was also well-tolerated but took an hour to reach therapeutic blood concentrations.
A new study suggests that exposure therapy can be an effective treatment for adolescents with eating disorders, particularly in reducing anxiety towards food. The study found that exposing patients to feared foods, such as candy bars and pizza, helped decrease their anxiety levels and improved their relationships with food.
A recent study found that a modified Mediterranean ketogenic diet can decrease the risk of Alzheimer's disease by modifying biological pathways linked to the disease. The diet showed robust changes in gut microbiome and reduced levels of gamma-aminobutyric acid, a neurotransmitter associated with Alzheimer's.
Researchers at CZ Biohub SF developed a new diagnostic method for LRTI in children, leveraging machine learning and genomics to identify pathogens with high accuracy. The method uses metagenomic sequencing data to analyze gene expression and microbial abundance, providing a more holistic approach to diagnosing the condition.
A study published in Neurology found that Black, Hispanic, and Asian people with Parkinson’s disease have a lower health-related quality of life compared to white people. The researchers evaluated quality of life using a questionnaire and adjusted for factors such as age, sex, and disease duration.
Scientists from NTU Singapore have developed a sustainable cooling method for servers in data centers, reducing energy consumption and CO2 emissions by up to 26%. The new spray cooling system can handle high computing power servers in smaller spaces, leading to significant space savings and energy efficiency.
Researchers at Simon Fraser University are studying the genes of superbugs to develop new and effective treatments for drug-resistant bacterial infections. The team has discovered new genes responsible for causing disease and infection symptoms in humans, which can be targeted by antivirulence drugs.
Researchers analyzed manillas and found a strong similarity between the metal composition of Benin Bronzes and Portuguese trade prior to the 18th Century. The consistency in metal composition suggests that African metalsmiths were selective about what metal they used, with German brass being the principle source.