Researchers provide a panoramic view of catalytic conversion networks for lignocellulose valorization, highlighting key reaction routes and products. The review aims to facilitate large-scale production and promote sustainable development through collaborative efforts.
The POSTECH team developed a multifunctional tip-enhanced spectroscopy that dynamically controls the physical properties of quasiparticles in 2D materials. This technology increases interlayer excitons' luminous efficiency by 9,000 times and modulates their energy.
Research by State University of New York College of Optometry suggests that reading lacks diversity in visual inputs, potentially leading to myopia development. The study proposes a mechanism where sustained reading reduces activation of ON pathways, causing eye growth beyond its focus plane and blurring vision at far distances.
A study published in Radiology found that ultrasound is an effective standalone diagnostic method for patients with focal breast complaints. The analysis showed that ultrasound alone led to accurate diagnosis in 90% of patients, with over 80% of complaints being benign findings.
Researchers find that patients with destructive nasal lesions may be suffering from cocaine-induced granulomatosis with polyangiitis, a condition often misdiagnosed. Cocaine use can trigger production of antibodies leading to symptoms similar to idiopathic Granulomatosis With Polyangiitis.
The Peking University team has developed a miniature three-photon microscope that successfully captured deep-brain images of freely moving mice. The new device features an innovative optical configuration, maximizing the collection efficiency of scattered fluorescence and achieving low phototoxicity.
A systematic review of clinical trials found that strength training with moderate to vigorous intensity, two or three times a week, can significantly lower blood pressure in hypertensive patients. The study analyzed over 21,000 scientific articles and concluded that effective results appeared around the twentieth training session.
Researchers at the University of Illinois have identified a novel class of ribosomal peptides called daptides, which exhibit hemolytic activity. This discovery opens up new avenues for therapeutic development and highlights the vast potential of undiscovered RiPP classes.
Researchers found that elephants exhibit hallmarks of domestication, including low aggression, empathic behaviour, and social learning. They propose that elephants' massive size and safe environment may have relaxed selective pressures for aggression, allowing for the evolution of prosocial behaviour.
Researchers found that COVID-19 infection leads to rapidly progressive dementia, blurring the lines between different types of dementia. Cortical atrophy and inflammation were key indicators, suggesting previously compromised brains have limited defense against new insults.
Researchers at TUM have developed a method to create mini-hearts in Petri dishes using stem cells. The resulting organoids mimic the earliest stages of human heart development and can be used to investigate congenital heart defects, potentially leading to new treatment methods.
A team at UC San Diego developed a biodegradable polymer system to treat rheumatoid arthritis by working with the immune system. The method uses encapsulated all-trans retinoic acid (ATRA) that transforms disease-causing cells into regulatory T cells.
A study found that monkeys with opposable thumbs were fooled by a sleight-of-hand trick, while those without were not. The French drop trick worked for capuchins and squirrel monkeys due to mirroring in their neural motor system.
In a 50-generation evolutionary experiment, male beetles from lineages with intense sexual selection produced lower quality offspring after DNA-damaging radiation. This suggests that males invest more in competition at the expense of DNA repair, impacting future offspring survival and fertility.
A study found that high deductible health plans may lead women to skip additional testing after an abnormal mammogram finding, particularly those with lower incomes and education levels. This can result in delays in diagnosis and treatment, worsening breast cancer outcomes.
Researchers found that infected mosquito saliva contains molecules called sfRNAs that can blunt the body's immune response. These molecules are injected during the mosquito bite, making it more likely for people to become infected with dengue virus.
Researchers at Ulsan National Institute of Science and Technology (UNIST) have identified seven types of zirconium metal clusters found in MOFs and fourteen potential new metal building blocks. This discovery provides a crucial clue to accelerate the development of carbon-neutral porous materials.
Researchers discuss cortactin's impact on cancer progression by modulating the Wnt5a/ROR1 signaling pathway. Cortactin expression is found in various cancers, including breast and chronic lymphocytic leukemia, suggesting its potential role in promoting metastasis.
During the early phase of the COVID-19 pandemic, prenatal telehealth visits substantially increased. The study found that deliveries in November 2020 had the highest telehealth visit rates during pregnancy.
Researchers used transcranial stimulation to regulate Autonomic Nervous System responses and increase oxygen saturation in hospitalized patients with Covid-19. The treatment improved ANS regulation and reduced symptoms without adverse effects.
Researchers from La Trobe University observed freshwater turtles exhibiting nocturnal basking habits in various locations around the world. The study found that this behavior is widespread among several turtle species and occurs mainly in tropical and subtropical regions, where water temperatures remain warm at night.
Researchers found that using monoclonal antibodies within two days of a COVID-19 diagnosis reduced the risk of hospitalization or death by 39% compared to those who did not receive treatment. This finding suggests that early treatment with monoclonal antibodies significantly reduced the severity of COVID-19.
A University of Michigan-led team found that Gulf offshore oil and gas production has twice the climate warming impact as official estimates, primarily due to methane emissions from older platforms closer to land. Simple steps could mitigate those releases, with actions such as capturing or flaring the gas having outsized climate benef...
Scientists discovered that B cells play a crucial role in controlling tuberculosis (TB) infections by directing helper T cells, known as T follicular helper (Tfh)-like cells, to granuloma tissue in the lungs where they can activate macrophages. This finding holds promise for developing better treatments and vaccines for TB.
A team led by Bill Ballard has published a new study in GigaScience to propose Cooinda, an Alpine dingo, as the model specimen to represent a typical dingo. The study presents genomic and brain imaging data that sheds light on the evolutionary history of dingoes and their domestication process.
A new study found that vaccination significantly reduces the risk of severe COVID-19 illness among nursing home residents aged 85 and older. The study, which examined data from 23,172 fully vaccinated residents, showed that just 5% developed a breakthrough infection, with less than 10% requiring hospitalization or dying within 30 days.
Malith Senevirathne, a PhD student from the University of Huddersfield's Global Disaster Resilience Centre, attended a special reception at Buckingham Palace to celebrate Commonwealth Day 2023. The event highlighted the theme 'Forging a sustainable and peaceful common future' and promoted democracy, human rights, and equality for Commo...
A study from the University of Gothenburg reveals that wastewaters harbor unique characteristics allowing antibiotic resistance genes to evolve. The researchers found key components necessary for gene movement in wastewater samples worldwide, not in human or animal guts.
Researchers found that a combination of IL-22 and IL-1R inhibitors could be a promising treatment for inflammatory bowel diseases like Crohn's disease and ulcerative colitis. The study suggests that targeting both pathways may lead to more effective treatment outcomes.
Researchers have shown lorlatinib to be safe and effective in treating high-risk neuroblastoma with ALK gene mutations. The targeted therapy has led to a major amendment in a phase 3 clinical trial, offering new hope for patients with this often lethal cancer.
Researchers found that monk parakeets lose their social standing after a brief absence, particularly among high-ranking birds. The study, led by Annemarie van der Marel, used networks of aggression and observational studies to quantify bird status in dominance hierarchies.
Research analyzing over 46,000 participants in 68 countries reveals that left-wing individuals are more likely to donate globally and show universalistic generosity, whereas right-leaning people focus on donating to their own country. The study also found that the quality of governance plays a significant role in shaping these behaviors.
A new study reveals that lake-terminating glaciers in the Himalaya have been significantly underestimated, leading to revised estimates of glacier mass loss. The research found a 6.5% underestimation, with some regions experiencing even greater discrepancies, highlighting critical implications for regional water resources.
Researchers from PSI deciphered the structure of an ion channel found in the eye while interacting with calmodulin, a protein that enables cell response to calcium fluctuations. This interaction is believed to be responsible for achieving remarkable sensitivity to dim light.
New research from Washington University School of Medicine reveals that updated booster shots targeting specific COVID-19 variants can elicit a broad antibody response capable of neutralizing new variants. Periodic boosters may be necessary to maintain population immunity as the virus continues to evolve.
A study found bats in disrupted ecosystems are more frequently infected with coronaviruses, linked to chronic stress and loss of resources. Land use changes such as agriculture, deforestation, and energy production increase the risk of bat infection.
A new study models current and future trends in heat-related mortality in the MENA region, predicting a significant increase in deaths under high-emissions scenarios. Limiting warming to 2°C may prevent over 80% of these predicted deaths, highlighting the urgent need for better adaptation policies and renewable technologies.
A new fluorescent probe, TiY, has been developed to selectively target and kill cancer stem cells, which are responsible for tumor growth. The probe can be used to simultaneously diagnose and treat cancer, offering a promising approach to improving cancer treatment outcomes.
A study by Johns Hopkins Medicine researchers found that certain biomarkers in urine and blood can predict the risk of developing chronic kidney disease (CKD) in patients with acute kidney injury (AKI). Higher levels of KIM-1, MCP-1, and TNFRI were associated with a increased risk of CKD progression.
A study published in the journal Cancer found that long-term pancreatic cancer survivors have a robust immune response and enriched gut microbiome species, including Faecalibacterium prausnitzii. The research suggests that these bacterial species may promote immune response to pancreas cancer.
A large UK Biobank study found that poor sleep quality may bolster genetic susceptibility to asthma, potentially doubling the risk. A healthy sleep pattern was associated with a lower risk of asthma, and spotting and treating sleep disorders early on might lessen the risks.
A new case series study found that an 8-week methylation-supportive diet and lifestyle program reduced biological age by 4.60 years, with five of six participants exhibiting significant age reversal. The study suggests that this intervention may favorably influence biological age in both sexes.
A UCLA-led team developed foldable robots using conductive materials, overcoming chip weight and rigidity issues. The OrigaMechs can sense, analyze and act with precision in extreme environments, making them suitable for disaster response and space exploration.
A randomized clinical trial found that a video-based decision support tool increased patient knowledge, but not assent, to ICD implantation among Black patients. The study also highlighted the complexity of aversion to cardiac procedures in Black communities, emphasizing the need for further research on social determinants of health.
A new study by Oregon Health & Science University reveals a significant variance in Medicaid reimbursement rates for mental health services across US states. The study found that Nebraska, Alaska, and Arkansas reimburse at the highest rates, while Pennsylvania, Rhode Island, and Maine reimburse the least for the same set of services.
Astronomers observe repeating radio signal from star YZ Ceti, indicating potential magnetic field of nearby Earth-sized planet YZ Ceti b. The detection provides new insights into the environment around stars and has implications for the search for habitable exoplanets.
A nationwide study in Denmark found that people living with HIV are at double the risk of depression and treatment with electroconvulsive therapy compared to controls. Siblings of PLWH also face an increased risk of depression, use of antidepressants, and suicide, but lower than for PLWH.
Research at the University of Massachusetts Amherst shows that circadian disruption from jet lag can harm adult neurogenesis, which supports learning and memory. The study found that the Cryptochrome 1 gene regulates this process and that misalignment can lead to adverse health effects such as dementia and mental illness.
Researchers developed a robotic finger with high-resolution sensors that capture data along the entire length of each finger. The three-fingered robotic hand can identify objects after just one grasp, with 85% accuracy, using tactile sensing and machine-learning algorithms.
A study published in Frontiers in Surgery finds that patients with schizophrenia and schizoaffective disorder have lower postsurgical mortality than those with Parkinson's disease, suggesting DBS as an ethical option for treatment-refractory cases. Comprehensive consideration of factors is done on a case-by-case basis for successful DBS.
Researchers found that postpartum women prescribed opioids increased by 38%, with stronger prescriptions given during the pandemic. The study highlights concerns over potential opioid abuse among vulnerable women.
Researchers summarize recent progress of organic RTP materials with long lifetime, large Stokes shift, stimuli-responsiveness and potential applications in display, environmental detection and bioimaging. Challenges to overcome include achieving high quantum yield, short lifetime and rich luminous colors.
University of Limerick researchers developed a new strategy to improve the properties of crystalline drugs, making them more soluble and palatable for children. The study focused on treating schistosomiasis, a neglected tropical disease affecting over 250 million people worldwide.
Researchers at USTC create efficient photocatalytic methane halogenation technology to convert methane into valuable chemical products like methanol and pharmaceutical intermediates. The breakthrough technology uses only light, methane, and seawater, making it a promising solution for sustainable energy utilization.
Researchers identified 1,068 transposable element-derived transcripts with potential to produce tumor antigens that could serve as targets for new immunotherapies. Many of these candidate proteins were present in multiple tumors and across tumor types, suggesting a universal antigen-based therapy.
The LSU Health New Orleans Louisiana Tumor Registry released the sixth report of statewide cancer incidence rates by census tract, finding that 81% of tracts met criteria for all cancers combined. Census tracts with statistically higher incidence rates were found in parishes including Orleans, Lafourche, and St. Bernard.
A pharmacy PhD student from Iraq has won the Best Oral Presentation award at a major international conference for pharmaceutical sciences. Haja Muhamad's prize-winning talk explored the effects of prandial dosing on dosage forms using imaging and spectroscopic analysis.
A Yale-led team has developed EN-TEx, a large dataset and annotation resource to understand the impact of genomic variants on disease. The resource leverages high-quality genome sequencing data from four donors to identify variant effects in various tissues.
A Marshall University researcher has received a $388,500 NIH grant to study the effects of binge drinking on brain development and its long-term cognitive consequences. The two-year grant will allow her team to identify mechanisms that drive changes in brain function and explore novel targets for prevention and treatment.
A recent study found that a tiny fragment of the PC1 protein can suppress the disease in mouse models, reducing cyst size and revealing new avenues for developing therapies. The researchers discovered that this small piece interacts with a mitochondrial protein called NNT, opening up new avenues to study its normal function.