A team of researchers has developed a method to map hidden meltwater paths in glaciers, helping predict glacier motion, melting rates, and possible collapses. This improves climate change forecasts and informs coastal ecosystems' adaptation strategies.
A landmark study links iron regulation to a rare blood cancer, revealing that restricting iron access to the bone marrow can reduce red blood cell production in patients with polycythemia vera. Clinical trials are underway for a potential new treatment using a drug that controls iron regulation.
An international research team examined the environmental risks and management of a February 2023 Ohio train derailment that burned vinyl chloride. The team suggests both underestimation and overestimation of environmental risk are unscientific, and proper risk assessment requires comprehensive monitoring data.
A revolutionary investigation has shed light on pioneering female migrants who arrived in Orkney during the Bronze Age. Ancient DNA analysis revealed a major influx of non-local people, dominated by women, challenging previous assumptions about the archipelago's influence during this period.
A research team from Germany, Austria, Canada, and the USA analyzed Troodon eggshells using a new method, revealing that they were produced at temperatures of 42°C and 30°C. The findings suggest that Troodon females laid eggs in communal nests, similar to modern ostriches.
Researchers found a 40% reduction in ammonia emissions and a two-thirds decrease in methane emissions by acidifying slurry with sulfuric acid. The method also improves fertilization and could be optimized to achieve even higher reductions.
Researchers found consistent results between observations and theory, showing that clusters have become more centrally concentrated over time. The study provides strong support for the Lambda-CDM paradigm by demonstrating agreement between the observed and simulated concentration-mass relation of galaxy clusters.
Researchers from Tokyo University of Science reveal the crystal structure of centromere-associated protein E (CENP-E), a promising target for inhibitor therapy. The discovery is expected to facilitate the development of anticancer drugs with fewer adverse effects on patients.
Researchers from the University of North Carolina Health Care announce that patients receiving anti-TNF biologic treatments combined with methotrexate had better outcomes than those treated with adalimumab alone. The study, published in Gastroenterology, provides clear results that can immediately impact patient care.
Scientists at the Light Publishing Center discovered that elliptically polarized pulses can create larger concentrations of anisotropic nanopores in silica glass. This breakthrough allows for faster and lower-energy data storage in 5D optical systems.
Researchers at Rice University have created a new technology called PULSED that can deliver time-released drugs and vaccines for extended periods. The technology uses high-resolution 3D printing and soft lithography to produce microcylinders made of biodegradable polymers, which can be loaded with drugs and release them over time.
A Penn State-led research team developed a statistical method to predict the effects of climate change on cold-blooded animals. The Physiologically Guided Abundance Model (PGA Model) combines field and laboratory data to forecast species geographical distributions and abundance in response to warming temperatures.
A study of 460,000 privately insured postpartum women found that those giving birth after March 2020 were more likely to fill potent opioid prescriptions. This increase was particularly notable among cesarean births, raising concerns about opioid misuse and overdose risk.
Scientists have found that cells break down and reassemble fatty acids to create more beneficial variants, such as oleic acid. This process, called triglyceride cycling, refines poorly usable fatty acids into higher-quality forms.
Researchers found that vitamin D deficiency prevalence ranged between 29-37% among active duty Navy military personnel, with higher rates among submariners. Periodic assessment and supplementation may be necessary to address the issue.
A new study reveals that the squash bee has evolved in response to increased agriculture, particularly squash cultivation. This adaptation allowed its population to expand significantly, making it an essential pollinator of these crops.
Imperial College London physicists have recreated the famous double-slit experiment, showing light behaves as both particles and waves in time. This experiment could lead to ultrafast optical switches and control over light in space and time.
A Virginia Tech researcher has identified a key factor in DiGeorge syndrome, a genetic disorder affecting brain development. The study finds that mitochondrial deficits can be targeted with dietary supplements or more precisely-targeted drugs to support final connections during brain development.
Researchers discovered a single amino acid mutation in glutamate transporter protein causes transient loss of muscle control. The mutation affects the protein's shape and transport rate, leading to reduced glutamate transport and increased anion imbalance in neural cells.
A study reveals that a bacterium produces two molecules to keep microbial competitors at bay, giving it an advantage in colonizing and dominating the root niche. This finding has implications for developing biologicals in agriculture and understanding the inner workings of the plant microbiota.
A recent $800,000 grant from the Missouri Department of Economic Development will train 300 MU students as part-time nurse assistants at MU Health Care. This three-year initiative will create a paid opportunity for nearly 100 MU students each year to earn work experience and reduce the need for student loans.
A recent clinical study found that an online e-health program helped more people with chronic pain reduce their opioid medications and pain intensity than a control group. The program, called Goalistics Chronic Pain Management, improved pain knowledge, confidence managing pain, and coping skills.
A new study from Rutgers University found that 7.2% of hospitalized service members had wounds to their genitals and urinary system, with IEDs responsible for nearly two-thirds of these injuries. Researchers hope to improve protection and treatment for such injuries.
WVU engineers developed a new electrode cuff called MouseFlex to test electric current treatments, overcoming previous challenges with stability and durability. The device can withstand high electrical stimulation and may benefit patients with conditions like rheumatoid arthritis and drug-resistant epilepsy.
The April issue of The American Journal of Psychiatry features studies on mood disorders, psychotic disorders, autism, and stress-related disorders. A special issue of The American Journal of Psychotherapy honors the work of Otto F. Kernberg, M.D.
Researchers have made significant discoveries about DELLA proteins, a family of 'promiscuous' proteins that regulate various plant functions. The study reveals complex interactions between DELLA proteins and transcription factors, which could lead to designing new crops with improved resilience and yields.
The University of Huddersfield has launched a smart rolling stock maintenance research facility to investigate cutting-edge technologies for improving the efficiency and reliability of train maintenance. The facility aims to reduce costs, increase reliability, and make rail travel more affordable.
A study published in Health Affairs found that German hospitals with high quality ratings were more likely to decrease their quality levels, while those with low ratings improved. The authors recommend increasing public access to hospital quality information and promoting its use among referring physicians to drive quality improvement.
Researchers found that statin users can engage in moderate-intensity exercise without exacerbating muscle injury or symptoms. The study's findings are reassuring for people experiencing muscle pain or fatigue from statins and provide important guidance for maintaining physical activity and heart health.
Research finds global emissions of several banned ozone-destroying chemicals are increasing, primarily due to their use in alternative products. These potent greenhouse gases affect the climate, equivalent to CO2 emissions from a smaller country like Switzerland, and may negate some benefits of the Montreal Protocol.
Scientists have detected various prebiotic molecules, including hydrogen cyanide and fullerenes, in the Perseus Molecular Cloud. The presence of these molecules near forming planets could contribute to the formation of complex organic molecules, potentially supplying ancient micro-organisms with the genetic code.
A new study from Mass General Brigham researchers found that early menopause may be a risk factor for Alzheimer's disease dementia. However, women who received hormone therapy around the time of menopause onset did not experience an increased risk of dementia. The study suggests that timing is crucial when it comes to hormone therapy, ...
A new study published in Nature Conservation found that pangolin scales are widely available in Chinese hospitals and pharmaceutical shops, despite a lack of effective regulation. The research reveals that 46% of surveyed hospitals and 34% of surveyed shops were selling pangolin scale products illegally.
A new live attenuated SARS-CoV-2 vaccine administered through the nose has shown better immunity than injected vaccines in hamster models, reducing transmissibility. The vaccine stimulates local immunity by activating antibody immunoglobulin A and memory T cells, providing early protection against COVID-19.
Researchers found that lipid nanoparticles stimulate innate immune cells more efficiently in younger individuals, but less so in older adults. The study suggests that understanding the immune response to LNPs can help develop strategies to improve vaccine responses in the aged population.
Researchers analyzed 2,571 patients treated with monoclonal antibodies and found a 39% reduced risk of hospitalization or death compared to non-treated peers. The study also showed greater benefit in patients with immunocompromising conditions and those treated earlier during the pandemic.
Researchers developed a new reconstruction method for 3D imaging using integrated circuits, enabling non-destructive nanoscale imaging. The approach uses X-ray ptychographic tomography and deep learning to reduce acquisition time and improve fidelity, with potential applications in IC imaging, biology, and material science.
Researchers found that the Wt1 gene plays a key role in the development of endothelial cells during coronary vessel formation. The study's findings suggest that the deletion of this gene disrupts coronary angiogenesis and myocardium development.
Researchers analyzed decades' worth of Landsat imagery to globally attribute recent river regime changes to morphological or hydrological signals. Global-scale prioritization guidance is provided for future river protection and restoration efforts under the UN 2030 Agenda.
Researchers developed a high-speed prediction model combining physical simulations and machine learning, achieving high accuracy without compromising computation time. The technology uses correspondence between input physical conditions and abstract data space handled by machine learning algorithms.
A new study reveals the mechanism of BRCA2's DNA repair function, understanding its role in breast and ovarian cancer development. The findings also provide insights into developing targeted cancer therapies by inhibiting DNA repair mechanisms.
Researchers discovered genetically identical bacterial cells have different functions, with some producing toxins. Nutrient-rich conditions reduce toxin levels and bad actor cells. This finding could lead to alternative antibiotic treatments for animals and humans.
Max Planck scientists explore the possibilities of artificial intelligence in materials science, discussing how combining physics-based modeling with AI can unlock complex material designs. The research focuses on overcoming limitations of traditional methods and handling sparse, noisy data.
Researchers have developed an online tool, the 'Tree-Based Alignment Selector (T-BAS) toolkit', to identify and monitor plant pathogens, including Phytophthora species responsible for devastating plant diseases. The tool provides a living 'tree of life' with genetic sequence data, evolutionary history, and relationships within groups.
A team of researchers has developed non-invasive, 3D-printed graphene-based sensors that can accurately monitor brain activity. The new dry sensors show promise for enabling 'mind-controlled' robots and expanding the applications of brain-machine interfaces.
A comprehensive study found that individuals who maintained their drinking habits during the pandemic had lower prevalence of mental health issues compared to those who abstained or experienced changes. The research also identified groups with stronger associations between alcohol consumption and mental health outcomes.
A study published in JAMA Internal Medicine found that more US prostate cancer patients are choosing active surveillance, a preferred treatment option for low-risk cancers. The study also highlights disparities by race, ethnicity, income, and rurality in receiving active surveillance.
Researchers have overcome a significant barrier to using 2D materials by designing covalent organic frameworks that retain their mechanical properties even when stacked into multiple layers. This breakthrough has the potential to revolutionize various applications, including filtration and battery technology.
A new study by Cornell University researchers found that being a woman or racial minority can help someone stand out in memory, but also increases the likelihood of confusion when others share similar attributes. The findings suggest that biases in memory may contribute to discrimination and have significant implications for career adv...
A recent study by the University of Jyväskylä found that good physical fitness in children does not reduce low-grade inflammation, which is a key factor in childhood obesity. Higher body fat percentage and waist circumference were strongly associated with higher low-grade inflammation levels.
Researchers have linked higher lithium levels in drinking water to a moderately higher risk of autism spectrum disorder in offspring. The study found that mothers living in urban areas had a slightly stronger association between lithium exposure and autism risk.
A recent study found that ocean warming triggers dinoRNAV infections in coral colonies, intensified in unhealthy colonies. This is the first empirical evidence of reef-wide dynamics of viruses infecting coral symbionts during heat waves.
A recent US study found that people living with HIV performed worse on cognitive tests after SARS-CoV-2 infection compared to those without HIV, but these differences were attributable to HIV rather than COVID-19. However, vaccinated individuals experienced declines in processing speed following COVID-19.
A new study reveals that only one affordable prenatal supplement meets nutritional guidelines, but its high cost and complex dosing regimen make it inaccessible to many. The study calls for improved nutritional care during pregnancy and more research on nutrient-dense foods.
A new method using a back propagation neural network improves the accuracy of orbit prediction and position error covariance prediction for space targets. The method reduces prediction errors by up to 170m compared to existing models.
Recent climate change has led to an expansion of marine predator ranges into Arctic waters, resulting in increased species richness and altered community compositions. The study found that apex predators such as whales and sharks have migrated northwards, while mesopredators like fish and crabs showed more limited range shifts.
Researchers developed a non-invasive diagnostic test called PANDORA that accurately identified patients with oral squamous cell carcinoma and pre-cancerous conditions. The test, which measures dielectrophoresis in cells, shows over 92% accuracy in detecting oral cancer.
Researchers engineered a lightweight material by fine-tuning interlayer interactions in 2D polymers, retaining desirable mechanical properties even as a multilayer stack. The material's strong interlayer interaction is attributed to hydrogen bonding among special functional groups.
A new study from the Netherlands Institute for Neuroscience proposes a roadmap to solve the controversy surrounding the human brain's ability to regenerate. Researchers critically discussed and re-analyzed previously published single-cell transcriptomics datasets, revealing that markers used in mouse studies may not be suitable for hum...
Research reveals that cold activates cellular cleansing mechanisms that break down protein clumps, preventing age-related diseases like Alzheimer's and Parkinson's. By modulating proteasome activity, scientists have found a potential therapeutic target for aging and related neurodegenerative disorders.