A team of researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg has combined artemisinin with coumarin to develop an autofluorescent compound that destroys certain malaria pathogens. The new compound is effective against drug-resistant strains and shows promise for treating malaria.
Researchers found that fluvoxamine did not reduce symptom duration in patients with mild to moderate COVID-19, contrary to previous uncertainty. The study analyzed 1,175 participants and used a randomized clinical trial design.
A new study by Griffith University and Andrés Bello University found that surfing contributes significantly to the global economy by improving mental health, with benefits estimated to be valued at ~US$1.0–3.3 billion per year on the Gold Coast. The mental health benefits from surfing comprise 57–74% of the total economic benefits of s...
Researchers at Washington State University have created implantable metals that can kill 87% of bacteria causing staph infections in lab tests. The 3D-printed materials combine titanium with copper and tantalum, offering inherent antibacterial response and improved bone tissue integration.
Researchers propose network-based methodology to contextualize scientific publication impact, allowing for more accurate assessment of interdisciplinary discoveries. The new approach normalizes citation counts, mitigating biases in existing methods.
A new study reveals that younger people are more vulnerable to the effects of high blood cholesterol and hypertension, atherosclerosis can be reversed if risk factors are controlled early enough. The study suggests aggressive control of cardiovascular risk factors at younger ages.
A systematic review of 13 randomized clinical trials found that app-based interventions are effective in treating moderate to severe depression. The study's findings support the use of mobile apps as a practical tool for clinical practice.
A study published at the Radiological Society of North America annual meeting found that higher amounts of visceral abdominal fat in midlife are associated with increased risk of Alzheimer's disease. The research also showed that this type of fat is linked to brain inflammation, which may contribute to the development of the disease.
A new study highlights how perimenopausal women's periods may become unpredictable, heavy, and cause worse premenstrual symptoms. The research suggests that improved education and support are needed to manage these changes, including extra support in the workplace, emotional support from loved ones, and access to support groups.
A unique case of commotio cordis in a Romanian basketball player highlights the condition's rarity and importance of prompt intervention. The case, validated by ECG and video evidence, underscores the need for awareness and education about this reversible cardiac phenomenon.
A new study from UCLA Health researchers demonstrates that repetitive transcranial magnetic stimulation (rTMS) is effective in most patients with major depressive symptoms, starting to alleviate symptoms as quickly as one week. The treatment was found to be associated with a significant response rate of 54% of patients, with early impr...
Researchers developed an integrated wearable sensor device using gold nanowires to measure multiple bio-signals simultaneously. The sensors demonstrated remarkable performance in detecting muscle tremors, heartbeat patterns, and body temperature changes.
Scientists from Max Planck Institute have developed an open-source supercomputer algorithm to solve complex mathematical equations of active matter theory. This enables the study of biological materials' patterning and dynamics in space and time.
Researchers developed a two-step hydrothermal method to transform biomass waste into humic acid, increasing efficiency and reducing dependence on non-renewable resources. The study optimized acidic hydrothermal humification conditions and explored the mechanism of action affecting humification ability in alkaline hydrothermal treatment.
Researchers found interactions between aged red blood cells and brain capillaries can lead to cerebral microbleeds. The study may offer new therapeutic targets for treatment and prevention of conditions like hypertension, Alzheimer's disease, and ischemic stroke.
A study by the Keck School of Medicine of USC found that liver cancer risk increases with each successive generation of Mexican Americans, particularly among men. The research analyzed data from over 30,000 participants and found third-generation Mexicans to be 66% more likely to develop liver cancer than first-generation individuals.
Researchers have developed a method to create switchable and metastable discrete supramolecular structures through chiral self-sorting. The structures exhibit thermo-/mechano-chromism and are based on homochiral dimers with matched propeller-shaped chirality.
Researchers at the University of Adelaide have developed a new software tool called CoreDetector to improve plant breeding through enhanced genome-sequencing powers. The tool can efficiently handle large and evolutionary diverse genomes, allowing for more resilient crops in a changing climate.
Researchers analyzed the chemistry of distant teenage galaxies, finding they are unusually hot and contain unexpected elements like nickel. The study provides insight into galaxy formation and evolution, shedding light on why some galaxies appear 'red and dead' while others continue to form stars.
A recent study published in One Health found that feeding dogs raw meat significantly increases the risk of excreting antibiotic-resistant E. coli, a bacteria that can cause life-threatening infections. The researchers emphasized the importance of proper hygiene and sourcing high-quality meat to reduce this risk.
A groundbreaking study published in JAMA found that excluding aspirin from the antithrombotic regimen for patients with a fully magnetically levitated left ventricular assist device (LVAD) resulted in a significant decrease in major nonsurgical bleeding events. This approach is safe and beneficial, challenging conventional practice and...
A novel aqueous lubricant technology has been developed at the University of Leeds, providing a longer-lasting solution for people with dry mouth conditions. The substance, composed of microgel and hydrogel, binds strongly to the surface of the mouth, reducing desorption and offering up to five times more effective relief.
The study found significant variation in maximum allowable GVW limits for timber trucking across countries, with Japan having the strictest limits. Road transport accounted for 89% of total industrial roundwood moved over long distances, and average transportation costs ranged from 4-24 euros per tonne. The results highlight the need f...
Researchers at Hebrew University of Jerusalem discover that pollutants trigger significant changes in large-scale weather patterns, leading to enhanced radiative forcing. Aerosols stop rain in some areas, causing moisture to move to regions with big clouds, which release heat and strengthen winds.
The new AI system can reliably recognize symbols on cuneiform tablets, allowing for the search and comparison of multiple tablets. This breakthrough enables new research questions and access to ancient texts.
Researchers argue for a 'human-centered AI' approach to co-creativity, balancing automation with human control. They emphasize the need for interdisciplinary research on creativity, ethics, and intellectual property rights in human-AI collaboration.
A genome-wide study of over 1 million people identified dozens of genetic variants linked to cannabis use disorder and related health issues. The study found associations between cannabis use disorder and psychiatric disorders, as well as an elevated risk of developing lung cancer.
Researchers investigated the effects of megafires on California's wildlife habitat, analyzing over 600 species. They found that high-severity fires impacted 100 species, with 16 considered conservation concern, yet some species may find refuge in unaffected habitats.
Researchers at MUSC and Cincinnati Children's have developed a novel colon organoid model with naturally occurring immune cells. The model has the potential to improve treatment outcomes for colon-related diseases such as cancer and IBD by providing a more complete human organoid system that can be used to model inflammation in the colon.
A comprehensive meta-analysis led by Dr. Micheal Sandbank reveals that many low-quality studies are driving intervention recommendations and patient outcomes in early childhood autism care. The study highlights the need for more rigorous research to understand the positive and negative effects of various interventions.
A recent study reveals that over one-quarter of older transgender adults have seriously contemplated ending their lives, highlighting the urgent need for targeted support and interventions. The study found that experiencing challenges in areas such as workplace issues and personal safety significantly increased the odds of contemplatin...
Researchers discovered that cerebellar nuclei make a surprising contribution to associative learning by strengthening connections with mossy fibers. Optogenetic experiments also showed that the nuclei can support well-timed learning. The study's findings have implications for understanding cerebellum function and potential treatments f...
A deep learning model developed by Tokyo University of Science researchers can accurately identify horsehair crab genders, enhancing conservation and farming efforts. The AI approach achieves high precision in classification, even when observing shell side, and could be applied to other species.
A systematic review found that only 203 images of 60 patients were included in 152 studies on psoriasis treatment outcomes over 20 years. The low image sharing rate complicates patient understanding and highlights the need for more clinical images.
A new forecast projects 1060 million people worldwide will live with 'other' musculoskeletal disorders by 2050, increasing healthcare needs and pressures on stretched systems. Research found these conditions are reported higher in females, increase with age, and peak at 60-69 years.
A study by Colorado State University found that redlined communities experience higher maximum noise levels, detrimental effects on urban ecosystems, and increased human health risks like hearing loss and stress. The research highlights the need for equitable planning and noise mitigation to benefit both people and wildlife.
Researchers have successfully observed the operating principle of promoters in a catalytic reaction in real-time. Using high-tech microscopy methods, they visualized individual La atoms' role in hydrogen oxidation. The study revealed that two surface areas of the catalyst act as pacemakers, controlled by promoter lanthanum.
The study identifies five critical risk factors to delta sustainability: land subsidence, population density, ineffective governance, economic capacity, and crop land use. Local and global approaches, combining hard and soft adaptation methods, can mitigate risks.
The new law creates a provisional pathway for International Medical Graduates, reducing barriers to practice and potentially attracting more IMGs. To achieve maximum impact, policymakers must address existing gaps in ensuring IMGs work in physician shortage areas and providing adequate labor protections.
A recent study found that during stringent COVID-19 periods, online searches surged in the health and daily life category. As government policies relaxed, searches shifted towards duty-free and travel-related products. The research team applied PCA to Big Data of internet search activity volume data from NAVER DataLab platform.
A new study highlights the need for increased awareness and vigilance among medical professionals in addressing chronic pain dependency. Patients describe feeling ignored and misunderstood, leading to feelings of shame and guilt.
The Malaria Atlas Project has received a $16 million grant from the Bill & Melinda Gates Foundation to track and tackle malaria globally. The project will focus on boosting research in Sub-Saharan Africa, where malaria is endemic, and strengthening research capacity.
Researchers at Chalmers University of Technology have discovered a new method for capturing proteins in nano-sized traps to study difficult-to-treat diseases. The technique allows for the trapping of hundreds of proteins in a small volume, enabling the study of early development and potential drug countermeasures.
A team of researchers at Weill Cornell Medicine used an AI-based approach to uncover patterns among social determinants of health and their impact on children's health outcomes. The analysis found statistical associations between four broad patterns in social determinants and outcomes relating to child developmental health.
Researchers used a stellate ganglion block to restore the sense of smell in patients with long-COVID, showing near 100% resolution of phantosmia in some patients. The treatment was effective in improving symptoms for up to 49% of patients at three months.
Weaker blasts may release more toxic residues than strong ones, contaminating the ocean and posing threats to marine life. Researchers found that lower-power explosions left behind higher levels of TNT in water and sediment.
A global study reveals that farmworkers in major crop regions are facing increasing exposure to extreme heat and humidity, which can impair their ability to function. The most affected crops are rice and maize, with nearly half of the world's rice cropland already experiencing extreme conditions during the planting and harvest seasons.
A new study analyzing cyberstalking research identified sociodemographic and background factors as the largest contributors to perpetration and victimization. The findings highlight the need for targeted prevention strategies considering overlap between offline violence and cyberviolence. Experts emphasize the importance of allocating ...
Scientists at PNNL introduced a new way to evaluate AI system recommendations by incorporating human experts' insights. Human expertise improved the accuracy of predictions and boosted confidence scores, indicating better decision-making capabilities for machine learning systems.
Researchers Matthew Sikora and Benjamin Bitler aim to understand the genetic risk factor for ovarian cancer that varies greatly among ethnic communities. The five-year project will focus on a specific genetic variant, rs3820282, which has been linked to various gynecologic diseases.
The Korea Institute of Civil Engineering and Building Technology has developed a ceramic nanocomposite material that can absorb NOx and SOx pollutants in an eco-friendly manner. The material can mineralize pollutants into harmless sulfate ions and nitrite ions at room temperature, reducing greenhouse gas emissions.
A recent study published in Nature Communications reveals that disrupted NAD(H) homeostasis is a key factor in tuberculosis pathogenesis. The researchers found that the glycolytic pathway can be selectively inhibited using an LDH enzyme with mostly LDHA subunits, which preferentially converts pyruvate to lactate and NADH to NAD+.
Adults with lower household incomes are less likely to receive cardiologist involvement during heart failure hospitalizations. Socioeconomic factors may influence the quality of care provided to these patients.
Researchers suggest a new evaluation framework to assess AI reasoning abilities, comprising psychological experiments, self-reflection, and source code analysis. This approach aims to determine if AI systems genuinely reason like humans.
Recent studies by Cara Ocobock and Sarah Lacy found that prehistoric women engaged in hunting, with their female anatomy providing advantages such as endurance and fat metabolism. The research corrects the historical erasure of women from the narrative of human evolution.
Researchers at Texas A&M University developed the most comprehensive genome yet for the North American bison, revealing a gene mutation responsible for albinism. The discovery paves the way for understanding genetic variations impacting important traits and informing conservation management.
A recent study by Flinders University researchers found that Generative AI can rapidly create convincing disinformation on health topics, including fake videos and articles.
A new study calls for enhanced transparency in cancer drug trial results to develop better anti-cancer treatments. The multidisciplinary team recommends immediate sharing of participant-level data and public availability of full clinical study reports.
Scientists at the University of Bristol have found a rare phenomenon in purple bronze that could create an ideal 'perfect switch' in quantum devices. The material exhibits emergent symmetry, where it can transition between insulating and superconducting states with temperature changes.
Research finds that poor nutrition contributes to both type 2 diabetes and mental health disorders like depression and anxiety. A balanced diet rich in fruits, vegetables, whole grains, lean protein, and low-fat dairy can reduce the risk of these conditions.