A new kidney function equation has been shown to be more accurate than the old equation in estimating kidney function, particularly for Black individuals. This new equation may reduce racial disparities in cardiovascular disease by making previously ineligible patients eligible for heart failure therapies.
Researchers develop single-use nanoscale system that targets specific bacterium causing ear infections, eliminating most cases without antibiotic use. The system uses hypohalous acid similar to bleach and has shown promise in tests on chinchillas, with potential for future adaptation to prevent recurrent infections.
A new study found that arterial stiffness is a novel cause of premature heart damage among adolescents, leading to increased blood pressure and insulin resistance. The study discovered that adolescents with high arterial stiffness had a 23-27% increased risk of structural heart damage.
A randomized clinical trial of two uterus-sparing procedures in 26 Dutch hospitals has shown that a hundred-year-old method is more effective than a newer procedure. The study found that women who underwent the older Manchester procedure had fewer complications and higher success rates after surgery.
A new study from UC Davis economists shows that immigration to the US did not displace U.S.-born workers in key job sectors. Instead, jobs often filled by migrants remained unfilled, highlighting the need for immigrants to bolster the labor market.
Researchers found that young vapers are at risk of respiratory symptoms such as bronchitic symptoms and shortness of breath, even if they or others around them smoke cigarettes or cannabis. The study also highlights the need for regulatory oversight of vaping products.
A special issue in The Journal of Scientific Exploration presents a range of evidence casting doubt on the historical figure from Stratford as the true author of Shakespeare's works. Historians and literary scholars present alternative theories, including the possibility that 'Will Shakspere' was a pseudonym for another person.
National guidelines recommend mindfulness meditation, yoga, and music therapy for cancer patients experiencing anxiety and depression. The guidelines are based on strong evidence from clinical studies, providing a comprehensive approach to managing these common side effects of cancer treatment.
The Society for Integrative Oncology (SIO) and the American Society of Clinical Oncology (ASCO) recommend mindfulness-based stress reduction, meditation, and mindful movement to treat anxiety and depression symptoms in cancer patients. These interventions have strong evidence supporting their benefits.
Scientists created a unique data process that provides valuable insights into how drugs are processed in the body and their impact on biochemical responses. The approach reveals detailed maps of drug transformation and allows for simultaneous discovery of fate and effects.
A study led by Max-Planck-Gesellschaft researchers uncovered the conditions that trigger curiosity in wild orangutans, including social and environmental factors. Young orangutans were more likely to observe and approach novel objects, while the presence of association partners increased their curiosity.
Researchers synthesized over 50 studies to find that mental simulations using visuals or verbal calls to action improve behavioral intentions and behavior. However, the effectiveness varies depending on the modality, frequency, type of consumption experience, and target populations.
Researchers analyze ancient documents to shed light on the health of Vlad III, the legendary inspiration behind Count Dracula. The study reveals potential signs of respiratory problems and a condition that could have caused him to cry blood.
Researchers found that engaging in activities, expanding social networks, and using technology can lower the risk of loneliness among elderly. However, several risk factors including older age, vision impairment, and depression increased loneliness likelihood.
A new study found that cumulative exposure to extreme heat can worsen cognitive health, particularly among Black older adults and residents of disadvantaged neighborhoods. Researchers analyzed data from nearly 9,500 U.S. adults ages 52 and older, finding a link between high heat exposure and faster cognitive decline in these groups.
Researchers found that the flu blocks lung liquid secretion, allowing staph to infect lungs. Treatment with a CFTR-activating drug like ivacaftor restores liquid secretion and protects against staph infection.
A nationwide program in Ecuador, which replaced gas stoves with electric induction stoves, led to a significant reduction in greenhouse gas emissions and hospitalization rates. The study found that the program resulted in a 7% decline in liquid petroleum gas consumption and a 5% increase in residential electricity usage.
Researchers identified 2476 nonsynonymous mutations in SA-CRC, including four newly discovered driver genes. The study also found distinct genomic profiles of SA-CRC compared to other colorectal cancers.
Researchers investigate how exposure to endocrine-disrupting chemicals in plastics may increase atherosclerosis and CVD risk, particularly in children. The study aims to establish a novel therapeutic target for chemical-induced CVD and explore gene-EDC interactions.
Theoretical physicists at Los Alamos National Laboratory have developed a new quantum computing paradigm that uses natural quantum interactions to process real-world problems faster than classical computers. The approach eliminates many challenging requirements for quantum hardware.
The team's study found consistent wet biases in upper troposphere water vapor depiction across six reanalysis datasets, with the most significant bias over the Tibetan Plateau. The findings highlight the need for improved water vapor simulation in reanalysis data to enhance climate modeling and forecasting accuracy.
A study by Eötvös Loránd University researchers reveals that the iron uptake mechanism by plastids in the absence of light is similar to photosynthesis. This discovery has significant implications for our understanding of plant-based foods as a source of essential iron for humans.
Researchers at Children's Hospital of Philadelphia developed TEQUILA-seq, a cost-effective technology for targeted long-read RNA sequencing. This innovation enables accurate accounting of all RNA molecules emanating from a single gene, crucial for understanding diseases like cancer.
Researchers at Gwangju Institute of Science and Technology have developed a novel mesoporous tantalum oxide-supported iridium nanostructure catalyst for efficient proton exchange membrane water electrolysis. The catalyst exhibits improved oxygen evolution reaction activity, stability, and cost-effectiveness.
A study by the University of Gothenburg found that many expensive cancer drugs have unclear patient benefits, with only one drug showing both increased life expectancy and improved quality of life. The researchers emphasize the need for further discussions on drug approvals to ensure effective use of limited healthcare resources.
A new study from the University of Essex finds that modern parental pressures and expectations are leaving children with less time for independent play. This is leading to concerns about children's development and increased sedentary behavior due to technology. The study suggests a need for a culture shift where policymakers encourage ...
A recent commentary highlights the misconception that vaping is worse for adults who smoke. Experts emphasize the importance of educating adults about relative risks while preventing youth use. For those who can't quit with medications or counseling, transitioning to e-cigarettes may be a less harmful route.
A recent study published in Cell Host and Microbe reveals how flaviviruses hijack human cells to promote replication. The discovery of KAT5γ's critical role in viral replication paves the way for designing inhibitory molecules to stop viral replication.
Core-shell nanostructured Mg-based hydrogen storage materials show excellent kinetics and long-term cycling performances. They can absorb and desorb hydrogen at relatively low temperatures, reducing energy consumption in hydrogen storage and release. The materials have potential to improve Mg-based hydrogen storage systems for various ...
A UCF researcher is developing a new antibiotic to treat tuberculosis and related lung infections. The team aims to create potent antimycobacterial agents that can be administered orally and target drug-resistant strains.
Scientists measured coral calcification rates off Hawaiian Islands at depths of 230-360 feet, finding the lowest rates ever recorded for healthy corals. This is due to the efficient use of calcification by corals like Leptoseris spp., which form thin horizontal skeletons to maximize area in low-light zones.
Experts warn of increasingly sophisticated strategies used by kleptocrats to manage illicit finances, recast public images, and undermine liberal activism. The study identifies 'transnational uncivil societies' that use wealth managers, lawyers, and other enablers to maintain power and legitimacy.
A study by researchers at Cell Press found that nearly 50% of environmentally-oriented users abandoned Twitter after Elon Musk took over the platform. This mass exodus has serious implications for public communication surrounding topics like climate change, biodiversity, and natural disaster recovery.
A new study finds that in-school occupational therapy can create positive learning environments for children with autism by supporting parent-teacher relationships and understanding their unique needs. The therapy helps teachers get to know the child's needs better and facilitate effective communication between parents and schools.
Researchers developed a water-soluble nanoimprint mold to overcome challenges in metasurface fabrication. The novel approach enables high-resolution and high aspect ratio results at an affordable cost.
Scientists have discovered a potential new treatment approach for non-alcoholic fatty liver disease by targeting a receptor called Adgrf1. Overexpressing Adgrf1 improved insulin sensitivity and reduced lipid accumulation in liver cells, suggesting its role in fat metabolism.
Researchers found that participants with MCI performed significantly worse on a test of four types of decision-making abilities compared to those without. The study's findings have broad implications for choices about finances, health care, and other daily decisions.
A French study found that recreational drug use was associated with a nearly 9-fold higher rate of death or need for emergency intervention in cardiac intensive care patients. The study detected various substances in 1 in 10 patients, with cannabis being the most frequently detected substance.
Most U.S. infants requiring intensive care for RSV lower respiratory tract infections were young and healthy, born at term. RSV preventive measures targeting all infants are urgently needed to reduce severe illness burden.
European societies prefer to accept younger, female, Christian asylum seekers who exhibit desirable attributes. Support for refugees has remained stable over time, with no apparent increase in polarization between left-wing and right-wing respondents.
Researchers at Kessler Foundation are conducting novel studies on identity reconstruction, physical and mental fatigue, and upper limb function to improve the lives of individuals with TBI. The studies aim to develop scalable, accessible, and effective interventions using strength-based approaches.
A team of researchers has identified four metabolism-related biomarkers associated with an increased risk of metastatic prostate cancer in men of West African heritage. These findings could lead to improved testing and treatments for patients.
A new study found that around one in five people with compromised immune systems have no COVID-19 antibodies after three or more vaccinations. The MELODY study identified specific groups at higher risk of not producing antibodies, highlighting the need for targeted interventions and booster vaccines.
Most infants admitted to the intensive care unit (ICU) for RSV infections were previously healthy and born at term. Preventative interventions targeting all infants can reduce the burden of severe RSV illness. New treatments such as palivizumab and nirsevimab are being considered.
A new study reveals that biodiversity research is unbalanced, with attention focused on certain species over others. The study analyzed over 3,000 species and found a four-fold difference in scientific papers between the most studied species and those with no publications. Societal interest was more spread out, but still had significan...
Researchers used machine learning algorithms to analyze brain imaging data and identify changes associated with autism spectrum disorder. The study found that the methodology could determine ASD diagnosis with above 95% accuracy, highlighting potential for improved diagnostic methods.
Research identifies key molecular signatures and pathways contributing to skeletal muscle strength loss in females with estrogen deficiency. The study found parallel patterns of inhibition and activation across various signaling pathways, including AMPK and calcium signaling.
Researchers have identified four metabolism-related biomarkers linked to an increased risk of metastatic prostate cancer in Black men. These biomarkers could lead to improved testing and treatments for this high-risk population, who are more than twice as likely to die from the disease.
A team of New Jersey researchers reviewed the evidence on robotic exoskeleton devices for individuals with acquired brain injury, laying out a systematic framework for future research. The review highlights the need for comprehensive approaches to evaluate these devices and their role in improving mobility in individuals with acquired ...
Dr. Yeaman will apply state-of-the-art science to understand and solve antibiotic-resistant Staphylococcus aureus (MRSA) and Candida albicans infections. The new U19 Center program aims to predict individuals at risk of such infections and inform best antibiotic regimens for cures.
Researchers successfully recreated and mathematically validated two molecular languages at the origin of life, opening doors for nanotechnology development. They designed a programmable antibody sensor using multivalency, which detects antibodies over different concentration ranges.
Researchers have developed a novel framework for comparing and contrasting oscillations across different mechanisms, enabling better understanding of brain waves, heartbeats, and other stochastic oscillations. This breakthrough could lead to new insights into neurological disorders such as Parkinson's disease and atrial fibrillation.
Researchers at Carnegie Mellon University have developed a new AI method that uses transformer models to analyze images of human cells. The technology, called subcellular spatial transcriptomics cell segmentation (SCS), accurately identifies individual cells and their constituent parts, revealing critical information about cellular org...
A computational genetic model has been developed to predict individual genetic risk of developing breast cancer based on a woman's genetic profile. The model uses data from a large-scale international study and identifies women at high risk, who may benefit from earlier and more frequent screening.
A new study identifies over 800 bivalve species that humans harvest and find to be more resilient to extinction due to their adaptability in various climates. The researchers highlight the need for sustainable management to preserve these populations, but also warn of potential risks if human demand exceeds their capacity.
A new study examines the association between impulsivity and suicidal risk in Black emerging adults, finding that mindfulness may be a key buffer against negative consequences. The research suggests that mindfulness can help mitigate suicidal ideation by reducing impulsivity, offering hope for improved mental health outcomes.
Researchers found evidence of separate domestication events for Asian rice in different areas, with wild rice species O. rufipogon and O. nivara contributing to the genetic pool. The study provides a new framework for understanding the evolutionary history of domesticated rice.
Researchers developed a method to design weaker transcription factors that work together to activate genes without activating naturally occurring genes. This approach, called cooperative assembly, strengthens the factors as a group but weakens them individually, ensuring targeted gene activation and long-term circuit stability.
The NIH grant will support researchers investigating how exercise can slow the decline of skeletal muscle with age, with a focus on the transcription factor MYC. The study aims to understand the molecular mechanisms underlying exercise-induced rejuvenation of old muscle and its potential applications for promoting youthfulness.
Researchers at SLAC National Accelerator Laboratory have developed a key process for next-gen X-ray lasers, demonstrating the use of synthetic diamond crystal mirrors to steer X-ray pulses around a rectangular racetrack. The achievement marks an important step towards creating brighter and more stable X-ray laser pulses.